Download or read book The Demades Papyrus P Berol inv 13045 written by Davide Amendola and published by Walter de Gruyter GmbH & Co KG. This book was released on 2022-10-03 with total page 765 pages. Available in PDF, EPUB and Kindle. Book excerpt: Despite the significance of its contents, the so-called Demades papyrus (P.Berol. inv. 13045) has received scarce scholarly attention since the 1923 editio princeps by Karl Kunst. This unique late second-century BCE document of almost 430 lines was found in the Egyptian chora, but it is supposed to have been written in Alexandria, where it probably served as a textbook for the highest level of rhetorical education. Besides shedding new light on its find circumstances and physical aspects, the volume offers a full re-edition and commentary of the two adespota texts contained in it, namely a eulogy of the Lagid monarchy and a historical work consisting of a dialogue between Demades and his prosecutor in the trial of 319 BCE at the court of Pella. The aim of the accompanying introduction is to address the question of the origin, nature and purpose of such fragments and of the collection itself, as well as to show to what extent the papyrus contributes to a better understanding of some of the main historical events of the early Hellenistic period. This book is thus meant to fill a significant gap in Classical scholarship, all the more so as a close investigation of most of the topics dealt with therein has hitherto been lacking.
Download or read book New Drug Development for Known and Emerging Viruses written by Helga Rübsamen-Schaeff and published by John Wiley & Sons. This book was released on 2021-11-30 with total page 530 pages. Available in PDF, EPUB and Kindle. Book excerpt: Discusses how to fight Ebola, SARS Corona, and other known or emerging human viruses by building on the successes in antiviral therapy of the past decades Written by leading medicinal chemists from academia and industry, this book discusses the entire field of antiviral drug discovery and development from a medicinal chemistry perspective, focusing on antiviral drugs, targets, and viral disease mechanisms. It provides an outlook on emerging pathogens such as Ebola, Zika, West Nile, Lassa, and includes a chapter on SARS Coronoavirus-2 causing the present pandemic. New Drug Development for Known and Emerging Viruses describes the discovery and development process for antiviral agents for different classes of viruses and targets based on the experiences from the nine human viruses for which approved drugs are on the market (HIV, HCV, Influenza, RSV, HBV, HPV, HCMV, HSV, and VZV). It covers the properties and potential of 20 classes of currently approved antivirals, including combination drugs, and looks at novel antiviral strategies against emerging viruses. Covers the entire field of antiviral drug discovery and development Addresses the need for antiviral drugs to combat major health threats such as Ebola, Zika, West Nile, and SARS Coronavirus-2 Summarizes the successes of the past 15 years in developing ground-breaking medicines against 9 major human viruses, both from the medicinal chemistry and the pharmacological angle Discusses practical and strategic challenges in the drug discovery and development process, including screening technologies, latency, and toxicity issues New Developments in Antiviral Drugs is an important book for medicinal chemists, pharmaceutical chemists, virologists, and epidemiologists, and will be of great interest to those in the ;pharmaceutical industry and public health agencies.
Download or read book Burden of Proof written by John G. Hemry and published by Penguin. This book was released on 2004-02-24 with total page 304 pages. Available in PDF, EPUB and Kindle. Book excerpt: In John G. Hemry's terrific military science fiction series, a young officer risks everything in his fight for justice . . . Lieutenant Junior Grade Paul Sinclair must adjust to his new position on the warship USS Michaelson--juggling his Legal Officer responsibilities and his personal life, as his relationship with girlfriend Jen Shen intensifies. When an explosion takes out most of Forward Engineering, Sinclair leads the effort to extinguish the fire. He's practically a hero. But when Captain Shen, Jen’s father, is brought in to conduct an investigation, it seems that he’s gunning for his daughter’s suitor. Soon Sinclair uncovers evidence that points to a cover-up—involving a rising star in the officer corps. His evidence is circumstantial, and the suspect is the son of a powerful vice admiral. Sinclair is determined to see justice done, but is he willing to risk his name, his career, and his future among the stars?
Download or read book The Routledge Handbook of Social Studies of Outer Space written by Juan Francisco Salazar and published by Taylor & Francis. This book was released on 2023-07-10 with total page 778 pages. Available in PDF, EPUB and Kindle. Book excerpt: The Routledge Handbook of Social Studies of Outer Space offers state-of-the-art overview of contemporary social and cultural research on outer space. International in scope, the thirty-eight contributions by over fifty leading researchers and artists across a variety of disciplines and fields of knowledge, present a range of debates and pose key questions about the crafting of futures in relation to outer space. The Handbook is a call to attend more carefully to engagements with outer space, empirically, affectively, and theoretically, while characterizing current research practices and outlining future research agendas. This recalibration opens profound questions of intersectional politics, race, equity, and environmental justice around the contested topics of space exploration and life off-Earth. Among the many themes included in the volume are the various infrastructures, networks and systems that enable and sustain space exploration; space heritage; the ethics of outer space; social and environmental justice; fundamental debates about life in outer space as it pertains to both astrobiology and SETI; the study of scientific communities; the human body and consciousness; Indigenous astronomical systems of Knowledge; contemporary space art; and ongoing critical interventions to overcome the legacies of colonialism and dismantle hegemonic narratives of outer space.
Download or read book A Wizard of Earthsea written by Ursula K. Le Guin and published by Houghton Mifflin Harcourt. This book was released on 2012 with total page 267 pages. Available in PDF, EPUB and Kindle. Book excerpt: Originally published in 1968, Ursula K. Le Guin's A Wizard of Earthsea marks the first of the six now beloved Earthsea titles. Ged was the greatest sorcerer in Earthsea, but in his youth he was the reckless Sparrowhawk. In his hunger for power and knowledge, he tampered with long-held secrets and loosed a terrible shadow upon the world. This is the tumultuous tale of his testing, how he mastered the mighty words of power, tamed an ancient dragon, and crossed death's threshold to restore the balance.
Download or read book Child 44 written by Tom Rob Smith and published by Simon and Schuster. This book was released on 2009-04-01 with total page 471 pages. Available in PDF, EPUB and Kindle. Book excerpt: DON'T MISS THE NEW TOM ROB SMITH NOVEL, COLD PEOPLE, OUT NOW! OVER 2 MILLION COPIES SOLD MOSCOW, 1953. Under Stalin’s terrifying regime, families live in fear. When the all-powerful State claims there is no such thing as crime, who dares disagree? AN INTERNATIONAL BESTSELLER IN OVER 30 LANGUAGES An ambitious secret police officer, Leo Demidov believes he’s helping to build the perfect society. But when he uncovers evidence of a killer at large – a threat the state won’t admit exists – Demidov must risk everything, including the lives of those he loves, in order to expose the truth. A THRILLER UNLIKE ANY YOU HAVE EVER READ But what if the danger isn’t from the killer he is trying to catch, but from the country he is fighting to protect? Nominated for seventeen international awards and inspired by a real-life investigation, CHILD 44 is a relentless story of love, hope and bravery in a totalitarian world. From the screenwriter of the acclaimed television series, THE ASSASSINATION OF GIANNI VERSACE: AMERICAN CRIME STORY.
Download or read book Self employment Tax written by and published by . This book was released on 1988 with total page 12 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Download or read book Steel s Edge written by Ilona Andrews and published by Penguin. This book was released on 2012-11-27 with total page 401 pages. Available in PDF, EPUB and Kindle. Book excerpt: The Edge lies between worlds, on the border between the Broken, where people shop at Wal-Mart and magic is a fairy tale—and the Weird, where blueblood aristocrats rule, changelings roam, and the strength of your magic can change your destiny… Charlotte de Ney is as noble as they come, a blueblood straight out of the Weird. But even though she possesses rare magical healing abilities, her life has brought her nothing but pain. After her marriage crumbles, she flees to the Edge to build a new home for herself. Until Richard Mar is brought to her for treatment, and Charlotte’s life is turned upside down once again. Richard is a swordsman without peer, future head of his large and rambunctious Edger clan—and he’s on a clandestine quest to wipe out slavers trafficking humans in the Weird. So when his presence leads his very dangerous enemies to Charlotte, she vows to help Richard destroy them. The slavers’ operation, however, goes deeper than Richard knows, and even working together, Charlotte and Richard may not survive...
Download or read book Taxpayer Advocate Service is Here to Help written by United States. Taxpayer Advocate Service and published by . This book was released on with total page 24 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Download or read book My Own Words written by Ruth Bader Ginsburg and published by Simon and Schuster. This book was released on 2016-10-04 with total page 400 pages. Available in PDF, EPUB and Kindle. Book excerpt: "The first book from Ruth Bader Ginsburg since becoming a Supreme Court Justice in 1993--a ... collection of writings and speeches from the woman who has had [an] ... influence on law, women's rights, and popular culture"--
Download or read book Urban Rage written by Mustafa Dikeç and published by Yale University Press. This book was released on 2017-01-01 with total page 275 pages. Available in PDF, EPUB and Kindle. Book excerpt: A timely and incisive examination of contemporary urban unrest that explains why riots will continue until citizens are equally treated and politically included In the past few decades, urban riots have erupted in democracies across the world. While high profile politicians often react by condemning protestors' actions and passing crackdown measures, urban studies professor Mustafa Dikeç shows how these revolts are in fact rooted in exclusions and genuine grievances which our democracies are failing to address. In this eye-opening study, he argues that global revolts may be sparked by a particular police or government action but nonetheless are expressions of much longer and deep seated rage accumulated through hardship and injustices that have become routine. Increasingly recognized as an expert on urban unrest, Dikeç examines urban revolts in the United States, United Kingdom, France, Sweden, Greece, and Turkey and, in a sweeping and engaging account, makes it clear that change is only possible if we address the failures of democratic systems and rethink the established practices of policing and political decision-making.
Download or read book Inter American Yearbook on Human Rights Anuario Interamericano de Derechos Humanos Volume 33 2017 written by Inter-American Commission on Human Rights and published by BRILL. This book was released on 2022-11-07 with total page 768 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Download or read book Supplemental Security Income State and County Data written by and published by . This book was released on 1985 with total page 158 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Download or read book Monooxygenase Peroxidase and Peroxygenase Properties and Mechanisms of Cytochrome P450 written by Eugene G. Hrycay and published by Springer. This book was released on 2015-05-22 with total page 376 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book describes in 13 chapters mechanisms of P450 used to monooxygenate substrates via the NAD(P)H/O2 pathway using its peroxidase and peroxygenase functions. P450 also utilizes peroxides, peracids, periodate and iodosobenzene to oxygenate substrates via the shunt pathway. Also described are mechanisms used in the oxidation of pharmaceuticals by CYP3A4; acyl- carbon cleavage by CYP17A1, CYP19A1 and CYP51A1; metabolism of tetrabromodiphenyl ethers and bile acids by CYP2B6 and CYP3A4; metabolism of ω-6 and ω-3 polyunsaturated fatty acids; H2O2-mediated peroxygenation of substrates using substrate misrecognition; P450 oxidative reactions using electrochemical methods; electron transfer to P450 by redox proteins; hydroxylation of 1,8-cineole by P450cin; and peroxygenation by unspecific peroxygenases using H2O2. The topics covered are relevant to P450 researchers, professors and students from a variety of disciplines ranging from pharmacology, toxicology and microbiology to chemistry.
Download or read book Canadian Film and Video written by Loren R. Lerner and published by University of Toronto Press. This book was released on 1997-01-01 with total page 1862 pages. Available in PDF, EPUB and Kindle. Book excerpt: This extensive bibliography and reference guide is an invaluable resource for researchers, practitioners, students, and anyone with an interest in Canadian film and video. With over 24,500 entries, of which 10,500 are annotated, it opens up the literature devoted to Canadian film and video, at last making it readily accessible to scholars and researchers. Drawing on both English and French sources, it identifies books, catalogues, government reports, theses, and periodical and newspaper articles from Canadian and non-Canadian publications from the first decade of the twentieth century to 1989. The work is bilingual; descriptive annotations are presented in the language(s) of the original publication. Canadian Film and Video / Film et vidéo canadiens provides an in-depth guide to the work of over 4000 individuals working in film and video and 5000 films and videos. The entries in Volume I cover topics such as film types, the role of government, laws and legislation, censorship, festivals and awards, production and distribution companies, education, cinema buildings, women and film, and video art. A major section covers filmmakers, video artists, cinematographers, actors, producers, and various other film people. Volume II presents an author index, a film and video title index, and a name and subject index. In the tradition of the highly acclaimed publication Art and Architecture in Canada these volumes fill a long-standing need for a comprehensive reference tool for Canadian film and video. This bibliography guides and supports the work of film historians and practitioners, media librarians and visual curators, students and researchers, and members of the general public with an interest in film and video.
Download or read book The Demades Papyrus P Berol Inv 13045 written by Davide Amendola and published by de Gruyter. This book was released on 2022-09-05 with total page 0 pages. Available in PDF, EPUB and Kindle. Book excerpt: "Sozomena" means "saved" in Greek. The series is dedicated to the recovery and presentation of texts that have only survived from Greek or Roman antiquity thanks to extraordinary find circumstances. It is primarily concerned with papyri, thousands of which await deciphering in universities and libraries. The primary intention of the series is to edit and interpret texts, but methods of recovery and presentation will also be discussed, so that different types of books will be published: editions of texts, commentaries, monographs and collections. The main language is English, together with German and Italian.
Download or read book Breast Cancer Metastasis and Drug Resistance written by Aamir Ahmad and published by Springer Nature. This book was released on 2019-08-27 with total page 432 pages. Available in PDF, EPUB and Kindle. Book excerpt: Resistance to therapies, both targeted and systemic, and metastases to distant organs are the underlying causes of breast cancer-associated mortality. The second edition of Breast Cancer Metastasis and Drug Resistance brings together some of the leading experts to comprehensively understand breast cancer: the factors that make it lethal, and current research and clinical progress. This volume covers the following core topics: basic understanding of breast cancer (statistics, epidemiology, racial disparity and heterogeneity), metastasis and drug resistance (bone metastasis, trastuzumab resistance, tamoxifen resistance and novel therapeutic targets, including non-coding RNAs, inflammatory cytokines, cancer stem cells, ubiquitin ligases, tumor microenvironment and signaling pathways such as TRAIL, JAK-STAT and mTOR) and recent developments in the field (epigenetic regulation, microRNAs-mediated regulation, novel therapies and the clinically relevant 3D models). Experts also discuss the advances in laboratory research along with their translational and clinical implications with an overarching goal to improve the diagnosis and prognosis, particularly that of breast cancer patients with advanced disease.
