Download or read book Viruses Vs Superbugs written by T. Häusler and published by Springer. This book was released on 2016-05-24 with total page 307 pages. Available in PDF, EPUB and Kindle. Book excerpt: Each year thousands of people die from bacteria resistant to antibiotics. Alternative drugs are urgently needed. A surprising ray of hope from the past are viruses that kill bacteria, but not us. Award-winning science journalist Thomas Häusler investigates how these long-forgotten cures may help sick people today.
Download or read book Viruses vs Superbugs written by Thomas Häusler and published by Palgrave Macmillan. This book was released on 2006-06-27 with total page 256 pages. Available in PDF, EPUB and Kindle. Book excerpt: In the US alone some 90,000 people die from superbugs--bacteria that have grown immune to antibiotics. Officials agree that this problem will only get worse with time and new alternatives must be found. One alternative that is being considered by scientists is a kind of virus called a bacteriophage. "Phages"--viruses that kill bacteria but not humans--were discovered in 1915. Phage therapy was successfully used for twenty years before the invention of penicillin made them obsolete everywhere but Eastern Europe, where they are still in use today. In its first English translation, this book tells the fascinating story behind the history of the phage, its discovery and development, as well as the strides that are being made to bring the therapy back to the West today.
Download or read book Viruses Vs Superbugs written by T. Häusler and published by . This book was released on 2006 with total page pages. Available in PDF, EPUB and Kindle. Book excerpt:
Download or read book The Perfect Predator written by Steffanie Strathdee and published by Hachette Books. This book was released on 2019-02-26 with total page 346 pages. Available in PDF, EPUB and Kindle. Book excerpt: An electrifying memoir of one woman's extraordinary effort to save her husband's life-and the discovery of a forgotten cure that has the potential to save millions more. "A memoir that reads like a thriller." -New York Times Book Review "A fascinating and terrifying peek into the devastating outcomes of antibiotic misuse-and what happens when standard health care falls short." -Scientific American Epidemiologist Steffanie Strathdee and her husband, psychologist Tom Patterson, were vacationing in Egypt when Tom came down with a stomach bug. What at first seemed like a case of food poisoning quickly turned critical, and by the time Tom had been transferred via emergency medevac to the world-class medical center at UC San Diego, where both he and Steffanie worked, blood work revealed why modern medicine was failing: Tom was fighting one of the most dangerous, antibiotic-resistant bacteria in the world. Frantic, Steffanie combed through research old and new and came across phage therapy: the idea that the right virus, aka "the perfect predator," can kill even the most lethal bacteria. Phage treatment had fallen out of favor almost 100 years ago, after antibiotic use went mainstream. Now, with time running out, Steffanie appealed to phage researchers all over the world for help. She found allies at the FDA, researchers from Texas A&M, and a clandestine Navy biomedical center -- and together they resurrected a forgotten cure. A nail-biting medical mystery, The Perfect Predator is a story of love and survival against all odds, and the (re)discovery of a powerful new weapon in the global superbug crisis.
Download or read book Superbugs written by Matt McCarthy and published by Penguin. This book was released on 2020-06-09 with total page 306 pages. Available in PDF, EPUB and Kindle. Book excerpt: International Bestseller "An amazing, informative book that changes our perspective on medicine, microbes and our future." --Siddhartha Mukherjee, MD, New York Times bestselling author of The Emperor of All Maladies A New York Times bestselling author shares this exhilarating story of cutting-edge science and the race against the clock to find new treatments in the fight against the antibiotic-resistant bacteria known as superbugs. Physician, researcher, and ethics professor Matt McCarthy is on the front lines of a groundbreaking clinical trial testing a new antibiotic to fight lethal superbugs, bacteria that have built up resistance to the life-saving drugs in our rapidly dwindling arsenal. This trial serves as the backdrop for the compulsively readable Superbugs, and the results will impact nothing less than the future of humanity. Dr. McCarthy explores the history of bacteria and antibiotics, from Alexander Fleming's discovery of penicillin, to obscure sources of innovative new medicines (often found in soil samples), to the cutting-edge DNA manipulation known as CRISPR, bringing to light how we arrived at this juncture of both incredible breakthrough and extreme vulnerability. We also meet the patients whose lives are hanging in the balance, from Remy, a teenager with a dangerous and rare infection, to Donny, a retired New York City firefighter with a compromised immune system, and many more. The proverbial ticking clock will keep readers on the edge of their seats. Can Dr. McCarthy save the lives of his patients infected with the deadly bacteria, who have otherwise lost all hope?
Download or read book The Forgotten Cure written by Anna Kuchment and published by Springer Science & Business Media. This book was released on 2011-12-09 with total page 143 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book fills a void. Never before has a comprehensive history of phage therapy—a once-neglected, now resurgent field—been written. Kuchment writes from the perspective of the eager student of history for the common reader.
Download or read book How to Fight Harmful Microbial Bugs and Superbugs written by Alain Fischer and published by Frontiers Media SA. This book was released on 2021-09-01 with total page 209 pages. Available in PDF, EPUB and Kindle. Book excerpt: The evolution of human beings has been shaped to a large extent by microbes. A number of microbes are innocuous or even contribute to our health equilibrium. This is the case of bacteria and viral phages present in our gut. However, several bacteria, viruses, parasites, and fungi are damaging our bodies, causing a number of acute and chronic diseases. Until recently, these bugs represented the main causes of death. Better hygiene, vaccines, antibiotics and other anti-microbial drugs have resulted in a better control or cure of many infections. However, malaria, tuberculosis, and AIDS still represent major threats in several countries and the recent epidemics of Ebola and Zika demonstrate how vulnerable we are to newly emerging viruses. Furthermore, diarrhea and pneumonia caused by bacteria or viruses still kill millions of children worldwide. Most importantly, bacteria resistant to existing antibiotics are multiplying at a high pace and these superbugs are expected to kill more and more people in the coming years. Clearly, we need to develop more effective approaches to tackle bugs and superbugs. Better hygiene and better vaccine coverage must be considered first and education of kids is essential in this respect. This is the main objective of this series of papers published in Frontiers for Young Minds under the heading “How to Fight Harmful Microbial Bugs and Superbugs?”. Another key objective of the collection is to elicit the interest of children for research on innovative anti-microbial therapies and vaccines.
Download or read book Spillover Animal Infections and the Next Human Pandemic written by David Quammen and published by W. W. Norton & Company. This book was released on 2012-10 with total page 591 pages. Available in PDF, EPUB and Kindle. Book excerpt: A masterpiece of science reporting that tracks the animal origins of emerginghuman diseases.
Download or read book Pandemic written by Connie Goldsmith and published by Twenty-First Century Books ™. This book was released on 2018-08-01 with total page 136 pages. Available in PDF, EPUB and Kindle. Book excerpt: Throughout history, several deadly pandemics brought humanity to its knees, killing millions, and recent outbreaks of Ebola and Zika took coordinated international efforts to prevent them from spreading. Learn about factors that contribute to the spread of disease by examining past pandemics and epidemics, including the Bubonic Plague, smallpox Ebola, HIV/AIDS, and Zika. Examine case studies of potential pandemic diseases, like SARS and cholera, and find out how pathogens and antibiotics work. See how human activities such as global air travel and the disruption of animal habitats contribute to the risk of a new pandemic. And discover how scientists are striving to contain and control the spread of disease, both locally and globally.
Download or read book Superbugs written by John DiConsiglio and published by Raintree. This book was released on 2013 with total page 66 pages. Available in PDF, EPUB and Kindle. Book excerpt: Superbugs, bacterial infections and diseases that have become immune to current antibiotics, are becoming more common. What makes a superbug and why are they becoming more frequent? Is there anything we can do to protect ourselves from superbugs? This exciting book answers these questions and more!
Download or read book Phage Therapy A Practical Approach written by Andrzej Górski and published by Springer Nature. This book was released on 2019-10-25 with total page 384 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book gives a detailed yet clear insight into the current state of the art of the therapeutic application of bacteriophages in different conditions. The authors bring in their practical expertise within their respective fields of expertise and provide an excellent overview of the potential and actual use of phage therapy. Topics like economic feasibility compared to traditional antibiotics and also regulatory issues are discussed in far detail. This new volume is therefore a valuable resource for individuals engaged in the medical application of novel phage therapies.
Download or read book Superbug written by Maryn McKenna and published by Simon and Schuster. This book was released on 2010-03-23 with total page 288 pages. Available in PDF, EPUB and Kindle. Book excerpt: LURKING in our homes, hospitals, schools, and farms is a terrifying pathogen that is evolving faster than the medical community can track it or drug developers can create antibiotics to quell it. That pathogen is MRSA—methicillin-resistant Staphyloccocus aureus—and Superbug is the first book to tell the story of its shocking spread and the alarming danger it poses to us all. Doctors long thought that MRSA was confined to hospitals and clinics, infecting almost exclusively those who were either already ill or old. But through remarkable reporting, including hundreds of interviews with the leading researchers and doctors tracking the deadly bacterium, acclaimed science journalist Maryn McKenna reveals the hidden history of MRSA’s relentless advance—how it has overwhelmed hospitals, assaulted families, and infiltrated agriculture and livestock, moving inexorably into the food chain. Taking readers into the medical centers where frustrated physicians must discard drug after drug as they struggle to keep patients alive, she discloses an explosion of cases that demonstrate how MRSA is growing more virulent, while evolving resistance to antibiotics with astonishing speed. It may infect us at any time, no matter how healthy we are; it is carried by a stunning number of our household pets; and it has been detected in food animals from cows to chickens to pigs. With the sensitivity of a novelist, McKenna portrays the emotional and financial devastation endured by MRSA’s victims, vividly describing the many stealthy ways in which the pathogen overtakes the body and the shock and grief of parents whose healthy children were felled by infection in just hours. Through dogged detective work, she discloses the unheard warnings that predicted the current crisis and lays bare the flaws that have allowed MRSA to rage out of control: misplaced government spending, inadequate public health surveillance, misguided agricultural practices, and vast overuse of the few precious drugs we have left. Empowering readers with the knowledge they need for self-defense, Superbug sounds an alarm: MRSA has evolved into a global emergency that touches almost every aspect of modern life. It is, as one deeply concerned researcher tells McKenna, "the biggest thing since AIDS."
Download or read book Biography of Resistance written by Muhammad H. Zaman and published by HarperCollins. This book was released on 2020-04-21 with total page 300 pages. Available in PDF, EPUB and Kindle. Book excerpt: Award-winning Boston University educator and researcher Muhammad H. Zaman provides a chilling look at the rise of antibiotic-resistant superbugs, explaining how we got here and what we must do to address this growing global health crisis. In September 2016, a woman in Nevada became the first known case in the U.S. of a person who died of an infection resistant to every antibiotic available. Her death is the worst nightmare of infectious disease doctors and public health professionals. While bacteria live within us and are essential for our health, some strains can kill us. As bacteria continue to mutate, becoming increasingly resistant to known antibiotics, we are likely to face a public health crisis of unimaginable proportions. “It will be like the great plague of the middle ages, the influenza pandemic of 1918, the AIDS crisis of the 1990s, and the Ebola epidemic of 2014 all combined into a single threat,” Muhammad H. Zaman warns. The Biography of Resistance is Zaman’s riveting and timely look at why and how microbes are becoming superbugs. It is a story of science and evolution that looks to history, culture, attitudes and our own individual choices and collective human behavior. Following the trail of resistant bacteria from previously uncontacted tribes in the Amazon to the isolated islands in the Arctic, from the urban slums of Karachi to the wilderness of the Australian outback, Zaman examines the myriad factors contributing to this unfolding health crisis—including war, greed, natural disasters, and germophobia—to the culprits driving it: pharmaceutical companies, farmers, industrialists, doctors, governments, and ordinary people, all whose choices are pushing us closer to catastrophe. Joining the ranks of acclaimed works like Microbe Hunters, The Emperor of All Maladies, and Spillover, A Biography of Resistance is a riveting and chilling tale from a natural storyteller on the front lines, and a clarion call to address the biggest public health threat of our time.
Download or read book Phage Therapy written by Fouad Sabry and published by One Billion Knowledgeable. This book was released on 2022-10-05 with total page 328 pages. Available in PDF, EPUB and Kindle. Book excerpt: What Is Phage Therapy The therapeutic use of bacteriophages, also known as phage therapy, viral phage therapy, or phagotherapy, may be defined as the treatment of infectious diseases caused by harmful bacteria. This treatment technique arose at the beginning of the 20th century, but following the second world war, it was gradually supplanted by the use of antibiotics in most areas of the globe. Bacteriophages are a kind of virus that attach itself to bacterial cells and then inject their genome into the bacterial cell. Bacteriophages are also known as phages. The bacterial genome is successfully replaced by the genome of the virus, which results in the cessation of the bacterial infection. Because it is unable to replicate, the bacterial cell that is responsible for the infection instead creates extra phages. Phages are only effective against extremely specific bacterial species due to their high level of specificity. How You Will Benefit (I) Insights, and validations about the following topics: Chapter 1: Phage therapy Chapter 2: Antibiotic Chapter 3: Antimicrobial resistance Chapter 4: Bacteriophage Chapter 5: Colistin Chapter 6: Multiple drug resistance Chapter 7: Pseudomonas aeruginosa Chapter 8: Carbapenem Chapter 9: Polypeptide antibiotic Chapter 10: Steffanie A. Strathdee Chapter 11: Enzybiotics Chapter 12: Ceftolozane/tazobactam Chapter 13: Phagoburn Chapter 14: ESKAPE Chapter 15: Cefiderocol Chapter 16: Center for Innovative Phage Applications and Therapeutics Chapter 17: Locus Biosciences Chapter 18: Benjamin Chan Chapter 19: Robert T. Schooley Chapter 20: Martha Clokie Chapter 21: Multidrug-resistant bacteria (II) Answering the public top questions about phage therapy. (III) Real world examples for the usage of phage therapy in many fields. (IV) 17 appendices to explain, briefly, 266 emerging technologies in each industry to have 360-degree full understanding of phage therapy' technologies. Who This Book Is For Professionals, undergraduate and graduate students, enthusiasts, hobbyists, and those who want to go beyond basic knowledge or information for any kind of phage therapy.
Download or read book Missing Microbes written by Martin J. Blaser, MD and published by Henry Holt and Company. This book was released on 2014-04-08 with total page 288 pages. Available in PDF, EPUB and Kindle. Book excerpt: A critically important and startling look at the harmful effects of overusing antibiotics, from the field's leading expert Tracing one scientist's journey toward understanding the crucial importance of the microbiome, this revolutionary book will take readers to the forefront of trail-blazing research while revealing the damage that overuse of antibiotics is doing to our health: contributing to the rise of obesity, asthma, diabetes, and certain forms of cancer. In Missing Microbes, Dr. Martin Blaser invites us into the wilds of the human microbiome where for hundreds of thousands of years bacterial and human cells have existed in a peaceful symbiosis that is responsible for the health and equilibrium of our body. Now, this invisible eden is being irrevocably damaged by some of our most revered medical advances—antibiotics—threatening the extinction of our irreplaceable microbes with terrible health consequences. Taking us into both the lab and deep into the fields where these troubling effects can be witnessed firsthand, Blaser not only provides cutting edge evidence for the adverse effects of antibiotics, he tells us what we can do to avoid even more catastrophic health problems in the future.
Download or read book Infection written by Gerald N. Callahan and published by Macmillan. This book was released on 2006-11-28 with total page 320 pages. Available in PDF, EPUB and Kindle. Book excerpt: Explores how infection shapes our lives and discusses the various ailments linked to infections, the use of infection to treat disease, and the dangers of the overuse of antibiotics.
Download or read book The Forgotten Cure written by Anna Kuchment and published by Springer. This book was released on 2014-03-03 with total page 0 pages. Available in PDF, EPUB and Kindle. Book excerpt: Before the arrival of penicillin in the 1940s, phage therapy was one of the few weapons doctors had against bacterial infections. It saved the life of Hollywood legend Tom Mix before being abandoned by Western science. Now, researchers and physicians are rediscovering the treatment, which pits phage viruses against their natural bacterial hosts, as a potential weapon against antibiotic-resistant infections. The Forgotten Cure traces the story of phages from Paris, where they were discovered in 1917; to Tbilisi, Georgia, where one of phage therapy’s earliest proponents died at the hands of Stalin; to the Nobel podium, where prominent scientists have been recognized for breakthroughs stemming from phage research. Today, a crop of biotech startups and dedicated physicians is racing to win regulatory approval for phage therapy before superbugs exhaust the last drug in the medical arsenal. Will they clear the hurdles in time?
