Download or read book Toxicology of the Gastrointestinal Tract written by Shayne Cox Gad and published by CRC Press. This book was released on 2007-01-23 with total page 378 pages. Available in PDF, EPUB and Kindle. Book excerpt: Toxicology of the Gastrointestinal Tract focuses on the specifics of the mechanisms and adverse effects of xenobiotic agents and pharmaceuticals on the structure and function of the GI tract. The book focuses on a number of specific areas of intestinal research. Beginning with the well-recognized and major functions of nutrient absorption and its r
Download or read book Toxicology of the Gastrointestinal Tract Second Edition written by Shayne Cox Gad and published by CRC Press. This book was released on 2018-10-26 with total page 477 pages. Available in PDF, EPUB and Kindle. Book excerpt: Nanoparticles as both potential unique risks and as a valuable approach to increased and higher specificity in delivery of therapeutics A primer on the largest, most diverse, and important microbiome in any mammal "Tricks of the trade" on modifying the oral administration of drugs
Download or read book Gastrointestinal Toxicology written by Karl Rozman and published by Elsevier Publishing Company. This book was released on 1986 with total page 640 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Download or read book Comprehensive Toxicology Volume 9 written by R.S. McCuskey and published by Pergamon. This book was released on 1999-08-04 with total page 0 pages. Available in PDF, EPUB and Kindle. Book excerpt: This volume, which is separated into two parts, presents important new information concerning mechanisms of effect and consequences of exposure of the liver and gastrointestinal tract to a wide variety of toxicants. Both sections on the liver and GI tract provide the reader with concise introductory descriptions of relevant cellular and organ anatomy, physiology, and mechanisms of toxic injury. Specific consideration is given to methods of toxin exposure and to processes that provide defence against injury. The discussions provide a broad focus but also contain details about molecular, cellular, and biochemical mechanisms. The section on the liver (34 chapters) provides a comprehensive review of the toxic effects of a wide variety of specific compounds including volatile hydrocarbons, anesthetic agents, drugs of therapeutic value as well as of abuse, heavy metals, natural compounds etc. The section on the gastrointestinal tract (15 chapters), presenting toxicology of the esophagus, stomach, small intestine, and colon, represents the first major reference work available that provides both a broad overview of the effect of toxicants on the mucosal, motility, and immune functions of the GI tract as well as specific information about specific toxicants. The final chapter presents an overview of clinical toxicology in animals with specific focus on the liver and gastrointestinal systems. This volume is of specific interest and use to those concerned with environmental and industrial toxicology, as well as with mechanisms of toxicant injury and clinical medicine.
Download or read book Comprehensive Toxicology written by and published by Elsevier. This book was released on 2010-06-01 with total page 6448 pages. Available in PDF, EPUB and Kindle. Book excerpt: An explosive increase in the knowledge of the effects of chemical and physical agents on biological systems has led to an increased understanding of normal cellular functions and the consequences of their perturbations. The 14-volume Second Edition of Comprehensive Toxicology has been revised and updated to reflect new advances in toxicology research, including content by some of the leading researchers in the field. It remains the premier resource for toxicologists in academia, medicine, and corporations. Comprehensive Toxicology Second Edition provides a unique organ-systems structure that allows the user to explore the toxic effects of various substances on each human system, aiding in providing diagnoses and proving essential in situations where the toxic substance is unknown but its effects on a system are obvious. Comprehensive Toxicology Second Edition is the most complete and valuable toxicology work available to researchers today. Contents updated and revised to reflect developments in toxicology research Organized with a unique organ-system approach Features full color throughout Available electronically on sciencedirect.com, as well as in a limited-edition print version
Download or read book Comprehensive Toxicology Volume 9 written by R.S. McCuskey and published by Pergamon. This book was released on 1999-08-18 with total page 750 pages. Available in PDF, EPUB and Kindle. Book excerpt: This volume, which is separated into two parts, presents important new information concerning mechanisms of effect and consequences of exposure of the liver and gastrointestinal tract to a wide variety of toxicants. Both sections on the liver and GI tract provide the reader with concise introductory descriptions of relevant cellular and organ anatomy, physiology, and mechanisms of toxic injury. Specific consideration is given to methods of toxin exposure and to processes that provide defence against injury. The discussions provide a broad focus but also contain details about molecular, cellular, and biochemical mechanisms. The section on the liver (34 chapters) provides a comprehensive review of the toxic effects of a wide variety of specific compounds including volatile hydrocarbons, anesthetic agents, drugs of therapeutic value as well as of abuse, heavy metals, natural compounds etc. The section on the gastrointestinal tract (15 chapters), presenting toxicology of the esophagus, stomach, small intestine, and colon, represents the first major reference work available that provides both a broad overview of the effect of toxicants on the mucosal, motility, and immune functions of the GI tract as well as specific information about specific toxicants. The final chapter presents an overview of clinical toxicology in animals with specific focus on the liver and gastrointestinal systems. This volume is of specific interest and use to those concerned with environmental and industrial toxicology, as well as with mechanisms of toxicant injury and clinical medicine.
Download or read book Gastrointestinal Pharmacology written by Beverley Greenwood-Van Meerveld and published by Springer. This book was released on 2017-04-19 with total page 444 pages. Available in PDF, EPUB and Kindle. Book excerpt: This volume aims to connect current ideas and concepts about GI disorders with the search for novel therapeutics. Towards this goal, authors provide a timely state-of-the-art overview of the GI tract in health and disease, current treatment approaches and ongoing developments in drug discovery, and their potential for the better treatment of patients with GI disorders.
Download or read book Role of gut bacteria in human toxicology and pharmacology written by Bradley Hillman and published by CRC Press. This book was released on 1995-04-27 with total page 286 pages. Available in PDF, EPUB and Kindle. Book excerpt: An examination of the composition and metabolic activity of microorganisms commonly found in the human gut. Chapters cover the effects gut flora have on ingested compounds, vitamin production and gastrointestinal disorders. Comparisons are also made between microbial and mammalian metabolism.
Download or read book Intestinal Toxicology written by Carol M. Schiller and published by . This book was released on 1984 with total page 264 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Download or read book Biological Toxins and Bioterrorism written by P. Gopalakrishnakone and published by Springer. This book was released on 2015-01-22 with total page 0 pages. Available in PDF, EPUB and Kindle. Book excerpt: Biological toxins are an important part of our world, a reality with which we need to cope, so in parallel with understanding their mechanisms of action and thereby improving our fundamental knowledge, there are successful efforts to utilize them as therapeutics against some debilitating human and animal diseases. In view of the complexity of different types of biotoxins and the broad range of toxin structure, physiology, utility, and countermeasures including regulatory issues, it was thus aimed to compile a book on biotoxins and bioweapons. This reference work in the Toxinology handbook series gathers together knowledge from around the globe about naturally inspired and manufactured biological weapons. The authors describe how they work; how authorities may detect their presence, prevent their use, and diagnose their impacts; and the means by which medical and paramedical professionals may treat victims. Also described are how they have been used to further our knowledge and what insights they have given us into evolutionary and physiological processes. Finally, it is also discussed how these toxins can be used as therapeutics and what the implications of such therapeutics are to their use as biothreat agents. This volume provides a reference accessible to scientists, educators, and medical experts alike with an interest in biotoxins, focusing on the major toxins used as bioweapons. Regulatory agencies will also benefit from the information provided in this book. Some in the intended audience may need to understand how they elicit their effects and how we can defend ourselves against them. Others may be interested in the sometimes colorful histories that surround this subset of biotoxins that can be and, in some cases, have been used as weapons.
Download or read book Introduction to Basics of Pharmacology and Toxicology written by Abialbon Paul and published by Springer Nature. This book was released on 2021-03-13 with total page 1156 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book explains the pharmacological relationships between the various systems in the human body. It offers a comprehensive overview of the pharmacology concerning the autonomic, central, and peripheral nervous systems. Presenting up-to-date information on chemical mediators and their significance, it highlights the therapeutic aspects of several diseases affecting the cardiovascular, renal, respiratory, gastrointestinal, endocrinal, and hematopoietic systems. The book also includes drug therapy for microbial and neoplastic diseases. It also comprises sections on immunopharmacology, dermatological, and ocular pharmacology providing valuable insights into these emerging and recent topics. Covering the diverse groups of drugs acting on different systems, the book reviews their actions, clinical uses, adverse effects, interactions, and subcellular mechanisms of action. It is divided into 11 parts, subdivided into several chapters that evaluate the basic pharmacological principles that govern the different types of body systems. This book is intended for academicians, researchers, and clinicians in industry and academic institutions in pharmaceutical, pharmacological sciences, pharmacy, medical sciences, physiology, neurosciences, biochemistry, molecular biology and other allied health sciences.
Download or read book Fundamentals of Toxicologic Pathology written by Matthew A. Wallig and published by Academic Press. This book was released on 2009-11-23 with total page 714 pages. Available in PDF, EPUB and Kindle. Book excerpt: Toxicologic pathology integrates toxicology and the disciplines within it (such as biochemistry, pharmacodynamics and risk assessment) to pathology and its related disciplines (such as physiology, microbiology, immunology, and molecular biology). Fundamentals of Toxicologic Pathology Second Edition updates the information presented in the first edition, including five entirely new chapters addressing basic concepts in toxicologic pathology, along with color photomicrographs that show examples of specific toxicant-induced diseases in animals. The current edition also includes comparative information that will prove a valuable resource to practitioners, including diagnostic pathologists and toxicologists. 25% brand new information, fully revised throughout New chapters: Veterinary Diagnostic Toxicologic Pathology; Clinical Pathology; Nomenclature: Terminology for Morphologic Alterations; Techniques in Toxicologic Pathology New color photomicrographs detailing specific toxicant-induced diseases in animals Mechanistic information integrated from both toxicology and pathology discussing basic mechanisms of toxic injury and morphologic expression at the subcellular, cellular, and tissue levels
Download or read book Effects of Mycotoxins on the Intestine written by Isabelle P. Oswald and published by MDPI. This book was released on 2019-04-30 with total page 262 pages. Available in PDF, EPUB and Kindle. Book excerpt: Mycotoxins are secondary metabolites produced by several fungal species. They can contaminate human food and animal feed, and have been a threat for thousands of years. The gastrointestinal tract is the first target when ingesting mycotoxin-contaminated food or feed. As unlikely as it sounds, the investigations concerning the effects of mycotoxins on the intestine are still in their early stages. This book gathers the most recent advances related to the characterization of the intestinal toxicity of mycotoxins. Substantial data assembled on the damage caused to a number of histological structures and functions of the intestine remove any remaining doubt about this organ being a primary target for the toxicity of mycotoxins. An interesting overview of the detrimental effects of mycotoxins on the gut-hosted microbiota—now regarded as a fully-fledged organ associated with the gut—is also given. Finally, outstanding contributions in this book address questions relating to the suitability of current regulations to protect against alterations of the intestine, and to the efficacy assessment of new detoxification strategies using the intestinal toxicity of mycotoxins as a relevant endpoint.
Download or read book Toxicology of the Gastrointestinal Tract Second Edition written by Shayne Cox Gad and published by CRC Press. This book was released on 2018-10-26 with total page 321 pages. Available in PDF, EPUB and Kindle. Book excerpt: The gastrointestinal tract is the most important of the three major routes of entry (and clearance) of xenobiotics and biologic entities into the bodies of mammals. As such, it is also the major route for administration of pharmaceuticals to humans. Gastrointestinal Toxicology, Second Edition describes the mechanism for entry and clearance of xenobiotics, as well as the barriers, immunologic and metabolic issues, and functions present in the GI tract. Appearing in this volume are also considerations of the microbiome and its actions and influence on the function of the GI tract and on the toxicity and pharmacodynamics of ingested substances (including nutrients, toxins, and therapeutics). These fifteen chapters written by experienced experts in the field address methods to evaluate GI function; specifics of GI function and toxicity assessment in canines and minipigs; classes of compounds with their toxicity; species differences; and the toxicity (and promise) of nanoparticles. Those needing to understand the structure, function, and methods of studying the GI tract will find this volume a singular source of reference.
Download or read book Principles of Safety Pharmacology written by Michael K. Pugsley and published by Springer. This book was released on 2015-06-19 with total page 477 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book illustrates, in a comprehensive manner, the most current areas of importance to Safety Pharmacology, a burgeoning unique pharmacological discipline with important ties to academia, industry and regulatory authorities. It provides readers with a definitive collection of topics containing essential information on the latest industry guidelines and overviews current and breakthrough topics in both functional and molecular pharmacology. An additional novelty of the book is that it constitutes academic, pharmaceutical and biotechnology perspectives for Safety Pharmacology issues. Each chapter is written by an expert in the area and includes not only a fundamental background regarding the topic but also detailed descriptions of currently accepted, validated models and methods as well as innovative methodologies used in drug discovery.
Download or read book Alcohol and the Gastrointestinal Tract written by Victor R. Preedy and published by CRC Press. This book was released on 1996 with total page 376 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book covers all aspects of gastrointestinal tract problems caused by alcohol misuse. Opening chapters discuss epidemiology and the metabolism of alcohol and the liver's role in that process. Alcohol and acetaldehyde dehydrogenases, free radicals, and endocrine changes are discussed in detail. Recent advances in the pathophysiology of alcohol-induced disorders are summarized and many chapters detail techniques such as permeability and protein synthesis. Effects on specific organs, including the salivary glands, stomach, pancreas, and small intestine, are also discussed. All contributors and both editors are internationally recognized experts in their fields.
Download or read book Toxicity Of Pure Foods written by E. M. Boyd and published by CRC Press. This book was released on 2020-04-19 with total page 431 pages. Available in PDF, EPUB and Kindle. Book excerpt: First Published in 1973, this book offers a full, comprehensive guide into the toxicology of certain foods. Carefully compiled and filled with a vast repertoire of notes, diagrams, and references this book serves as a useful reference for students of toxicology, and other practitioners in their respective fields.
