Download or read book Toxicology for Nontoxicologists written by Mark E. Stelljes and published by Rowman & Littlefield. This book was released on 2008 with total page 218 pages. Available in PDF, EPUB and Kindle. Book excerpt: Providing non-scientific readers with basic toxicological concepts, this updated edition of Toxicology for Non-Toxicologists explains how those concepts and their applications affect everyday life. Readers will find an introduction to the study of toxic chemicals on humans and the environment, close examinations of toxicology issues, and a discussion of the general approach to risk assessment.
Download or read book Toxicology for Non Toxicologists written by and published by . This book was released on 2007 with total page 218 pages. Available in PDF, EPUB and Kindle. Book excerpt: Providing non-scientific readers with basic toxicological concepts, this updated edition of Toxicology for Non-Toxicologists explains how those concepts and their applications affect everyday life. Readers will find an introduction to the study of toxic chemicals on humans and the environment, close examinations of toxicology issues, and a discussion of the general approach to risk assessment.
Download or read book Toxicology for Non Toxicologists written by Mark E. Stelljes and published by Government Institutes. This book was released on 2007-11-26 with total page 218 pages. Available in PDF, EPUB and Kindle. Book excerpt: Toxicology for Non-Toxicologists provides non-scientific readers with basic toxicological concepts and explains how those concepts and their applications affect everyday life. It is designed for professionals in the environmental field as well as for a more general audience. Completely updated, this edition includes new overviews of key emerging issues, including nanotechnology, endocrine disruptors, and vapor intrusion of chemicals in indoor air. It also includes a new case study, tracking how a new chemical comes to market, and a brief summary of the types of jobs toxicologists have and the types of work that they do. Readers will find an introduction to the study of toxic chemicals on humans and the environment, including discussions on organic foods, food additives, and pesticides; pollution incidents in both the air and the water; misleading media reporting of toxicology; and the limitations of current toxicology knowledge. It also focuses on key concepts in toxicology, examines four types of toxic effects, and discusses the regulatory framework of environmental laws and federal organizations as they pertain to toxicology.
Download or read book A Comprehensive Guide to Toxicology in Nonclinical Drug Development written by Ali S. Faqi and published by Academic Press. This book was released on 2016-11-03 with total page 986 pages. Available in PDF, EPUB and Kindle. Book excerpt: A Comprehensive Guide to Toxicology in Nonclinical Drug Development, Second Edition, is a valuable reference designed to provide a complete understanding of all aspects of nonclinical toxicology in the development of small molecules and biologics. This updated edition has been reorganized and expanded to include important topics such as stem cells in nonclinical toxicology, inhalation and dermal toxicology, pitfalls in drug development, biomarkers in toxicology, and more. Thoroughly updated to reflect the latest scientific advances and with increased coverage of international regulatory guidelines, this second edition is an essential and practical resource for all toxicologists involved in nonclinical testing in industry, academic, and regulatory settings. Provides unique content that is not always covered together in one comprehensive resource, including chapters on stem cells, abuse liability, biomarkers, inhalation toxicology, biostatistics, and more Updated with the latest international guidelines for nonclinical toxicology in both small and large molecules Incorporates practical examples in order to illustrate day-to-day activities and the expectations associated with working in nonclinical toxicology
Download or read book Pathology for Toxicologists written by Elizabeth McInnes and published by John Wiley & Sons. This book was released on 2017-05-01 with total page 210 pages. Available in PDF, EPUB and Kindle. Book excerpt: Non-pathologists, such as toxicologists and study personnel, can find it difficult to understand the data they receive from pathologists. Toxicological pathologists write long, detailed and highly technical reports. Study personnel are under daily pressure to decide whether lesions described in pathology reports are treatment-related and thus important to the pharmaceutical company or whether the lesions are background changes and thus of little significance. Written by experienced toxicological pathologists, Pathology for Toxicologists: Principles and Practices of Laboratory Animal Pathology for Study Personnel serves to bridge the gap in the understanding of pathology data, enabling non-pathologists to more easily comprehend pathology reports, better integrate pathology data into final study reports and ask pathologists relevant questions about the test compound. This succinct, fully referenced, full colour book is suitable for toxicologists at all stages of their training or career who want to know more about the pathology encountered in laboratory animals used in safety studies. Key features include important chapters on spontaneous and target organ lesions in rats, mice, non-human primates, mini pigs, rabbits and beagle dogs as well as information on general pathology, macroscopic target organ lesions, ancillary pathology techniques, haematology, biochemistry and adversity. Pathology for Toxicologists: Principles and Practices of Laboratory Animal Pathology for Study Personnel includes: Colour diagrams explaining how lesions are caused by either external compounds or spontaneously The anatomic variations and background lesions of laboratory animals Advice on sampling tissues, necropsy, ancillary pathology techniques and recording data A chapter on the haematology and biochemistry of laboratory animals Full colour photographs of common macroscopic lesions encountered in laboratory animals A comprehensive glossary
Download or read book Information Resources in Toxicology written by P.J. Bert Hakkinen and published by Elsevier. This book was released on 2000-01-10 with total page 953 pages. Available in PDF, EPUB and Kindle. Book excerpt: Information Resources in Toxicology, Third Edition is a sourcebook for anyone who needs to know where to find toxicology information. It provides an up-to-date selective guide to a large variety of sources--books, journals, organizations, audiovisuals, internet and electronic sources, and more. For the Third Edition, the editors have selected, organized, and updated the most relevant information available. New information on grants and other funding opportunities, physical hazards, patent literature, and technical reports have also been added.This comprehensive, time-saving tool is ideal for toxicologists, pharmacologists, drug companies, testing labs, libraries, poison control centers, physicians, legal and regulatory professionals, and chemists. Serves as an all-in-one resource for toxicology information New edition includes information on publishers, grants and other funding opportunities, physical hazards, patent literature, and technical reports Updated to include the latest internet and electronic sources, e-mail addresses, etc. Provides valuable data about the new fields that have emerged within toxicological research; namely, the biochemical, cellular, molecular, and genetic aspects
Download or read book Alternative Toxicological Methods written by Harry Salem and published by CRC Press. This book was released on 2003-03-26 with total page 616 pages. Available in PDF, EPUB and Kindle. Book excerpt: Bringing together the recent and relevant contributions of over 125 scientists from industry, government, and academia in North America and Western Europe, Alternative Toxicological Methods explores the development and validation of replacement, reduction, and refinement alternatives (the 3Rs) to animal testing. Internationally recognized scientist
Download or read book Toxicology A Primer on Toxicology Principles and Applications written by Michael A. Kamrin and published by CRC Press. This book was released on 1988-02-01 with total page 160 pages. Available in PDF, EPUB and Kindle. Book excerpt: Different from other books, this unique volume presents basic toxicology principles and applications in a sophisticated yet nontechnical style. It provides an understanding of both the strengths and limitations of the discipline of toxicology and its benefits. This primer is valuable for virtually any non-toxicologist.
Download or read book Concepts in Toxicology written by John H. Duffus and published by Royal Society of Chemistry. This book was released on 2009 with total page 189 pages. Available in PDF, EPUB and Kindle. Book excerpt: This is a reference for those who need to understand the fundamental toxicological concepts that underlie both the scientific development of the subject and its practical applicaton in regulation and management of chemical safety.
Download or read book Toxicology written by P. Gupta and published by . This book was released on 2018-05-30 with total page 547 pages. Available in PDF, EPUB and Kindle. Book excerpt: The book entitled "Toxicology" Resource for Self Study Questions is an essential and practical document for self-study and guidance catering to a broad spectrum of students. This book covers a range of core toxicological areas which is aimed to make the study of toxicology simple and understandable through key points, short-problem-solving and objective questions. The information is collated and prepared from standard and authoritative textbooks which are widely scanned. The author's own experience in different branches of toxicology has been abstracted in this book. This book covers a range of key points in several core toxicological areas, including general principle of toxicology, mechanism of toxicity, disposition of xenobiotics, toxicokinetics, target organ toxicity, non-target organ toxicity such as carcinogenicity, genotoxicity, developmental abnormalities, metals and micronutrients, pesticides and fertilizers, biotoxins and venomous organisms, poisonous foods and food poisonings, gases, solvents and vapors, toxic effect of plants, radioactive materials, environmental and eco-toxicology as well as forensic and clinical toxicology. Across 15 chapters, the book "Toxicology", presents key concepts supplemented with practical exercises to support active learning; these exercises include objective questions in the format of short-problem-solving questions (900), multiple choice questions (1200), fill in the blanks (750), true/false (250) and match of statements (200). These questions will help readers gain a deeper understanding of toxicology, as well as assist memory retention for university and board examinations. The main strength of the book is that it reflects the breadth and multidisciplinary nature of toxicology with objective approach to the subject and provides comprehensive coverage of key toxicological concepts for self-study and revision. For example, the student who needs a study aid for toxicology; the teacher of toxicology who needs inspiration when composing questions for their students; the established toxicologist who wants to test their knowledge or understanding, and for in-house training courses in toxicology which I know exist in some pharmaceutical and chemical industries. Thus, this book will be useful for toxicology, pharmacy, medical, and veterinary students, and serves as a refresher for academicians and professionals in the field, including clinical pharmacists, forensic toxicologists, environmentalists, and veterinarians.Toxicology is a rapidly evolving field. Suggestions and comments are welcome to help the author improve the contents of the book. Please also suggest the deficiencies need to be covered at [email protected] or [email protected], if you have any topics you feel should be better covered in any future editions.
Download or read book Pharmaceutical Toxicology in Practice written by Alberto Lodola and published by John Wiley & Sons. This book was released on 2011-03-31 with total page 280 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book describes, with references to key source materials, the background to, and conduct of, the principal nonclinical studies that are central to drug development. The chapters provide an understanding of the key components of the preclinical phase of drug development with a hands-on description, with core chapters addressing study conduct, types, and reporting. As such, it is a practical guide through toxicology testing and an up-to-date reference on current issues, new developments, and future directions in toxicology. Opening with a practical description of toxicology and its role in the development of pharmaceuticals, the book proceeds to detail international regulations (including the impact of the new REACH standards for chemical safety), interdisciplinary interactions among scientists in drug development, steps in toxicity testing, and risk management. Further, the book covers the methods of genetic toxicology (assays, genomics, in vivo screening) as a complement to “traditional” toxicology in the risk assessment and risk management of pharmaceuticals.
Download or read book Handbook of Toxicology Third Edition written by Michael J. Derelanko and published by CRC Press. This book was released on 2014-03-07 with total page 1027 pages. Available in PDF, EPUB and Kindle. Book excerpt: The Handbook of Toxicology, Third Edition provides an updated practical reference source for practicing toxicologists in the pharmaceutical and chemical industries, contract laboratories, regulatory agencies, and academia. Written by experts in their specific toxicology fields, the chapters provide both fundamental and applied information. Topics range from General Toxicology, to Genetic Toxicology, Human Clinical Toxicology, Histopathology, Clinical Pathology, Metabolism and Toxicokinetics, Risk Assessment, and more. New to this edition: Completely rewritten chapters covering immunotoxicology, endocrine toxicology, and reproductive and developmental toxicology, providing a fresh perspective on these topics Addition of new chapters on Chemical Toxicology, Pharmaceutical Toxicology, Juvenile Toxicology, and Safety Pharmacology Updated information dealing with Inhalation Toxicology, Neurotoxicology, and Regulatory Toxicology, which has been consolidated into single chapters for each specialty A separate glossary with toxicological terms presented both alphabetically and by toxicological subspecialty For nearly 20 years, this handbook has remained the only reference book of its kind, designed to facilitate easy access to information related to the various toxicology specialties. This updated edition of a popular reference book reflects current practices and the state of the science of toxicology.
Download or read book A Comprehensive Guide to Toxicology in Preclinical Drug Development written by Ali S. Faqi and published by Academic Press. This book was released on 2012-10-18 with total page 903 pages. Available in PDF, EPUB and Kindle. Book excerpt: A Comprehensive Guide to Toxicology in Preclinical Drug Development is a resource for toxicologists in industry and regulatory settings, as well as directors working in contract resource organizations, who need a thorough understanding of the drug development process. Incorporating real-life case studies and examples, the book is a practical guide that outlines day-to-day activities and experiences in preclinical toxicology. This multi-contributed reference provides a detailed picture of the complex and highly interrelated activities of preclinical toxicology in both small molecules and biologics. The book discusses discovery toxicology and the international guidelines for safety evaluation, and presents traditional and nontraditional toxicology models. Chapters cover development of vaccines, oncology drugs, botanic drugs, monoclonal antibodies, and more, as well as study development and personnel, the role of imaging in preclinical evaluation, and supporting materials for IND applications. By incorporating the latest research in this area and featuring practical scenarios, this reference is a complete and actionable guide to all aspects of preclinical drug testing. Chapters written by world-renowned contributors who are experts in their fields Includes the latest research in preclinical drug testing and international guidelines Covers preclinical toxicology in small molecules and biologics in one single source
Download or read book The Toxicologist s Pocket Handbook written by Michael J. Derelanko and published by CRC Press. This book was released on 2017-11-06 with total page 533 pages. Available in PDF, EPUB and Kindle. Book excerpt: The third edition of the Toxicologist’s Pocket Handbook, like the first two editions, is a scaled-down version of the best-selling Handbook of Toxicology. It provides the most frequently used toxicology reference information in a convenient pocket-sized book. The format remains the same as the earlier editions to allow basic reference information to be located quickly, with the information placed in sections specific to subspecialties of toxicology. A detailed table of contents lists all tables and figures contained in the book by section. This expanded edition contains a number of tables not found in the second edition added to sections on lab animals, general toxicology, dermal and ocular toxicology, genetic toxicology/carcinogenesis, neurotoxicology, immunotoxicology, reproductive/developmental toxicology, industrial chemical, and pharmaceutical toxicology. New information is presented for additional laboratory animals such as swine and primates, infusion recommendations, newer methods such as the local lymph node assay, and reference safety pharmacology values for standard species. Additional information on typical genetic toxicology and immunotoxicology assays as well as in vitro assays for eye irritation are provided. Some tables from the second edition have been updated to include new information that has arisen since the earlier edition went to press. Information from the second edition, such as regulatory requirements that are no longer applicable, has been deleted.
Download or read book Toxicologic Pathology for Non Pathologists written by Thomas J. Steinbach and published by Springer Nature. This book was released on 2019-10-31 with total page 919 pages. Available in PDF, EPUB and Kindle. Book excerpt: This extensive volume began as a short course primarily geared toward toxicologists who want to expand their understanding of toxicologic pathology in order to be better study directors while also proving to be of great interest to other drug development scientists and regulatory reviewers. The overall goal is to help non-pathologists understand, contextualize, and communicate the pathology data and interpretations from the study pathologist in a practical and usable format. Within the book, readers will find an overview of general pathology concepts that include fundamental vocabulary and the basics of pathophysiological processes, along with numerous chapters devoted to pathology in specific organ systems as well as topics such as biomarkers, correlation of clinical pathology endpoints (chemistry and hematology) with microscopic changes, and well-known pathology findings for classes of toxic substances. Authoritative, practical, and comprehensive, Toxicologic Pathology for Non-Pathologists aims to help non-pathologists understand, converse in, and apply a basic understanding of pathology in their day-to-day careers.
Download or read book Case Studies in Medical Toxicology written by Leslie R. Dye and published by Springer. This book was released on 2017-12-22 with total page 256 pages. Available in PDF, EPUB and Kindle. Book excerpt: The ACMT National Case Conference (NCC) is a monthly discussion of novel or interesting cases in medical toxicology. Participation is through online webinar, and the conferences are recorded to allow for review at any time. The cases in this book are taken from recordings of NCC with edits and revisions by contributors and editors to demonstrate educational points. The majority of the case information is from the original recording and represents actual patient presentations. However, some of the details have been changed and fictional information added to enhance the educational value. This volume covers a broad range of toxicological topics, and specialty guidance is offered at the end of every case to aid non-toxicologists. The dilemmas are applicable to both academic and clinical medicine. A list of relevant questions is also provided for each case. Subjects include common toxicological problems, rare presentations of common problems, common problems with controversial treatments or difficult diagnoses, and rare problems. Case Studies in Medical Toxicology from the American College of Medical Toxicology is a detailed reference text on specific toxicological issues and also serves as a practical review for those taking board exams. As a result, this volume is an important and necessary resource for medical students, residents, and fellows, as well as primary-care physicians, intensivists, and toxicologistsCase Studies in Medical Toxicology from the American College of Medical Toxicology is a detailed reference text on specific toxicological issues and also serves as a practical review for those taking board exams. As a result, this volume is an important and necessary resource for medical students, residents, and fellows, as well as primary-care physicians, intensivists, and toxicologists. All proceeds from this book will be donated to the Medical Toxicology Foundation.
Download or read book Molecular and Cellular Toxicology written by Lesley Stanley and published by John Wiley & Sons. This book was released on 2014-06-03 with total page 452 pages. Available in PDF, EPUB and Kindle. Book excerpt: Toxicology is the study of the adverse effects of chemical, physical, or biological agents on people, animals, and the environment. Toxicologists are trained to investigate, interpret, and communicate the nature of those effects. Over the last ten years the subject of toxicology has changed dramatically, moving from a discipline which was once firmly wedded to traditional methods to one which is keen to embrace the innovative techniques emerging from the developing fields of cell culture and molecular biology. There is an acute need for this to be reflected in a paradigm shift which takes advantage of the opportunities offered by modern developments in the life sciences, including new in vitro and in silico approaches, alternative whole organism (non-mammalian) models and the exploitation of ‘omics methods, high throughput screening (HTS) techniques and molecular imaging technologies. This concise, accessible introduction to the field includes the very latest concepts and methodologies. It provides MSc, PhD and final year undergraduate students in pharmacy, biomedical and life sciences, as well as individuals starting out in the cosmetics, consumer products, pharmaceutical and testing industries, with everything they need to know to get to grips with the fast moving field of toxicology and the current approaches used in the risk assessment of drugs and chemicals.
