Download or read book Toxic Interactions written by Robin S. Goldstein and published by Elsevier. This book was released on 2013-10-22 with total page 503 pages. Available in PDF, EPUB and Kindle. Book excerpt: Toxic Interactions is a collection of papers that discusses the basic principles behind the mechanism of toxicological interactions. This book deals with interacting chemicals and their effects on certain exposed organs or molecules. Concerning discussion of the principles, contributed papers explain the role of xenobiotic biotransformation processes in inactivating reactive intermediates of toxicants. Other authors discuss the effects of endogenous molecules and the consequences of chemically induced depletion of protective agents, as well as the pharmacokinetic principles that affect chemical interactions. Several authors also review experiments on the types of chemicals that produce or increase the degree of toxicity. The text reviews the results of liver and kidney injuries from exposure to two or more chemicals, while other papers focus on lung and heart toxicity. For example, direct mechanism of cardio toxicity includes toxicity due to an increase in plasma concentrations of the compound, or as in latent cardiac toxicity that is a product of another action on another system of organs. Professors in pharmacology, practitioners of general medicine, specialists or researchers dealing with microchemistry, toxicology or drug therapy will find this reference valuable.
Download or read book Multiple Chemical Interactions written by Edward J. Calabrese and published by CRC Press. This book was released on 1990-12-19 with total page 842 pages. Available in PDF, EPUB and Kindle. Book excerpt: This classic work on a vitally important and new topic contains over 1200 pages of complete information on chemical interactions as it pertains to environmental and medical concerns. It illustrates principles of interactions so you will have the conceptual basis for predicting responses to complex environmental mixtures-apply it to specific situations-theoretical and practical. To date, environmental standards regulate the effects of a single pollutant. Multiple Chemical Interactions is exhaustive coverage of how the multitude of chemicals in our world interact with human health. This book gives us critically new and complete data on an emerging field that will be of interest to all environmental scientists, environmental and public health professionals, toxicologists, industrial hygienists, regulators and libraries.
Download or read book Toxicant Receptor Interactions written by Michael Denison and published by CRC Press. This book was released on 1998-08-10 with total page 260 pages. Available in PDF, EPUB and Kindle. Book excerpt: Many of the toxic effects elicited by xenobiotics can be explained at the molecular level by their interaction with receptors or by disruption or interference with receptor-mediated signal transduction pathways. This volume describes molecular approaches and reviews of current research. It provides reviews of numerous research areas which are direc
Download or read book Toxicological Evaluation of Chemical Interactions written by and published by . This book was released on 1994 with total page 704 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Download or read book Principles and Practice of Mixtures Toxicology written by Moiz Mumtaz and published by John Wiley & Sons. This book was released on 2011-05-23 with total page 625 pages. Available in PDF, EPUB and Kindle. Book excerpt: This first comprehensive treatment of the subject for more than a decade includes the latest research on nanoparticle toxicology. The practical handbook addresses all areas where toxic mixtures are encountered, from environmental via occupational to medical settings, giving special consideration to air and water, and to the specific requirements for study design in mixture toxicology. While no extensive prior knowledge or toxicological experience is required, the practice-oriented case studies and examples in the second part make this the ideal companion for the professional toxicologist in industry or healthcare institutions with little time for academic study.
Download or read book Alcohol Interactions with Drugs and Chemicals written by Edward J. Calabrese and published by CRC Press. This book was released on 2017-07-28 with total page 171 pages. Available in PDF, EPUB and Kindle. Book excerpt: Alcohol Interactions with Drugs and Chemicals is a concise volume that identifies, documents, and assesses the capacity of alcohol to alter the toxicity of chemical pollutants and drugs in animal models and humans. The book systematically assesses interactions according to general chemical classes of inorganic and organic agents. It also presents an integrative discussion of the significance of these findings to public health. Alcohol Interactions with Drugs and Chemicals will be a valuable reference tool for environmental scientists, toxicologists, epidemiologists, and alcohol researchers studying the interactions of alcohol with drugs and chemical pollutants.
Download or read book Mixture Toxicity written by Cornelis A. M. van Gestel and published by CRC Press. This book was released on 2016-04-19 with total page 312 pages. Available in PDF, EPUB and Kindle. Book excerpt: In the last decade and a half, great progress has been made in the development of concepts and models for mixture toxicity, both in human and environmental toxicology. However, due to their different protection goals, developments have often progressed in parallel but with little integration. Arguably the first book to clearly link ecotoxicology an
Download or read book Toxicological Profile for Lead written by and published by . This book was released on 2007 with total page 584 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Download or read book Clinical Toxicology written by Frank A. Barile and published by CRC Press. This book was released on 2010-02-15 with total page 484 pages. Available in PDF, EPUB and Kindle. Book excerpt: Examining the complex interactions associated with clinical toxicological events and chemical exposure of drug administration, this updated and revised Second Edition functions as a stand-alone text or reference of clinical toxicology for professionals, students of toxicology and pharmacy, as well as forensic toxicologists, occupational healthcare
Download or read book Metal Ions in Toxicology Effects Interactions Interdependencies written by Astrid Sigel and published by Walter de Gruyter GmbH & Co KG. This book was released on 2015-07-24 with total page 456 pages. Available in PDF, EPUB and Kindle. Book excerpt: Volume 8, solely devoted to the toxicology of metals and metalloids as well as their compounds, focuses on human health. Not surprisingly, all related research areas are rapidly developing due to the role of metals and metalloids in the environment, for the work place, for food and water supply, etc. Written by 40 internationally recognized experts, the 14 stimulating chapters provide an authoritative and timely resource for scientists working in the wide range from analytical, physical, inorganic, and environmental biochemistry all the way through to toxicology, physiology, and medicine. Volume 8 highlights, supported by nearly 1900 references, in a comprehensive and timely manner the principles of risk assessment regarding the effects of metals on human health. It examines how metal ions and their compounds affect the pulmonary, cardiovascular, gastrointestinal (including liver), hematological, immune, and neurological systems, the kidney, skin and eyes, as well as human reproduction and development. MILS-8 terminates with the role of metal ions as endocrine disrupters, in genotoxicity, and cancer risk.
Download or read book Handbook of Drug Interactions written by Ashraf Mozayani and published by Springer Science & Business Media. This book was released on 2003-10-15 with total page 662 pages. Available in PDF, EPUB and Kindle. Book excerpt: A concise compilation of the known interactions of the most commonly prescribed drugs, as well as their interaction with nonprescription compounds. The agents covered include CNS drugs, cardiovascular drugs, antibiotics, and NSAIDs. For each class of drugs the authors review the pharmacology, pharmacodynamics, pharmacokinetics, chemistry, metabolism, epidemiological occurrences, adverse reactions, and significant interactions. Environmental and social pharmacological issues are also addressed in chapters on food and alcohol drug interactions, nicotine and tobacco, and anabolic doping agents. Comprehensive and easy-to-use, Handbook of Drug Interactions: A Clinical and Forensic Guide provides physicians with all the information needed to avoid prescribing drugs with undesirable interactions, and toxicologists with all the data necessary to interpret possible interactions between drugs found simultaneously in patient samples.
Download or read book Barile s Clinical Toxicology written by Frank A. Barile and published by CRC Press. This book was released on 2019-04-24 with total page 530 pages. Available in PDF, EPUB and Kindle. Book excerpt: As with the two previous editions, Barile’s Clinical Toxicology: Principles and Mechanisms, Third edition, examines the complex interactions associated with clinical toxicological events as a result of therapeutic drug administration or chemical exposure. With special emphasis placed on signs and symptoms of diseases and pathology caused by toxins and clinical drugs, the new edition, examines the complex interactions associated with clinical toxicological events as a result of therapeutic drug administration or chemical exposure. The new edition presents the latest, up-to-date protocols for managing various toxic ingestions, and the antidotes and treatments associated with their pathology. In addition, the effect of toxins on a limited number of body systems and drug-induced adverse drug reactions are also covered. KEY FEATURES • Discusses source of the drug or chemical, pharmacological and toxicological mechanisms of action, detection, identification, and treatment • Examines the complex interactions associated with clinical toxicological events • Emphasizes the signs and symptoms of diseases and pathology caused by toxins and clinical drugs • Covers effect of toxins on body systems and drug-induced adverse reactions • Offers a unique perspective for toxicology, pharmacology, pharmacy and health professions students The target audience for this book is undergraduate and graduate toxicology students, clinical pharmacy (Pharm.D.) students, emergency medical personnel, regulatory agencies, and other related health science professionals. It satisfies an essential need for a concise yet detailed authoritative, fundamental text addressing the current principles of clinical toxicology.
Download or read book Drug Interactions in Infectious Diseases written by Stephen C. Piscitelli and published by Springer Science & Business Media. This book was released on 2007-10-28 with total page 534 pages. Available in PDF, EPUB and Kindle. Book excerpt: Over the past 25 years, the world’s population has witnessed an explosion in kno- edge about infectious diseases. The global population is coming to the realization that diseases long recognized to cause substantial suffering, such as malaria, tuberculosis, schistosomiasis, and hepatitis, can be diagnosed and treated, and that transmission can be prevented using tools that are available, and which may be becoming increasingly affordable. The global population is recognizing that few infections are local: the travel of humans, other animals, insects, and food transport pathogens around the world, often with astonishing rapidity. New pathogens are appearing, either newly recognized or newly developing, such as severe acute respiratory syndrome (SARS), avian inf- enza, metapneumovirus, or hepatitis C, which are causing human morbidity and m- tality. Finally, there is growing fear that dangerous pathogens may be intentionally introduced into human populations by deranged individuals or terrorist organizations. The potential to use drugs or biologic agents to treat and prevent infectious diseases has increased dramatically over the past quarter century as we have learned more about the biology of many of these agents, and as we have developed techniques to discover new agents by high throughput screening programs and by sophisticated drug design and synthesis.
Download or read book Comprehensive Toxicology written by and published by Elsevier. This book was released on 2017-12-01 with total page 8639 pages. Available in PDF, EPUB and Kindle. Book excerpt: Comprehensive Toxicology, Third Edition, Fifteen Volume Set discusses chemical effects on biological systems, with a focus on understanding the mechanisms by which chemicals induce adverse health effects. Organized by organ system, this comprehensive reference work addresses the toxicological effects of chemicals on the immune system, the hematopoietic system, cardiovascular system, respiratory system, hepatic toxicology, renal toxicology, gastrointestinal toxicology, reproductive and endocrine toxicology, neuro and behavioral toxicology, developmental toxicology and carcinogenesis, also including critical sections that cover the general principles of toxicology, cellular and molecular toxicology, biotransformation and toxicology testing and evaluation. Each section is examined in state-of-the-art chapters written by domain experts, providing key information to support the investigations of researchers across the medical, veterinary, food, environment and chemical research industries, and national and international regulatory agencies. Thoroughly revised and expanded to 15 volumes that include the latest advances in research, and uniquely organized by organ system for ease of reference and diagnosis, this new edition is an essential reference for researchers of toxicology. Organized to cover both the fundamental principles of toxicology and unique aspects of major organ systems Thoroughly revised to include the latest advances in the toxicological effects of chemicals on the immune system Features additional coverage throughout and a new volume on toxicology of the hematopoietic system Presents in-depth, comprehensive coverage from an international author base of domain experts
Download or read book Drug Drug Interactions Scientific and Regulatory Perspectives written by and published by Academic Press. This book was released on 1997-11-06 with total page 324 pages. Available in PDF, EPUB and Kindle. Book excerpt: Drug Drug Interactions is a comprehensive review of the scientific and regulatory perspectives of drug drug interactions from the point-of-view of academia, industry, and government regulatory agencies. This book is intended for professionals in the pharmaceutical industry, health care, and governmental regulatory agencies. Topics of interest include the mechanistic understanding of drug drug interactions, the prediction of drug drug interaction potential of new drugs, and the avoidance of clinically significant drug drug interaction in patients. Provides useful references on the science of drug-drug interactions Describes in a basic and comprehensive manner drug-drug interactions from the mechanistic viewpoint Contains original data from academic and industrial laboratories Presents an overview of regulatory agency positions
Download or read book Principles of Toxicological Interactions Associated with Multiple Chemical Exposures written by and published by National Academies. This book was released on 1980 with total page 218 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Download or read book Encyclopedia of Drug Metabolism and Interactions written by Alexander Lyubimov and published by Anchor Books. This book was released on 2012-01-01 with total page 698 pages. Available in PDF, EPUB and Kindle. Book excerpt: This multi-volume, state-of-the-art encyclopedia discusses all preclinical, clinical, toxicological, regulatory and marketing perspectives of drug metabolism and interactions. Methods and detailed protocols describing how to perform studies of metabolism and drug interactions are presented in one of the volumes. All aspects of drug metabolism and interactions in silico, in laboratory animals and in humans, are backed with a range of examples. This reference is essential for researchers interested in all aspects of drug development, and chemists, pharmacologists, pharmaceutical specialists, toxicologists, molecular toxicologists, and clinicians including practitioners and physicians.
