Download or read book The Role of Thyroid Hormones in Vertebrate Development volume II written by Marco António Campinho and published by Frontiers Media SA. This book was released on 2024-04-26 with total page 155 pages. Available in PDF, EPUB and Kindle. Book excerpt: Thyroid hormones role in development was first suggested in the 18th century when a relationship between goiter and cretinism was found by F.E. Fodere. But it was Rudolf Virchow work in the late 19th century with thyroidectomized animals that clearly demonstrated that goiter led to cretinism. This opened the door to the understanding of TH action on vertebrate development. However given the relative ease by which cretinism could be treated simply by eating animal thyroid gland or iodine supplementation, research into the action of TH on vertebrate development has been lagging. This was further enhanced by the complex biology of TH where, after production in the gland, entry, activation and binding of the TH to cognate receptors in target cells is highly regulated. Nonetheless, new scientific advances and technologies are now providing tools to dissect the developmental role of TH on vertebrate development, both embryonic and post-natal. The post-natal role of TH in vertebrate development is long known from anuran studies but less evidences exist from other vertebrates. Recently, new evidences show that TH constitute key developmental signal in embryonic development of vertebrates, especially in neural development, from humans to fish. This new evidences are corroborating long-standing observations that infants from mothers with impaired TH physiology presented changes in mental and cognitive indexes. Nonetheless, given that TH constitute integrative physiological signals in vertebrates a new scenario is emerging whereas TH seem to be important in the development and maturation of most organ systems in vertebrates during their different life transitions
Download or read book The Role of Thyroid Hormones in Vertebrate Development written by Marco António Campinho and published by Frontiers Media SA. This book was released on 2020-01-24 with total page 213 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Download or read book The Endocrinology of Growth Development and Metabolism in Vertebrates written by Martin Schreibman and published by Academic Press. This book was released on 2012-12-02 with total page 620 pages. Available in PDF, EPUB and Kindle. Book excerpt: The Endocrinology of Growth, Development, and Metabolism in Vertebrates provides an overview of vertebrate endocrinology. This book aims to strengthen the bridge between medical and comparative endocrinologists by addressing the benefits that they can derive from this association. Organized into five parts encompassing 24 chapters, this volume starts with a discussion on the structure and biological function of growth hormone (GH) and prolactin (PRL) family. This book then explains the extrinsic, genetic, and humoral factors that influence animal growth, particularly in poikilotherms. This text also elaborates the environmental conditions that affect the growth of poikilotherms, including food availability, temperature, and photoperiod. Other chapters discuss how somatotropin affects the growth development in homeotherms, such as livestock species. The reader is also introduced to the metabolic actions of GH, which can be described in terms of short-lived insulin-like effects. Endocrinologists, molecular endocrinologists, biologists, molecular biologists, biochemists, researchers, and physicians will find this book extremely useful.
Download or read book Vertebrate Endocrinology written by David O. Norris and published by Academic Press. This book was released on 2013-05-04 with total page 599 pages. Available in PDF, EPUB and Kindle. Book excerpt: Vertebrate Endocrinology represents more than just a treatment of the endocrine system-it integrates hormones with other chemical bioregulatory agents not classically included with the endocrine system. It provides a complete overview of the endocrine system of vertebrates by first emphasizing the mammalian system as the basis of most terminology and understanding of endocrine mechanisms and then applies that to non-mammals. The serious reader will gain both an understanding of the intricate relationships among all of the body systems and their regulation by hormones and other bioregulators, but also a sense of their development through evolutionary time as well as the roles of hormones at different stages of an animal's life cycle. - Includes new full color format includes over 450 full color, completely redrawn image - Features a companion web site hosting all images from the book as PPT slides and .jpeg files - Presents completedly updated and revitalized content with new chapters, such as Endocrine Disrupters and Behavioral Endocrinology - Offers new clinical correlation vignettes throughout
Download or read book Hormones and Reproduction of Vertebrates Volume 2 written by David O. Norris and published by Elsevier. This book was released on 2024-07-17 with total page 318 pages. Available in PDF, EPUB and Kindle. Book excerpt: Hormones and Reproduction of Vertebrates, Volume 2: Amphibians is the second of five second-edition volumes representing a comprehensive and integrated overview of hormones and reproduction in fishes, amphibians, reptiles, birds, and mammals. The book includes coverage of endocrinology, neuroendocrinology, physiology, behavior, and anatomy of amphibian reproduction. It provides a broad treatment of the roles of pituitary, thyroid, adrenal, and gonadal hormones in all aspects of reproduction, as well as descriptions of major life history events. New to this edition is a concluding assessment of the effect of environmental influences on amphibians. Initial chapters in this book broadly examine sex determination, reproductive neuroendocrinology, stress, and hormonal regulation as it relates to male and female reproductive structure and function. Subsequent chapters examine hormones and reproduction of specific taxa, including anuran amphibians, urodeles, and gymnophionids. The book concludes with an examination of endocrine disruption of reproduction in amphibians. Hormones and Reproduction of Vertebrates, Volume 2: Amphibians is designed to provide a readable, coordinated description of reproductive basics in amphibians, as well as an introduction to the latest trends in reproductive research and a presentation of our understanding of reproductive events gained over the past decade. It may serve as a stand-alone reference for researchers and practitioners in the field of herpetology or as one of five coordinated references aligned to provide topical treatment across vertebrate taxa for researchers, practitioners, and students focused on vertebrate endocrinology. - Covers endocrinology, neuroendocrinology, physiology, behavior, anatomy, and development of amphibian reproduction - Includes pituitary, thyroid, adrenal, and gonadal hormones - Focuses on anuran, urodele, and gymnophiona amphibians - Provides new coverage on environmental disruption in amphibians
Download or read book Vertebrate Endocrinology written by David O. Norris and published by Elsevier. This book was released on 2006-11-27 with total page 573 pages. Available in PDF, EPUB and Kindle. Book excerpt: One of the only books to discuss all vertebrates, the fourth edition of Vertebrate Endocrinology has been completely reorganized and updated to explore the intricate mechanisms that control human physiology and behavior as well as that of other vertebrate animals. Perfect for students in endocrinology, zoology, biology and physiology, it allows readers to gain both an understanding of the intricate relationships among all of the body systems and their regulation by hormones and other bioregulators, but also a sense of their development through evolutionary time as well as the roles of hormones at different stages of an animal's life cycle. Chapters have been reorganized to more closely follow traditional classroom presentation and extensive suggested readings are included at the end of each chapter allowing the reader to obtain further information as well as connect concepts to the literature on which the book is based. For the first time, this edition features four-color illustrations. - Provides a complete overview of the endocrine system of vertebrates by first emphasizing the mammalian system as the basis of most terminology and understanding of endocrine mechanisms and then applies that to non-mammals - Introduces the reader to suitable concepts and explanation of jargon so that the reader will be able to delve directly into the primary literature on any endocrine-related topic with a background that will aid in their interpretation of new information - Revised and updated chapter on The Molecular Bases for Chemical Regulation that now includes more evolutionary data - Includes information on endocrine disrupting chemicals and their implications on the health of wildlife and humans
Download or read book Evolution and Development of Fishes written by Zerina Johanson and published by Cambridge University Press. This book was released on 2019-01-10 with total page 283 pages. Available in PDF, EPUB and Kindle. Book excerpt: World-class palaeontologists and biologists summarise the state-of-the-art on fish evolution and development.
Download or read book The Blood Cerebrospinal Fluid Barrier written by Wei Zheng and published by CRC Press. This book was released on 2005-03-30 with total page 668 pages. Available in PDF, EPUB and Kindle. Book excerpt: Despite the existence of two barrier systems in the brain, research over the last century has mostly focused on the blood-brain barrier rather than on the blood-CSF barrier. Today, there is a greater understanding of the function of the blood-CSF barrier and of the choroid plexus, a tissue that is the primary site of this barrier. With the growing number of studies that focus on the role of the blood-CSF barrier in CNS homeostasis and neurological disorders, a modern overview of the blood-CSF barrier is long overdue. The Blood-Cerebrospinal Fluid Barrier is exclusively devoted to the blood-CSF barrier. Internationally renowned experts discuss the most recent progress in the field of choroid plexus physiology and update our knowledge of the function of the blood-CSF barrier. The book begins with an overview of the development and morphology of the choroid plexus, and then covers various aspects of its function, such as the regulation of choroidal blood flow, ion transport, and the production and transport of polypeptides. Following an extensive section on the role of the choroid plexus in CNS disorders, the final section discusses in vitro, in vivo, and in situ models of the blood-CSF barrier. This unique book analyzes a wealth of new research on the proven and potential roles of the choroid plexus/blood-CSF barrier in the brain. It is a valuable resource that will foster future studies in neuroscience, pharmacology, and toxicology.
Download or read book Thyroid Hormone Metabolism written by Georg Hennemann and published by Marcel Dekker. This book was released on 1986 with total page 656 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Download or read book An Introduction to Neuroendocrinology written by Richard E. Brown and published by Cambridge University Press. This book was released on 1994-01-27 with total page 434 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book is designed as an introductory text in neuroendocrinology; the study of the interaction between the brain and endocrine system and the influence of this on behaviour. The endocrine glands, pituitary gland and hypothalamus and their interactions and hormones are discussed. The action of steroid and thyroid hormone receptors and the regulation of target cell response to hormones is examined. The function of neuropeptides is discussed with respect to the neuroendocrine system and behaviour. The neuroimmune system and lymphokines are described and the interaction between the neuroendocrine and neuroimmune systems discussed. Finally, methods for studying hormonal influences on behaviour are outlined. Each chapter has review and essay questions designed for advanced students and honours or graduate students with a background in neuroscience, respectively.
Download or read book Acute Phase Proteins Molecular Biology Biochemistry and Clinical Applications written by Andrzej Mackiewicz and published by CRC Press. This book was released on 2020-07-24 with total page 706 pages. Available in PDF, EPUB and Kindle. Book excerpt: Acute Phase Proteins covers all major aspects of acute phase proteins (APP) starting with molecular mechanisms regulating their synthesis and ending with their functional significance. The book features 36 chapters addressing such topics as acute phase response and the APP; major APP and their structure and functions; regulation of APP synthesis, the cytokines and hormones implicated in these processes, and molecular mechanisms involved; signal transduction of cytokines in hepatocytes and posttranscriptional processes; and quantitative and qualitative evaluation of APP in clinical practice. The book will be an important reference for immunologists, molecular biologists, cellular biologists, biochemists, and clinical chemists.
Download or read book OECD Guidelines for the Testing of Chemicals Section 2 Test No 231 Amphibian Metamorphosis Assay written by OECD and published by OECD Publishing. This book was released on 2009-09-08 with total page 33 pages. Available in PDF, EPUB and Kindle. Book excerpt: This Test Guideline describes an amphibian metamorphosis assay intended to screen substances which may interfere with the normal functioning of the hypothalamo-pituitary-thyroid axis. The assay was validated with the species Xenopus laevis, which is ...
Download or read book Hormones and Reproduction of Vertebrates Mammals written by and published by . This book was released on 2011 with total page pages. Available in PDF, EPUB and Kindle. Book excerpt:
Download or read book Animal Metamorphosis written by and published by Academic Press. This book was released on 2013-01-17 with total page 471 pages. Available in PDF, EPUB and Kindle. Book excerpt: This new volume of Current Topics in Developmental Biology covers recent progresses in our understanding of animal metamorphosis. Over a dozen of leading experts reviews studies ranging from morphological, molecular to genetic analyses of metamorphosis in a broad spectrum of animals, including insects, fish. Topics include molecular evolution in metamorphosis, the synthesis and function of hormones in regulating metamorphic timing and rate, regulation and function of nuclear hormone receptors, neuroendocrine control of metamorphosis, tissue specific metamorphic events such as autophagy and stem cell development, and applications of genome-wide analysis technologies for studying metamorphosis. - First comprehensive review of the metamorphosis in diverse animal species by leading experts in the field - Covers a broad range of subjects: from morphological changes, molecular and genetic studies, to cutting-edge technologies for metamorphic studies; from systematic changes to tissue specific events, such as autophagy and stem cell development, which are areas of enormous interest in contemporary biomedical research - Serves as a reference book for undergraduate and graduate students in fields across biology and biomedicine
Download or read book Health Impacts of Developmental Exposure to Environmental Chemicals written by Reiko Kishi and published by Springer Nature. This book was released on 2019-12-13 with total page 554 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book provides concise and cutting-edge studies on threats resulting from exposure to environmental chemicals that can affect human health and development, with a particular emphasis on the DOHaD concept. The book is divided into five main parts, the first of which includes an introduction to the impacts of developmental exposure to environmental chemicals and historical perspectives, while the second focuses on how environmental chemicals can affect human organs, including neurodevelopment, immune functions, etc. In turn, the third part addresses the characteristics of specific chemicals and their effects on human health and development, while the fourth part provides a basis for future studies by highlighting the latest innovations in toxicology, remaining challenges, and promising strategies in children’s environmental health research, as well as ideas on how to bridge the gap between research evidence and practical policymaking. The fifth and last part outlines further research directions and related policymaking aspects. Health Impacts of Developmental Exposure to Environmental Chemicals will appeal to young and veteran researchers, students, and physicians (especially gynecologists and pediatricians) who are seeking comprehensive information on how children’s health can be affected by harmful chemicals and other environmental toxicants.
Download or read book Hormones and Reproduction in Fishes Amphibians and Reptiles written by David O. Norris and published by Springer Science & Business Media. This book was released on 2012-12-06 with total page 627 pages. Available in PDF, EPUB and Kindle. Book excerpt: Comparative endocrinology is one of the most rapidly developing subdis ciplines within the field of endocrinology, and it is having a significant impact on research at the molecular, cellular, organisma1 and environmental levels. Much of the current ferment in endocrinology is in reproductive endocrinology. The purpose of this volume on hormones and reproduction in fishes, amphibians and reptiles is to summarize our present understandings and to identify important research problems to be addressed in the area of comparative reproductive endocrinology. It was inspired by the gathering at Copper Mountain, Colorado, of eminent endocrine scientists from around the world on the occasion of the Tenth International Symposium on Comparative Endocrinology in July, 1985. While preparing for that meeting, we decided that a special volume on reproductive endocrinology was needed to summarize what is known and to stimulate research in particular directions. Why do we emphasize fishes, amphibians and reptiles? First, knowledge about the reproductive endocrinology of these ectothermic vertebrates can provide a clearer picture of the evolution of reproductive hormones and their effects on target organs. This comparative approach can lead to new theories about the evolution of reproductive control mechanisms. Second, studies concerning the reproductive endocrinology of "lower" vertebrates can result in development of "model systems" for application to studies of birds and mammals. Indeed, information about the patterns of reproductive control in ectothermic vertebrates can tell us which are evolutionarily stable and which are labile.
Download or read book Amphibian Metamorphosis written by Yun-Bo Shi and published by Wiley-Liss. This book was released on 1999-10-18 with total page 292 pages. Available in PDF, EPUB and Kindle. Book excerpt: In an age when advanced molecular and genetic tools allow studies in various systems, amphibian metamorphosis still offers perhaps the most accessible model for the study of postembryonic organogenesis and mechanisms of hormonal regulation during vertebrate development. Amphibian Metamorphosis: From Morphology to Molecular Biology integrates findings from the most recent research with earlier observations, providing molecular and mechanistic insights into the signal transduction pathways underlying tissue-specific transformations during metamorphosis. The author, renowned expert of anuran metamorphosis and Head of the Unit of Molecular Morphogenesis at NICHD/NIH, begins with an overview of metamorphosis in different classes of amphibians and various factors that influence this process. A review of earlier morphological, cellular, and biochemical changes focuses on organs and tissues that have been studied extensively at the molecular level, while discussion of the thyroid hormone signal transduction pathway emphasizes transcriptional regulation mechanisms by thyroid receptors. The book provides a summary and comparison of gene regulation programs induced by thyroid hormone in several organs that undergo distinct metamorphic transformations. Several chapters are devoted to functional and mechanistic implications of the molecular findings on the thyroid hormone response genes in tissue transformation. Special features of this book include: * An emphasis on integrating the morphological approach with molecularand cell biology * A historical perspective on the progression from discovery of the thyroid hormone to present-day research advances * Comparisons of amphibian and insect metamorphosis * Dozens of instructive photographs, several in full color Amphibian Metamorphosis: From Morphology to Molecular Biology is a unique and invaluable resource for professionals and aspiring professionals in develop-mental biology, molecular biology, cell biology, evolutionary biology, and endocrinology.
