Download or read book Global Climate Change Impacts in the United States written by U.S. Global Change Research Program and published by Cambridge University Press. This book was released on 2009-08-24 with total page 193 pages. Available in PDF, EPUB and Kindle. Book excerpt: Summarizes the science of climate change and impacts on the United States, for the public and policymakers.

Download or read book Arsenic Contamination in the World written by Susan Murcott and published by IWA Publishing. This book was released on 2012-09-30 with total page 341 pages. Available in PDF, EPUB and Kindle. Book excerpt: Arsenic Contamination in the World: an International Sourcebook provides a global compendium of cited arsenic occurrences in the world as they affect public health. This book details arsenic contamination by source, region and arsenic-affected country. Arsenic is identified in 105 countries and territories, representing a larger database than any previous published work. Sources of arsenic contamination are categorized as Anthropogenic, Geogenic, Volcanogenic, Coal, Mining and Petroleum-related. National, regional and international maps locate the affected areas and populations. A synthesis of critical country information includes an estimate of the exposed population of 226 million people worldwide. This reference work is an indispensable tool for medical doctors, public health workers, scientists, water experts, governments, industries, non-profit organizations and communities in identifying site-specific arsenic contamination. An extensive bibliography of peer-reviewed literature gives the reader important arsenic contamination locations as the first step towards remediation. This Sourcebook is updatable via an on-line annex which provides up-to-date information on new arsenic occurrences and developments. We invite readers to participate in updating this database at: http://www.iwawaterwiki.org/xwiki/bin/view/Articles/ExecutiveSummaryofArsenicContaminationintheWorld By synthesizing the known occurrences of arsenic world-wide, this reference book offers an essential tool for understanding and addressing the global arsenic geological-public health interface. Discounted ebook price available for customers from Developing Countries. Please contact [email protected] if you wish to purchase an ebook from a developing country @ £50.00 (PDF format). Author: Susan Murcott, Senior Lecturer, Civil and Environmental Engineering Department, Massachusetts Institute of Technology, USA Table of Contents: Executive Summary, African Region, Region of the Americas, Asia Region, European Region, Region of Australia and Oceania.

Download or read book Managing Disruptions in Business written by Rajagopal and published by Springer Nature. This book was released on 2022-01-11 with total page 437 pages. Available in PDF, EPUB and Kindle. Book excerpt: This volume discusses business disruptions as strategic to gain market competitiveness. It analyzes the convergence of innovation and technology, business practices, public policies, political ideologies, and consumer values to strengthen competitive business practices through disruptions. Bringing together contributions from global experts, the chapters add to knowledge on contemporary business models, business strategies, radical interventions in manufacturing, services, and marketing organizations. Disruptive innovations led by contemporary trends, tend to transform the market and consumers’ landscape. These trends include shifts from closed to open models of innovation, servitization, and moving from conventional manufacturing and marketing paradigms to industry 4.0 business philosophy. Focused on the triadic themes of disruption, innovation, and management in emerging markets, this book serves as a valuable compendium for research in entrepreneurship development, regional business and development, contemporary political ideologies, and changing social values.

Download or read book Planning For Drought written by Donald Wilhite and published by Westview Press. This book was released on 1987-10-19 with total page 620 pages. Available in PDF, EPUB and Kindle. Book excerpt:

Download or read book Texas Earthquakes written by Cliff Frohlich and published by University of Texas Press. This book was released on 2002 with total page 306 pages. Available in PDF, EPUB and Kindle. Book excerpt: When nature goes haywire in Texas, it isn't usually an earthshaking event. Though droughts, floods, tornadoes, and hail all keep Texans talking about the unpredictable weather, when it comes to earthquakes, most of us think we're on terra firma in this state. But we're wrong! Nearly every year, earthquakes large enough to be felt by the public occur somewhere in Texas. This entertaining, yet authoritative book covers "all you really need to know" about earthquakes in general and in Texas specifically. The authors explain how earthquakes are caused by natural forces or human activities, how they're measured, how they can be predicted, and how citizens and governments should prepare for them. They also thoroughly discuss earthquakes in Texas, looking at the occurrences and assessing the risks region by region and comparing the amount of seismic activity in Texas to other parts of the country and the world. The book concludes with a compendium of over one hundred recorded earthquakes in Texas from 1811 to 2000 that briefly describes the location, timing, and effects of each event.

Download or read book Introduction to Single Cell Omics written by Xinghua Pan and published by Frontiers Media SA. This book was released on 2019-09-19 with total page 129 pages. Available in PDF, EPUB and Kindle. Book excerpt: Single-cell omics is a progressing frontier that stems from the sequencing of the human genome and the development of omics technologies, particularly genomics, transcriptomics, epigenomics and proteomics, but the sensitivity is now improved to single-cell level. The new generation of methodologies, especially the next generation sequencing (NGS) technology, plays a leading role in genomics related fields; however, the conventional techniques of omics require number of cells to be large, usually on the order of millions of cells, which is hardly accessible in some cases. More importantly, harnessing the power of omics technologies and applying those at the single-cell level are crucial since every cell is specific and unique, and almost every cell population in every systems, derived in either vivo or in vitro, is heterogeneous. Deciphering the heterogeneity of the cell population hence becomes critical for recognizing the mechanism and significance of the system. However, without an extensive examination of individual cells, a massive analysis of cell population would only give an average output of the cells, but neglect the differences among cells. Single-cell omics seeks to study a number of individual cells in parallel for their different dimensions of molecular profile on genome-wide scale, providing unprecedented resolution for the interpretation of both the structure and function of an organ, tissue or other system, as well as the interaction (and communication) and dynamics of single cells or subpopulations of cells and their lineages. Importantly single-cell omics enables the identification of a minor subpopulation of cells that may play a critical role in biological process over a dominant subpolulation such as a cancer and a developing organ. It provides an ultra-sensitive tool for us to clarify specific molecular mechanisms and pathways and reveal the nature of cell heterogeneity. Besides, it also empowers the clinical investigation of patients when facing a very low quantity of cell available for analysis, such as noninvasive cancer screening with circulating tumor cells (CTC), noninvasive prenatal diagnostics (NIPD) and preimplantation genetic test (PGT) for in vitro fertilization. Single-cell omics greatly promotes the understanding of life at a more fundamental level, bring vast applications in medicine. Accordingly, single-cell omics is also called as single-cell analysis or single-cell biology. Within only a couple of years, single-cell omics, especially transcriptomic sequencing (scRNA-seq), whole genome and exome sequencing (scWGS, scWES), has become robust and broadly accessible. Besides the existing technologies, recently, multiplexing barcode design and combinatorial indexing technology, in combination with microfluidic platform exampled by Drop-seq, or even being independent of microfluidic platform but using a regular PCR-plate, enable us a greater capacity of single cell analysis, switching from one single cell to thousands of single cells in a single test. The unique molecular identifiers (UMIs) allow the amplification bias among the original molecules to be corrected faithfully, resulting in a reliable quantitative measurement of omics in single cells. Of late, a variety of single-cell epigenomics analyses are becoming sophisticated, particularly single cell chromatin accessibility (scATAC-seq) and CpG methylation profiling (scBS-seq, scRRBS-seq). High resolution single molecular Fluorescence in situ hybridization (smFISH) and its revolutionary versions (ex. seqFISH, MERFISH, and so on), in addition to the spatial transcriptome sequencing, make the native relationship of the individual cells of a tissue to be in 3D or 4D format visually and quantitatively clarified. On the other hand, CRISPR/cas9 editing-based In vivo lineage tracing methods enable dynamic profile of a whole developmental process to be accurately displayed. Multi-omics analysis facilitates the study of multi-dimensional regulation and relationship of different elements of the central dogma in a single cell, as well as permitting a clear dissection of the complicated omics heterogeneity of a system. Last but not the least, the technology, biological noise, sequence dropout, and batch effect bring a huge challenge to the bioinformatics of single cell omics. While significant progress in the data analysis has been made since then, revolutionary theory and algorithm logics for single cell omics are expected. Indeed, single-cell analysis exert considerable impacts on the fields of biological studies, particularly cancers, neuron and neural system, stem cells, embryo development and immune system; other than that, it also tremendously motivates pharmaceutic RD, clinical diagnosis and monitoring, as well as precision medicine. This book hereby summarizes the recent developments and general considerations of single-cell analysis, with a detailed presentation on selected technologies and applications. Starting with the experimental design on single-cell omics, the book then emphasizes the consideration on heterogeneity of cancer and other systems. It also gives an introduction of the basic methods and key facts for bioinformatics analysis. Secondary, this book provides a summary of two types of popular technologies, the fundamental tools on single-cell isolation, and the developments of single cell multi-omics, followed by descriptions of FISH technologies, though other popular technologies are not covered here due to the fact that they are intensively described here and there recently. Finally, the book illustrates an elastomer-based integrated fluidic circuit that allows a connection between single cell functional studies combining stimulation, response, imaging and measurement, and corresponding single cell sequencing. This is a model system for single cell functional genomics. In addition, it reports a pipeline for single-cell proteomics with an analysis of the early development of Xenopus embryo, a single-cell qRT-PCR application that defined the subpopulations related to cell cycling, and a new method for synergistic assembly of single cell genome with sequencing of amplification product by phi29 DNA polymerase. Due to the tremendous progresses of single-cell omics in recent years, the topics covered here are incomplete, but each individual topic is excellently addressed, significantly interesting and beneficial to scientists working in or affiliated with this field.

Download or read book Autonomous Technology written by Langdon Winner and published by MIT Press. This book was released on 1978-08-15 with total page 400 pages. Available in PDF, EPUB and Kindle. Book excerpt: The truth of the matter is that our deficiency does not lie in the want of well-verified "facts." What we lack is our bearings. The contemporary experience of things technological has repeatedly confounded our vision, our expectations, and our capacity to make intelligent judgments. Categories, arguments, conclusions, and choices that would have been entirely obvious in earlier times are obvious no longer. Patterns of perceptive thinking that were entirely reliable in the past now lead us systematically astray. Many of our standard conceptions of technology reveal a disorientation that borders on dissociation from reality. And as long as we lack the ability to make our situation intelligible, all of the "data" in the world will make no difference. From the Introduction

Download or read book Historical Dictionary of United States Intelligence written by Michael A. Turner and published by Rowman & Littlefield. This book was released on 2014-10-08 with total page 423 pages. Available in PDF, EPUB and Kindle. Book excerpt: While the United States has had some kind of intelligence capability throughout its history, its intelligence apparatus is young, dating only to the period immediately after World War II. Yet, in that short a time, it has undergone enormous changes—from the labor-intensive espionage and covert action establishment of the 1950s to a modern enterprise that relies heavily on electronic data, technology, satellites, airborne collection platforms, and unmanned aerial vehicles, to name a few. This second edition covers the history of United States intelligence, and includes several key features: Chronology Introductory essay Appendixes Bibliography Over 600 cross-referenced entries on key events, issues, people, operations, laws, regulations This book is an excellent access point for members of the intelligence community; students, scholars, and historians; legal experts; and general readers wanting to know more about the history of U.S. intelligence.

Download or read book Visions written by Michio Kaku and published by Oxford Paperbacks. This book was released on 1999-03-04 with total page 416 pages. Available in PDF, EPUB and Kindle. Book excerpt: This volume collects the research of today's scientists to explore the possibilities of the science of tomorrow. Among the issues covered are how decoding DNA will allow us to alter and reshape our genetic heritage, and how quantum physicists will harness the energy of the Universe.

Download or read book Cigarette Wars written by Cassandra Tate and published by Oxford University Press, USA. This book was released on 2000-06-15 with total page 224 pages. Available in PDF, EPUB and Kindle. Book excerpt: We live in an age when the cigarette industry is under almost constant attack. Few weeks pass without yet another report on the hazards of smoking, or news of another anti-cigarette lawsuit, or more restrictions on cigarette sales, advertising, or use. It's somewhat surprising, then, that very little attention has been given to the fact that America has traveled down this road before. Until now, that is. As Cassandra Tate reports in this fascinating work of historical scholarship, between 1890 and 1930, fifteen states enacted laws to ban the sale, manufacture, possession, and/or use of cigarettes--and no fewer than twenty-two other states considered such legislation. In presenting the history of America's first conflicts with Big Tobacco, Tate draws on a wide range of newspapers, magazines, trade publications, rare pamphlets, and many other manuscripts culled from archives across the country. Her thorough and meticulously researched volume is also attractively illustrated with numerous photographs, posters, and cartoons from this bygone era. Readers will find in Cigarette Wars an engagingly written and well-told tale of the first anti-cigarette movement, dating from the Victorian Age to the Great Depression, when cigarettes were both legally restricted and socially stigmatized in America. Progressive reformers and religious fundamentalists came together to curb smoking, but their efforts collapsed during World War I, when millions of soldiers took up the habit and cigarettes began to be associated with freedom, modernity, and sophistication. Importantly, Tate also illustrates how supporters of the early anti-cigarette movement articulated virtually every issue that is still being debated about smoking today; theirs was not a failure of determination, she argues in these pages, but of timing. A compelling narrative about several clashing American traditions--old vs. young, rural vs. urban, and the late nineteenth vs. early twentieth centuries--this work will appeal to all who are interested in America's love-hate relationship with what Henry Ford once called "the little white slaver."

Download or read book Rise of the Robots written by Martin Ford and published by Basic Books. This book was released on 2015-05-05 with total page 353 pages. Available in PDF, EPUB and Kindle. Book excerpt: The New York Times-bestselling guide to how automation is changing the economy, undermining work, and reshaping our lives Winner of Best Business Book of the Year awards from the Financial Times and from Forbes "Lucid, comprehensive, and unafraid . . . ;an indispensable contribution to a long-running argument." -- Los Angeles Times What are the jobs of the future? How many will there be? And who will have them? As technology continues to accelerate and machines begin taking care of themselves, fewer people will be necessary. Artificial intelligence is already well on its way to making "good jobs" obsolete: many paralegals, journalists, office workers, and even computer programmers are poised to be replaced by robots and smart software. As progress continues, blue and white collar jobs alike will evaporate, squeezing working -- and middle-class families ever further. At the same time, households are under assault from exploding costs, especially from the two major industries-education and health care-that, so far, have not been transformed by information technology. The result could well be massive unemployment and inequality as well as the implosion of the consumer economy itself. The past solutions to technological disruption, especially more training and education, aren't going to work. We must decide, now, whether the future will see broad-based prosperity or catastrophic levels of inequality and economic insecurity. Rise of the Robots is essential reading to understand what accelerating technology means for our economic prospects-not to mention those of our children-as well as for society as a whole.

Download or read book Drug Discovery written by Robert A. Maxwell and published by Springer Science & Business Media. This book was released on 2012-12-06 with total page 443 pages. Available in PDF, EPUB and Kindle. Book excerpt: This treatise had its origins in the authors' strong opinion that the discovery of new drugs, especially of innovative therapeutic agents, really does not happen as a spontaneous sequel to investiga tive research, no matter how penetrating such research may be. Rather, it seemed to us that the discovery of innovative therapeutic agents was a very active process, existing in and of itself, and demanding full attention-it was not simply a passive, dependent by-process of investigative research. And yet, many researchers some close confreres of the authors, others more distant-believed otherwise. We felt that their view reflected unrealistic thinking and that reality probably lay closer to what Beyer" maintained: We are taught to believe that if we can understand a disease it should be easy enough to figure out, say, the molecular configuration of a definitive receptor mechanism somewhere along the line and to design a specific drug . . . . And so we start out to understand the disease but never get around to doing much about therapy. The authors very soon realized that there was essentially no quantitive information available on just where and how innovative therapeutic agents were discovered. There were only anecdotal accounts, and these were able to be selected and presented in ways that could be used to defend any point of view.

Download or read book Nonlinear and Stochastic Climate Dynamics written by Christian L. E. Franzke and published by Cambridge University Press. This book was released on 2017-01-19 with total page 612 pages. Available in PDF, EPUB and Kindle. Book excerpt: It is now widely recognized that the climate system is governed by nonlinear, multi-scale processes, whereby memory effects and stochastic forcing by fast processes, such as weather and convective systems, can induce regime behavior. Motivated by present difficulties in understanding the climate system and to aid the improvement of numerical weather and climate models, this book gathers contributions from mathematics, physics and climate science to highlight the latest developments and current research questions in nonlinear and stochastic climate dynamics. Leading researchers discuss some of the most challenging and exciting areas of research in the mathematical geosciences, such as the theory of tipping points and of extreme events including spatial extremes, climate networks, data assimilation and dynamical systems. This book provides graduate students and researchers with a broad overview of the physical climate system and introduces powerful data analysis and modeling methods for climate scientists and applied mathematicians.

Download or read book Low Temperature Thermochronology written by Peter W. Reiners and published by Walter de Gruyter GmbH & Co KG. This book was released on 2018-12-17 with total page 644 pages. Available in PDF, EPUB and Kindle. Book excerpt: Volume 58 of Reviews in Mineralogy and Geochemistry presents 22 chapters covering many of the important modern aspects of thermochronology. The coverage of the chapters ranges widely, including historical perspective, analytical techniques, kinetics and calibrations, modeling approaches, and interpretational methods. In general, the chapters focus on intermediate- to low-temperature thermochronometry, though some chapters cover higher temperature methods such as monazite U/Pb closure profiles, and the same theory and approaches used in low-temperature thermochronometry are generally applicable to higher temperature systems. The widely used low- to medium-temperature thermochronometric systems are reviewed in detail in these chapters, but while there are numerous chapters reviewing various aspects of the apatite (U-Th)/He system, there is no chapter singularly devoted to it, partly because of several previous reviews recently published on this topic.

Download or read book The Lucifer Principle written by Howard Bloom and published by Open Road + Grove/Atlantic. This book was released on 2013-11-01 with total page 457 pages. Available in PDF, EPUB and Kindle. Book excerpt: “A philosophical look at the history of our species which alternated between fascinating and frightening . . . like reading Dean Koontz or Stephen King.” —Rocky Mountain News The Lucifer Principle is a revolutionary work that explores the intricate relationships among genetics, human behavior, and culture to put forth the thesis that “evil” is a by-product of nature’s strategies for creation and that it is woven into our most basic biological fabric. In a sweeping narrative that moves lucidly among sophisticated scientific disciplines and covers the entire span of the earth’s—as well as mankind’s—history, Howard Bloom challenges some of our most popular scientific assumptions. Drawing on evidence from studies of the most primitive organisms to those on ants, apes, and humankind, the author makes a persuasive case that it is the group, or “superorganism,” rather than the lone individual that really matters in the evolutionary struggle. But biology is not destiny, and human culture is not always the buffer to our most primitive instincts we would like to think it is. In these complex threads of thought lies the Lucifer Principle, and only through understanding its mandates will we able to avoid the nuclear crusades that await us in the twenty-first century. “A revolutionary vision of the relationship between psychology and history, The Lucifer Principle will have a profound impact on our concepts of human nature. It is astonishing that a book of such importance could be such a pleasure to read.”—Elizabeth F. Loftus, author of Memory

Download or read book The Environmental Law of the Sea written by Douglas M. Johnston and published by . This book was released on 1981 with total page 440 pages. Available in PDF, EPUB and Kindle. Book excerpt:

Download or read book Reservoir Characterization written by Larry Lake and published by Elsevier. This book was released on 2012-12-02 with total page 680 pages. Available in PDF, EPUB and Kindle. Book excerpt: Reservoir Characterization is a collection of papers presented at the Reservoir Characterization Technical Conference, held at the Westin Hotel-Galleria in Dallas on April 29-May 1, 1985. Conference held April 29-May 1, 1985, at the Westin Hotel—Galleria in Dallas. The conference was sponsored by the National Institute for Petroleum and Energy Research, Bartlesville, Oklahoma. Reservoir characterization is a process for quantitatively assigning reservoir properties, recognizing geologic information and uncertainties in spatial variability. This book contains 19 chapters, and begins with the geological characterization of sandstone reservoir, followed by the geological prediction of shale distribution within the Prudhoe Bay field. The subsequent chapters are devoted to determination of reservoir properties, such as porosity, mineral occurrence, and permeability variation estimation. The discussion then shifts to the utility of a Bayesian-type formalism to delineate qualitative ""soft"" information and expert interpretation of reservoir description data. This topic is followed by papers concerning reservoir simulation, parameter assignment, and method of calculation of wetting phase relative permeability. This text also deals with the role of discontinuous vertical flow barriers in reservoir engineering. The last chapters focus on the effect of reservoir heterogeneity on oil reservoir. Petroleum engineers, scientists, and researchers will find this book of great value.