Download or read book Toxicological Evaluation of Chemical Interactions written by and published by . This book was released on 1994 with total page 704 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Download or read book Toxicological Evaluation of Chemical Interactions written by and published by . This book was released on 1994 with total page 176 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Download or read book Toxicological Evaluation of Chemical Interactions written by International Society for the Study of Xenobiotics and published by . This book was released on 1994 with total page pages. Available in PDF, EPUB and Kindle. Book excerpt:
Download or read book Toxicological Evaluation of Chemical Interactions written by and published by . This book was released on 1994 with total page 176 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Download or read book Toxicological Evaluation of Chemical Interactions Relevance of Social Environmental and Occupational Factors written by and published by . This book was released on 1992 with total page 141 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Download or read book Toxicological Evaluation of Chemical Interactions written by and published by . This book was released on 1994 with total page 0 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Download or read book Toxicological Evaluation of Chemical Interactions written by International Society for the Study of Xenobiotics and published by . This book was released on 1994 with total page 176 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Download or read book Toxicological Evaluation of Chemical Interactions written by International Society for the Study of Xenobiotics and published by . This book was released on 1992 with total page 141 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Download or read book Computational Toxicology written by John C. Lipscomb and published by Elsevier Inc. Chapters. This book was released on 2013-06-04 with total page 34 pages. Available in PDF, EPUB and Kindle. Book excerpt: Humans are exposed to chemicals through voluntary and involuntary actions; to natural and synthetic chemicals all day, every day. Single chemical risk assessments are complex in and of themselves, and the assessment of chemical mixtures exponentially increases the complexity for toxicologists, regulators, and the public. Chemicals produce effects in biological systems which may or may not be related to their toxicity; some effects may be adaptive or may not be a direct part of their mode or mechanism of toxic action. These terms are commonly used and may be distinguished based on the level of detail implied. Mode of action usually describes the effect of a toxicant at the cellular or organ level, while mechanism of action implies an understanding of the interaction of the toxicant at the molecular level. Chemicals can have the same mode of action, but act via different mechanisms. Components in a chemical mixture are characterized by mode and/or mechanism for the purpose of grouping, described later.
Download or read book Toxic Interactions written by Robin S. Goldstein and published by Elsevier. This book was released on 2013-10-22 with total page 503 pages. Available in PDF, EPUB and Kindle. Book excerpt: Toxic Interactions is a collection of papers that discusses the basic principles behind the mechanism of toxicological interactions. This book deals with interacting chemicals and their effects on certain exposed organs or molecules. Concerning discussion of the principles, contributed papers explain the role of xenobiotic biotransformation processes in inactivating reactive intermediates of toxicants. Other authors discuss the effects of endogenous molecules and the consequences of chemically induced depletion of protective agents, as well as the pharmacokinetic principles that affect chemical interactions. Several authors also review experiments on the types of chemicals that produce or increase the degree of toxicity. The text reviews the results of liver and kidney injuries from exposure to two or more chemicals, while other papers focus on lung and heart toxicity. For example, direct mechanism of cardio toxicity includes toxicity due to an increase in plasma concentrations of the compound, or as in latent cardiac toxicity that is a product of another action on another system of organs. Professors in pharmacology, practitioners of general medicine, specialists or researchers dealing with microchemistry, toxicology or drug therapy will find this reference valuable.
Download or read book Toxicological Risk Assessment of Chemicals written by Elsa Nielsen and published by CRC Press. This book was released on 2008-02-21 with total page 450 pages. Available in PDF, EPUB and Kindle. Book excerpt: Unlike many existing books on toxicology that cover either toxicity of a particular substance or toxicity of chemicals on particular organ systems, Toxicological Risk Assessment of Chemicals: A Practical Guide lays out the principle activities of conducting a toxicological risk assessment, including international approaches and methods for the risk
Download or read book Multiple Chemical Interactions written by Edward J. Calabrese and published by CRC Press. This book was released on 1990-12-19 with total page 842 pages. Available in PDF, EPUB and Kindle. Book excerpt: This classic work on a vitally important and new topic contains over 1200 pages of complete information on chemical interactions as it pertains to environmental and medical concerns. It illustrates principles of interactions so you will have the conceptual basis for predicting responses to complex environmental mixtures-apply it to specific situations-theoretical and practical. To date, environmental standards regulate the effects of a single pollutant. Multiple Chemical Interactions is exhaustive coverage of how the multitude of chemicals in our world interact with human health. This book gives us critically new and complete data on an emerging field that will be of interest to all environmental scientists, environmental and public health professionals, toxicologists, industrial hygienists, regulators and libraries.
Download or read book Science and Judgment in Risk Assessment written by National Research Council and published by National Academies Press. This book was released on 1994-01-01 with total page 668 pages. Available in PDF, EPUB and Kindle. Book excerpt: The public depends on competent risk assessment from the federal government and the scientific community to grapple with the threat of pollution. When risk reports turn out to be overblownâ€"or when risks are overlookedâ€"public skepticism abounds. This comprehensive and readable book explores how the U.S. Environmental Protection Agency (EPA) can improve its risk assessment practices, with a focus on implementation of the 1990 Clean Air Act Amendments. With a wealth of detailed information, pertinent examples, and revealing analysis, the volume explores the "default option" and other basic concepts. It offers two views of EPA operations: The first examines how EPA currently assesses exposure to hazardous air pollutants, evaluates the toxicity of a substance, and characterizes the risk to the public. The second, more holistic, view explores how EPA can improve in several critical areas of risk assessment by focusing on cross-cutting themes and incorporating more scientific judgment. This comprehensive volume will be important to the EPA and other agencies, risk managers, environmental advocates, scientists, faculty, students, and concerned individuals.
Download or read book Concepts in Toxicology written by John H. Duffus and published by Royal Society of Chemistry. This book was released on 2009 with total page 189 pages. Available in PDF, EPUB and Kindle. Book excerpt: This is a reference for those who need to understand the fundamental toxicological concepts that underlie both the scientific development of the subject and its practical applicaton in regulation and management of chemical safety.
Download or read book Toxicological Risk Assessment for Beginners written by José A. Torres and published by Springer. This book was released on 2015-03-27 with total page 266 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book serves as a comprehensive introductory guide to the practical aspects of risk assessment. Chapters include clearly defined objectives and summaries. The book includes: hazard identification, dose-response, exposure assessment, risk characterization, chemical mixtures, epidemiology, emerging issues and global perspectives with accessible language. The book concludes with a set of hypothetical case studies. Toxicological Risk Assessment for Beginners aims not to create an expert, but rather to provide readers with their first understanding of the risk assessment topic. This book was designed with the student in mind. We simplify a complex process for beginners and balance theory with practical aspects, but remain fluid enough to increase difficulty with case studies. By incorporating an action based, step by step approach to learning the risk assessment process, this book provides its readers with an elementary understanding of how the risk assessment process is initiated, developed and finished, making it a valuable guide for graduate students, post-doctoral fellows and early career scientists in industry.
Download or read book Mixture Toxicity written by Cornelis A. M. van Gestel and published by CRC Press. This book was released on 2016-04-19 with total page 312 pages. Available in PDF, EPUB and Kindle. Book excerpt: In the last decade and a half, great progress has been made in the development of concepts and models for mixture toxicity, both in human and environmental toxicology. However, due to their different protection goals, developments have often progressed in parallel but with little integration. Arguably the first book to clearly link ecotoxicology an
Download or read book Chemical Mixtures and Combined Chemical and Nonchemical Stressors written by Cynthia V. Rider and published by Springer. This book was released on 2018-02-16 with total page 554 pages. Available in PDF, EPUB and Kindle. Book excerpt: In this book, both basic and advanced concepts are discussed for considering mixtures from initial exposure characterization through evaluation of risk associated with combined exposures. This book will provide an introduction to key issues and multiple options for evaluating both the toxicity of mixtures as well as the risk associated with exposure to mixtures. Additionally, promising tools adapted from other disciplines will be discussed in the context of mixtures toxicology and risk assessment. Finally, the discussion will move beyond chemical mixtures to address incorporating non-chemical stressors into toxicity studies and cumulative risk assessments. Although exposure to multiple chemical and non-chemical stressors is the rule, not the exception, consideration of mixtures in toxicology and risk assessment continues to be a significant challenge. This book will be an essential resource for researchers and professionals in the fields of toxicology, epidemiology, exposure science, risk assessment, and statistics.
