Download or read book Therapeutic Radionuclide Generators written by International Atomic Energy Agency and published by . This book was released on 2009 with total page 0 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Download or read book Therapeutic Radionuclide Generators written by International Atomic Energy Agency and published by . This book was released on 2009 with total page 0 pages. Available in PDF, EPUB and Kindle. Book excerpt: Radionuclide generators are a cost effective and efficient means to enhance the availability of short lived radioisotopes used in medicine and industry. This publication presents technologies for the development of 90Sr/90Y and 188W/188Re generator systems and provides details about the analytical methods that are used for evaluating the radionuclides to be used for basic research and radiopharmaceuticals preparation.
Download or read book Radionuclide Generators written by Furn F. Knapp and published by . This book was released on 1984 with total page 256 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Download or read book Therapeutic Radionuclide Generators written by IAEA. and published by . This book was released on 2009 with total page 248 pages. Available in PDF, EPUB and Kindle. Book excerpt: Radionuclide generators are a cost effective and efficient means to enhance the availability of short lived radioisotopes used in medicine and industry. This publication presents technologies for the development of 90Sr/90Y and 188W/188Re generator systems and provides details about the analytical methods that are used for evaluating the radionuclides to be used for basic research and radiopharmaceuticals preparation.
Download or read book Handbook of Nuclear Chemistry written by Attila Vértes and published by Springer Science & Business Media. This book was released on 2010-12-10 with total page 3693 pages. Available in PDF, EPUB and Kindle. Book excerpt: This revised and extended 6 volume handbook set is the most comprehensive and voluminous reference work of its kind in the field of nuclear chemistry. The Handbook set covers all of the chemical aspects of nuclear science starting from the physical basics and including such diverse areas as the chemistry of transactinides and exotic atoms as well as radioactive waste management and radiopharmaceutical chemistry relevant to nuclear medicine. The nuclear methods of the investigation of chemical structure also receive ample space and attention. The international team of authors consists of scores of world-renowned experts - nuclear chemists, radiopharmaceutical chemists and physicists - from Europe, USA, and Asia. The Handbook set is an invaluable reference for nuclear scientists, biologists, chemists, physicists, physicians practicing nuclear medicine, graduate students and teachers - virtually all who are involved in the chemical and radiopharmaceutical aspects of nuclear science. The Handbook set also provides further reading via the rich selection of references.
Download or read book Advancing Nuclear Medicine Through Innovation written by National Research Council and published by National Academies Press. This book was released on 2007-09-11 with total page 173 pages. Available in PDF, EPUB and Kindle. Book excerpt: Nearly 20 million nuclear medicine procedures are carried out each year in the United States alone to diagnose and treat cancers, cardiovascular disease, and certain neurological disorders. Many of the advancements in nuclear medicine have been the result of research investments made during the past 50 years where these procedures are now a routine part of clinical care. Although nuclear medicine plays an important role in biomedical research and disease management, its promise is only beginning to be realized. Advancing Nuclear Medicine Through Innovation highlights the exciting emerging opportunities in nuclear medicine, which include assessing the efficacy of new drugs in development, individualizing treatment to the patient, and understanding the biology of human diseases. Health care and pharmaceutical professionals will be most interested in this book's examination of the challenges the field faces and its recommendations for ways to reduce these impediments.
Download or read book Radiopharmaceuticals for Therapy written by F. F. (Russ) Knapp and published by Springer. This book was released on 2016-01-20 with total page 357 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book provides detailed information on therapeutic radiopharmaceuticals and discusses emerging technologies which have potential for broad clinical implementation. Recent advances in molecular biology, radiopharmaceutical chemistry and radioisotope production have stimulated a new era for the use of radiopharmaceuticals for targeted radionuclide therapy (TRT). Emerging clinical trials include use of peptides and monoclonal antibodies radiolabeled with therapeutic radionuclides for cancer therapy. In addition, small molecules are used for the treatment of chronic diseases such as metastatic bone pain palliation and radiation synovectomy of inflammatory joints. In the interventional arena, therapy of primary and metastatic liver cancer and arterial restenosis following angioplasty of both the coronary and peripheral arteries are being explored. Reactor and accelerator production of therapeutic radioisotopes is also integrated into these discussions. The development and use of radiopharmaceutical targeting characteristics required for treatment of specific disease processes and how these are implemented for radiopharmaceutical design strategies are also described. Radiopharmaceuticals for Therapy will benefit audiences in nuclear medicine and radionuclide therapy and will thus prove an invaluable source of up-to-date information for students, radiopharmaceutical scientists and professionals working in the radiopharmacy and nuclear medicine specialties.
Download or read book Molybdenum 99 for Medical Imaging written by National Academies of Sciences, Engineering, and Medicine and published by National Academies Press. This book was released on 2016-11-28 with total page 264 pages. Available in PDF, EPUB and Kindle. Book excerpt: The decay product of the medical isotope molybdenum-99 (Mo-99), technetium-99m (Tc-99m), and associated medical isotopes iodine-131 (I-131) and xenon-133 (Xe-133) are used worldwide for medical diagnostic imaging or therapy. The United States consumes about half of the world's supply of Mo-99, but there has been no domestic (i.e., U.S.-based) production of this isotope since the late 1980s. The United States imports Mo-99 for domestic use from Australia, Canada, Europe, and South Africa. Mo-99 and Tc-99m cannot be stockpiled for use because of their short half-lives. Consequently, they must be routinely produced and delivered to medical imaging centers. Almost all Mo-99 for medical use is produced by irradiating highly enriched uranium (HEU) targets in research reactors, several of which are over 50 years old and are approaching the end of their operating lives. Unanticipated and extended shutdowns of some of these old reactors have resulted in severe Mo-99 supply shortages in the United States and other countries. Some of these shortages have disrupted the delivery of medical care. Molybdenum-99 for Medical Imaging examines the production and utilization of Mo-99 and associated medical isotopes, and provides recommendations for medical use.
Download or read book New Radionuclide Generator Systems for Use in Nuclear Medicine written by and published by . This book was released on 1979 with total page pages. Available in PDF, EPUB and Kindle. Book excerpt: A current emphasis in nuclear medicine is to better match the physical lifetime of the radionuclides used in vivo for diagnosis and treatment to the biological lifetime of the diagnostic procedure or to minimize radiation dose to areas other than those to be treated. In many cases the biological lifetime is on the order of minutes. Since the direct production of radionuclides with half lives of minutes requires the user to be near a suitable reactor or accelerator, this study was undertaken to produce short-lived radionuclides indirectly. If a long-lived radionuclide decays into a short-lived radionuclide, quick separation of the daughter activity from the parent enables the user to have a short-lived daughter while freeing him from the constraint of proximity to a cyclotron. Systems where a short-lived daughter is separated from a long-lived parent are called radionuclide generators. Two generator systems were developed for use in nuclear medicine, one in diagnostic work and the other for therapeutic work. The yield and breakthrough characteristics were within the limits required to minimize unnecessary radiation exposure in patients. Two parent radionuclides were produced using /sup 4/He beams available from medium energy cyclotrons. The yield was high enough to produce generators that would be useful in clinical applications.
Download or read book The Development and Use of Radionuclide Generators in Nuclear Medicine Recent Advances and Future Perspectives written by and published by . This book was released on 1998 with total page 16 pages. Available in PDF, EPUB and Kindle. Book excerpt: Although the trend in radionuclide generator research has declined, radionuclide generator systems continue to play an important role in nuclear medicine. Technetium-99m obtained from the molybdenum-99/technetium-99m generator system is used in over 80% of all diagnostic clinical studies and there is increasing interest and use of therapeutic radioisotopes obtained from generator systems. This paper focuses on a discussion of the major current areas of radionuclide generator research, and the expected areas of future research and applications.
Download or read book Radiotracer Generators for Industrial Applications written by International Atomic Energy Agency and published by . This book was released on 2013 with total page 0 pages. Available in PDF, EPUB and Kindle. Book excerpt: Provides a unique source of information pertaining to the development of radiotracer generators and their use in troubleshooting and optimizing industrial processes. The publication describes the results of research undertaken on the characterization of 68Ge/68Ga, 137Cs/137mBa, 99Mo/99mTc and 113Sn/113mIn radiotracer generators.
Download or read book Medical Radionuclide Production written by Syed M. Qaim and published by de Gruyter. This book was released on 2019 with total page 0 pages. Available in PDF, EPUB and Kindle. Book excerpt: The work describes the production technology of standard medical radionuclides using reactors and cyclotrons for patient diagnosis and therapy. A special focus lies on the science and technology involved in the development of novel radionuclides for positron emission tomography (PET) and internal targeted radiotherapy. The availability of those radionuclides is opening up new potential in clinical research, especially in neurology, cardiology and oncology. The future perspectives of the developing technology are also discussed.
Download or read book Production of Long Lived Parent Radionuclides for Generators 68Ge 82Sr 90Sr and 188W written by International Atomic Energy Agency and published by United Nations Publications. This book was released on 2010 with total page 111 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book provides information on the production and processing of four important long lived parent radionuclides, 68Ge, 82Sr, 90Sr and 188W, used for the preparation of generators for nuclear medicine applications such as positron emission tomography and therapy. It includes descriptions of the production routes for and process chemistry of the selected parent radionuclides, including relevant separation approaches. Information on use of the generator system and on physical and chemical characteristics is also provided.
Download or read book Handbook of Radiopharmaceuticals written by Michael J. Welch and published by John Wiley & Sons. This book was released on 2003-01-17 with total page 872 pages. Available in PDF, EPUB and Kindle. Book excerpt: A comprehensive, authoritative and up-to-date reference for the newcomer to radiopharmaceuticals and those already in the field. Radiopharmaceuticals are used to detect and characterise disease processes, or normal biological function, in living cells, animals or humans. Used as tracer molecules, they map the distribution, uptake and metabolism of the molecule in clinical studies, basic research or applied research. The area of radiopharmaceuticals is expanding rapidly. The number of PET centers in the world is increasing at 20% per year, and many drug companies are utilising PET and other forms of radiopharmaceutical imaging to evaluate products. * Readers will find coverage on a number of important topics such as radionuclide production, PET and drug development, and regulations * Explains how to use radiopharmaceuticals for the diagnosis and therapy of cancer and other diseases * The editors and a majority of the contributors are from the United States
Download or read book Trends in Radiopharmaceuticals ISTR 2019 written by International Atomic Energy Agency and published by . This book was released on 2021-02-28 with total page 0 pages. Available in PDF, EPUB and Kindle. Book excerpt: The use of radiopharmaceuticals is an important tool not only for management of diseases and dysfunctions, but also for better understanding human diseases and developing effective treatment options, such as in the case of neurology. In this context, there is concern of continuous, impressive progress in nuclear medicine which is linked to the development of new radiopharmaceuticals and efficient production of relevant radioisotopes. These proceedings highlight the main findings and developments discussed during the International Symposium on Trends in Radiopharmaceuticals. They cover the key issues and advances in the field of radiopharmaceuticals from development, production, and use of diagnostic, therapeutic, and theranostic radioisotopes and radiopharmaceuticals, as well as regulatory and licensing issues related to their production. Additional topics addressed were education, certification and training methodologies. A supplementary file contains the detailed programme of the symposium and the abstracts of all oral and poster presentations.
Download or read book Fundamentals of Nuclear Pharmacy written by Gopal B. Saha and published by Springer. This book was released on 2017-11-11 with total page 430 pages. Available in PDF, EPUB and Kindle. Book excerpt: Currently an estimated 17 million nuclear medicine procedures are performed each year in the US and constantly evolving, as new radiopharmaceuticals and imaging techniques are introduced for better diagnosis and treatment of human diseases. In keeping up with new developments, the Seventh Edition of Fundamentals of Nuclear Pharmacy chronicles the advancements in radiopharmaceuticals and their use in clinical applications. It discusses basic concepts such as the atom, radioactive decay, instrumentation and production of radionuclides, and explores the design, labeling, characteristics and quality control of radiopharmaceuticals. Radiation regulations and diagnostic and therapeutic applications of radiopharmaceuticals are detailed. Thoroughly updated, the Seventh Edition includes new topics such as alternative productions of 99Mo; production of 64Cu, 86Y, 89Zr, 177Lu, 223Ra; synthesis and clinical uses of new radiopharmaceuticals such as DaTscan, Xofigo, Amyvid, Neuraceq, Vizamyl, Axumin and 68Ga-DOTATATE; dosimetry of new radiopharmaceuticals; theranostic agents and translational medicine. It features numerous examples, diagrams, and images to further clarify the information and offers end- of-chapter questions to help readers assess their comprehension of the material. Recognized as a classic text on nuclear chemistry and pharmacy and acclaimed for its concise and easy-to-understand presentation, Fundamentals of Nuclear Pharmacy is an authoritative resource for nuclear medicine physicians, residents, students, and technologists.
Download or read book Yttrium 90 and Rhenium 188 Radiopharmaceuticals for Radionuclide Therapy written by International Atomic Energy Agency and published by . This book was released on 2015-02-17 with total page 314 pages. Available in PDF, EPUB and Kindle. Book excerpt:
