Download or read book The Role of Pharmacology in Pediatric Oncology written by D.G. Poplack and published by Springer Science & Business Media. This book was released on 2012-12-06 with total page 308 pages. Available in PDF, EPUB and Kindle. Book excerpt: The dramatic improvement made in recent years in the treatment of child hood malignancies has been in large part the result of advances in the field of pharmacology. Chemotherapy is the major therapeutic modality used to treat childhood cancer. Rational administration of antineoplastic chemo therapy to the child with cancer requires the pediatric oncologist to have a thorough understanding of the fundamental principles of clinical pharmaco logy, an intimate knowledge of the specific agents being used, and an aware ness of the unique biologic and physiologic features of children. In mid 1985, a distinguished group of pediatric oncologists and clinical pharmacologists convened in a unique workshop to review the subject of pharmacology in pediatric oncology. A goal of this workshop was to pro duce a book which would review this topic and present it in a format useful for the clinician. In this book basic principles of pharmacology, mechanisms of drug resis tance, new methods of drug delivery, guidelines for studying new agents in children, new biological response modifiers and the pharmacology of the most commonly used chemotherapeutic agents in children are reviewed in depth. Particular emphasis is given to discussing those topics which unique ly apply to the use of antineoplastic agents in children with cancer. The Editors VII Contents Preface . v Contents Vll List of Major Contributors Xl Principles of Antineoplastic Therapy in Children 1. Clinical pharmacokinetics for the pediatric oncologist ................ .
Download or read book Book Review of The Role of Pharmacology in Pediatric Oncology D written by R. Ertmann and published by . This book was released on 1988 with total page 1 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Download or read book Pediatric Oncologic Pharmacy written by Carolina Witchmichen Penteado Schmidt and published by Springer. This book was released on 2019-04-26 with total page 173 pages. Available in PDF, EPUB and Kindle. Book excerpt: There are few publications about chemotherapy in children, and none of them is a book aimed at pharmacists. Pediatric Oncology Pharmacy is an area where more and more specific knowledge is required in daily practice. Pharmacists who work in pediatric oncology area do not have a book directed at them; none of the oncopediatric books addresses topics unique to pharmacy — such as manipulation of cytotoxic drugs for children, analysis of oncopediatric prescriptions, clinical pharmacy in oncopediatrics, pharmaceutical care in oncopediatric area, and other subjects that are of exclusive interest to these professionals, but no less essential for a therapy of excellence. As for this need, the purpose of this book is to be a guideline for all subjects that pediatric oncology pharmacists need to know to work in this area. It will be an essential guide to pediatric oncology pharmacists, clinical pharmacists, pharmaceutical residents who work with drug therapy in children and pharmaceutical researchers. It will be a pocket guide to assist in daily practice, and it will be essential to Pediatric Oncology/ Hematology Institutions. The essential propose of this book is to be the first one focusing pediatric oncology for pharmacists.
Download or read book The Role of Clinical Pharmacology in Pediatric Oncology written by R. Riccardi and published by . This book was released on 1992* with total page 120 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Download or read book Drug Therapy and Interactions in Pediatric Oncology written by Carolina Witchmichen Penteado Schmidt and published by Springer. This book was released on 2016-10-21 with total page 223 pages. Available in PDF, EPUB and Kindle. Book excerpt: There are few publications about drug interactions in chemotherapy and even less about pediatric oncology treatment. For this reason, the present book is intended to offer guidelines about drug interactions for physicians, pharmacists and the other healthcare professionals involved in the chemotherapy of pediatric patients. In this book the reader will have access to a primary introduction for the major diseases in pediatric oncology, followed by the major therapeutic protocols. Following that, the most important drug interactions in pediatric oncology treatment are presented and discussed in detail. Finally, important topics such as Drug-Food Interactions are addressed. Drug Therapy and Interactions in Pediatric Oncology focuses in great detail on the drug interactions in Pediatric Oncohematology and will be an indispensable resource in daily practice for a wide range of health providers.
Download or read book Proceedings written by Joseph D. Borsi and published by . This book was released on 1989 with total page 132 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Download or read book The Role of Clinical Pharmacology in Pediatric Oncology written by R. Riccardi and published by . This book was released on 1992* with total page 176 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Download or read book The Role of Clinical Pharmacology in Pediatric Oncology written by International Society of Pediatric Oncology and published by . This book was released on 1992 with total page 120 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Download or read book Making Better Drugs for Children with Cancer written by National Research Council and published by National Academies Press. This book was released on 2005-03-31 with total page 56 pages. Available in PDF, EPUB and Kindle. Book excerpt: The successes that have been achieved in treating childhood cancers stand as beacons against the less dramatic improvements for adults with cancer. Progress began to accelerate in the 1960s and 1970s, as treatment regimens were built up, primarily by building combinations of chemotherapeutic drugs. However the near absence of research in pediatric cancer drug discovery threatens to halt the progress in childhood cancer treatment achieved during the past four decades. Making Better Drugs for Children with Cancer identifies the major issues to be addressed in developing new agents for childhood cancers, the gaps in research and development, and the steps that have been suggested to move the process forward. This report also makes a new proposal to capitalize on today's science to bring new treatments to children's cancers.
Download or read book Pediatric Drug Development written by Andrew E. Mulberg and published by John Wiley & Sons. This book was released on 2013-05-20 with total page 782 pages. Available in PDF, EPUB and Kindle. Book excerpt: Most medicines have never been adequately tested for safety and efficacy in pediatric populations and preterm, infants and children are particularly vulnerable to adverse drug reactions. Pediatric Drug Development: Concepts and Applications, Second Edition, addresses the unique challenges in conducting effective drug research and development in pediatric populations. This new edition covers the legal and ethical issues of consent and assent, the additional legal and safety protections for children, and the appropriate methods of surveillance and assessment for children of varying ages and maturity, particularly for patient reported outcomes. It includes new developments in biomarkers and surrogate endpoints, developmental pharmacology and other novel aspects of global pediatric drug development. It also encompasses the new regulatory initiatives across EU, US and ROW designed to encourage improved access to safe and effective medicines for children globally. From an international team of expert contributors Pediatric Drug Development: Concepts and Applications is the practical guide to all aspects of the research and development of safe and effective medicines for children.
Download or read book Pediatric Drug Research written by Marcia Crosse and published by DIANE Publishing. This book was released on 2007-08 with total page 62 pages. Available in PDF, EPUB and Kindle. Book excerpt: About 2/3 of drugs prescribed for children have not been studied & labeled for pediatric use, which places children at risk of being exposed to ineffective treatment or incorrect dosing. The Best Pharm. for Children Act (BPCA), encourages the mfrs. of drugs that still have marketing exclusivity to conduct pediatric drug studies (PDS), as requested by the FDA. If they do so, FDA may extend for 6 mo. the period during which no equivalent generic drugs can be marketed. This report: assessed the extent to which PDS were being conducted under BPCA for on-patent drugs; evaluated the impact of BPCA on labeling drugs for pediatric use & the process by which the labeling was changed; & illustrated the range of diseases treated by the drugs studied under BPCA.
Download or read book Chemotherapy in Neonates and Infants written by Carolina Witchmichen Penteado Schmidt and published by Springer. This book was released on 2018-04-12 with total page 198 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book provides a comprehensive overview of pediatric oncology, discussing drug therapy and treatment in children under the age of 1 year. It is the first volume to focus on chemotherapy in newborns and infants, especially the daily clinical practice and treatment protocols. Intended as a practical manual, it addresses all the major topics related to pediatric oncology in an accessible and easy-to-use format. It examines topics in pediatric oncology therapeutics, including drug metabolism, excretion, toxicity, drugs that can be used for each week or month of the patient’s life, dose adjustment and treatment protocols.Chemotherapy in Neonates and Infants focuses on the safe treatment of children in the first year of life, and is aimed at pediatric oncology/hematology institutions, clinics and departments. It is particularly valuable for researchers, pediatric oncology physicians, pediatric and neonatology physicians, oncology pharmacists and the other healthcare professionals directly involved in the chemotherapy of neonates and infants.
Download or read book Safe and Effective Medicines for Children written by Institute of Medicine and published by National Academies Press. This book was released on 2012-10-13 with total page 432 pages. Available in PDF, EPUB and Kindle. Book excerpt: The Best Pharmaceuticals for Children Act (BPCA) and the Pediatric Research Equity Act (PREA) were designed to encourage more pediatric studies of drugs used for children. The FDA asked the IOM to review aspects of pediatric studies and changes in product labeling that resulted from BPCA and PREA and their predecessor policies, as well as assess the incentives for pediatric studies of biologics and the extent to which biologics have been studied in children. The IOM committee concludes that these policies have helped provide clinicians who care for children with better information about the efficacy, safety, and appropriate prescribing of drugs. The IOM suggests that more can be done to increase knowledge about drugs used by children and thereby improve the clinical care, health, and well-being of the nation's children.
Download or read book Rational Therapeutics for Infants and Children written by Institute of Medicine and published by National Academies Press. This book was released on 2000-04-07 with total page 135 pages. Available in PDF, EPUB and Kindle. Book excerpt: The Institute of Medicine's (IOM's) Roundtable on Research and Development of Drugs, Biologics, and Medical Devices evolved from the Forum on Drug Development, which was established in 1986. Sponsor representatives and IOM determined the importance of maintaining a neutral setting for discussions regarding long-term and politically sensitive issues justified the need to revise and enhance past efforts. The new Roundtable is intended to be a mechanism by which a broad group of experts from the public* and private sectors can be convened to conduct a dialogue and exchange information related to the development of drugs, biologics, and medical devices. Members have expertise in clinical medicine, pediatrics, clinical pharmacology, health policy, health insurance, industrial management, and product development; and they represent interests that address all facets of public policy issues. From time to time, the Roundtable requests that a workshop be conducted for the purpose of exploring a specific topic in detail and obtaining the views of additional experts. The first workshop for the Roundtable was held on April 14 and 15, 1998, and was entitled Assuring Data Quality and Validity in Clinical Trials for Regulatory Decision Making. The summary on that workshop is available from IOM. This workshop summary covers the second workshop, which was held on May 24 and 25, 1999, and which was aimed at facilitating the development and proper use of drugs, biologics, and medical devices for infants and children. It explores the scientific underpinnings and clinical needs, as well as the regulatory, legal, and ethical issues, raised by this area of research and development.
Download or read book The role of clinical pharmacology written by Joseph D. Borsi and published by . This book was released on 1989 with total page 132 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Download or read book Mosby s Oncology Drug Reference written by Robert J. Ignoffo and published by Mosby. This book was released on 2007 with total page 0 pages. Available in PDF, EPUB and Kindle. Book excerpt: This convenient handbook gives you instant access to current, clinically relevant drug information. You'll find complete drug monographs for more than 100 drugs, plus separate units on pediatric oncology, supportive care, and drug interactions. In addition, special nursing considerations highlight your specific role and responsibility with respect to administration, patient monitoring, and patient education for each drug. A companion Evolve® website gives you quarterly updates, web links, formulas, and IV compatibilities. Full monographs provide crucial information you need for more than 100 of the most commonly used drugs in oncology practice and include Clinical Pharmocology, Safe Handling issues, Adverse Reactions, Unlabeled Uses, and Y-site Compatibles. Entire Pediatric Oncology unit focuses on considerations specific to pediatric patients. Supportive Care sections help you manage your patients' symptoms and side effects. Easy-to-use tables equip you with drug interactions for over 66 anticancer drugs. 13 preventive rules help you avoid medication errors. Occupational Exposures to Hazardous Drugs unit teaches you to assess risk, implement protective measures, and monitor hazardous agents. Color insert contains images of the pathophysiology of chemotherapy-induced emesis, oral mucosa and phases of mucositis, normal bone remodeling, and a cross-sectional diagram of vertebral column structures and corresponding metastases. Appendices provide you with quick reference for formulas, chemotherapy regimes and drug information on the web, patient assistance programs, and newly approved drugs in abbreviated monograph format. Flexible, water-resistant cover stands up to daily use on the job. Evolve Resources, free with qualified adoptions, include quarterly online updates with the latest information on newly approved drugs and indications, as well as commonly used formulas, IV compatibilities, and weblinks. PDA feature available with separate purchase allows you to download the entire handbook to a PDA device for easy-to-use navigation and search capability.
Download or read book Emergencies in Pediatric Oncology written by Asst. Prof. Katrin Scheinemann McMaster University Health Sciences and published by Springer. This book was released on 2011-12-02 with total page 185 pages. Available in PDF, EPUB and Kindle. Book excerpt: Pediatric oncology is a considerably complex discipline requiring frequent need for reference material. Emergencies in Pediatric Oncology meets this objective by serving as a concise, practical resource for the hurried physician. Replete with diagrams and written in a clear, succinct style, this title offers an easy-to-read guide especially useful for residents, fellows, and nurses. Providing an overview of the epidemiology of childhood cancer and the history of its treatment, this title also addresses a range of key problems in the pediatric oncologic setting, covering the most common emergencies and providing short, practical guidelines on how to handle them. Written by authorities from an array of disciplines, this helpful resource provides answers and concrete guidance and is a valuable contribution to the literature in pediatric oncology.
