Download or read book Vectorology for Optogenetics and Chemogenetics written by Mark A.G. Eldridge and published by Springer Nature. This book was released on 2023-02-06 with total page 331 pages. Available in PDF, EPUB and Kindle. Book excerpt: This volume provides an overview of the viral vectors and how they are applied to chemogenetic and optogenetic tools to the study of neural circuits. The chapters in this book are organized into three parts detailing (1) viral vectors, (2) vector modifications and applications, and (3) practical advice for the delivery of viral vectors, verification of injection accuracy, and monitoring of transgene expression. In the Neuromethods series style, chapters include the kind of detail and key advice from the specialists needed to get successful results in your laboratory. Authoritative and cutting-edge, Vectorology for Optogenetics and Chemogenetics aims to be a useful practical guide to researches to help further their study in this field.

Download or read book Gene Therapy for Neurological Disorders written by Fredric P. Manfredsson and published by Humana. This book was released on 2015-11-26 with total page 0 pages. Available in PDF, EPUB and Kindle. Book excerpt: This volume provides a clear and detailed roadmap of how to design and execute a gene therapy experiment in order to obtain consistent results. Chapters in this book disseminate bits of unknown information that are important to consider during the course of experimentation and will answer questions such as: What delivery vehicle do you use?; How will you ensure that your vector retains stability?; What expression system best fits your needs?; What route will you choose to deliver your gene therapy agent?; How will you model the neurodegenerative disorder that you aim to investigate and what are the proven methods to treat these disorders in preclinical models? Written in the highly successful Methods in Molecular Biology series format, chapters include introductions to their respective topics, lists of the necessary materials and reagents, step-by-step, readily reproducible laboratory protocols and tips on troubleshooting and avoiding known pitfalls. Authoritative and thorough, Gene Therapy for Neurological Disorders: Methods and Protocols, is a compilation of protocols and instructive chapters intended to give researchers, clinicians, and students of all levels, a foundation upon which future gene therapy experiments can be designed.

Download or read book Gene Therapy Methods written by M. Ian Phillips and published by Academic Press. This book was released on 2002-02-22 with total page 770 pages. Available in PDF, EPUB and Kindle. Book excerpt: This volume in the prestigious Methods in Enzymology series discusses methods currently used in preclinical and clinical gene therapy. Subjects covered in this book, such as the use of adeno-associated virus delivery for treatment of Parkinson's disease, are topical and are presented in the methods-oriented style popularized by this series. Discusses methods currently used in preclinical and clinical gene therapy Covers the use of adeno-associated virus delivery for treatment of Parkinson's disease

Download or read book Gene Therapy Protocols written by Paul D. Robbins and published by Humana PressInc. This book was released on 1997 with total page 432 pages. Available in PDF, EPUB and Kindle. Book excerpt: Thirty protocols by leading researchers describe in detail all the essential molecular methods for working with gene transfer systems, along with the methods for gene transfer to specific tissue types either in vivo or ex vivo. The easily reproducible methods range from those for specific viral and nonviral for both genetic and acquired diseases, to those concerned with gene delivery to particular tissues. Methods for applying specific therapeutic systems, such as ribozymes and tumor supressor genes for the treatment of AIDS and cancer, are also included in this authoritative collection.

Download or read book Hugo von Hofmannsthal The Incorruptible Servant written by and published by MHRA. This book was released on 2021-12-13 with total page 115 pages. Available in PDF, EPUB and Kindle. Book excerpt: This is the first translation into English of Hugo von Hofmannsthal’s acclaimed comedy Der Unbestechliche. The Incorruptible Servant is a true comedy of action, a well-constructed, fast moving stage play cast in a traditional mould. The action is controlled by a dominant central figure of a complex make-up, somewhat reminiscent of Tartuffe but closer in portraiture to Dostoevsky’s Foma Fomich in The Village of Stepanchikovo. Theodor is cast as the masterful servant in an aristocratic Austrian country estate in the year 1912. He acquires full control of the household and cunningly manipulates his philandering young master and his mistresses in a plot set out to restore order and morality. The comedy shows the mature Hofmannsthal at the height of his achievement as a dramatist.

Download or read book Confronting Capitalism written by Vivek Chibber and published by Verso Books. This book was released on 2022-08-30 with total page 177 pages. Available in PDF, EPUB and Kindle. Book excerpt: A strategic guide to building a more democratic and egalitarian future Why is our society so unequal? Why, despite their small numbers, do the rich dominate policy and politics even in democratic countries? Why is it so difficult for working people to organize around common interests? How do we begin to build a more equal and democratic society? Vivek Chibber provides a clear and accessible map of how capitalism works, how it limits the power of working and oppressed people, and how to overcome those limits. The capitalist economy generates incredible wealth but also injustice. Those who own the factories, hotels, and farms always have an advantage over the people who rely on that ownership class for their livelihoods. This inequality in power and income is reflected in the operation of the state, where capitalists are able to exert their will even under relatively democratic conditions. The most important reason is that states depend on the employment and profits from capitalist enterprise for both finances and legitimacy. Every meaningful victory for working people has been won through collective struggle but collective action is very difficult to coordinate. In the final section of the book, Chibber walks the reader through some of the historical attempts to build socialism and presents a vision of how we might, perhaps against the odds, build a socialist future.

Download or read book The Book of Max written by Max Keiser and published by . This book was released on 2021-12-20 with total page 106 pages. Available in PDF, EPUB and Kindle. Book excerpt: The Book of Max takes readers deep into the rabbit hole of Max Keiser's mind. Take the orange pill and gain insights from Max's life and Bitcoin journey. Through quotes, memes, artwork and his predictions for the future, this book is unlike anything you've read before!

Download or read book Bias aware Teaching Learning and Assessment written by Donna Hurford and published by Critical Publishing. This book was released on 2022-05-16 with total page 94 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book offers university teachers informed and practical strategies for raising awareness of bias in teaching, learning and assessment practices. Conscious and unconscious biases influence judgements, perceptions, decision making and actions, and societal awareness has now turned the spotlight on how higher education (HE) is addressing bias at institutional and individual levels. The urgency to do so is evidenced through recent studies which reveal the extent of the effects of discrimination and exclusion experienced by individual students, groups of students and members of staff. It can be difficult to know where to start and how to sustain effective impact to achieve inclusion, equity and equality of opportunity. This book offers informed and practical strategies for raising awareness of bias in teaching, learning and assessment practices and provides approaches to eliminate, limit and mitigate the negative effects of bias on university students.

Download or read book A Saint in the Family written by Corinna Turner and published by . This book was released on 2021-11-25 with total page 336 pages. Available in PDF, EPUB and Kindle. Book excerpt: FAITH. FORGIVENESS. FREEDOM. Fr. Kyle Verrall has lived his life in the shadow of his famous sister, Margaret-and that's fine by him. But after his kidnapping by Reginald Hill, he must learn to cope not only with his physical injuries, but also with his unwelcome new popularity. Meanwhile, Margaret continues her fight for true democracy. But can she practise what she preaches and forgive her oldest enemy? This volume contains two novellas, A SAINT IN THE FAMILY and PERSISTENCE, which follow on from the events of THE SIEGE OF REGINALD HILL. It also includes five short stories.

Download or read book Ghost Mortem written by ReGina Welling and published by Willow Hill Books. This book was released on 2019-04-26 with total page 237 pages. Available in PDF, EPUB and Kindle. Book excerpt: My name is Everly Dupree and when my marriage fell apart, I did what every normal, red-blooded woman does… I moved back to my hometown and bought a haunted house for the back taxes. Okay, I realize I might have been a bit hasty, but it seemed like a good idea at the time. Then again, so did staying at the Bide A Way Motel until a dead body turned up in the next room. All I wanted was to come home, find a job and start a new life. I didn't plan on getting tied up in the afterlife. Or of solving a murder, but here's what I learned: You might not believe in ghosts, but sometimes they believe in you.

Download or read book The Art of Masamune Shirow Volume 1 Manga written by Jeremy Mark Robinson and published by Crescent Moon Publishing. This book was released on 2021-10-18 with total page 384 pages. Available in PDF, EPUB and Kindle. Book excerpt: THE ART OF MASAMUNE SHIROW VOLUME 1: MANGA by Jeremy Mark Robinson This is a study of the art of Masamune Shirow (real name Masanori Ota, b. 1961, Kobe, Japan), a Japanese artist best known for Ghost In the Shell, Appleseed and Dominion: Tank Police. Masamune Shirow is one of the great creators in the world of Japanese manga and animé - his works have been the basis of several important franchises. Shirow's art is marked by futuristic, cyber-punk settings, fabulous, often eccentric designs, elaborate mecha (such as tanks and mobile suits), attractive warrior women and detailed storytelling (accompanied by his famous, sometimes arcane notes). The Art of Masamune Shirow includes chapters on Shirow's signature works, Appleseed and Ghost In the Shell, and his lesser-known comics, such as Dominion: Tank Police, Orion, Black Magic and Neuro Hard; a biography; Shirow's relation to the Japanese manga industry; and themes such as cyberculture and cyber-punk fiction. The Appleseed comic and the three Ghost In the Shell comics are explored chapter by chapter. Fully illustrated, including many images from Masamune Shirow's whole output, the neglected comics, and Shirow's other works in print publishing, such as the Intron Depot series. The Art of Masamune Shirow is published in three volumes: Volume 1: Manga Volume 2: Animé Volume 3 Erotica Hardcover - full colour laminate cover. Bibliography, resources and notes. 384 pages. www.crmoon.com

Download or read book Georgio and the Bee Party written by Yvette Kinkade and published by . This book was released on 2021-10-30 with total page 18 pages. Available in PDF, EPUB and Kindle. Book excerpt: Have you ever been to a bee party? This is a lyrical, whimsical story with beautiful, colourful illustrations that encourage children to be curiously confident and kind to others. Join Georgio and the native Australian bees for a beautiful get-together of fun in a celebration of grace, imagination and joy.

Download or read book Chocolate Fudge Saves the Sugar Dog written by Robbie Cheadle and published by Tsl Publications. This book was released on 2021-11-26 with total page 36 pages. Available in PDF, EPUB and Kindle. Book excerpt: Sir Chocolate and Lady Sweet's son, Chocolate Fudge, sees one of Lord Humbug's dogs struggling to stay afloat in the hot chocolate pond. Can Chocolate Fudge save the sugar dog from drowning?

Download or read book Their Second Chance written by Stella Gioacas and published by Maple Publishers. This book was released on 2021-12-14 with total page 162 pages. Available in PDF, EPUB and Kindle. Book excerpt: The last time she saw him was six years ago, the day that had forever changed her life, and not in a good way. He didn't want to hear her out back then, and now he was here, in London, where she managed to build a life for herself and her daughter. She spent all this time despising him, and for a good reason. He's last words to her, still echoing in her mind after all these years, "You're a whore, a witch, I never want to lay eyes on you again." Seem like a wound that would never heal. But seeing him again now made her realise that the heart and mind weren't always on the same page, never mind the body.

Download or read book Shayna written by Miriam Ruth Black and published by . This book was released on 2022-01-04 with total page 332 pages. Available in PDF, EPUB and Kindle. Book excerpt: Escaping religious persecution after a pogrom against Jews in Ukraine in 1919, Shayna, a seventeen-year-old, along with her orphaned four-year-old nephew, her fiancé and his mother begin a treacherous journey to reach safety in America.The novel portrays the Yiddish culture of the shtetl and New York's Lower East side as the reader comes to know little Dovid, who lives with the trauma of losing his family; Yussi, who believes God has forsaken him in this new country; and his mother, Manya, who struggles to find a way to fit in America.Shayna's courage and determination hold them together and weaves a rich fabric from their separate threads to make a loving family, a safe place from which to build a new life in a new country.

Download or read book Cremation of the Scarecrow written by Dzikamayi Chando and published by . This book was released on 2022-02-06 with total page 108 pages. Available in PDF, EPUB and Kindle. Book excerpt: Dzikamayi Chando was born and raised in Gweru, Zimbabwe. Some of his works appear in several online literary publications and Cremation of the Scarecrow is his debut collection. 'Cremation of the Scarecrow is an impressively diverse and generous collection that talks to the truths of blackness, the ghetto experience and plight of poverty, unemployment and drug abuse, dilemma of immigration, identity crisis and discovery of self, depression and death, love and hope, to name but a few. Chando's metaphoric luminosity offers invasively honest perspectives of life as he sees it: "We are lustful angels only here for a one night stand with death, we catch gold fever and comb the dust for death leaping into gloomy mirrors like ghosts muddled by their own darkness." (Gaslighting the Alchemist) Chando's employment of auditory, tactile and visual imagery is second to none. His voice, often ethereal, carries messages transcending lifetimes and realms to deliver powerful instructive memoranda to the unenlightened juvenile and imprudent, the prejudiced gatekeepers, power-hungry fascist dictators and so forth: "This poetry is prophecy of my ancestor's bones falling from his hands like rinsed meteorites spilling out of the nomenclator's mouth his bellow bursting into a trance vibrating in my veins five centuries later... This poetry is DNA- a preserved message on the cusp of a falling sky, a failing realm." (The Reading) Refreshingly, it is Chando's custom to pay homage to women, venerating feminine sacredness, shunning societal norms that disadvantage them, illuminating their mental health challenges and empowering them. In his own words to me, "Women are the grass where two elephants are fighting, victims of their own ignorance in oppressive politics, culture and religion." I find it enchanting that in his poems, Chando often personifies his messages of love and hope as women: "everyone's a poet i'm just the selfish one who took everything from mother's womb these words they bleed to cleanse the place of their origin period" (Womb of the Words) Cremation of the Scarecrow is a honeyed acerbic journey of self-discovery, Chando's overriding missive being, to find your life purpose, you must be able to control the fire.' By Samantha Rumbidzai Vazhure Editor

Download or read book The Healing Box written by Paul Reed and published by Trilogy Christian Publishing. This book was released on 2020-12-27 with total page 286 pages. Available in PDF, EPUB and Kindle. Book excerpt: After arriving home from a tour of combat duty in the traumatic, tangled jungles of Vietnam, returning to a pre-war status as a civilian seemed unattainable, hopeless. Finally, about the time all hope in living had disappeared... a long-forgotten box was brought down from the attic. What I discovered inside the box brought shining rays of light into my dark soul. My journey of healing and transformation started that day because I had entrusted the box some twenty years earlier to "other hands" in the midst of unspeakable, unimaginable violence. While reading The Healing Box, you'll discover some of the many extraordinary and supernatural ways God communicates with anyone who is willing to listen...are you one of them?