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Download or read book Sleep and Aging written by Mark P. Mattson and published by Elsevier. This book was released on 2005-06-20 with total page 212 pages. Available in PDF, EPUB and Kindle. Book excerpt: Sleep and Aging provides a unique and timely collection of review articles that cover the gamut of basic and clinical aspects of sleep and the abnormalities in sleep associated with aging and neurological disorders that occur during aging. From the evolutionary basis of sleep and its normal functions in processes such as learning and memory, to considerations of the roles of sleep abnormalities in neurological disorders such as depression, Alzheimer's and Parkinson's diseases, the chapters are written by experts in the field. Several chapters focus on signalling pathways involved in sleep regulation and abnormalities in sleep, including those activated by serotonin and BDNF. Basic and clinical research on insomnia, sleep apnea and other disorders of sleep, are covered thus providing students and scientists at all levels with a valuable source of information to advance their understanding of this important topic in aging, biology and medicine. The circuits in the brain involved in sleep regulation, their neurochemistry, how they are altered in disorders of sleep and current clinical treatments of various sleep disorders are reviewed. The important role of sleep disturbances in neurodegenerative disorders is described and research in this particular area is leading to a better understanding of the relationships between synaptic plasticity, neuronal degeneration and the clinical manifestations of disorders such as Alzheimer's disease, Parkinson's disease and depression. This book is a must for scientists, as well as non-scientists, who are interested in the neurobiology of aging, sleep and neurodegenerative disorders.
Download or read book Sleep and Development written by Mona El-Sheikh and published by John Wiley & Sons. This book was released on 2015-03-09 with total page 0 pages. Available in PDF, EPUB and Kindle. Book excerpt: The growing multidisciplinary literature on sleep and development needs to be integrated to yield organizing principles and conceptual frameworks researchers can use to defi ne and measure key constructs. This Monograph has three major aims: to present contemporary conceptual and methodological issues that need to be considered to integrate knowledge of sleep and child development across multiple disciplines, and accelerate the pace and enhance the quality of research (Chapter II); to discuss various sleep methodologies including their advantages and disadvantages (Chapter III); and to provide examples of longitudinal studies, which are needed in this developing area of inquiry, that demonstrate linkages between various sleep parameters and child development across multiple domains (Chapters IV through X). Chapter I introduces the main objectives of the volume, highlights the importance of sleep for child development, and presents a guiding framework for understanding the multiple influences on child sleep. Chapter II summarizes the outcomes of an SRCD sponsored forum on sleep and development that included scholars from multiple disciplines and presents guiding recommendations for research priorities. Themes include biobehavioral mechanisms, family processes, and socio-cultural factors; in addition, open questions and best practices in research design and statistics are discussed. Chapter III presents various sleep assessment methodologies including their advantages and disadvantages. Empirical studies (Chapters IV through X) were solicited from researchers in the fi eld; have a longitudinal element in their designs; demonstrate linkages between various sleep parameters and other key developmental domains; and use objective assessments of sleep duration or quality of "typically" developing children. Chapter XI summarizes key aspects of the various studies presented in this monograph and provides directions for this trans-disciplinary area of research.
