Download or read book tude des changes gazeux nocturnes chez les enfants atteints de Trisomie 21 written by Nicolas Richard and published by . This book was released on 2018 with total page 0 pages. Available in PDF, EPUB and Kindle. Book excerpt: Introduction : La Trisomie 21 est l'anomalie chromosomique la plus fréquente chez les nouveau-nés. Ces enfants ont un risque élevé de développer un syndrome d'apnées obstructives du sommeil (SAOS), parfois associé à une hypoventilation alvéolaire importante. L'objectif principal de cette étude est de comparer les échanges gazeux nocturnes (Pression transcutanée en dioxyde de carbone ou PtcCO2 et Saturation pulsée en oxygène ou SpO2) d'enfants atteints de Trisomie 21 à ceux d'un groupe témoin. Patients et méthodes : Etude rétrospective monocentrique de type cas témoins portant sur les polysomnographies (PSG) d'enfants atteints ou non de Trisomie 21. Les dossiers cliniques des patients ont également été étudiés afin de rechercher des signes cliniques de SAOS et des comorbidités associées à la Trisomie 21. Les cas et les témoins étaient appariés sur 2 paramètres : l'index d'apnées hypopnées (IAH) et l'âge. Résultats : 28 enfants atteints de Trisomie 21 ont été inclus dans cette étude, puis appariés à 28 témoins ayant bénéficié d'une PSG pour un SAOS clinique. La PtcCO2 moyenne au sommeil était significativement plus élevée dans le groupe Trisomie 21 comparé au groupe témoin (44.7 mmHg vs 42.4 mmHg, p = 0.0089), ainsi que le pourcentage de temps de sommeil passé avec une PtcCO2 supérieure à 50 mmHg (9.1 vs 1.4, p = 0.011). La SpO2 moyenne au sommeil était significativement diminuée par rapport au groupe témoin (95.7% vs 96.3%, p = 0.048). Discussion : Cette étude est la 1ère étude comparant les échanges gazeux d'enfants atteints de Trisomie 21 et ceux d'enfants non syndromiques, présentant ou non un SAOS à la PSG. Elle montre notamment que les enfants atteints de Trisomie 21 ont une PtcCO2 plus élevée, indépendamment du degré de sévérité d'un éventuel SAOS (mesuré par l'IAH). Les 2 hypothèses que nous formulons ici pour expliquer ces résultats sont la présence d'une hypotonie des muscles respiratoires et/ou l'existence d'une dysfonction du système nerveux autonome et donc de la commande ventilatoire. Perspectives : Une étude prospective serait intéressante afin de confirmer ces résultats. Elle permettrait également de rechercher chez les enfants atteints de Trisomie 21 es signes d'hypotonie et de dysautonomie ; et un éventuel retentissement neuropsychologique d'une hypoventilation alvéolaire.

Download or read book Cambridge Yearbook of European Legal Studies Vol 13 2010 2011 written by Catherine Barnard and published by Bloomsbury Publishing. This book was released on 2011-12-15 with total page 337 pages. Available in PDF, EPUB and Kindle. Book excerpt: The Cambridge Yearbook of European Legal Studies provides a forum for the scrutiny of significant issues in EU Law, the law of the European Convention on Human Rights, and Comparative Law with a 'European' dimension, and particularly those issues which have come to the fore during the year preceding publication. The contributions appearing in the collection are commissioned by the Centre for European Legal Studies (CELS) Cambridge, a research centre in the Law Faculty of the University of Cambridge specialising in European legal issues. The papers presented are at the cutting edge of the fields which they address, and reflect the views of recognised experts drawn from the University world, legal practice, and the institutions of both the EU and its Member States. Inclusion of the comparative dimension brings a fresh perspective to the study of European law, and highlights the effects of globalisation of the law more generally, and the resulting cross fertilisation of norms and ideas that has occurred among previously sovereign and separate legal orders. The Cambridge Yearbook of European Legal Studies is an invaluable resource for those wishing to keep pace with legal developments in the fast moving world of European integration. INDIVIDUAL CHAPTERS Please click on the link below to purchase individual chapters from Volume 13 through Ingenta Connect: www.ingentaconnect.com SUBSCRIPTION TO SERIES To place an annual online subscription or a print standing order through Hart Publishing please click on the link below. Please note that any customers who have a standing order for the printed volumes will now be entitled to free online access. www.hartjournals.co.uk/cyels/subs Editorial Advisory Board: Albertina Albors-Llorens, John Bell, Alan Dashwood, Simon Deakin, David Feldman, Richard Fentiman, Angus Johnston, John Spencer Founding Editors: Alan Dashwood and Angela Ward Ius Commune Prize 2012 Alexandre Saydé wrote Chapter 15 in this volume entitled: 'One Law, Two Competitions: An Enquiry into the Contradictions of Free Movement Law' and we are delighted to announce that he has been awarded the Ius Commune Prize 2012.

Download or read book Socialism Perestroika and the Dilemmas of Soviet Economic Reform written by John E Tedstrom and published by Routledge. This book was released on 2021-12-13 with total page 239 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book highlights that Soviet economic planners and politicians must come to recognize the need to make fundamental changes, not simply incremental refinements, in the failing Soviet system. It examines the dynamics of the process of perestroika and the complexity of individual economic issues.

Download or read book Notes on the Minor Prophets written by Henry Allan Ironside and published by . This book was released on 1955 with total page 464 pages. Available in PDF, EPUB and Kindle. Book excerpt:

Download or read book The Ladybird Illustrated written by D H Lawrence and published by . This book was released on 2020-11-09 with total page 100 pages. Available in PDF, EPUB and Kindle. Book excerpt: "The Ladybird is a long tale or novella by D. H. Lawrence. It was first drafted in 1915 as a short story entitled The Thimble. Lawrence rewrote and extended it under a new title in December 1921 and sent the final version to his English agent on 9 January 1922. It was collected with two other tales, The Captain's Doll and The Fox, and the three novellas were then published in London by Martin Secker in March 1923 under the title The Ladybird and in New York by Thomas Seltzer as The Captain's Doll in April 1923."