Download or read book Brain Wise written by Patricia S. Churchland and published by MIT Press. This book was released on 2002-10-02 with total page 491 pages. Available in PDF, EPUB and Kindle. Book excerpt: Progress in the neurosciences is profoundly changing our conception of ourselves. Contrary to time-honored intuition, the mind turns out to be a complex of brain functions. And contrary to the wishful thinking of some philosophers, there is no stemming the revolutionary impact that brain research will have on our understanding of how the mind works. Brain-Wise is the sequel to Patricia Smith Churchland's Neurophilosophy, the book that launched a subfield. In a clear, conversational manner, this book examines old questions about the nature of the mind within the new framework of the brain sciences. What, it asks, is the neurobiological basis of consciousness, the self, and free choice? How does the brain learn about the external world and about its own introspective world? What can neurophilosophy tell us about the basis and significance of religious and moral experiences? Drawing on results from research at the neuronal, neurochemical, system, and whole-brain levels, the book gives an up-to-date perspective on the state of neurophilosophy—what we know, what we do not know, and where things may go from here.
Download or read book Faith Form and Time written by Kurt P. Wise and published by B&H Publishing Group. This book was released on 2002 with total page 306 pages. Available in PDF, EPUB and Kindle. Book excerpt: Solid biblical and scientific evidence that God created the universe in six twenty-four hour days about 6,000 years ago.
Download or read book The Wisdom in Feeling written by Lisa Feldman Barrett and published by Guilford Press. This book was released on 2002-08-19 with total page 482 pages. Available in PDF, EPUB and Kindle. Book excerpt: The fundamental concern of psychotherapy is change. While practitioners are constantly greeted with new strategies, techniques, programs, and interventions, this book argues that the full benefits of the therapeutic process cannot be realized without fundamental revision of the concept of change itself. Applying cybernetic thought to family therapy, Bradford P. Keeney demonstrates that conventional epistemology, in which casue and effect have a linear relationship, does not sufficiently accommodate the reciprocal nature of causation in experience. Written in an unconventional style that includes stories, case examples, and imagined dialogues between an epistemologist and a skeptical therapist, the volume presents a philosophically grounded, ecological framework for contemporary clinical practice.
Download or read book Wise Girl written by Jamie-Lynn Sigler and published by Gallery Books. This book was released on 2002-08-01 with total page 192 pages. Available in PDF, EPUB and Kindle. Book excerpt: "I am so proud to be Jamie's 'dad.' She is not only a talented actress but also a bright, generous, and inspiring young lady." -- James Gandolfini "Jamie-Lynn Sigler definitely knows how to inspire people....I'm grateful to call her my friend." -- Lance Bass, *N'SYNC SHE'S YOUNG, TALENTED, BEAUTIFUL AND FAMOUS. BUT NOTHING IS THAT SIMPLE... Everyone knows Jamie-Lynn Sigler as Meadow Soprano on the HBO hit television series The Sopranos. But there's so much more to her, as her candid, outspoken autobiography proves. In Wise Girl, Jamie-Lynn reveals both the perks and the pressures that have come with fame, and how uncertain, fearful times have made her stronger, more confident, and able to face life's challenges. Writing openly and from the heart, she describes the emotional and physical toll taken when Lyme disease left the healthy 19-year-old paralyzed at the height of The Soprano's popularity; an obsession with her weight that nearly destroyed her career; and the dark side of overnight success. Her story will both surprise and inspire you. For this wise girl, the key to success isn't just what's on the outside -- it's using your brains, going with your gut, and learning from your experiences, including the mistakes, every day.
Download or read book Drawing The Line written by Steven M. Wise and published by Merloyd Lawrence Books. This book was released on 2002-05 with total page 344 pages. Available in PDF, EPUB and Kindle. Book excerpt: More than just a book about animal rights, this work is about equality, liberty, freedom, and justice expressed within a scientific, religious, legal and philosophical framework.
Download or read book Wise Blood written by Flannery O'Connor and published by Wyatt North Publishing, LLC. This book was released on 1980 with total page 189 pages. Available in PDF, EPUB and Kindle. Book excerpt: Flannery O'Connor (1925-1964) was an American author. Wise Blood was her first novel and one of her most famous works.
Download or read book The Three Secrets of Wise Decision Making written by Barry F. Anderson and published by . This book was released on 2002 with total page 278 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Download or read book Spy written by David Wise and published by Random House Trade Paperbacks. This book was released on 2003-10-14 with total page 346 pages. Available in PDF, EPUB and Kindle. Book excerpt: Spy tells, for the first time, the full, authoritative story of how FBI agent Robert Hanssen, code name grayday, spied for Russia for twenty-two years in what has been called the “worst intelligence disaster in U.S. history”–and how he was finally caught in an incredible gambit by U.S. intelligence. David Wise, the nation’s leading espionage writer, has called on his unique knowledge and unrivaled intelligence sources to write the definitive, inside story of how Robert Hanssen betrayed his country, and why. Spy at last reveals the mind and motives of a man who was a walking paradox: FBI counterspy, KGB mole, devout Catholic, obsessed pornographer who secretly televised himself and his wife having sex so that his best friend could watch, defender of family values, fantasy James Bond who took a stripper to Hong Kong and carried a machine gun in his car trunk. Brimming with startling new details sure to make headlines, Spy discloses: • the previously untold story of how the FBI got the actual file on Robert Hanssen out of KGB headquarters in Moscow for $7 million in an unprecedented operation that ended in Hanssen’s arrest. • how for three years, the FBI pursued a CIA officer, code name gray deceiver, in the mistaken belief that he was the mole they were seeking inside U.S. intelligence. The innocent officer was accused as a spy and suspended by the CIA for nearly two years. • why Hanssen spied, based on exclusive interviews with Dr. David L. Charney, the psychiatrist who met with Hanssen in his jail cell more than thirty times. Hanssen, in an extraordinary arrangement, authorized Charney to talk to the author. • the full story of Robert Hanssen’s bizarre sex life, including the hidden video camera he set up in his bedroom and how he plotted to drug his wife, Bonnie, so that his best friend could father her child. • how Hanssen and the CIA’s Aldrich Ames betrayed three Russians secretly spying for the FBI–including tophat, a Soviet general–who were then executed by Moscow. • that after Hanssen was already working for the KGB, he directed a study of moles in the FBI when–as he alone knew–he was the mole. Robert Hanssen betrayed the FBI. He betrayed his country. He betrayed his wife. He betrayed his children. He betrayed his best friend, offering him up to the KGB. He betrayed his God. Most of all, he betrayed himself. Only David Wise could tell the astonishing, full story, and he does so, in masterly style, in Spy.
Download or read book Transgenesis Techniques written by Alan R. Clarke and published by Springer Science & Business Media. This book was released on 2008-02-05 with total page 346 pages. Available in PDF, EPUB and Kindle. Book excerpt: The past decade has witnessed a spectacular explosion in both the devel- ment and use of transgenic technologies. Not only have these been used to aid our fundamental understanding of biologic mechanisms, but they have also faci- tated the development of a range of disease models that are now truly beginning to impact upon our approach to human disease. Some of the most exciting model systems relate to neurodegenerative disease and cancer, where the availability of appropriate models is at last allowing radically new therapies to be developed and tested. This latter point is of particular significance given the current concerns of the wider public over both the use of animal models and the merits of using genetically modified organisms. Arguably, advances of the greatest significance have been made using mammalian systems—driven by the advent of embryonic stem-cell–based strategies and, more recently, by cloning through nuclear transfer. For this reason, this new edition of Transgenesis Techniques focuses much more heavily on manipulation of the mammalian genome, both in the general discussions and in the provision of specific protocols.
Download or read book Music and Soulmaking written by Barbara J. Crowe and published by Scarecrow Press. This book was released on 2004 with total page 460 pages. Available in PDF, EPUB and Kindle. Book excerpt: Explores new avenues in music therapy. The author discusses connections between music therapy and theorizes that every little nuance found in nature is part of a dynamic system in motion.
Download or read book High Throughput Screening written by William P. Janzen and published by Springer Science & Business Media. This book was released on 2008-02-05 with total page 269 pages. Available in PDF, EPUB and Kindle. Book excerpt: In High Throughput Screening, leading scientists and researchers expert in molecular discovery explain the diverse technologies and key techniques used in HTS and demonstrate how they can be applied generically. Writing to create precisely the introductory guidebook they wish had been available when they started in HTS, these expert seasoned authors illuminate the HTS process with richly detailed tutorials on the biological techniques involved, the management of compound libraries, and the automation and engineering approaches needed. Extensive discussions provide readers with all those key elements of pharmacology, molecular biology, enzymology, and biochemistry that will ensure the identification of suitable targets and screens, and detail the technology necessary to mine millions of data points for meaningful knowledge.
Download or read book Neurobiology of Hyperthermia written by Hari Shanker Sharma and published by Elsevier. This book was released on 2011-09-22 with total page 611 pages. Available in PDF, EPUB and Kindle. Book excerpt: The effects of global warming on human health factors with special regards to our brain function are still not well understood. There is an urgent need to expand our knowledge on the effects of hot environment on our brain functions in healthy and in diseased populations. It is still unclear whether infectious events, traumatic injuries, metabolic diseases, carcinogenic events, cardiovascular and respiratory functions will be adversely affected by the rise in global temperature or whether environmental pollutants, such as nanoparticles entered into our body system will produce more damage at high ambient temperatures. This book aims to answer these questions based on recent research carried out by top experts in the field from the USA (11 chapters), Europe (8) chapters), the Middle East (3 chapters), Asia (2 chapters) and Canada (1). These chapters are written in review style and embedded with the author’s new and original data in relation to the current knowledge in the field. The book is highly interesting to the first time readers, beginners and students alike as well as provides in-depth knowledge to the professionals. In addition, prospects for future research and recommendations are clearly indicated in each chapter for future growth of the subject in this highly emerging new discipline. Describes the importance of brain temperature and hyperthermia in disease processes Presents research on the first observations on Nanoparticles that worsen the outcome of hyperthermia Discusses the effects of hyperthermia on the blood-brain and blood-cerebrospinal fluid barriers
Download or read book Product Strategy and Corporate Success written by C B Rao and published by Notion Press. This book was released on 2019-10-17 with total page 1227 pages. Available in PDF, EPUB and Kindle. Book excerpt: Product strategy is the key driver of business strategy and corporate success. This book brings out several important aspects of product strategy, drawing upon examples from the Indian automobile industry, which is verily the bellwether of the Indian economy. The automobile industry is not only a strategic industry economically but also an instructive industry intellectually. The industry is the cradle of modern management and is a synthesis of various functional strategies. The growth of the automobile industry or, for that matter, any consumer-facing industry lies in its ability to maintain a continuous pipeline of new and innovative products, substantive in functionality and stylistic in appearance. The automobile industry provides the perfect backdrop for discussing products as the core of the corporate business strategy. The global automobile industry, including the Indian automobile industry, is at an inflection point with portends of an unprecedented transformation. The drivers of this transformation are already seen in terms of connected vehicles, autonomous mobility, electric vehicles and digital technologies. The book, through its eighty chapters, demonstrates the synergistic interplay between technology and business, strategy and execution, innovation and inventiveness, enterprise and regulation, indigenization and globalization, structure and process, resourcing and spend, and leadership and management. This interplay would determine India’s ability to become a major player in this transformation. This book will be of interest to industry professionals, policy makers, the academic community and the general public.
Download or read book RT PCR Protocols written by Nicola King and published by Springer Science & Business Media. This book was released on 2008-02-04 with total page 370 pages. Available in PDF, EPUB and Kindle. Book excerpt: Until the mid 1980s, the detection and quantification of a specific mRNA was a difficult task, usually only undertaken by a skilled molecular biologist. With the advent of PCR, it became possible to amplify specific mRNA, after first converting the mRNA to cDNA via reverse transcriptase. The arrival of this technique—termed reverse transcription-PCR (RT-PCR)—meant that mRNA suddenly became amenable to rapid and sensitive analysis, without the need for advanced training in molecular biology. This new accessibility of mRNA, which has been facilitated by the rapid accumulation of sequence data for human mRNAs, means that every biomedical researcher can now include measurement of specific mRNA expression as a routine component of his/her research plans. In view of the ubiquity of the use of standard RT-PCR, the main objective of RT-PCR Protocols is essentially to provide novel, useful applications of RT-PCR. These include some useful adaptations and applications that could be relevant to the wider research community who are already familiar with the basic RT-PCR protocol. For example, a variety of different adaptations are described that have been employed to obtain quantitative data from RT-PCR. Quantitative RT-PCR provides the ability to accurately measure changes/imb- ances in specific mRNA expression between normal and diseased tissues.
Download or read book E coli Gene Expression Protocols written by Peter E. Vaillancourt and published by Springer Science & Business Media. This book was released on 2008-02-02 with total page 347 pages. Available in PDF, EPUB and Kindle. Book excerpt: Peter E. Vaillancourt presents a collection of popular and emerging methodologies that take advantage of E. coli's ability to quickly and inexpensively express recombinant proteins. The authors focus on two areas of interest: the use of E. coli vectors and strains for production of pure, functional protein, and the use of E. coli as host for the functional screening of large collections of proteins and peptides. Among the cutting-edge techniques demonstrated are those for rapid high-level expression and purification of soluble and functional recombinant protein and those essential to functional genomics, proteomics, and protein engineering.
Download or read book Combinatorial Library written by Lisa B. English and published by Springer Science & Business Media. This book was released on 2008-02-04 with total page 380 pages. Available in PDF, EPUB and Kindle. Book excerpt: The continued successes of large- and small-scale genome sequencing projects are increasing the number of genomic targets available for drug d- covery at an exponential rate. In addition, a better understanding of molecular mechanisms—such as apoptosis, signal transduction, telomere control of ch- mosomes, cytoskeletal development, modulation of stress-related proteins, and cell surface display of antigens by the major histocompatibility complex m- ecules—has improved the probability of identifying the most promising genomic targets to counteract disease. As a result, developing and optimizing lead candidates for these targets and rapidly moving them into clinical trials is now a critical juncture in pharmaceutical research. Recent advances in com- natorial library synthesis, purification, and analysis techniques are not only increasing the numbers of compounds that can be tested against each specific genomic target, but are also speeding and improving the overall processes of lead discovery and optimization. There are two main approaches to combinatorial library production: p- allel chemical synthesis and split-and-mix chemical synthesis. These approaches can utilize solid- or solution-based synthetic methods, alone or in combination, although the majority of combinatorial library synthesis is still done on solid support. In a parallel synthesis, all the products are assembled separately in their own reaction vessels or microtiter plates. The array of rows and columns enables researchers to organize the building blocks to be c- bined, and provides an easy way to identify compounds in a particular well.
Download or read book Calcium Binding Protein Protocols written by Hans J. Vogel and published by Springer Science & Business Media. This book was released on 2008-02-04 with total page 346 pages. Available in PDF, EPUB and Kindle. Book excerpt: Calcium plays an important role in a wide variety of biological processes. This divalent metal ion can bind to a large number of proteins; by doing so it modifies their biological activity or their stability. Because of its distinct che- cal properties calcium is uniquely suited to act as an on–off switch or as a light dimmer of biological activities. The two books entitled Calcium-Binding Protein Protocols (Volumes I and II) focus on modern experimental analyses and methodologies for the study of calcium-binding proteins. Both extracel- lar and intracellular calcium-binding proteins are discussed in detail. H- ever, proteins involved in calcium handling (e. g. , calcium pumps and calcium channels), fall outside of the scope of these two volumes. Also, calcium-bi- ing proteins involved in bone deposition will not be discussed, as this specific topic has been addressed previously. The focus of these two books is on studies of the calcium-binding proteins and their behavior in vitro and in vivo. The primary emphasis is on protein chemistry and biophysical methods. Many of the methods described will also be applicable to proteins that do not bind calcium. Calcium-Binding Protein Protocols is divided into three main sections. The section entitled Introduction and Reviews provides information on the role of calcium in intracellular secondary messenger activation mechanisms. Mo- over, unique aspects of calcium chemistry and the utilization of calcium in dairy proteins, as well as calcium-binding proteins involved in blood clotting, are addressed.
