Download or read book Lifespan written by David A. Sinclair and published by Atria Books. This book was released on 2019-09-10 with total page 432 pages. Available in PDF, EPUB and Kindle. Book excerpt: A NEW YORK TIMES BESTSELLER “Brilliant and enthralling.”​ —The Wall Street Journal A paradigm-shifting book from an acclaimed Harvard Medical School scientist and one of Time’s most influential people. It’s a seemingly undeniable truth that aging is inevitable. But what if everything we’ve been taught to believe about aging is wrong? What if we could choose our lifespan? In this groundbreaking book, Dr. David Sinclair, leading world authority on genetics and longevity, reveals a bold new theory for why we age. As he writes: “Aging is a disease, and that disease is treatable.” This eye-opening and provocative work takes us to the frontlines of research that is pushing the boundaries on our perceived scientific limitations, revealing incredible breakthroughs—many from Dr. David Sinclair’s own lab at Harvard—that demonstrate how we can slow down, or even reverse, aging. The key is activating newly discovered vitality genes, the descendants of an ancient genetic survival circuit that is both the cause of aging and the key to reversing it. Recent experiments in genetic reprogramming suggest that in the near future we may not just be able to feel younger, but actually become younger. Through a page-turning narrative, Dr. Sinclair invites you into the process of scientific discovery and reveals the emerging technologies and simple lifestyle changes—such as intermittent fasting, cold exposure, exercising with the right intensity, and eating less meat—that have been shown to help us live younger and healthier for longer. At once a roadmap for taking charge of our own health destiny and a bold new vision for the future of humankind, Lifespan will forever change the way we think about why we age and what we can do about it.

Download or read book How and why We Age written by Leonard Hayflick and published by . This book was released on 1996 with total page 0 pages. Available in PDF, EPUB and Kindle. Book excerpt: "How long can humans live? Is immortality possible? Just what is the aging process? The aging and inevitable death of the human body have inspired more myths and outrageous quackery than anything else subject to scientific inquiry. . . . Now comes a most fascinating book, insightful and scholarly, to provide what answers have emerged so far." --San Francisco Chronicle Here, at last, preeminent cell biologist Leonard Hayflick presents the truth about human aging. Based on more than thirty years of pioneering research in the field, How and Why We Age explores not only how our major biological systems change as we grow older, but also examines the intangible alterations in our modes of thinking and feeling, our moods and sexual desires, our personality traits and our memories. With the immediacy of the latest scientific discoveries, Dr. Hayflick explains how aging affects every part of the body, and dispels many of the most persistent aging myths, to show that: * Hearts do not naturally get weaker with age. * Regular exercise and a low-fat diet won't slow aging. * Curing cancer would only add two years to the average sixty-five-year-old American life. Curing heart disease, however would add fourteen years. * Only five percent of people over the age of sixty-five are in nursing homes * No human has lived--or probably can live--past 120 years. Gracefully written, clearly organized, and packed with essential facts and statistics, How and Why We Age is a landmark study of the aging process for readers of all ages. "Written in clear, nontechnical language, it is an excellent introduction to the scientific and demographic literature on this multifacetedsubject." --Nature

Download or read book Why We Age written by Steven N. Austad and published by Wiley. This book was released on 1999-03-25 with total page 0 pages. Available in PDF, EPUB and Kindle. Book excerpt: Why has the life span of the average American increased from 48 to 75 years in this century alone? . . . If the body is a machine that simply wears out, why do some cells seem immortal? . . . Is there an aging gene? And can we control it? . . . Can antioxidants and hormone therapy actually slow the aging process and extend life? Steven Austad s compelling book investigates the history, the theories, and the personalities behind the quest to understand the nature of aging. Here is hard evidence from the front lines of research that science is finally closing in on the fundamental processes of human biology and life. "Austad s book can be read with pleasure and profit by any intelligent person with a smattering of biological knowledge." Science "In this clear, engrossing overview, Austad takes the sting out of a subject that will ultimately capture us all." Publishers Weekly "Why We Age is remarkably rigorous in its analysis and thorough scope. . . . A comprehensive examination of its topic." Science Editors, Amazon.com "The problem with long life is that one keeps getting older; here s an able and clearly written summary of the latest theories on why we age and what might be done to ameliorate the process." Kirkus Reviews

Download or read book How and why We Age written by Leonard Hayflick and published by . This book was released on 1994 with total page 408 pages. Available in PDF, EPUB and Kindle. Book excerpt: Preeminent cell biologist Leonard Hayflick reveals the results of more than thirty years of pioneering research in the field of aging. Gracefully written, clearly organized, and packed with essential facts and statistics, "How and Why We Age" is a landmark study of the aging process for readers of all ages.

Download or read book Ageless written by Andrew Steele and published by Anchor. This book was released on 2021-03-23 with total page 353 pages. Available in PDF, EPUB and Kindle. Book excerpt: “A fascinating look at how scientists are working to help doctors treat the aging process itself, helping us all to lead longer, healthier lives.” —Sanjay Gupta, MD Aging—not cancer, not heart disease—is the underlying cause of most human death and suffering. The same cascade of biological changes that renders us wrinkled and gray also opens the door to dementia and disease. We work furiously to conquer each individual disease, but we never think to ask: Is aging itself necessary? Nature tells us it is not: there are tortoises and salamanders who are spry into old age and whose risk of dying is the same no matter how old they are, a phenomenon known as “biological immortality.” In Ageless, Andrew Steelecharts the astounding progress science has made in recent years to secure the same for humans: to help us become old without getting frail, to live longer without ill health or disease.

Download or read book Aging The Paradox of Life written by Robin Holliday and published by Springer Science & Business Media. This book was released on 2007-05-04 with total page 135 pages. Available in PDF, EPUB and Kindle. Book excerpt: For centuries people have puzzled over the inevitability of human aging. At the end of the 20th century a remarkable scientific discovery emerged, based on a series of important interconnected insights over quite a long period of time. The aim of this book is to dispel ignorance by explaining in non-technical language what are the reasons for aging and the myth of excessive prolongation of life.

Download or read book The Biology of Senescence written by Alex 1920- Comfort and published by Hassell Street Press. This book was released on 2021-09-09 with total page 282 pages. Available in PDF, EPUB and Kindle. Book excerpt: This work has been selected by scholars as being culturally important and is part of the knowledge base of civilization as we know it. This work is in the public domain in the United States of America, and possibly other nations. Within the United States, you may freely copy and distribute this work, as no entity (individual or corporate) has a copyright on the body of the work. Scholars believe, and we concur, that this work is important enough to be preserved, reproduced, and made generally available to the public. To ensure a quality reading experience, this work has been proofread and republished using a format that seamlessly blends the original graphical elements with text in an easy-to-read typeface. We appreciate your support of the preservation process, and thank you for being an important part of keeping this knowledge alive and relevant.

Download or read book The Clock of Ages written by John J. Medina and published by Cambridge University Press. This book was released on 1997-08-13 with total page 352 pages. Available in PDF, EPUB and Kindle. Book excerpt: Anyone who has watched a wrinkle slowly gouge their face like a strip mine, or has been disturbed by a loss of memory, has uncomfortably confronted the human ageing process. The inexorable march of time on our bodies begs an important question: why do we have to grow old? Written in everyday language, The Clock of Ages takes us on a tour of the ageing human body - all from a research scientist's point of view. From the deliberate creation of organisms that live three times their natural span to the isolation of human genes that may allow us to do the same, The Clock of Ages also examines the latest discoveries in geriatric genetics. Sprinkled throughout the pages are descriptions of the aging of many historical figures, such as Florence Nightingale, Jane Austen, Bonaparte and Casanova. These stories underscore the common bond that unites us all: they aged, even as we do. The Clock of Ages tells you why.

Download or read book Epigenetics of Aging written by Trygve O. Tollefsbol and published by Springer Science & Business Media. This book was released on 2009-11-11 with total page 462 pages. Available in PDF, EPUB and Kindle. Book excerpt: Recent studies have indicated that epigenetic processes may play a major role in both cellular and organismal aging. These epigenetic processes include not only DNA methylation and histone modifications, but also extend to many other epigenetic mediators such as the polycomb group proteins, chromosomal position effects, and noncoding RNA. The topics of this book range from fundamental changes in DNA methylation in aging to the most recent research on intervention into epigenetic modifications to modulate the aging process. The major topics of epigenetics and aging covered in this book are: 1) DNA methylation and histone modifications in aging; 2) Other epigenetic processes and aging; 3) Impact of epigenetics on aging; 4) Epigenetics of age-related diseases; 5) Epigenetic interventions and aging: and 6) Future directions in epigenetic aging research. The most studied of epigenetic processes, DNA methylation, has been associated with cellular aging and aging of organisms for many years. It is now apparent that both global and gene-specific alterations occur not only in DNA methylation during aging, but also in several histone alterations. Many epigenetic alterations can have an impact on aging processes such as stem cell aging, control of telomerase, modifications of telomeres, and epigenetic drift can impact the aging process as evident in the recent studies of aging monozygotic twins. Numerous age-related diseases are affected by epigenetic mechanisms. For example, recent studies have shown that DNA methylation is altered in Alzheimer’s disease and autoimmunity. Other prevalent diseases that have been associated with age-related epigenetic changes include cancer and diabetes. Paternal age and epigenetic changes appear to have an effect on schizophrenia and epigenetic silencing has been associated with several of the progeroid syndromes of premature aging. Moreover, the impact of dietary or drug intervention into epigenetic processes as they affect normal aging or age-related diseases is becoming increasingly feasible.

Download or read book Disrupt Aging written by Jo Ann Jenkins and published by Public Affairs. This book was released on 2016-04-05 with total page 274 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book "sets out to change the current conversation about what it means to get older. In it, Jenkins chronicles her own journey, as well as those of others who are making their mark as disrupters, to show readers how we can all be active, financially unburdened, and happy as we get older. It's [a] ... narrative that touches on all the important issues facing people 50+ today, from caregiving and mindful living to building age-friendly communities and attaining financial freedom"--

Download or read book Toward Healthy Aging written by Priscilla Ebersole and published by Mosby Incorporated. This book was released on 2008 with total page 727 pages. Available in PDF, EPUB and Kindle. Book excerpt: As the most comprehensive resource on health promotion and maintenance for older adults and their families and caregivers, Toward Healthy Aging, 7th Edition includes the most current information you need to provide effective holistic care, promote healthy lifestyle choices, and address end-of-life issues. Grounded in the core competencies recommended by the AACN in collaboration with the Hartfound Institute for Geriatric Nursing and using Maslow's hierarchy of needs, this book includes complete coverage of both common and uncommon conditions in the older adult. Towards Healthy Aging also highlights key aging issues with sections devoted to basic physiologic needs, safety and security, the need to belong, self-esteem, and self-actualization. A strong focus on health and wellness emphasizes a positive approach to aging. Disease processes are discussed in the context of healthy adaptation, nursing support, and responsibilities. Careful attention to age, cultural, and gender differences are integrated throughout to help you remember these important considerations when caring for older adults. Up-to-date content on AIDS provides important information on addressing this growing concern among older adults. Consistent chapter is organization with objectives, case studies, critical thinking questions, research, and study questions make information easy to find and use. Assessment guidelines are incorporated throughout in helpful tables, boxes, and forms for quick access. Case studies at the end of most chapters explore realistic patient care scenarios to help you expand your knowledge and understanding. Resource lists and appendices provide opportunities for further research and study. With over 200 illustrations, the full-color design is engaging and easy to read. Healthy People 2010 boxes address healthy aging considerations. Evidence-Based Practice boxes help you incorporate the latest research findings into practice and advise you on how to avoid potentially harmful practices. A Nutritional Needs chapter includes the most current nutritional guidelines for older adults to help you better address patients' nutritional needs. Includes the latest scales and guidelines for assessing the gerontologic patient in the Health Assessment in Gerontological Nursing chapter. Expanded coverage of end-of-life issues helps you meet the needs of older adults and their families and caregivers during this difficult transition. Economics of aging discussions help you better understand the financial challenges your patients may face. The latest pharmacologic and nonpharmacologic pain management information helps you reduce pain and discomfort for your patients and helps you provide more effective care.

Download or read book Time of Our Lives written by Tom Kirkwood and published by Oxford University Press. This book was released on 2001-01-11 with total page 288 pages. Available in PDF, EPUB and Kindle. Book excerpt: By the year 2050 one in five of the world's population will be 65 or older, a fact which presages profound medical, biological, philosophical, and political changes in the coming century. In Time of Our Lives, Tom Kirkwood draws on more than twenty years of research to make sense of the evolution of aging, to explain how aging occurs, and to answer fundamental questions like why women live longer than men. He shows that we age because our genes, evolving at a time when life was "nasty, brutish, and short," placed little priority on the long-term maintenance of our bodies. With such knowledge, along with new insights from genome research, we can devise ways to target the root causes of aging and of age-related diseases such as Alzheimer's and osteoporosis. He even considers the possibility that human beings will someday have greatly extended life spans or even be free from senescence altogether. Beautifully written by one of the world's pioneering researchers into the science of aging, Time of Our Lives is a clear, original and, above all, inspiring investigation of a process all of us experience but few of us understand.

Download or read book Stupid Things I Won t Do When I Get Old written by Steven Petrow and published by Citadel. This book was released on 2021-06-29 with total page 274 pages. Available in PDF, EPUB and Kindle. Book excerpt: For fans of David Sedaris and Nora Ephron, a humorous, irreverent, and poignant look at the gifts, stereotypes, and inevitable challenges of aging, based on award-winning journalist Steven Petrow's wildly popular New York Times essay, "Things I'll Do Differently When I Get Old." Soon after his 50th birthday, Petrow began assembling a list of “things I won’t do when I get old”—mostly a catalog of all the things he thought his then 70-something year old parents were doing wrong. That list, which included “You won’t have to shout at me that I’m deaf,” and “I won’t blame the family dog for my incontinence,” became the basis of this rousing collection of do’s and don’ts, wills and won’ts that is equal parts hilarious, honest, and practical. The fact is, we don’t want to age the way previous generations did. “Old people” hoard. They bore relatives—and strangers alike—with tales of their aches and pains. They insist on driving long after they’ve become a danger to others (and themselves). They eat dinner at 4pm. They swear they don’t need a cane or walker (and guess what happens next). They never, ever apologize. But there is another way... In Stupid Things I Won’t Do When I Get Old, Petrow candidly addresses the fears, frustrations, and stereotypes that accompany aging. He offers a blueprint for the new old age, and an understanding that aging and illness are not the same. As he writes, “I meant the list to serve as a pointed reminder—to me—to make different choices when I eventually cross the threshold to ‘old.’” Getting older is a privilege. This essential guide reveals how to do it with grace, wisdom, humor, and hope. And without hoarding. Praise for Stupid Things I Won't Do When I Get Old: “Unbelievably witty and relatable, I alternated bursting into laughter and placing my hand over my face in horror thinking, Oh my God, is that me? I often say, at this age we have something young people can never have…wisdom. My dear friend, Steven Petrow, has wisdom to share in this honest, funny, wry guide to keep us young at heart, without desperately hanging onto our youth. I am buying this book for all of my friends!” —Suzanne Somers, New York Times bestselling author of A New Way to Age “Stupid Things I Won’t Do When I Get Old is an irreverent, funny, honest look at aging and all the things we take for granted as normal parts of aging. They don’t need to be. If you struggle with getting older and want to find a fresh perspective on lessons learned about what NOT to do as we age, and what TO do to stay young in heart, spirit, mind and body, read this book.” —Mark Hyman, MD, #1 New York Times bestseller author of The Blood Sugar Solution 10-Day Detox Diet, and Head of Strategy and Innovation at the Cleveland Clinic Center for Functional Medicine. “Steven Petrow resolved to do things differently than his parents had when he gets old because he wished they’d been able to enjoy life more. His solution? He created a list! In this book, he shares the secrets to living a full life regardless of our age. It's all about the decisions we make every day. My advice in a nutshell: Read this book and keep it handy.” —“Dear Abby” (Jeanne Phillips), nationally syndicated advice columnist “It’s never too early to imagine what your life will look like as you age. And as I once wrote, ‘We are not hostages to our fate.’ Petrow’s book will help you plan, think, and redefine what it means to get older—and even laugh while doing it.” —Andrew Weil, MD, New York Times bestselling author of Spontaneous Healing and Healthy Aging: A Lifelong Guide to Your Well-Being “Steven Petrow not only has a great attitude about life, he is wise about how to live it. Like me, he says we should embrace our one life 100% and not let a number—our age—get in the way of anything! Steven’s book will help you rethink the word “aging” and approach this next chapter with a positive and proactive attitude. Plus, this book is fun!” —Denise Austin, renowned fitness expert, author, and columnist “Steven’s writing feels like sitting with a friend—one who is unusually gracious, warm and frank.” —Carolyn Hax, author of the nationally syndicated advice column, Carolyn Hax Praise for Steven Petrow: "Steven Petrow's Complete Gay & Lesbian Manners helps gays and straights navigate the subtleties of the same-sex world." —People "Move over, Emily Post! When it comes to etiquette for members of the gay, lesbian, bisexual and transgender community—as well as their straight friends, family members and coworkers--author and journalist Steven Petrow is the authority." —TIME "What could've easily become a novelty book has emerged as an exhaustively researched, essential resource thanks to advice columnist and etiquette expert Steven Petrow." —The Advocate "From having kids to planning funerals, Steven Petrow's Complete Gay & Lesbian Manners has most facets of gay life covered. Ms. Post would approve." —Entertainment Weekly "An indispensable refresher course...on what's proper in modern...life." —Kirkus Reviews

Download or read book Molecular Mechanisms of Aging written by Konrad Beyreuther and published by Springer Science & Business Media. This book was released on 2012-12-06 with total page 327 pages. Available in PDF, EPUB and Kindle. Book excerpt:

Download or read book Why We Age written by Judy Helen Ford and published by . This book was released on 2019-12-10 with total page 212 pages. Available in PDF, EPUB and Kindle. Book excerpt: 'Why we age' explains the biology in an all-inclusive way for the first time. Judy Ford PhD is a geneticist/cell biologist who herself has contributed some significant research in the field of aging. In this book, Judy puts together many of the currently disparate theories and explains how the various 'theories of ageing' need to be considered together. Because of her unusual cross-disciplinary knowledge, she is able to explain how all the pieces of the complex puzzle fit together and make some (sometimes unusual) recommendations for healthier lifestyles.Despite the need to use some medical and scientific terminology, this is book can be easily understood by any intelligent person. It is particularly suitable for anyone with some knowledge of the science of health, and doctors, dentists, nurses, scientists have all found it extremely interesting.A reader (Mary's) perspective: I really enjoyed reading "Why we age - Solving the puzzle of aging" by Dr Judy Ford. Even though I do not have a background in Science, the unfamiliar terms in Section 1 were so clearly and promptly explained in the text that I felt confident to continue reading and understand the solution to the puzzle. The insights promised in Part B possibly causing various disease across the world were thought provoking and the recommendations in Part C can be trusted. In this book, Dr Judy Ford (the academic) becomes Judy Ford (just another woman going through the aging process) who comforts and encourages us all to be more positive and proactive in caring for our own aging bodies and minds. Judy's final words of advice clearly come from her sound empirical evidence and respected research, as much as her personal life experience, keen sense of humor and a refreshing "good old dose of common sense"

Download or read book Providing Healthy and Safe Foods As We Age written by Institute of Medicine and published by National Academies Press. This book was released on 2010-11-29 with total page 192 pages. Available in PDF, EPUB and Kindle. Book excerpt: Does a longer life mean a healthier life? The number of adults over 65 in the United States is growing, but many may not be aware that they are at greater risk from foodborne diseases and their nutritional needs change as they age. The IOM's Food Forum held a workshop October 29-30, 2009, to discuss food safety and nutrition concerns for older adults.

Download or read book Borrowed Time written by Sue Armstrong and published by Bloomsbury Publishing. This book was released on 2019-01-24 with total page 273 pages. Available in PDF, EPUB and Kindle. Book excerpt: As featured on BBC Radio 4's Start the Week 'A rich, timely study for the era of "global ageing"'- Nature The ageing of the world population is one of the most important issues facing humanity in the 21st century – up there with climate change in its potential global impact. Sometime before 2020, the number of people over 65 worldwide will, for the first time, be greater than the number of 0–4 year olds, and it will keep on rising. The strains this is causing on society are already evident as health and social services everywhere struggle to cope with the care needs of the elderly. But why and how do we age? Scientists have been asking this question for centuries, yet there is still no agreement. There are a myriad competing theories, from the idea that our bodies simply wear out with the rough and tumble of living, like well-worn shoes or a rusting car, to the belief that ageing and death are genetically programmed and controlled. In Borrowed Time, Sue Armstrong tells the story of science's quest to understand ageing and to prevent or delay the crippling conditions so often associated with old age. She focusses inward – on what is going on in our bodies at the most basic level of the cells and genes as the years pass – to look for answers to why and how our skin wrinkles with age, our wounds take much longer to heal than they did when we were kids, and why words escape us at crucial moments in conversation.This book explores these questions and many others through interviews with key scientists in the field of gerontology and with people who have interesting and important stories to tell about their personal experiences of ageing.