Download or read book Pulse Waves written by Paolo Salvi and published by Springer. This book was released on 2016-10-29 with total page 227 pages. Available in PDF, EPUB and Kindle. Book excerpt: This new, revised and updated edition takes into account the most recent advances in the understanding of human pathophysiology. The book presents the complex basic principles of vascular hemodynamics and its pathophysiologie in a direct and effective way, stressing the importance of the mechanical properties of large arteries in the origin of blood pressure. The readily understandable text, supported by helpful images, describes the elements that define blood pressure and explains such important concepts as pulse wave velocity, central blood pressure, reflected waves, and pulse pressure amplification. Entirely new chapters are included on the sympathetic nervous system and arterial stiffness and on the role played by arterial stiffness in influencing blood pressure variability. The book will enable the physician to answer some of the key questions encountered when addressing the problem of arterial hypertension in everyday clinical practice: How is blood pressure generated? How should blood pressure values be interpreted? Is systolic blood pressure of greater importance than diastolic blood pressure?
Download or read book Cardiovascular Hemodynamics for the Clinician written by George A. Stouffer and published by John Wiley & Sons. This book was released on 2017-03-06 with total page 390 pages. Available in PDF, EPUB and Kindle. Book excerpt: Cardiovascular Hemodynamics for the Clinician, 2nd Edition, provides a useful, succinct and understandable guide to the practical application of hemodynamics in clinical medicine for all trainees and clinicians in the field. Concise handbook to help both practicing and prospective clinicians better understand and interpret the hemodynamic data used to make specific diagnoses and monitor ongoing therapy Numerous pressure tracings throughout the book reinforce the text by demonstrating what will be seen in daily practice Topics include coronary artery disease; cardiomyopathies; valvular heart disease; arrhythmias; hemodynamic support devices and pericardial disease New chapters on TAVR, ventricular assist devices, and pulmonic valve disease, expanded coverage of pulmonary hypertension, fractional flow reserve, heart failure with preserved ejection fraction and valvular heart disease Provides a basic overview of circulatory physiology and cardiac function followed by detailed discussion of pathophysiological changes in various disease states
Download or read book Mechanisms of Vascular Disease written by Robert Fitridge and published by University of Adelaide Press. This book was released on 2011 with total page 589 pages. Available in PDF, EPUB and Kindle. Book excerpt: New updated edition first published with Cambridge University Press. This new edition includes 29 chapters on topics as diverse as pathophysiology of atherosclerosis, vascular haemodynamics, haemostasis, thrombophilia and post-amputation pain syndromes.
Download or read book Regulation of Tissue Oxygenation Second Edition written by Roland N. Pittman and published by Biota Publishing. This book was released on 2016-08-18 with total page 117 pages. Available in PDF, EPUB and Kindle. Book excerpt: This presentation describes various aspects of the regulation of tissue oxygenation, including the roles of the circulatory system, respiratory system, and blood, the carrier of oxygen within these components of the cardiorespiratory system. The respiratory system takes oxygen from the atmosphere and transports it by diffusion from the air in the alveoli to the blood flowing through the pulmonary capillaries. The cardiovascular system then moves the oxygenated blood from the heart to the microcirculation of the various organs by convection, where oxygen is released from hemoglobin in the red blood cells and moves to the parenchymal cells of each tissue by diffusion. Oxygen that has diffused into cells is then utilized in the mitochondria to produce adenosine triphosphate (ATP), the energy currency of all cells. The mitochondria are able to produce ATP until the oxygen tension or PO2 on the cell surface falls to a critical level of about 4–5 mm Hg. Thus, in order to meet the energetic needs of cells, it is important to maintain a continuous supply of oxygen to the mitochondria at or above the critical PO2 . In order to accomplish this desired outcome, the cardiorespiratory system, including the blood, must be capable of regulation to ensure survival of all tissues under a wide range of circumstances. The purpose of this presentation is to provide basic information about the operation and regulation of the cardiovascular and respiratory systems, as well as the properties of the blood and parenchymal cells, so that a fundamental understanding of the regulation of tissue oxygenation is achieved.
Download or read book Personalized Computational Hemodynamics written by Yuri Vassilevski and published by Academic Press. This book was released on 2020-04-19 with total page 282 pages. Available in PDF, EPUB and Kindle. Book excerpt: Personalized Computational Hemodynamics: Models, Methods, and Applications for Vascular Surgery and Antitumor Therapy offers practices and advances surrounding the multiscale modeling of hemodynamics and their personalization with conventional clinical data. Focusing on three physiological disciplines, readers will learn how to derive a suitable mathematical model and personalize its parameters to account for pathologies and diseases. Written by leading experts, this book mirrors the top trends in mathematical modeling with clinical applications. In addition, the book features the major results of the "Research group in simulation of blood flow and vascular pathologies" at the Institute of Numerical Mathematics of the Russian Academy of Sciences. Two important features distinguish this book from other monographs on numerical methods for biomedical applications. First, the variety of medical disciplines targeted by the mathematical modeling and computer simulations, including cardiology, vascular neurology and oncology. Second, for all mathematical models, the authors consider extensions and parameter tuning that account for vascular pathologies. Examines a variety of medical disciplines targeted by mathematical modeling and computer simulation Discusses how the results of numerical simulations are used to support clinical decision-making Covers hemodynamics relating to various subject areas, including vascular surgery and oncological tumor treatments
Download or read book The Cerebral Circulation written by Marilyn J. Cipolla and published by Biota Publishing. This book was released on 2016-07-28 with total page 82 pages. Available in PDF, EPUB and Kindle. Book excerpt: This e-book will review special features of the cerebral circulation and how they contribute to the physiology of the brain. It describes structural and functional properties of the cerebral circulation that are unique to the brain, an organ with high metabolic demands and the need for tight water and ion homeostasis. Autoregulation is pronounced in the brain, with myogenic, metabolic and neurogenic mechanisms contributing to maintain relatively constant blood flow during both increases and decreases in pressure. In addition, unlike peripheral organs where the majority of vascular resistance resides in small arteries and arterioles, large extracranial and intracranial arteries contribute significantly to vascular resistance in the brain. The prominent role of large arteries in cerebrovascular resistance helps maintain blood flow and protect downstream vessels during changes in perfusion pressure. The cerebral endothelium is also unique in that its barrier properties are in some way more like epithelium than endothelium in the periphery. The cerebral endothelium, known as the blood-brain barrier, has specialized tight junctions that do not allow ions to pass freely and has very low hydraulic conductivity and transcellular transport. This special configuration modifies Starling's forces in the brain microcirculation such that ions retained in the vascular lumen oppose water movement due to hydrostatic pressure. Tight water regulation is necessary in the brain because it has limited capacity for expansion within the skull. Increased intracranial pressure due to vasogenic edema can cause severe neurologic complications and death.
Download or read book Improving Assessments of Hemodynamics and Vascular Disease written by Magnus Ziegler and published by Linköping University Electronic Press. This book was released on 2019-04-24 with total page 64 pages. Available in PDF, EPUB and Kindle. Book excerpt: Blood vessels are more than simple pipes, passively enabling blood to pass through them. Their form and function are dynamic, changing with both aging and disease. This process involves a feedback loop wherein changes to the shape of a blood vessel affect the hemodynamics, causing yet more structural adaptation. This feedback loop is driven in part by the hemodynamic forces generated by the blood flow, and the distribution and strength of these forces appear to play a role in the initiation, progression, severity, and the outcome of vascular diseases. Magnetic Resonance Imaging (MRI) offers a unique platform for investigating both the form and function of the vascular system. The form of the vascular system can be examined using MR-based angiography, to generate detailed geometric analyses, or through quantitative techniques for measuring the composition of the vessel wall and atherosclerotic plaques. To complement these analyses, 4D Flow MRI can be used to quantify the functional aspect of the vascular system, by generating a full time-resolved three-dimensional velocity field that represents the blood flow. This thesis aims to develop and evaluate new methods for assessing vascular disease using novel hemodynamic markers generated from 4D Flow MRI and quantitative MRI data towards the larger goal of a more comprehensive non-invasive examination oriented towards vascular disease. In Paper I, we developed and evaluated techniques to quantify flow stasis in abdominal aortic aneurysms to measure this under-explored aspect of aneurysmal hemodynamics. In Paper II, the distribution and intensity of turbulence in the aorta was quantified in both younger and older men to understand how aging changes this aspect of hemodynamics. A method to quantify the stresses generated by turbulence that act on the vessel wall was developed and evaluated using simulated flow data in Paper III, and in Paper V this method was utilized to examine the wall stresses of the carotid artery. The hemodynamics of vascular disease cannot be uncoupled from the anatomical changes the vessel wall undergoes, and therefore Paper IV developed and evaluated a semi-automatic method for quantifying several aspects of vessel wall composition. These developments, taken together, help generate more valuable information from imaging data, and can be pooled together with other methods to form a more comprehensive non-invasive examination for vascular disease.
Download or read book Cardiovascular Hemodynamics written by Arman T. Askari and published by Springer. This book was released on 2019-07-12 with total page 403 pages. Available in PDF, EPUB and Kindle. Book excerpt: The second edition of this key resource provides a broad and fundamental overview of basic cardiovascular (CV) hemodynamic principles with a focus on clinical assessment of CV physiology. Extensively updated, the book includes new coverage on noninvasive hemodynamic assessment and the effects of selected interventions on CV hemodynamics. It provides an introduction to the basic concepts such as preload, afterload, myocardial contractility, and cardiac output. Subsequent chapters examine the effects of interventions such as vasodilators, beta blockers, pressor agents, inotropes, and different forms of invasive circulatory support. The book also focuses on various methods of hemodynamic evaluation including echocardiography, CT/MRI, noninvasive hemodynamic assessment, and cardiac catheterization. The book concludes with a discussion of proper diagnosis, evaluation, and management of patients using hemodynamic data on a variety of specific disease states. An invaluable contribution to the Contemporary Cardiology Series, the Second Edition of Cardiovascular Hemodynamics: An Introductory Guide is an essential resource for physicians, residents, fellows, medical students, and researchers in cardiology, emergency medicine, critical care, and internal medicine.
Download or read book Regulation of Coronary Blood Flow written by Michitoshi Inoue and published by Springer Science & Business Media. This book was released on 2013-11-09 with total page 330 pages. Available in PDF, EPUB and Kindle. Book excerpt: Research centering on blood flow in the heart continues to hold an important position, especially since a better understanding of the subject may help reduce the incidence of coronary arterial disease and heart attacks. This book summarizes recent advances in the field; it is the product of fruitful cooperation among international scientists who met in Japan in May, 1990 to discuss the regulation of coronary blood flow.
Download or read book Vascular Hemodynamics written by Peter J. Yim and published by Wiley-Blackwell. This book was released on 2008-10-06 with total page 0 pages. Available in PDF, EPUB and Kindle. Book excerpt: The only complete work on vascular hemodynamics Recently, vascular hemodynamics has undergone major advances, resulting from increasingly sophisticated imaging, computational, and clinical research methodologies. The effects of these advances are likely to be profound at both the scientific and clinical levels. Now, Vascular Hemodynamics provides a self-contained treatment of this rapidly advancing topic as it relates to vascular disease and related pathologies in the human body. Utilizing a multidisciplinary approach encompassing engineering, vascular biology, vascular imaging, and clinical practice, the book provides a survey of the basic science and clinical research in hemodynamics of the vasculature. The topics presented involve sophisticated modeling, imaging, and measurement techniques. The text emphasizes both the technical and clinical aspects of the field. Additionally, Vascular Hemodynamics: * Includes a wide variety of models of vascular pathology, including physical models, finite-element models, linear-system models, transmission-line models, and dye-dilution models * Discusses diverse pathologies of the large vessels, the microvasculature, and the systematic vasculature * Brings together a range of imaging modalities related to hemodynamics * Includes both introductory-level and research-oriented material on each topic Vascular Hemodynamics is the only single-text treatment of this important topic, making it a vital reference for researchers and students of bioengineering, radiology, vascular surgery, neurology, nephrology, cardiology, and oncology.
Download or read book Textbook of Clinical Hemodynamics written by Michael Ragosta and published by Elsevier Health Sciences. This book was released on 2008-01-01 with total page 264 pages. Available in PDF, EPUB and Kindle. Book excerpt: Here's a source of guidance on the analysis of the hemodynamic waveforms generated in the cardiac catheterization lab. It progresses from a review of basic monitoring principles and normal waveforms through an assessment of the waveform data associated with the full range of individual coronary diseases, providing the assistance needed to accurately interpret any findings encountered in practice. Its extremely clinically oriented approach makes it an ideal hands-on tool for any clinician involved in diagnosing cardiac problems using interventional cardiology.
Download or read book ABC of Hypertension written by D. Gareth Beevers and published by John Wiley & Sons. This book was released on 2010-07-15 with total page 89 pages. Available in PDF, EPUB and Kindle. Book excerpt: Hypertension is a condition which affects millions of peopleworldwide and its treatment greatly reduces the risk of strokes andheart attacks. This fully revised and updated edition of the ABCof Hypertension is an established guide providing all thenon-specialist needs to know about the measurement of bloodpressure and the investigation and management of hypertensivepatients. This new edition provides comprehensively updated andrevised information on how and whom to treat. The ABC of Hypertension will prove invaluable to generalpractitioners who may be screening large numbers of patients forhypertension, as well as nurse practitioners, midwives and otherhealthcare professionals.
Download or read book Dynamics Of The Vascular System Interaction With The Heart Second Edition written by Li John K-j and published by World Scientific. This book was released on 2018-09-05 with total page 296 pages. Available in PDF, EPUB and Kindle. Book excerpt: The first edition of the book was written employing mathematical techniques to formulate the physical principles involved in the structural and functional correlates of the underlying physiology.This current and self-contained second edition updates many of the new findings since its first edition a decade ago. It also includes a new chapter on the 'Interaction with the Heart'. The dynamics of the arterial system, the venous system, the microcirculation and their interaction with the heart are quantitatively described in terms of their structures and functions. Clinical measurements, applications to the cardiovascular field and physiological mechanisms are clearly identified throughout the text. Most importantly, worked examples are provided, such that the readers can appreciate the application aspects of the underlying formulation.
Download or read book Snapshots of Hemodynamics written by Nico Westerhof and published by Springer Science & Business Media. This book was released on 2006-01-12 with total page 182 pages. Available in PDF, EPUB and Kindle. Book excerpt: Hemodynamics makes it possible to characterize in a quantitative way, the function of the heart and arterial system, thereby producing information about what genetic and molecular processes are of importance for cardiovascular function. Snapshots of Hemodynamics: An Aid for Clinical Research and Graduate Education by Nico Westerhof, Nikos Stergiopulos and Mark I. M. Noble is a quick reference guide designed to help basic and clinical researchers as well as graduate students to understand hemodynamics. The layout of the book provides short and independent chapters that provide teaching diagrams as well as clear descriptions of the essentials of basic and applied principles of hemodynamics. References are provided at the end of each chapter for further reading and reference.
Download or read book Textbook of Arterial Stiffness and Pulsatile Hemodynamics in Health and Disease written by Julio A. Chirinos and published by Academic Press. This book was released on 2022-03-28 with total page 1036 pages. Available in PDF, EPUB and Kindle. Book excerpt: Textbook of Arterial Stiffness and Pulsatile Hemodynamics in Health and Disease, Two Volume Set covers the principles, physiology, biologic pathways, clinical implications and therapeutics surrounding arterial stiffness and pulsatile hemodynamics, along with a thorough overview of the field. The book presents complex engineering concepts in a way that those in science and medicine can more easily understand. It includes detailed illustrations. Additionally, it presents advanced bioengineering concepts in boxes for readers who wants more in-depth biophysical knowledge. This is a must-have reference for students, researchers and clinicians interested in learning more about this field. Incorporates case studies and calculations/worked examples with mathematical principles explained in a conceptual manner without complicated formulas Features chapter contributions from leading international researchers and clinicians Covers principles, physiology, biologic pathways, clinical implications and therapeutics
Download or read book Computational Hemodynamics Theory Modelling and Applications written by Jiyuan Tu and published by Springer. This book was released on 2015-02-24 with total page 360 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book discusses geometric and mathematical models that can be used to study fluid and structural mechanics in the cardiovascular system. Where traditional research methodologies in the human cardiovascular system are challenging due to its invasive nature, several recent advances in medical imaging and computational fluid and solid mechanics modelling now provide new and exciting research opportunities. This emerging field of study is multi-disciplinary, involving numerical methods, computational science, fluid and structural mechanics, and biomedical engineering. Certainly any new student or researcher in this field may feel overwhelmed by the wide range of disciplines that need to be understood. This unique book is one of the first to bring together knowledge from multiple disciplines, providing a starting point to each of the individual disciplines involved, attempting to ease the steep learning curve. This book presents elementary knowledge on the physiology of the cardiovascular system; basic knowledge and techniques on reconstructing geometric models from medical imaging; mathematics that describe fluid and structural mechanics, and corresponding numerical/computational methods to solve its equations and problems. Many practical examples and case studies are presented to reinforce best practice guidelines for setting high quality computational models and simulations. These examples contain a large number of images for visualization, to explain cardiovascular physiological functions and disease. The reader is then exposed to some of the latest research activities through a summary of breakthrough research models, findings, and techniques. The book’s approach is aimed at students and researchers entering this field from engineering, applied mathematics, biotechnology or medicine, wishing to engage in this emerging and exciting field of computational hemodynamics modelling.
Download or read book Snapshots of Hemodynamics written by Nicolaas Westerhof and published by Springer Science & Business Media. This book was released on 2010-09-02 with total page 263 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book is written in a quick reference style to help clinical and basic researchers, as well as graduate students, in the understanding of hemodynamics. Recent dev- opments in genetics and molecular biology on the one hand, and new noninvasive measurement techniques on the other hand, make it possible to measure and und- stand the hemodynamics of heart and vessels better than ever before. Hemodynamics makes it possible to characterize, in a quantitative way, and even with noninvasive techniques the function of the heart and the arterial system, separately and in c- bination, thereby producing information about what genetic and molecular processes are of importance for cardiovascular function. We have made the layout of the book such that it gives a succinct overview of individual topics in short chapters Therefore every chapter starts with a “box” c- taining a figure and caption, describing the main aspects of the subject. It is often sufficient to study the contents of this box alone to obtain this basic information, and therefore it is not necessary to read the book from cover to cover.