Download or read book Vaccination Against Mycobacterial Diseases in Animals written by John P. Bannantine and published by Frontiers Media SA. This book was released on 2015-05-06 with total page 95 pages. Available in PDF, EPUB and Kindle. Book excerpt: The two most prominent mycobacterial diseases in animals include bovine tuberculosis, caused by Mycobacterium bovis and Johne’s disease, caused by Mycobacterium avium subspecies paratuberculosis. Erradication of both diseases has been hampered by a variety of factors. In many countries, the persistence of tuberculosis in cattle has been attributed to reservoirs of M. bovis in wildlife species. Brushtail possums, deer and badgers are notable examples of wildlife reservoirs for M. bovis. The difficulties in eliminating the wildlife reservoir for M. bovis further suggest the need for vaccination of farmed livestock. Vaccination of wildlife species has also been attempted with mixed results. Delivery of the vaccine to wildlife species appears to be a chief obstacle. Vaccination itself leads to complications for diagnostics. For example, when cattle are vaccinated with both BCG and a commercial Johne’s vaccine there is a biased toward the avian tuberculin skin test reaction. Despite these issues, BCG seems to be the clear standard for vaccination against M. bovis, yet many laboratories are investigating ways to improve on BCG. For Johne’s disease, the available commercial vaccines consist of whole-cell preparations in one form or another. But with the ability to generate directed knockouts of specific genes, a number of defined mutants have been constructed in a few laboratories. These should be tested and directly compared with each other and alongside commercial vaccine formulations to determine not only which vaccine is most protective, but which animal model is best for predicting protection in the target host. To this end, there has been a nation-wide, multi-institutional effort to test the best live, attenuated vaccine against Johne's disease in cattle, sheep and goats. This vaccine trial has spanned six years and was conducted in three phases. The first phase examined attenuation in bovine macrophages, the second phase was colonization of spleen and liver in mice and the third phase was protection from bacterial challenge in goats. Many new ideas and retrospective approaches have emerged from this unprecedented effort. These aspects will be captured in this Research Topic. In this Research Topic, we will seek articles on these above topics, but other issues surrounding vaccination of animals against mycobacteria will also be explored. These include immune parameters, correlates of protection, adjuvants and other vaccine formulations, etc.

Download or read book Buruli Ulcer written by Gerd Pluschke and published by Springer. This book was released on 2019-04-29 with total page 290 pages. Available in PDF, EPUB and Kindle. Book excerpt: A major objective of this open access book is to summarize the current status of Buruli Ulcer (BU) research for the first time. It will identify gaps in our knowledge, stimulate research and support control of the disease by providing insight into approaches for surveillance, diagnosis, and treatment of Buruli Ulcer. Book chapters will cover the history, epidemiology diagnosis, treatment and disease burden of BU and provide insight into the microbiology, genomics, transmission and virulence of Mycobacterium ulcerans.

Download or read book Genomics and Biotechnological Advances in Veterinary Poultry and Fisheries written by Yashpal Singh Malik and published by Academic Press. This book was released on 2019-09-14 with total page 565 pages. Available in PDF, EPUB and Kindle. Book excerpt: Genomics and Biotechnological Advances in Veterinary, Poultry, and Fisheries is a comprehensive reference for animal biotechnologists, veterinary clinicians, fishery scientists, and anyone who needs to understand the latest advances in the field of next generation sequencing and genomic editing in animals and fish. This essential reference provides information on genomics and the advanced technologies used to enhance the production and management of farm and pet animals, commercial and non-commercial birds, and aquatic animals used for food and research purposes. This resource will help the animal biotechnology research community understand the latest knowledge and trends in this field. - Presents biological applications of cattle, poultry, marine and animal pathogen genomics - Discusses the relevance of biomarkers to improve farm animals and fishery - Includes recent approaches in cloning and transgenic cattle, poultry and fish production

Download or read book Mycobacterium bovis Infection in Animals and Humans written by Charles O. Thoen and published by John Wiley & Sons. This book was released on 2008-02-28 with total page 356 pages. Available in PDF, EPUB and Kindle. Book excerpt: Written by tuberculosis specialists from around the world, Mycobacterium Bovis Infection in Animals and Humans, Second Edition remains the most comprehensive collection of timely information regarding Mycobacterium bovis in any single source. The chapters are organized for quick access to well-indexed topics, and extensive reference lists are included to aid infectious disease specialists, regulatory officials, diagnosticians, researchers or public health workers interested in M bovis. This international reference includes the most current information on mechanisms of virulence of tubercle bacilli and immunologic and biochemical responses of the host involved in resistance. The book includes information on the diagnosis and application of the latest molecular techniques in epidemiologic investigations. Included are chapters on the economic impact of outbreaks of M. bovis in alternate species on control programs in domestic animals. There are also contributions by representatives of the International Union Against Tuberculosis and Lung Disease, PAHO of the World Health Organization, The Centers for Disease Control, and The University of Texas Health Center. This excellent reference is an invaluable aid to clinicians dealing directly with tuberculosis, as well as to government regulatory personnel, professional and graduate students, and instructors in basic and allied health sciences

Download or read book Disease Control Priorities Third Edition Volume 6 written by King K. Holmes and published by World Bank Publications. This book was released on 2017-11-06 with total page 1027 pages. Available in PDF, EPUB and Kindle. Book excerpt: Infectious diseases are the leading cause of death globally, particularly among children and young adults. The spread of new pathogens and the threat of antimicrobial resistance pose particular challenges in combating these diseases. Major Infectious Diseases identifies feasible, cost-effective packages of interventions and strategies across delivery platforms to prevent and treat HIV/AIDS, other sexually transmitted infections, tuberculosis, malaria, adult febrile illness, viral hepatitis, and neglected tropical diseases. The volume emphasizes the need to effectively address emerging antimicrobial resistance, strengthen health systems, and increase access to care. The attainable goals are to reduce incidence, develop innovative approaches, and optimize existing tools in resource-constrained settings.

Download or read book Zoonotic Tuberculosis written by Charles O. Thoen and published by John Wiley & Sons. This book was released on 2014-02-12 with total page 463 pages. Available in PDF, EPUB and Kindle. Book excerpt: Zoonotic Tuberculosis: Mycobacterium bovis and Other Pathogenic Mycobacteria, Third Edition is a comprehensive review of the state of the art in the control and elimination of infections caused by Mycobacterium tuberculosis complex in animals and humans. This update to the most complete and current reference available on Mycobacterium bovis includes new coverage of the latest molecular techniques; more information on human infection and One Health; updates to the information on the International Union Against Tuberculosis and Lung Disease (IUATLD), the World Health Organization (WHO), Pan American Health Organization (PAHO), and the United States Department of Agriculture’s (USDA) National Tuberculosis Eradication Program; and coverage of additional African countries. The Third Edition upholds the book’s reputation as a truly global resource on M. bovis. Written by an international list of tuberculosis experts, chapters cover the status of tuberculosis in many regions throughout the world and deal with issues related to the detection, spread, and control of Mycobacterium bovis, as well as the economic impact of outbreaks. Zoonotic Tuberculosis: Mycobacterium bovis and Other Pathogenic Mycobacteria offers valuable information for public health officials, medical doctors, state and federal regulatory veterinarians, veterinary practitioners, and animal caretakers.

Download or read book Tuberculosis Leprosy and Mycobacterial Diseases of Man and Animals written by Harshini Mukundan and published by CABI. This book was released on 2015-09-28 with total page 589 pages. Available in PDF, EPUB and Kindle. Book excerpt: Mycobacteria are bacterial pathogens which cause diseases in humans and non-human animals. This monograph will primarily cover the most important and widely researched groups of mycobacteria: members of the Mycobacterium tuberculosis complex (MTC) and Mycobacterium leprae, across a wide range of host species. M. tuberculosis and M. bovis are particularly relevant with the increasing drug resistance and co-infection with HIV associated with M. tuberculosis and the possible cross-infection of badgers and cattle associated with M. bovis. This book will provide a reference for researchers working in different fields creating a work which draws together information on different pathogens, and by considering the diseases in a zoonotic context provides a One Health approach to these important groups of diseases.

Download or read book Mycoplasmas in Swine written by Dominiek Maes and published by CABI. This book was released on 2021-03-12 with total page 346 pages. Available in PDF, EPUB and Kindle. Book excerpt: Swine can be infected with many different mycoplasmas. Some are important pathogens, causing significant health and welfare issues in pigs and major losses to the swine industry worldwide. Other mycoplasmas are not pathogenic for swine and can be considered commensals. This book provides up-to-date scientific, clinical and practical information of the most important pathogenic mycoplasmas in swine. Most emphasis has been placed on Mycoplasma hyopneumoniae as the most economically important, but other pathogenic species like Mycoplasma hyorhinis, Mycoplasma hyosynoviae and Mycoplasma suis are also discussed. Written by internationally renowned scientists and clinicians from all over the world, this book draws together in depth knowledge, expertise and experience in swine mycoplasmas to provide an evidence-based, academically rigorous and practical collection. It aims to serve the scientific and veterinary community and the swine industry worldwide.

Download or read book Heterologous Immunity Implications and Applications in Vaccines and Immunotherapies written by Babita Agrawal and published by Frontiers Media SA. This book was released on 2020-08-27 with total page 168 pages. Available in PDF, EPUB and Kindle. Book excerpt:

Download or read book Tuberculosis written by Wellman Ribón and published by BoD – Books on Demand. This book was released on 2015-07-08 with total page 242 pages. Available in PDF, EPUB and Kindle. Book excerpt: Progress obtained by mycobacteriology in recent years is undeniable with regards to preventing, detecting, and treating cases of tuberculosis, millennial disease that is still present as public health issue worldwide. We present here high-impact research and interest topics related to the application of new methodologies, especially molecular methods for rapid diagnostic such as rapid DST, application of high performance liquid chromatography, molecular epidemiology and molecular diagnostic testing on post mortem. Currently, the constant search for vaccines that prevent the disease is promising through research of the immune response generated by the host towards the bacterium, and the effectiveness that may be achieved from developed vaccines. Another high-impact factor is the one generated by considering tuberculosis as a social disease with an infectious component reflected in research about tuberculosis and human rights. Finally, we present important issues of the pathogen interaction with different hosts. The constant knowledge generation that expands the frontiers of understanding is a key factor for finding solutions and successful activities for public health.

Download or read book Diagnosis and Control of Johne s Disease written by National Research Council and published by National Academies Press. This book was released on 2003-08-13 with total page 243 pages. Available in PDF, EPUB and Kindle. Book excerpt: Johne's Disease is a chronic, progressive intestinal disease caused by infection with Mycobacterium avium subspecies paratuberculosis (Map) that affects primarily ruminant animals. In recent decades there has been growing concern over the lack of effective control of this disease and questions have arisen regarding the possibility that Map infection could be a cause of some cases of Crohn's disease in humans. This report presents a broad outline of the steps that should be taken to control Johne's disease, reduce the spread of Map, and minimize effects of the disease in animals. The report also describes the weaknesses of our current research agenda and provides recommendations for a new research strategy to resolve the question of whether there is a link between Johne's and Crohn's diseases.

Download or read book Tuberculosis written by Barry R. Bloom and published by . This book was released on 1994 with total page 664 pages. Available in PDF, EPUB and Kindle. Book excerpt: The authors discuss fundamental questions about the biology, genetics, mechanisms of pathogenicity, mechanisms of resistance, and drug development strategies that are likely to provide important new knowledge about TB and new interventions to prevent and treat this disease.

Download or read book Mucosal Vaccines written by Hiroshi Kiyono and published by Elsevier. This book was released on 1996-10-23 with total page 501 pages. Available in PDF, EPUB and Kindle. Book excerpt: This comprehensive, authoritative treatise covers all aspects of mucosal vaccines including their development, mechanisms of action, molecular/cellular aspects, and practical applications. The contributing authors and editors of this one-of-a-kind book are very well known in their respective fields. Mucosal Vaccines is organized in a unique format in which basic, clinical, and practical aspects of the mucosal immune system for vaccine development are described and discussed. This project is endorsed by the Society for Mucosal Immunology. - Provides the latest views on mucosal vaccines - Applies basic principles to the development of new vaccines - Links basic, clinical, and practical aspects of mucosal vaccines to different infectious diseases - Unique and user-friendly organization

Download or read book Malaria written by Institute of Medicine and published by National Academies Press. This book was released on 1991-02-01 with total page 312 pages. Available in PDF, EPUB and Kindle. Book excerpt: Malaria is making a dramatic comeback in the world. The disease is the foremost health challenge in Africa south of the Sahara, and people traveling to malarious areas are at increased risk of malaria-related sickness and death. This book examines the prospects for bringing malaria under control, with specific recommendations for U.S. policy, directions for research and program funding, and appropriate roles for federal and international agencies and the medical and public health communities. The volume reports on the current status of malaria research, prevention, and control efforts worldwide. The authors present study results and commentary on the: Nature, clinical manifestations, diagnosis, and epidemiology of malaria. Biology of the malaria parasite and its vector. Prospects for developing malaria vaccines and improved treatments. Economic, social, and behavioral factors in malaria control.

Download or read book Essential Tuberculosis written by Giovanni Battista Migliori and published by Springer Nature. This book was released on 2021-07-26 with total page 416 pages. Available in PDF, EPUB and Kindle. Book excerpt: This textbook covers the full spectrum of tuberculosis-related topics in a comprehensive yet easy-to-follow, readily accessible format. Filling a significant gap in tuberculosis literature, it addresses tuberculosis sensu latu, mirroring the content of the London Queen Mary University tuberculosis Diploma. Covering all aspects related to this condition, from prevention, diagnosis and treatment to public and global health, the book provides a broad overview of tuberculosis management. Further, it includes a wealth of case studies and exercises, making it an essential guide for all staff involved in tuberculosis management. Written by an international and interdisciplinary panel of experts, the book appeals to a broad readership including students, postdoctoral fellows, clinicians, researchers, and nurses, as well as public health officers working in tuberculosis control programs.

Download or read book Occupational Health and Safety in the Care and Use of Research Animals written by Committee on Occupational Safety and Health in Research Animal Facilities and published by National Academies Press. This book was released on 1997-06-23 with total page 167 pages. Available in PDF, EPUB and Kindle. Book excerpt: Much has been written about the care of research animals. Yet little guidance has appeared on protecting the health and safety of the people who care for or use these animals. This book, an implementation handbook and companion to Guide For the Care and Use of Laboratory Animals, identifies principles for building a program and discusses the accountability of institutional leaders, managers, and employees for a program's success. It provides a detailed description of risks-- physical and chemical hazards, allergens and zoonoses, and hazards from experiments--which will serve as a continuing reference for the laboratory. The book offers specific recommendations for controlling risk through administrative procedures, facility design, engineering controls, and periodic evaluations. The volume focuses on the worker, with detailed discussions of work practices, the use of personal protective gear, and the development of an emergency response plan. This handbook will be invaluable to administrators, researchers, and employees in any animal research facility. It will also be of interest to personnel in zoos, animal shelters, and veterinary facilities.

Download or read book Pathogenesis of Bacterial Infections in Animals written by Carlton L. Gyles and published by John Wiley & Sons. This book was released on 2011-06-09 with total page 674 pages. Available in PDF, EPUB and Kindle. Book excerpt: Pathogenesis of Bacterial Infections in Animals, Fourth Edition captures the rapid developments in understanding the mechanisms of virulence of the major bacterial pathogens of animals. Now including a color plate section, the book presents an overview of pathogenesis, including relevant events that occur in the herd or flock and its environment, and activities that take place at the cellular and molecular levels. With contributions from 64 experts in the field, this book serves as a great reference for graduate students in veterinary medicine and animal science, microbiologists, virologists and pathologists.