Download or read book Children and Drug Safety written by Cynthia A Connolly and published by Rutgers University Press. This book was released on 2018-05-11 with total page 328 pages. Available in PDF, EPUB and Kindle. Book excerpt: Winner of the 2018 Arthur J. Viseltear Award from the Medical Care Section of the American Public Health Association Children and Drug Safety traces the development, use, and marketing of drugs for children in the twentieth century, a history that sits at the interface of the state, business, health care providers, parents, and children. This book illuminates the historical dimension of a clinical and policy issue with great contemporary significance—many of the drugs administered to children today have never been tested for safety and efficacy in the pediatric population. Each chapter of Children and Drug Safety engages with major turning points in pediatric drug development; themes of children’s risk, rights, protection and the evolving context of childhood; child-rearing; and family life in ways freighted with nuances of race, class, and gender. Cynthia A. Connolly charts the numerous attempts by Congress, the Food and Drug Administration, the American Academy of Pediatrics, and leading pediatric pharmacologists, scientists, clinicians, and parents to address a situation that all found untenable. Open access edition funded by the National Endowment for the Humanities. The text of this book is licensed under a Creative Commons Attribution NonCommercial-NoDerivatives 4.0 International License: https://creativecommons.org/licenses/by-nc-nd/4.0/
Download or read book Aspirin written by Diarmuid Jeffreys and published by Chemical Heritage Foundation. This book was released on 2008-12 with total page 352 pages. Available in PDF, EPUB and Kindle. Book excerpt: A fast-paced, medical-historical mystery, filled with twists and turns.-Chicago Tribune
Download or read book The Renaissance of Aspirin written by Glenn Parris and published by Xlibris Corporation. This book was released on 2013-05-16 with total page 404 pages. Available in PDF, EPUB and Kindle. Book excerpt: This is the story of Anita Thomas and Jack Wheaton, two young doctors unwittingly in possession of a designer antibody for the treatment of fibromyalgia syndrome. The new drug is effective, but dangerously flawed. The problem is Anita Thomas has developed a cheap, safe alternative agent. Naturally, after expenditure of a fortune in development, the drug manufactures are not at all pleased with her. The pieces unfold, as we follow Anita and Jack from beautiful upscale midtown to the seedier downtown counterparts of Boston and Atlanta over shadowed by deadly stalkers and embellished by amorous often comically frustrating misadventures. The Renaissance of Aspirin is peppered with industrial espionage, suspense and passion as the chase is on for the first cure for fibromyalgia. Entangled with colorful comrades such as Dasher Clay; Stormi Seales and Khandi Barr in their camp, Anita and Jack barely keep ahead of the treacherous cabal of nemeses; Luciana Velasquez and Jason Brasil led by the Über-villain, Orson Quirk. Paced in the tradition of The Pelican Brief, Coma or a contemporary Maltese Falcon, The Renaissance of Aspirin is both plot and character driven with a ly credible McGuffin at its core. These complex characters are funny, mean, desperate, lonely and at the same time very humanly imperfect. Readers will find their prickly exploits thoroughly entertaining.
Download or read book Developing a Protocol for Observational Comparative Effectiveness Research A User s Guide written by Agency for Health Care Research and Quality (U.S.) and published by Government Printing Office. This book was released on 2013-02-21 with total page 236 pages. Available in PDF, EPUB and Kindle. Book excerpt: This User’s Guide is a resource for investigators and stakeholders who develop and review observational comparative effectiveness research protocols. It explains how to (1) identify key considerations and best practices for research design; (2) build a protocol based on these standards and best practices; and (3) judge the adequacy and completeness of a protocol. Eleven chapters cover all aspects of research design, including: developing study objectives, defining and refining study questions, addressing the heterogeneity of treatment effect, characterizing exposure, selecting a comparator, defining and measuring outcomes, and identifying optimal data sources. Checklists of guidance and key considerations for protocols are provided at the end of each chapter. The User’s Guide was created by researchers affiliated with AHRQ’s Effective Health Care Program, particularly those who participated in AHRQ’s DEcIDE (Developing Evidence to Inform Decisions About Effectiveness) program. Chapters were subject to multiple internal and external independent reviews. More more information, please consult the Agency website: www.effectivehealthcare.ahrq.gov)
Download or read book Board Stiff Three E Book written by Christopher Gallagher and published by Elsevier Health Sciences. This book was released on 2008-11-20 with total page 440 pages. Available in PDF, EPUB and Kindle. Book excerpt: Think the anesthesia oral boards are no laughing matter? Then you haven’t read Board Stiff Three. The new edition of this popular anesthesia review book is written in the same winning style that was the hallmark of Board Stiff Too. Dr. Gallagher’s signature humor and engaging writing style make this terrific prep book a fun read while still delivering all the most important things you need to know for the boards. In addition to a thorough content review, the new edition also features an extensive section with self-assessment questions. It also includes a bonus DVD with simulated board scenarios that will further help you prepare for the boards. Provides the ideal study guide for the anesthesia oral board exams. Incorporates a unique and humorous approach to make braving the oral exams as enjoyable as possible. Uses the same format as the real exams: clinical scenes are presented, followed by preoperative, intraoperative, and postoperative questions. Includes a bonus DVD with simulated board scenarios.
Download or read book Microscale Chemistry written by John Skinner and published by Royal Society of Chemistry. This book was released on 1997 with total page 216 pages. Available in PDF, EPUB and Kindle. Book excerpt: Developing microscale chemistry experiments, using small quantities of chemicals and simple equipment, has been a recent initiative in the UK. Microscale chemistry experiments have several advantages over conventional experiments: They use small quantities of chemicals and simple equipment which reduces costs; The disposal of chemicals is easier due to the small quantities; Safety hazards are often reduced and many experiments can be done quickly; Using plastic apparatus means glassware breakages are minimised; Practical work is possible outside a laboratory. Microscale Chemistry is a book of such experiments designed for use in schools and colleges, and the ideas behind the experiments in it come from many sources, including chemistry teachers from all around the world. Current trends indicate that with the likelihood of further environmental legislation, the need for microscale chemistry teaching techniques and experiments is likely to grow. This book should serve as a guide in this process.
Download or read book Drug Induced Headache written by Hans-Christoph Diener and published by Springer Science & Business Media. This book was released on 2012-12-06 with total page 174 pages. Available in PDF, EPUB and Kindle. Book excerpt: M. WILKINSON Patients with frequent or daily headaches pose a very difficult problem for the physician who has to treat them, particularly as many patients think that there should be a medicine or medicines which give them instant relief. In the search for the compound which would meet this very natural desire, many drugs have been manufactured and the temptation for the physician is either to increase the dose of a drug which seems to be, at any rate, partially effective, or to add one or more drugs to those which the patient is already taking. Although there have been some references to the dangers of overdosage of drugs for migraine in the past, it was not until relatively recently that it was recognized that drugs given for the relief of headache, if taken injudiciously, may themselves cause headache. The first drugs to be implicated in this way were ergotamine and phenazone. In the case of ergotamine tartrate, the dangers of ergotism were well known as this was a disorder which had been known and written about for many years. In the treatment of headache, fully blown ergotism is rare and in recent years has usually been due to self-medication in doses much greater than those prescribed although there are a few recorded cases where toxic amounts have been given.
Download or read book Anatomy Physiology with Brief Atlas of the Human Body and Quick Guide to the Language of Science and Medicine E Book written by Kevin T. Patton and published by Elsevier Health Sciences. This book was released on 2022-03-21 with total page 1309 pages. Available in PDF, EPUB and Kindle. Book excerpt: A&P may be complicated, but learning it doesn't have to be! Anatomy & Physiology, 11th Edition uses a clear, easy-to-read approach to tell the story of the human body’s structure and function. Color-coded illustrations, case studies, and Clear View of the Human Body transparencies help you see the "Big Picture" of A&P. To jump-start learning, each unit begins by reviewing what you have already learned and previewing what you are about to learn. Short chapters simplify concepts with bite-size chunks of information. Conversational, storytelling writing style breaks down information into brief chapters and chunks of information, making it easier to understand concepts. 1,400 full-color photographs and drawings bring difficult A&P concepts to life and illustrate the most current scientific knowledge. UNIQUE! Clear View of the Human Body transparencies allow you to peel back the layers of the body, with a 22-page, full-color insert showing the male and female human body along several planes. The Big Picture and Cycle of Life sections in each chapter help you comprehend the interrelation of body systems and how the structure and function of these change in relation to age and development. Interesting sidebars include boxed features such as Language of Science and Language of Medicine, Mechanisms of Disease, Health Matters, Diagnostic Study, FYI, Sport and Fitness, and Career Choices. Learning features include outlines, key terms, and study hints at the start of each chapter. Chapter summaries, review questions, and critical thinking questions help you consolidate learning after reading each chapter. Quick Check questions in each chapter reinforce learning by prompting you to review what you have just read. UNIQUE! Comprehensive glossary includes more terms than in similar textbooks, each with an easy pronunciation guide and simplified translation of word parts — essential features for learning to use scientific and medical terminology! NEW! Updated content reflects more accurately the diverse spectrum of humanity. NEW! Updated chapters include Homeostasis, Central Nervous System, Lymphatic System, Endocrine Regulation, Endocrine Glands, and Blood Vessels. NEW! Additional and updated Connect It! articles on the Evolve website, called out in the text, help to illustrate, clarify, and apply concepts. NEW! Seven guided 3-D learning modules are included for Anatomy & Physiology.
Download or read book The Lupus Book written by Daniel J. Wallace and published by Oxford University Press. This book was released on 2005-06 with total page 305 pages. Available in PDF, EPUB and Kindle. Book excerpt: One of the world's leading authorities on lupus, who has treated over 2,000 lupus patients, discusses the newest breakthroughs in drug treatments and alternative therapies, as well as updated information on the immune system--in user-friendly language that any patient can understand.
Download or read book Acetylsalicylic Acid written by Karsten Schrör and published by John Wiley & Sons. This book was released on 2016-09-26 with total page 474 pages. Available in PDF, EPUB and Kindle. Book excerpt: Written by a leading expert on Aspirin-related research, this is the most comprehensive treatise on the pharmacological effects and clinical applications of one of the most successful drugs ever. The text is written with a wide audience in mind, and to be readily understandable for clinicians, pharmacists, biomedical researchers and pharmacologists alike. This second, completely revised edition contains the latest results of clinical and pharmacological research on Acetylsalicylic acid, addressing the multiple pharmacological properties of this famous drug with a balanced view on their translation into clinical practice, including prevention from cardiovascular diseases and colorectal cancer.
Download or read book Draplin Design Co written by Aaron James Draplin and published by Abrams. This book was released on 2016-05-17 with total page 834 pages. Available in PDF, EPUB and Kindle. Book excerpt: A funny, colorful, fascinating tour through the work and life of one of today’s most influential graphic designers. Esquire. Ford Motors. Burton Snowboards. The Obama Administration. While all of these brands are vastly different, they share at least one thing in common: a teeny little bit of Aaron James Draplin. Draplin is one of the new school of influential graphic designers who combine the power of design, social media, entrepreneurship, and DIY aesthetic to create a successful business and way of life. Pretty Much Everything is a mid-career survey of work, case studies, inspiration, road stories, lists, maps, how-tos, and advice. It includes examples of his work—posters, record covers, logos—and presents the process behind his design with projects like Field Notes and the “Things We Love” State Posters. Draplin also offers valuable advice and hilarious commentary that illustrates how much more goes into design than just what appears on the page. With Draplin’s humor and pointed observations on the contemporary design scene, Pretty Much Everything is the complete package.
Download or read book Empire of Pain written by Patrick Radden Keefe and published by Anchor. This book was released on 2021-04-13 with total page 574 pages. Available in PDF, EPUB and Kindle. Book excerpt: NEW YORK TIMES BESTSELLER • A NEW YORK TIMES NOTABLE BOOK OF THE YEAR • A grand, devastating portrait of three generations of the Sackler family, famed for their philanthropy, whose fortune was built by Valium and whose reputation was destroyed by OxyContin. From the prize-winning and bestselling author of Say Nothing. "A real-life version of the HBO series Succession with a lethal sting in its tail…a masterful work of narrative reportage.” – Laura Miller, Slate The history of the Sackler dynasty is rife with drama—baroque personal lives; bitter disputes over estates; fistfights in boardrooms; glittering art collections; Machiavellian courtroom maneuvers; and the calculated use of money to burnish reputations and crush the less powerful. The Sackler name has adorned the walls of many storied institutions—Harvard, the Metropolitan Museum of Art, Oxford, the Louvre. They are one of the richest families in the world, but the source of the family fortune was vague—until it emerged that the Sacklers were responsible for making and marketing a blockbuster painkiller that was the catalyst for the opioid crisis. Empire of Pain is the saga of three generations of a single family and the mark they would leave on the world, a tale that moves from the bustling streets of early twentieth-century Brooklyn to the seaside palaces of Greenwich, Connecticut, and Cap d’Antibes to the corridors of power in Washington, D.C. It follows the family’s early success with Valium to the much more potent OxyContin, marketed with a ruthless technique of co-opting doctors, influencing the FDA, downplaying the drug’s addictiveness. Empire of Pain chronicles the multiple investigations of the Sacklers and their company, and the scorched-earth legal tactics that the family has used to evade accountability. A masterpiece of narrative reporting, Empire of Pain is a ferociously compelling portrait of America’s second Gilded Age, a study of impunity among the super-elite and a relentless investigation of the naked greed that built one of the world’s great fortunes.
Download or read book The Tangled Web They Weave written by Ivan L. Preston and published by Univ of Wisconsin Press. This book was released on 1994 with total page 244 pages. Available in PDF, EPUB and Kindle. Book excerpt: Ivan L. Preston, recognized as a preeminent scholar of the legal dimensions of American advertising, has written The Tangled Web They Weave for the ordinary consumer as well as for advertisers and trade regulators. His frank aim is to demonstrate how advertising can better serve its audience. Advertising, Preston points out, is full of falsity that is quite legal. Indeed, clever presentation of lies can make advertising entertaining to consumers, and Preston provides lively examples and anecdotes of such cases. The problem with falsity in advertising, he argues, is not so much with the bald lie as it is with deception. It is in this thicket of implied claims that he shows us the dangers and indicates the need for regulatory adjustment. Preston takes us down the slippery slope, from the high ground of honest product claims to the unscrupulous bottom-of-the-barrel claims that are wholly false. Along the way he documents the subtle misrepresentations, half and lesser truths, and exploitations of our gullibility that abound in contemporary advertising. The cases he describes are sometimes comic and sometimes shocking and infuriating. Preston's agenda is not merely to cry Foul! He sees advertising as performing not only a legitimate but an important public service. It is in all our interests, therefore, to perfect and not just pillory. As he concludes, "It is the time to see a way to serve society by creating a standard of personal and corporate credibility under which all advertisers, regulators, and consumers should want to live."
Download or read book Medical and Dental Expenses written by and published by . This book was released on 1997 with total page 20 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Download or read book The Mouse and the Motorcycle written by Beverly Cleary and published by Harper Collins. This book was released on 2009-10-06 with total page 208 pages. Available in PDF, EPUB and Kindle. Book excerpt: In this imaginative adventure from Newbery Medal–winning author Beverly Cleary, a young mouse named Ralph is thrown into a world of excitement when a boy and his shiny toy motorcycle check in to the Mountain View Inn. When the ever-curious Ralph spots Keith's red toy motorcycle, he vows to ride it. So when Keith leaves the bike unattended in his room one day, Ralph makes his move. But with all this freedom (and speed!) come a lot of obstacles. Whether dodging a rowdy terrier or keeping his nosy cousins away from his new wheels, Ralph has a lot going on! And with a pal like Keith always looking out for him, there's nothing this little mouse can't handle. This timeless classic now features a foreword written by New York Times bestselling author Kate DiCamillo, as well as an exclusive interview with Beverly Cleary herself. The Mouse and the Motorcycle is perfect for independent reading or for shared reading at home or in a classroom. This fun story is the first of a trilogy, along with Runaway Ralph and Ralph S. Mouse, all inspired by the author's hope to create appealing books for boys and girls—and by the sight of her son playing with toy cars.
Download or read book In Cold Blood written by Truman Capote and published by Modern Library. This book was released on 2013-02-19 with total page 417 pages. Available in PDF, EPUB and Kindle. Book excerpt: Selected by the Modern Library as one of the 100 best nonfiction books of all time From the Modern Library’s new set of beautifully repackaged hardcover classics by Truman Capote—also available are Breakfast at Tiffany’s and Other Voices, Other Rooms (in one volume), Portraits and Observations, and The Complete Stories Truman Capote’s masterpiece, In Cold Blood, created a sensation when it was first published, serially, in The New Yorker in 1965. The intensively researched, atmospheric narrative of the lives of the Clutter family of Holcomb, Kansas, and of the two men, Richard Eugene Hickock and Perry Edward Smith, who brutally killed them on the night of November 15, 1959, is the seminal work of the “new journalism.” Perry Smith is one of the great dark characters of American literature, full of contradictory emotions. “I thought he was a very nice gentleman,” he says of Herb Clutter. “Soft-spoken. I thought so right up to the moment I cut his throat.” Told in chapters that alternate between the Clutter household and the approach of Smith and Hickock in their black Chevrolet, then between the investigation of the case and the killers’ flight, Capote’s account is so detailed that the reader comes to feel almost like a participant in the events.
Download or read book Ending Medical Reversal written by Vinayak K. Prasad and published by JHU Press. This book was released on 2015-11 with total page 276 pages. Available in PDF, EPUB and Kindle. Book excerpt: Medications such as Vioxx and procedures such as vertebroplasty for back pain are among the medical "advances" that turned out to be dangerous or useless. What Dr. Vinayak K. Prasad and Dr. Adam S. Cifu call medical reversal happens when doctors start using a medication, procedure, or diagnostic tool without a robust evidence base—and then stop using it when it is found not to help, or even to harm, patients. In Ending Medical Reversal, Drs. Prasad and Cifu narrate fascinating stories from every corner of medicine to explore why medical reversals occur, how they are harmful, and what can be done to avoid them. They explore the difference between medical innovations that improve care and those that only appear to be promising. They also outline a comprehensive plan to reform medical education, research funding and protocols, and the process for approving new drugs that will ensure that more of what gets done in doctors' offices and hospitals is truly effective. "Every doctor should read this book."—JAMA Internal Medicine "[A]n excellent and realistic discussion of some of the horror stories that occur in medical practice . . . Highly recommended."—Choice "Ending Medical Reversal goes far in teaching medical students and practicing physicians alike how to learn on our own."—The Lancet "This has to be on the reading list for medical and nursing students."—Nursing Times "Ending Medical Reversal presents persuasive evidence that many current standard-of-care treatments are probably ineffective or harmful, thoroughly explains how such treatments came to be accepted, and proposes a number of ways to address the general problem (only some of which involve avaricious companies and mercenary physicians) and minimize its impact on a specific patient."—Journal of Clinical Research Best Practices "Dr. Prasad and Dr. Cifu offer a five-step plan, including pointers for determining if a given treatment is really able to do what you want it to do, and advice on finding a like-minded doctor who won't object to a certain amount of back-seat driving."—The New York Times "When I describe Ending Medical Reversal as revolutionary, I don't use the term lightly. Go out and read it—right now."—Common Sense Family Doctor "Should be considered for undergraduate reading lists. Keep a copy in the pharmacy or your briefcase as a great icebreaker or discussion point with other local healthcare professionals."—The Pharmaceutical Journal
