Download or read book Tutorials in Mathematical Biosciences IV written by Avner Friedman and published by Springer. This book was released on 2008-04-26 with total page 215 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book offers an introduction to fast growing research areas in evolution of species, population genetics, ecological models, and population dynamics. It reviews the concept and methodologies of phylogenetic trees, introduces ecological models, examines a broad range of ongoing research in population dynamics, and deals with gene frequencies under the action of migration and selection. The book features computational schemes, illustrations, and mathematical theorems.
Download or read book Tutorials in Mathematical Biosciences II written by James Sneyd and published by Springer Science & Business Media. This book was released on 2005-06-22 with total page 228 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book presents a series of models in the general area of cell physiology and signal transduction, with particular attention being paid to intracellular calcium dynamics, and the role played by calcium in a variety of cell types. Calcium plays a crucial role in cell physiology, and the study of its dynamics lends insight into many different cellular processes. In particular, calcium plays a central role in muscular contraction, olfactory transduction and synaptic communication, three of the topics to be addressed in detail in this book. In addition to the models, much of the underlying physiology is presented, so that readers may learn both the mathematics and the physiology, and see how the models are applied to specific biological questions. It is intended primarily as a graduate text or a research reference. It will serve as a concise and up-to-date introduction to all those who wish to learn about the state of calcium dynamics modeling, and how such models are applied to physiological questions.
Download or read book Tutorials in Mathematical Biosciences III written by Avner Friedman and published by Springer Science & Business Media. This book was released on 2005-12-19 with total page 260 pages. Available in PDF, EPUB and Kindle. Book excerpt: This volume introduces some basic mathematical models for cell cycle, proliferation, cancer, and cancer therapy. Chapter 1 gives an overview of the modeling of the cell division cycle. Chapter 2 describes how tumor secretes growth factors to form new blood vessels in its vicinity, which provide it with nutrients it needs in order to grow. Chapter 3 explores the process that enables the tumor to invade the neighboring tissue. Chapter 4 models the interaction between a tumor and the immune system. Chapter 5 is concerned with chemotherapy; it uses concepts from control theory to minimize obstacles arising from drug resistance and from cell cycle dynamics. Finally, Chapter 6 reviews mathematical results for various cancer models.
Download or read book Tutorials in Mathematical Biosciences I written by Alla Borisyuk and published by Springer Science & Business Media. This book was released on 2005-02-18 with total page 184 pages. Available in PDF, EPUB and Kindle. Book excerpt: This volume introduces some basic theories on computational neuroscience. Chapter 1 is a brief introduction to neurons, tailored to the subsequent chapters. Chapter 2 is a self-contained introduction to dynamical systems and bifurcation theory, oriented towards neuronal dynamics. The theory is illustrated with a model of Parkinson's disease. Chapter 3 reviews the theory of coupled neural oscillators observed throughout the nervous systems at all levels; it describes how oscillations arise, what pattern they take, and how they depend on excitory or inhibitory synaptic connections. Chapter 4 specializes to one particular neuronal system, namely, the auditory system. It includes a self-contained introduction, from the anatomy and physiology of the inner ear to the neuronal network that connects the hair cells to the cortex, and describes various models of subsystems.
Download or read book Tutorials in Mathematical Biosciences written by and published by . This book was released on 2008 with total page 236 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Download or read book Mathematical Modeling in Systems Biology written by Brian P. Ingalls and published by MIT Press. This book was released on 2022-06-07 with total page 423 pages. Available in PDF, EPUB and Kindle. Book excerpt: An introduction to the mathematical concepts and techniques needed for the construction and analysis of models in molecular systems biology. Systems techniques are integral to current research in molecular cell biology, and system-level investigations are often accompanied by mathematical models. These models serve as working hypotheses: they help us to understand and predict the behavior of complex systems. This book offers an introduction to mathematical concepts and techniques needed for the construction and interpretation of models in molecular systems biology. It is accessible to upper-level undergraduate or graduate students in life science or engineering who have some familiarity with calculus, and will be a useful reference for researchers at all levels. The first four chapters cover the basics of mathematical modeling in molecular systems biology. The last four chapters address specific biological domains, treating modeling of metabolic networks, of signal transduction pathways, of gene regulatory networks, and of electrophysiology and neuronal action potentials. Chapters 3–8 end with optional sections that address more specialized modeling topics. Exercises, solvable with pen-and-paper calculations, appear throughout the text to encourage interaction with the mathematical techniques. More involved end-of-chapter problem sets require computational software. Appendixes provide a review of basic concepts of molecular biology, additional mathematical background material, and tutorials for two computational software packages (XPPAUT and MATLAB) that can be used for model simulation and analysis.
Download or read book Tutorials in Mathematical Biosciences written by and published by . This book was released on 2005 with total page pages. Available in PDF, EPUB and Kindle. Book excerpt:
Download or read book Tutorials in mathematical biosciences written by and published by . This book was released on with total page pages. Available in PDF, EPUB and Kindle. Book excerpt:
Download or read book Nonlinear Optimization written by Immanuel M. Bomze and published by Springer. This book was released on 2010-03-17 with total page 301 pages. Available in PDF, EPUB and Kindle. Book excerpt: This volume collects the expanded notes of four series of lectures given on the occasion of the CIME course on Nonlinear Optimization held in Cetraro, Italy, from July 1 to 7, 2007. The Nonlinear Optimization problem of main concern here is the problem n of determining a vector of decision variables x ? R that minimizes (ma- n mizes) an objective function f(·): R ? R,when x is restricted to belong n to some feasible setF? R , usually described by a set of equality and - n n m equality constraints: F = {x ? R : h(x)=0,h(·): R ? R ; g(x) ? 0, n p g(·): R ? R }; of course it is intended that at least one of the functions f,h,g is nonlinear. Although the problem canbe stated in verysimpleterms, its solution may result very di?cult due to the analytical properties of the functions involved and/or to the number n,m,p of variables and constraints. On the other hand, the problem has been recognized to be of main relevance in engineering, economics, and other applied sciences, so that a great lot of e?ort has been devoted to develop methods and algorithms able to solve the problem even in its more di?cult and large instances. The lectures have been given by eminent scholars, who contributed to a great extent to the development of Nonlinear Optimization theory, methods and algorithms. Namely, they are: – Professor Immanuel M.
Download or read book Nonlinear and Optimal Control Theory written by and published by Springer Science & Business Media. This book was released on 2008 with total page 368 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Download or read book Layer Adapted Meshes for Reaction Convection Diffusion Problems written by Torsten Linß and published by Springer. This book was released on 2009-11-21 with total page 331 pages. Available in PDF, EPUB and Kindle. Book excerpt: This is a book on numerical methods for singular perturbation problems – in part- ular, stationary reaction-convection-diffusion problems exhibiting layer behaviour. More precisely, it is devoted to the construction and analysis of layer-adapted meshes underlying these numerical methods. Numerical methods for singularly perturbed differential equations have been studied since the early 1970s and the research frontier has been constantly - panding since. A comprehensive exposition of the state of the art in the analysis of numerical methods for singular perturbation problems is [141] which was p- lished in 2008. As that monograph covers a big variety of numerical methods, it only contains a rather short introduction to layer-adapted meshes, while the present book is exclusively dedicated to that subject. An early important contribution towards the optimisation of numerical methods by means of special meshes was made by N.S. Bakhvalov [18] in 1969. His paper spawned a lively discussion in the literature with a number of further meshes - ing proposed and applied to various singular perturbation problems. However, in the mid 1980s, this development stalled, but was enlivened again by G.I. Shishkin’s proposal of piecewise-equidistant meshes in the early 1990s [121,150]. Because of their very simple structure, they are often much easier to analyse than other meshes, although they give numerical approximations that are inferior to solutions on c- peting meshes. Shishkin meshes for numerous problems and numerical methods have been studied since and they are still very much in vogue.
Download or read book Algebraic Groups and Lie Groups with Few Factors written by Alfonso Di Bartolo and published by Springer Science & Business Media. This book was released on 2008-04-17 with total page 223 pages. Available in PDF, EPUB and Kindle. Book excerpt: This volume treats algebraic groups from a group theoretical point of view and compares the results with the analogous issues in the theory of Lie groups. It examines a classification of algebraic groups and Lie groups having only few subgroups.
Download or read book Tutorials in Mathematical Biosciences III written by Avner Friedman and published by Springer. This book was released on 2005-11-23 with total page 254 pages. Available in PDF, EPUB and Kindle. Book excerpt: This volume introduces some basic mathematical models for cell cycle, proliferation, cancer, and cancer therapy. Chapter 1 gives an overview of the modeling of the cell division cycle. Chapter 2 describes how tumor secretes growth factors to form new blood vessels in its vicinity, which provide it with nutrients it needs in order to grow. Chapter 3 explores the process that enables the tumor to invade the neighboring tissue. Chapter 4 models the interaction between a tumor and the immune system. Chapter 5 is concerned with chemotherapy; it uses concepts from control theory to minimize obstacles arising from drug resistance and from cell cycle dynamics. Finally, Chapter 6 reviews mathematical results for various cancer models.
Download or read book Geometric Description of Images as Topographic Maps written by Vicent Caselles and published by Springer. This book was released on 2009-12-24 with total page 200 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book discusses the basic geometric contents of an image and presents a treedatastructuretohandleite?ciently.Itanalyzesalsosomemorphological operators that simplify this geometric contents and their implementation in termsofthe datastructuresintroduced.It?nallyreviewsseveralapplications to image comparison and registration, to edge and corner computation, and the selection of features associated to a given scale in images. Let us ?rst say that, to avoid a long list, we shall not give references in this summary; they are obviously contained in this monograph. A gray level image is usually modeled as a function de?ned in a bounded N domain D? R (typically N = 2 for usual snapshots, N=3formedical images or movies) with values in R. The sensors of a camera or a CCD array transform the continuum of light energies to a ?nite interval of values by means of a nonlinear function g. The contrast change g depends on the pr- ertiesofthesensors,butalsoontheilluminationconditionsandthere?ection propertiesofthe objects,andthoseconditionsaregenerallyunknown.Images are thus observed modulo an arbitrary and unknown contrast change.
Download or read book Blow up Theories for Semilinear Parabolic Equations written by Bei Hu and published by Springer. This book was released on 2011-03-17 with total page 137 pages. Available in PDF, EPUB and Kindle. Book excerpt: There is an enormous amount of work in the literature about the blow-up behavior of evolution equations. It is our intention to introduce the theory by emphasizing the methods while seeking to avoid massive technical computations. To reach this goal, we use the simplest equation to illustrate the methods; these methods very often apply to more general equations.
Download or read book The Art of Random Walks written by Andras Telcs and published by Springer. This book was released on 2006-10-18 with total page 193 pages. Available in PDF, EPUB and Kindle. Book excerpt: The main aim of this book is to reveal connections between the physical and geometric properties of space and diffusion. This is done in the context of random walks in the absence of algebraic structure, local or global spatial symmetry or self-similarity. The author studies heat diffusion at this general level and discusses the multiplicative Einstein relation; Isoperimetric inequalities; and Heat kernel estimates; Elliptic and parabolic Harnack inequality.
Download or read book Smooth Ergodic Theory for Endomorphisms written by Min Qian and published by Springer. This book was released on 2009-07-07 with total page 292 pages. Available in PDF, EPUB and Kindle. Book excerpt: Ideal for researchers and graduate students, this volume sets out a general smooth ergodic theory for deterministic dynamical systems generated by non-invertible endomorphisms. Its focus is on the relations between entropy, Lyapunov exponents and dimensions.
