Download or read book Analysis of Observational Health Care Data Using SAS written by Douglas E. Faries and published by SAS Press. This book was released on 2010 with total page 0 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book guides researchers in performing and presenting high-quality analyses of all kinds of non-randomized studies, including analyses of observational studies, claims database analyses, assessment of registry data, survey data, pharmaco-economic data, and many more applications. The text is sufficiently detailed to provide not only general guidance, but to help the researcher through all of the standard issues that arise in such analyses. Just enough theory is included to allow the reader to understand the pros and cons of alternative approaches and when to use each method. The numerous contributors to this book illustrate, via real-world numerical examples and SAS code, appropriate implementations of alternative methods. The end result is that researchers will learn how to present high-quality and transparent analyses that will lead to fair and objective decisions from observational data. This book is part of the SAS Press program.
Download or read book Explanation in Causal Inference written by Tyler J. VanderWeele and published by Oxford University Press, USA. This book was released on 2015 with total page 729 pages. Available in PDF, EPUB and Kindle. Book excerpt: A comprehensive examination of methods for mediation and interaction, VanderWeele's book is the first to approach this topic from the perspective of causal inference. Numerous software tools are provided, and the text is both accessible and easy to read, with examples drawn from diverse fields. The result is an essential reference for anyone conducting empirical research in the biomedical or social sciences.
Download or read book Experimental and Quasi experimental Designs for Generalized Causal Inference written by William R. Shadish and published by Cengage Learning. This book was released on 2002 with total page 664 pages. Available in PDF, EPUB and Kindle. Book excerpt: Sections include: experiments and generalised causal inference; statistical conclusion validity and internal validity; construct validity and external validity; quasi-experimental designs that either lack a control group or lack pretest observations on the outcome; quasi-experimental designs that use both control groups and pretests; quasi-experiments: interrupted time-series designs; regresssion discontinuity designs; randomised experiments: rationale, designs, and conditions conducive to doing them; practical problems 1: ethics, participation recruitment and random assignment; practical problems 2: treatment implementation and attrition; generalised causal inference: a grounded theory; generalised causal inference: methods for single studies; generalised causal inference: methods for multiple studies; a critical assessment of our assumptions.
Download or read book Handbook of Causal Analysis for Social Research written by Stephen L. Morgan and published by Springer Science & Business Media. This book was released on 2013-04-22 with total page 423 pages. Available in PDF, EPUB and Kindle. Book excerpt: What constitutes a causal explanation, and must an explanation be causal? What warrants a causal inference, as opposed to a descriptive regularity? What techniques are available to detect when causal effects are present, and when can these techniques be used to identify the relative importance of these effects? What complications do the interactions of individuals create for these techniques? When can mixed methods of analysis be used to deepen causal accounts? Must causal claims include generative mechanisms, and how effective are empirical methods designed to discover them? The Handbook of Causal Analysis for Social Research tackles these questions with nineteen chapters from leading scholars in sociology, statistics, public health, computer science, and human development.
Download or read book Regression Analysis for Categorical Moderators written by Herman Aguinis and published by Guilford Press. This book was released on 2004-01-01 with total page 230 pages. Available in PDF, EPUB and Kindle. Book excerpt: Does the stability of personality vary by gender or ethnicity? Does a particular therapy work better to treat clients with one type of personality disorder than those with another? Providing a solution to thorny problems such as these, Aguinis shows readers how to better assess whether the relationship between two variables is moderated by group membership through the use of a statistical technique, moderated multiple regression (MMR). Clearly written, the book requires only basic knowledge of inferential statistics. It helps students, researchers, and practitioners determine whether a particular intervention is likely to yield dissimilar outcomes for members of various groups. Associated computer programs and data sets are available at the author's website (http: //mypage.iu.edu/ haguinis/mmr).
Download or read book Digital Therapeutics written by Oleksandr Sverdlov and published by CRC Press. This book was released on 2022-12-06 with total page 462 pages. Available in PDF, EPUB and Kindle. Book excerpt: One of the hallmarks of the 21st century medicine is the emergence of digital therapeutics (DTx)—evidence-based, clinically validated digital technologies to prevent, diagnose, treat, and manage various diseases and medical conditions. DTx solutions have been gaining interest from patients, investors, healthcare providers, health authorities, and other stakeholders because of the potential of DTx to deliver equitable, massively scalable, personalized and transformative treatments for different unmet medical needs. Digital Therapeutics: Scientific, Statistical, Clinical, and Regulatory Aspects is an unparalleled summary of the current scientific, statistical, developmental, and regulatory aspects of DTx which is poised to become the fastest growing area of the biopharmaceutical and digital medicine product development. This edited volume intends to provide a systematic exposition to digital therapeutics through 19 peer-reviewed chapters written by subject matter experts in this emerging field. This edited volume is an invaluable resource for business leaders and researchers working in public health, healthcare, digital health, information technology, and biopharmaceutical industries. It will be also useful for regulatory scientists involved in the review of DTx products, and for faculty and students involved in an interdisciplinary research on digital health and digital medicine. Key Features: Provides the taxonomy of the concepts and a navigation tool for the field of DTx. Covers important strategic aspects of the DTx industry, thereby helping investors, developers, and regulators gain a better appreciation of the potential value of DTx. Expounds on many existing and emerging state-of-the art scientific and technological tools, as well as data privacy, ethical and regulatory considerations for DTx product development. Presents several case studies of successful development of some of the most remarkable DTx products. Provides some perspectives and forward-looking statements on the future of digital medicine.
Download or read book Introduction to Statistical Mediation Analysis written by David MacKinnon and published by Routledge. This book was released on 2012-10-02 with total page 479 pages. Available in PDF, EPUB and Kindle. Book excerpt: This volume introduces the statistical, methodological, and conceptual aspects of mediation analysis. Applications from health, social, and developmental psychology, sociology, communication, exercise science, and epidemiology are emphasized throughout. Single-mediator, multilevel, and longitudinal models are reviewed. The author's goal is to help the reader apply mediation analysis to their own data and understand its limitations. Each chapter features an overview, numerous worked examples, a summary, and exercises (with answers to the odd numbered questions). The accompanying CD contains outputs described in the book from SAS, SPSS, LISREL, EQS, MPLUS, and CALIS, and a program to simulate the model. The notation used is consistent with existing literature on mediation in psychology. The book opens with a review of the types of research questions the mediation model addresses. Part II describes the estimation of mediation effects including assumptions, statistical tests, and the construction of confidence limits. Advanced models including mediation in path analysis, longitudinal models, multilevel data, categorical variables, and mediation in the context of moderation are then described. The book closes with a discussion of the limits of mediation analysis, additional approaches to identifying mediating variables, and future directions. Introduction to Statistical Mediation Analysis is intended for researchers and advanced students in health, social, clinical, and developmental psychology as well as communication, public health, nursing, epidemiology, and sociology. Some exposure to a graduate level research methods or statistics course is assumed. The overview of mediation analysis and the guidelines for conducting a mediation analysis will be appreciated by all readers.
Download or read book Experiments in Public Management Research written by Oliver James and published by Cambridge University Press. This book was released on 2017-07-27 with total page 549 pages. Available in PDF, EPUB and Kindle. Book excerpt: An overview of experimental research and methods in public management, and their impact on theory, research practices and substantive knowledge.
Download or read book Measuring Racial Discrimination written by National Research Council and published by National Academies Press. This book was released on 2004-07-24 with total page 335 pages. Available in PDF, EPUB and Kindle. Book excerpt: Many racial and ethnic groups in the United States, including blacks, Hispanics, Asians, American Indians, and others, have historically faced severe discriminationâ€"pervasive and open denial of civil, social, political, educational, and economic opportunities. Today, large differences among racial and ethnic groups continue to exist in employment, income and wealth, housing, education, criminal justice, health, and other areas. While many factors may contribute to such differences, their size and extent suggest that various forms of discriminatory treatment persist in U.S. society and serve to undercut the achievement of equal opportunity. Measuring Racial Discrimination considers the definition of race and racial discrimination, reviews the existing techniques used to measure racial discrimination, and identifies new tools and areas for future research. The book conducts a thorough evaluation of current methodologies for a wide range of circumstances in which racial discrimination may occur, and makes recommendations on how to better assess the presence and effects of discrimination.
Download or read book Targeted Learning written by Mark J. van der Laan and published by Springer Science & Business Media. This book was released on 2011-06-17 with total page 628 pages. Available in PDF, EPUB and Kindle. Book excerpt: The statistics profession is at a unique point in history. The need for valid statistical tools is greater than ever; data sets are massive, often measuring hundreds of thousands of measurements for a single subject. The field is ready to move towards clear objective benchmarks under which tools can be evaluated. Targeted learning allows (1) the full generalization and utilization of cross-validation as an estimator selection tool so that the subjective choices made by humans are now made by the machine, and (2) targeting the fitting of the probability distribution of the data toward the target parameter representing the scientific question of interest. This book is aimed at both statisticians and applied researchers interested in causal inference and general effect estimation for observational and experimental data. Part I is an accessible introduction to super learning and the targeted maximum likelihood estimator, including related concepts necessary to understand and apply these methods. Parts II-IX handle complex data structures and topics applied researchers will immediately recognize from their own research, including time-to-event outcomes, direct and indirect effects, positivity violations, case-control studies, censored data, longitudinal data, and genomic studies.
Download or read book The Sage Handbook of Methods in Social Psychology written by Carol Sansone and published by SAGE. This book was released on 2004 with total page 562 pages. Available in PDF, EPUB and Kindle. Book excerpt: 'The Handbook of Methods in Social Psychology' gives researchers and students an overview of the rich history of methodological innovation in both basic and applied research within social psychology.
Download or read book Multiple Regression written by Leona S. Aiken and published by SAGE. This book was released on 1991 with total page 228 pages. Available in PDF, EPUB and Kindle. Book excerpt: This successful book, now available in paperback, provides academics and researchers with a clear set of prescriptions for estimating, testing and probing interactions in regression models. Including the latest research in the area, such as Fuller's work on the corrected/constrained estimator, the book is appropriate for anyone who uses multiple regression to estimate models, or for those enrolled in courses on multivariate statistics.
Download or read book Statistical Methods in Psychiatry and Related Fields written by Ralitza Gueorguieva and published by CRC Press. This book was released on 2017-11-20 with total page 355 pages. Available in PDF, EPUB and Kindle. Book excerpt: Data collected in psychiatry and related fields are complex because outcomes are rarely directly observed, there are multiple correlated repeated measures within individuals, there is natural heterogeneity in treatment responses and in other characteristics in the populations. Simple statistical methods do not work well with such data. More advanced statistical methods capture the data complexity better, but are difficult to apply appropriately and correctly by investigators who do not have advanced training in statistics. This book presents, at a non-technical level, several approaches for the analysis of correlated data: mixed models for continuous and categorical outcomes, nonparametric methods for repeated measures and growth mixture models for heterogeneous trajectories over time. Separate chapters are devoted to techniques for multiple comparison correction, analysis in the presence of missing data, adjustment for covariates, assessment of mediator and moderator effects, study design and sample size considerations. The focus is on the assumptions of each method, applicability and interpretation rather than on technical details. Features Provides an overview of intermediate to advanced statistical methods applied to psychiatry. Takes a non-technical approach with mathematical details kept to a minimum. Includes lots of detailed examples from published studies in psychiatry and related fields. Software programs, data sets and output are available on a supplementary website. The intended audience are applied researchers with minimal knowledge of statistics, although the book could also benefit collaborating statisticians. The book, together with the online materials, is a valuable resource aimed at promoting the use of appropriate statistical methods for the analysis of repeated measures data. Ralitza Gueorguieva is a Senior Research Scientist at the Department of Biostatistics, Yale School of Public Health. She has more than 20 years experience in statistical methodology development and collaborations with psychiatrists and other researchers, and is the author of over 130 peer-reviewed publications.
Download or read book The SAGE Encyclopedia of Research Design written by Bruce B. Frey and published by SAGE Publications. This book was released on 2022-01-27 with total page 3889 pages. Available in PDF, EPUB and Kindle. Book excerpt: The SAGE Encyclopedia of Research Design maps out how one makes decisions about research design, interprets data, and draws valid inferences, undertakes research projects in an ethical manner, and evaluates experimental design strategies and results. From A-to-Z, this four-volume work covers the spectrum of research design strategies and topics including, among other things: fundamental research design principles, ethics in the research process, quantitative versus qualitative and mixed-method designs, completely randomized designs, multiple comparison tests, diagnosing agreement between data and models, fundamental assumptions in analysis of variance, factorial treatment designs, complete and incomplete block designs, Latin square and related designs, hierarchical designs, response surface designs, split-plot designs, repeated measures designs, crossover designs, analysis of covariance, statistical software packages, and much more. Research design, with its statistical underpinnings, can be especially daunting for students and novice researchers. At its heart, research design might be described simply as a formalized approach toward problem solving, thinking, and acquiring knowledge, the success of which depends upon clearly defined objectives and appropriate choice of statistical design and analysis to meet those objectives. The SAGE Encyclopedia of Research Design will assist students and researchers with their work while providing vital information on research strategies.
Download or read book Theory Based Data Analysis for the Social Sciences written by Carol S. Aneshensel and published by SAGE. This book was released on 2013 with total page 473 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book presents the elaboration model for the multivariate analysis of observational quantitative data. This model entails the systematic introduction of "third variables" to the analysis of a focal relationship between one independent and one dependent variable to ascertain whether an inference of causality is justified. Two complementary strategies are used: an exclusionary strategy that rules out alternative explanations such as spuriousness and redundancy with competing theories, and an inclusive strategy that connects the focal relationship to a network of other relationships, including the hypothesized causal mechanisms linking the focal independent variable to the focal dependent variable. The primary emphasis is on the translation of theory into a logical analytic strategy and the interpretation of results. The elaboration model is applied with case studies drawn from newly published research that serve as prototypes for aligning theory and the data analytic plan used to test it; these studies are drawn from a wide range of substantive topics in the social sciences, such as emotion management in the workplace, subjective age identification during the transition to adulthood, and the relationship between religious and paranormal beliefs. The second application of the elaboration model is in the form of original data analysis presented in two Analysis Journals that are integrated throughout the text and implement the full elaboration model. Using real data, not contrived examples, the text provides a step-by-step guide through the process of integrating theory with data analysis in order to arrive at meaningful answers to research questions.
Download or read book Mobile Health written by James M. Rehg and published by Springer. This book was released on 2017-07-12 with total page 561 pages. Available in PDF, EPUB and Kindle. Book excerpt: This volume provides a comprehensive introduction to mHealth technology and is accessible to technology-oriented researchers and practitioners with backgrounds in computer science, engineering, statistics, and applied mathematics. The contributing authors include leading researchers and practitioners in the mHealth field. The book offers an in-depth exploration of the three key elements of mHealth technology: the development of on-body sensors that can identify key health-related behaviors (sensors to markers), the use of analytic methods to predict current and future states of health and disease (markers to predictors), and the development of mobile interventions which can improve health outcomes (predictors to interventions). Chapters are organized into sections, with the first section devoted to mHealth applications, followed by three sections devoted to the above three key technology areas. Each chapter can be read independently, but the organization of the entire book provides a logical flow from the design of on-body sensing technology, through the analysis of time-varying sensor data, to interactions with a user which create opportunities to improve health outcomes. This volume is a valuable resource to spur the development of this growing field, and ideally suited for use as a textbook in an mHealth course.
Download or read book Experimental and Quasi Experimental Designs for Research written by Donald T. Campbell and published by Ravenio Books. This book was released on 2015-09-03 with total page 172 pages. Available in PDF, EPUB and Kindle. Book excerpt: We shall examine the validity of 16 experimental designs against 12 common threats to valid inference. By experiment we refer to that portion of research in which variables are manipulated and their effects upon other variables observed. It is well to distinguish the particular role of this chapter. It is not a chapter on experimental design in the Fisher (1925, 1935) tradition, in which an experimenter having complete mastery can schedule treatments and measurements for optimal statistical efficiency, with complexity of design emerging only from that goal of efficiency. Insofar as the designs discussed in the present chapter become complex, it is because of the intransigency of the environment: because, that is, of the experimenter’s lack of complete control.
