Download or read book Theoretical and Experimental Insights into Immunology written by Alan S. Perelson and published by Springer Science & Business Media. This book was released on 2013-06-29 with total page 485 pages. Available in PDF, EPUB and Kindle. Book excerpt: Immunology is largely a science of observation and experimentation, and these approaches have lead to great increases in our knowledge of the genes, molecules and cells of the immune system. This book is an up-to-date discussion of the current state of modelling and theoretical work in immunology, of the impact of theory on experiment, and of future directions for theoretical research. Among the topics discussed are the function and evolution of the immune system, computer modelling of the humoral immune response and of idiotypic networks and idiotypic mimicry, T-cell memory, cryptic peptides, new views and models of AIDS and autoimmunity, and the shaping of the immune repertoire by early presented antigens and self immunoglobulin.
Download or read book MATHEMATICAL MODELS OF LIFE SUPPORT SYSTEMS Volume II written by Valeri I. Agoshko and published by EOLSS Publications. This book was released on 2009-10-10 with total page 504 pages. Available in PDF, EPUB and Kindle. Book excerpt: Mathematical Models of Life Support Systems is a component of Encyclopedia of Mathematical Sciences in which is part of the global Encyclopedia of Life Support Systems (EOLSS), an integrated compendium of twenty one Encyclopedias. The Theme is organized into several topics which represent the main scientific areas of the theme: The first topic, Introduction to Mathematical Modeling discusses the foundations of mathematical modeling and computational experiments, which are formed to support new methodologies of scientific research. The succeeding topics are Mathematical Models in - Water Sciences; Climate; Environmental Pollution and Degradation; Energy Sciences; Food and Agricultural Sciences; Population; Immunology; Medical Sciences; and Control of Catastrophic Processes. These two volumes are aimed at the following five major target audiences: University and College students Educators, Professional practitioners, Research personnel and Policy analysts, managers, and decision makers and NGOs.
Download or read book Environmental Radiation Effects on Mammals written by Olga A. Smirnova and published by Springer. This book was released on 2016-10-14 with total page 374 pages. Available in PDF, EPUB and Kindle. Book excerpt: Dr. Smirnova's updated text is devoted to the theoretical studies of radiation effects on mammals. It summarizes 35 years of results the author obtained from analyzing dose rate equivalents for the Galactic Cosmic Rays (GCR) and for Solar Particles Events (SPE). This edition also includes two new chapters on skin epidermal epithelium and risk assessment for myeloid leukemia, as well as extended revisions addressing the radiation effects on the blood-forming system. Mathematical models are used to explain the effects of both acute and chronic irradiation on the dynamics of vital body systems, like the hematopoietic system, the development of autoimmune diseases, and the mortality dynamics in homogeneous and nonhomogeneous mammalian populations. The proposed methodology of these studies, the models themselves, and the obtained results are of a great theoretical significance and can find wide practical use.
Download or read book Theoretical Immunology part I written by Alan Perelson and published by Westview Press. This book was released on 1988-01-21 with total page 438 pages. Available in PDF, EPUB and Kindle. Book excerpt: Assuming that the complex phenomena underlying the operation of the immune system may be better understood through the collaborative efforts of theorists and experimentalists viewing the same phenomen
Download or read book Mathematical Modelling of Immune Response in Infectious Diseases written by Guri I. Marchuk and published by Springer Science & Business Media. This book was released on 2013-04-17 with total page 356 pages. Available in PDF, EPUB and Kindle. Book excerpt: Beginning his work on the monograph to be published in English, this author tried to present more or less general notions of the possibilities of mathematics in the new and rapidly developing science of infectious immunology, describing the processes of an organism's defence against antigen invasions. The results presented in this monograph are based on the construc tion and application of closed models of immune response to infections which makes it possible to approach problems of optimizing the treat ment of chronic and hypertoxic forms of diseases. The author, being a mathematician, had creative long-Iasting con tacts with immunologists, geneticist, biologists, and clinicians. As far back as 1976 it resulted in the organization of a special seminar in the Computing Center of Siberian Branch of the USSR Academy of Sci ences on mathematical models in immunology. The seminar attracted the attention of a wide circle of leading specialists in various fields of science. All these made it possible to approach, from a more or less united stand point, the construction of models of immune response, the mathematical description of the models, and interpretation of results.
Download or read book National Library of Medicine Current Catalog written by National Library of Medicine (U.S.) and published by . This book was released on 1993 with total page 1328 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Download or read book Current Catalog written by National Library of Medicine (U.S.) and published by . This book was released on 1993 with total page 1628 pages. Available in PDF, EPUB and Kindle. Book excerpt: First multi-year cumulation covers six years: 1965-70.
Download or read book Thinking About Biology written by Wilfred Stein and published by CRC Press. This book was released on 2018-03-08 with total page 272 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book discusses the emergence of life, the development of the individual, and the study of the interaction between individuals and species. It gives the student of theoretical biology some idea of the flavor of current research in the field.
Download or read book Collective Consciousness and Its Discontents written by Rodrick Wallace and published by Springer Science & Business Media. This book was released on 2007-11-28 with total page 210 pages. Available in PDF, EPUB and Kindle. Book excerpt: An earlier book by Rodrick Wallace entitled Consciousness: A Mathematical Treatment of the Global Neuronal Workspace Model, introduced a formal information-theoretic approach to individual consciousness. This latest book takes a more formal 'groupoid' perspective to its predecessor and generalizes the results presented in that earlier book. It applies a multiple-workspace version of Dr. Wallace’s earlier consciousness model to large-scale institutional cognition.
Download or read book Artificial Immune Systems and Their Applications written by Dipankar Dasgupta and published by Springer Science & Business Media. This book was released on 2012-12-06 with total page 318 pages. Available in PDF, EPUB and Kindle. Book excerpt: This is a pioneering work on the emerging field of artificial immune systems-highly distributed systems based on the principles of the natural system. Like artificial neural networks, artificial immune systems can learn new information and recall previously learned information. This book provides an overview of artificial immune systems, explaining its applications in areas such as immunological memory, anomaly detection algorithms, and modeling the effects of prior infection on vaccine efficacy.
Download or read book Advances in Artificial Intelligence IBERAMIA 2002 written by Francisco J. Garijo and published by Springer. This book was released on 2003-06-30 with total page 974 pages. Available in PDF, EPUB and Kindle. Book excerpt: The 8th Ibero-American Conference on Artificial Intelligence, IBERAMIA 2002, took place in Spain for the second time in 14 years; the first conference was organized in Barcelona in January 1988. The city of Seville hosted this 8th conference, giving the participants the opportunity of enjoying the richness of its historical and cultural atmosphere. Looking back over these 14 years, key aspects of the conference, such as its structure, organization, the quantity and quality of submissions, the publication policy, and the number of attendants, have significantly changed. Some data taken from IBERAMIA’88 and IBERAMIA 2002 may help to illustrate these changes. IBERAMIA’88 was planned as an initiative of three Ibero-American AI associations: the Spanish Association for AI (AEPIA), the Mexican Association for AI (SMIA), and the Portuguese Association for AI (APIA). The conference was organized by the AEPIA staff, including the AEPIA president, José Cuena, the secretary, Felisa Verdejo, and other members of the AEPIA board. The proceedings of IBERAMIA’88 contain 22 full papers grouped into six areas: knowledge representation and reasoning, learning, AI tools, expert systems, language, and vision. Papers were written in the native languages of the participants: Spanish, Portuguese, and Catalan. Twenty extended abstracts describing ongoing projects were also included in the proceedings.
Download or read book Nonlinear Dynamics and Pattern Formation in the Natural Environment written by A. Van Harten and published by Taylor & Francis. This book was released on 2022-09-16 with total page 350 pages. Available in PDF, EPUB and Kindle. Book excerpt: This Research Note aims to provide an insight into recent developments in the theory of pattern formation. In the last decade there has been considerable progress in this field, both from a theoretical and a practical point of view. Recent mathematical developments concern the study of the nonlinear stability of systems at near-critical conditions by an appropriate system of modulation equations. The complexity of the original problem can be reduced drastically by this approximation. Moreover, it provides unifying point of view for a wide range of problems. New applications of the theory arise in a multitude of scientific areas such as hydrodynamics, reaction-diffusion problems, oceanography, meteorology, combustion, geophysical and biological morphodynamics and semi-conductors.This book is intended to show the interactions between the mathematical theory of nonlinear dynamics and the study of pattern generating phenomena in the natural environment. There is an intimate relationship between new insights in the mathematical aspects of nonlinear pattern formation and the comprehension of such phenomena. Therefore there are two partly overlapping main themes: one in which the emphasis is on generally applicable mathematical theories and techniques and one in which the phenomenology of pattern evolution in various areas is discussed.The book comprises 19 contributions by experts in the field. Although the emphasis changes considerably from paper to paper, in each contribution the same two themes are present; all the authors have aimed to achieve a suitable balance between the mathematical theory and the physical phenomena.
Download or read book Design Principles for the Immune System and Other Distributed Autonomous Systems written by Lee A. Segel and published by Oxford University Press. This book was released on 2001-06-14 with total page 415 pages. Available in PDF, EPUB and Kindle. Book excerpt: Design Principles for the Immune System and Other Distributed Autonomous Systems is the first book to examine the inner workings of such a variety of distributed autonomous systems--from insect colonies to high level computer programs to the immune system. It offers insight into the fascinating world of these systems that emerge from the interactions of seemingly autonomous components and brings us up-to-date on the state of research in these areas. Using the immune system and certain aspects of its functions as a primary model, this book examines many of the most interesting and troubling questions posed by complex systems. How do systems choose the right set of agents to perform appropriate actions with appropriate intensities at appropriate times? How in the immune system, ant colonies and metabolic networks does the diffusion and binding of a large variety of chemicals to their receptors permit coordination of system action? What advantages drive the various systems to complexity, and by what mechanisms do the systems cope with the tendency toward unwieldiness and randomness of large complex systems?
Download or read book Mathematical Modeling of the Immune System in Homeostasis Infection and Disease written by Gennady Bocharov and published by Frontiers Media SA. This book was released on 2020-02-24 with total page 278 pages. Available in PDF, EPUB and Kindle. Book excerpt: The immune system provides the host organism with defense mechanisms against invading pathogens and tumor development and it plays an active role in tissue and organ regeneration. Deviations from the normal physiological functioning of the immune system can lead to the development of diseases with various pathologies including autoimmune diseases and cancer. Modern research in immunology is characterized by an unprecedented level of detail that has progressed towards viewing the immune system as numerous components that function together as a whole network. Currently, we are facing significant difficulties in analyzing the data being generated from high-throughput technologies for understanding immune system dynamics and functions, a problem known as the ‘curse of dimensionality’. As the mainstream research in mathematical immunology is based on low-resolution models, a fundamental question is how complex the mathematical models should be? To respond to this challenging issue, we advocate a hypothesis-driven approach to formulate and apply available mathematical modelling technologies for understanding the complexity of the immune system. Moreover, pure empirical analyses of immune system behavior and the system’s response to external perturbations can only produce a static description of the individual components of the immune system and the interactions between them. Shifting our view of the immune system from a static schematic perception to a dynamic multi-level system is a daunting task. It requires the development of appropriate mathematical methodologies for the holistic and quantitative analysis of multi-level molecular and cellular networks. Their coordinated behavior is dynamically controlled via distributed feedback and feedforward mechanisms which altogether orchestrate immune system functions. The molecular regulatory loops inherent to the immune system that mediate cellular behaviors, e.g. exhaustion, suppression, activation and tuning, can be analyzed using mathematical categories such as multi-stability, switches, ultra-sensitivity, distributed system, graph dynamics, or hierarchical control. GB is supported by the Russian Science Foundation (grant 18-11-00171). AM is also supported by grants from the Spanish Ministry of Economy, Industry and Competitiveness and FEDER grant no. SAF2016-75505-R, the “María de Maeztu” Programme for Units of Excellence in R&D (MDM-2014-0370) and the Russian Science Foundation (grant 18-11-00171).
Download or read book Designing More Than Human Smart Cities written by Senior Lecturer in Computer Science Sara Heitlinger and published by Oxford University Press. This book was released on 2024-09-04 with total page 353 pages. Available in PDF, EPUB and Kindle. Book excerpt: Drawing from existing theory, policy, practice and speculative design about how cities may evolve, the book illustrates key concepts using case studies that respond to the complex relationships between human and non-human others (such as animals and plants, as well as soil, rivers, data and sensors) in urban space.
Download or read book Artificial Immune Systems written by Leandro N. de Castro and published by Springer. This book was released on 2007-08-28 with total page 449 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book constitutes the refereed proceedings of the 6th International Conference on Artificial Immune Systems, ICARIS 2007, held in Santos, Brazil, August 2007. The papers are organized in topical sections on search and optimization, classification and clustering, anomaly detection and negative selection, robotics, control and electronics. Modeling papers, conceptual papers, and technical papers and general applications are also included.
Download or read book Advances in Artificial Life written by Wolfgang Banzhaf and published by Springer. This book was released on 2011-03-31 with total page 922 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book constitutes the refereed proceedings of the 7th European Conference on Artificial Life, ECAL 2003, held in Dortmund, Germany in September 2003. The 96 revised full papers presented were carefully reviewed and selected from more than 140 submissions. The papers are organized in topical sections on artificial chemistries, self-organization, and self-replication; artificial societies; cellular and neural systems; evolution and development; evolutionary and adaptive dynamics; languages and communication; methodologies and applications; and robotics and autonomous agents.
