Download or read book NGF and Related Molecules in Health and Disease written by L. Aloe and published by Elsevier. This book was released on 2003-12-10 with total page 563 pages. Available in PDF, EPUB and Kindle. Book excerpt: The book highlights different aspects of current understanding of neurotrophin-receptor signal transduction pathways, including the signaling endosome hypothesis. Findings on the synaptotrophic potential of NGF and related neurotrophins, neurotrophin involvement in neuronal stem cell biology, biological activity of the NGF precursor proNGF, and nociception- and antinociception-associated activity of NGF and/or BDNF are also presented and discussed. Several chapters deal with the involvement of various neurotrophins in the control of different nonneuronal processes, such as immune, inflammatory and allergic reactions, tissue repair and wound healing. The findings showed that neurotrophins play important roles in the pathobiology of a surprising variety of seemingly unrelated non-neurological diseases, including bronchial asthma, rheumatoid arthritis, systemic sclerosis, hair growth disorders, psoriasis, corneal and skin ulcers, atherosclerosis, metabolic syndrome, crush syndrome, and Behçet's disease. There are also chapters on the involvement of NGF and related molecules in neurological diseases, including Huntington's disease, the multiple sclerosis-like model of experimental allergic encephalomyelitis, peripheral neuropathies, neuroblastoma, Parkinson's disease, Alzheimer's disease, and even motion sickness syndrome, also psychiatric disorders, including depression and schizophrenia. Finally, potential important therapeutic benefits are presented, for diabetic neuropathy, gastrointestinal dysmotility, CNS neurodegenerative disease, spinal cord injuries, cutaneous and corneal ulcers, as well as peripheral ischemic vasculopathy.
Download or read book Recent Advances in NGF and Related Molecules written by Laura Calzà and published by Springer Nature. This book was released on 2021-08-27 with total page 302 pages. Available in PDF, EPUB and Kindle. Book excerpt: More than fifty years after its initial discovery by Rita Levi Montalcini and Stanley Cohen and the proposal of the neurotrophic theory, nerve growth factor (NGF) has become the prototype of a family of biologically active molecules called neurotrophic factors (NTFs). This book addresses important advances in NTF research, from basic science to clinical medicine. It focuses mainly on NGF, but also includes individual chapters dealing with the brain-derived neurotrophic factor (BDNF) and ligands of the glial cell line-derived neurotrophic factor (GDNF) family, which have attracted increasing interest in the neuroscience community because of their diverse effects in the normal and diseased brain. In the first part of the book, the authors provide the necessary background for the following chapters and discuss the basic mechanisms and pathways of NGF signal transduction. In the following sections, they then examine the regenerative activity and neuroprotective capacity of NGF during development and in normal and diseased tissues in adulthood and discuss the role of NGF in Alzheimer's disease and nociception. In addition, the role of NGF in processing sensory information and its influence on behavior is further discussed. The book concludes with an overview of the diagnostic and therapeutic potential of NTF in psychiatric disorders and obesity management, as well as a highlight of NGF research in veterinary medicine. Many of the authors of this volume participated in the Second International Rita Levi-Montalcini Meeting, held in Bologna, Italy, in 2019. The book covers a wide range of important topics in past and current NTF research and will appeal to basic researchers and clinicians alike.
Download or read book Life Itself written by Boyce Rensberger and published by Oxford University Press, USA. This book was released on 1996 with total page 314 pages. Available in PDF, EPUB and Kindle. Book excerpt: In Amazing Life, Boyce Rensberger takes readers to the frontlines of cell research with some of the brightest investigators in molecular, cellular, and developmental biology. The hottest topics in biomedical research are covered.
Download or read book Brain Repair written by Donald G. Stein and published by Oxford University Press, USA. This book was released on 1997 with total page 190 pages. Available in PDF, EPUB and Kindle. Book excerpt: Over a half million people each year suffer brain-damaging injuries and diseases--but the outlook for their eventual recovery is far more hopeful than it was just a short while ago. In Brain Repair, three internationally renowned neuroscientists team up to offer an intriguing and up-to-the-minute introduction to the explosive advances being made in the research, technology, and treatment of brain damage. The key to neuroscience's most exciting discoveries to date is a theory that is rapidly gaining adherents in the scientific community--the theory of neuroplasticity. Neuroplasticity stresses that cells throughout the brain can not only regenerate, but can adapt their function to assume critical roles once performed by damaged tissue. In clear, accessible language, the authors show us that the brain manufactures a host of complex chemicals that actually foster growth in damaged brain cells. We visit the laboratories where researchers are untangling the mystery of Parkinson's disease and trying to understand what goes wrong in stroke victims, and why some, thought permanently impaired, show remarkable improvements. In addition, they discuss how even today misguided ideas can adversely affect how physicians treat patients. And, along the way, they detail the fascinating history of how brain structure and functioning has been understood and studied, from prehistoric times to the present. A best-selling volume in France and Mexico, Brain Repair provides a vividly written, wide-ranging look at the leading edge of one of science's most exciting frontiers.
Download or read book Cumulated Index Medicus written by and published by . This book was released on 2000 with total page 1764 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Download or read book Questioning Krishnamurti written by Jiddu Krishnamurti and published by HarperThorsons. This book was released on 1996 with total page 280 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book contains a fascinating collection of dialogues between one of the greatest mystics of the twentieth century and other great influential thinkers.
Download or read book Decoding Darkness written by Rudolph E Tanzi and published by Basic Books. This book was released on 2008-01-07 with total page 314 pages. Available in PDF, EPUB and Kindle. Book excerpt: Working from the intriguing hypothesis that Alzheimer's dementia is the result of a renegade protein-beta amyloid-Tanzi and others set out to find the gene responsible for its production. Decoding Darkness takes us deep into the minds and far-flung labs of many a prominent researcher, offering an intimate view of the high stakes of molecular genetics, the revolution that propels it, the obstacles that threaten to derail it, and the families whose lives are so dependent upon it. Tanzi and Parson ultimately reveal that Alzheimer's, like heart disease, may be effectively treated-even prevented.
Download or read book Index Medicus written by and published by . This book was released on 2004 with total page 1812 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Download or read book International Review of Cytology written by and published by Academic Press. This book was released on 1999-04-19 with total page 310 pages. Available in PDF, EPUB and Kindle. Book excerpt: International Review of Cytology presents current advances and comprehensive reviews in cell biology-both plant and animal. Articles address structure and control of gene expression, nucleocytoplasmic interactions, control of cell development and differentiation, and cell transformation and growth. Authored by some of the foremost scientists in the field, each volume provides up-to-date information and directions for future research. Key Features * Differentiation-Related Changes in the Cell Cycle * Nitric Oxide and Endothelin-1 in Coronary and Pulmonary Circulation * Phosphoinositide Kinases in Higher Plant Cells * Chlamydomonas Cell Cycle Mutants * Cellular Aspects of Trophic Actions in the Nervous System * Conformational Changes of Muscle Contractile Proteins
Download or read book Artificial Intelligence Applications and Innovations written by Ilias Maglogiannis and published by Springer Nature. This book was released on 2020-05-29 with total page 475 pages. Available in PDF, EPUB and Kindle. Book excerpt: This 2 volume-set of IFIP AICT 583 and 584 constitutes the refereed proceedings of the 16th IFIP WG 12.5 International Conference on Artificial Intelligence Applications and Innovations, AIAI 2020, held in Neos Marmaras, Greece, in June 2020.* The 70 full papers and 5 short papers presented were carefully reviewed and selected from 149 submissions. They cover a broad range of topics related to technical, legal, and ethical aspects of artificial intelligence systems and their applications and are organized in the following sections: Part I: classification; clustering - unsupervised learning -analytics; image processing; learning algorithms; neural network modeling; object tracking - object detection systems; ontologies - AI; and sentiment analysis - recommender systems. Part II: AI ethics - law; AI constraints; deep learning - LSTM; fuzzy algebra - fuzzy systems; machine learning; medical - health systems; and natural language. *The conference was held virtually due to the COVID-19 pandemic.
Download or read book Essentials of Interventional Techniques in Managing Chronic Pain written by Laxmaiah Manchikanti and published by Springer. This book was released on 2018-01-04 with total page 711 pages. Available in PDF, EPUB and Kindle. Book excerpt: This comprehensive review covers the full and latest array of interventional techniques for managing chronic pain. Chapters are grouped by specific treatment modalities that include spinal interventional techniques, nonspinal and peripheral nerve blocks, sympathetic interventional techniques, soft tissue and joint injections, and implantables. Practical step-by-step and evidence-based guidance is given to each approach in order to improve the clinician's understanding. Innovative and timely, Essentials of Interventional Techniques in Managing Chronic Pain is a critical resource for anesthesiologists, neurologists, and rehabilitation and pain physicians.
Download or read book Panminerva Medica written by and published by . This book was released on 1990 with total page 244 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Download or read book Herbal Medicine written by Iris F. F. Benzie and published by CRC Press. This book was released on 2011-03-28 with total page 500 pages. Available in PDF, EPUB and Kindle. Book excerpt: The global popularity of herbal supplements and the promise they hold in treating various disease states has caused an unprecedented interest in understanding the molecular basis of the biological activity of traditional remedies. Herbal Medicine: Biomolecular and Clinical Aspects focuses on presenting current scientific evidence of biomolecular ef
Download or read book Psychoneuroimmunology written by Manfred Schedlowski and published by Springer Science & Business Media. This book was released on 2013-11-11 with total page 590 pages. Available in PDF, EPUB and Kindle. Book excerpt: Psychoneuroimmunology is the first textbook to examine the complex functional relationships between the nervous system, the neuroendocrine and the immune system. The international leaders in this field have been brought together to create this pioneering text; each contributing from their area of expertise. The result is a comprehensive yet accessible interdisciplinary introduction to psychoneuroimmunology which also takes you further than the foundations of those fascinating topics by covering the most recent research in HIV/AIDS, autoimmune diseases, and the reactivation of latent herpes viruses. Attention is also given to the effects of behavior such as physical exercise, sleep, acute and chronic stress, and conditioning of immune functions in animals and humans. The whole is brought together with a wealth of cited research studies, and over 200 illustrations.
Download or read book Development of the Nervous System written by Dan H. Sanes and published by Academic Press. This book was released on 2011-01-25 with total page 358 pages. Available in PDF, EPUB and Kindle. Book excerpt: Development of the Nervous System presents a broad and basic treatment of the established and evolving principles of neural development as exemplified by key experiments and observations from past and recent times. The text is organized ontogenically. It begins with the emergence of the neural primordium and takes a chapter-by-chapter approach in succeeding events in neural development: patterning and growth of the nervous system, neuronal determination, axonal navigation and targeting, neuron survival and death, synapse formation and developmental plasticity. Finally, in the last chapter, with the construction phase nearing completion, we examine the emergence of behavior. This new edition reflects the complete modernization of the field that has been achieved through the intensive application of molecular, genetic, and cell biological approaches. It is richly illustrated with color photographs and original drawings. Combined with the clear and concise writing, the illustrations make this a book that is well suited to students approaching this intriguing field for the first time. Thorough survey of the field of neural development Concise but complete, suitable for a one semester course on upper level undergraduate or graduate level Focus on fundamental principles of organogenesis in the nervous system Integrates information from a variety of model systems, relating them to human nervous system development, including disorders of development Systematically develops knowledge from the description of key experiments and results Organized ontologically Carefully edited to be presented in one voice New edition thoroughly updated and revised to include major new findings All figures in full color, updated and revised Specific attention on revising the chapter on cognitive and behavioral development to provide a foundation and outlook towards those very fast moving areas Instructor website with figure bank and test questions
Download or read book The Hostage Brain written by Bruce S. McEwen and published by Rockefeller Univ. Press. This book was released on 1994 with total page 336 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Download or read book Investigative Ophthalmology Visual Science written by and published by . This book was released on 2000 with total page 772 pages. Available in PDF, EPUB and Kindle. Book excerpt:
