Download or read book The Relationship Between Platelet vessel Wall Interaction Thrombosis and Atherosclerosis written by I. F. Lane and published by . This book was released on 1987 with total page pages. Available in PDF, EPUB and Kindle. Book excerpt:
Download or read book Platelet Vessel Wall Interactions written by R. Michael Pittilo and published by Springer Science & Business Media. This book was released on 2012-12-06 with total page 205 pages. Available in PDF, EPUB and Kindle. Book excerpt: The publication of Platelet-Vessel Wall Interactions, the second monograph in the Bloomsbury Series in Clinical Science, is particu larly welcome as its appearance signifies the further development of the Series and its potential for the future. The theme of this monograph is the pathophysiology of atherosclerosis, a topic that symbolises the aim of the Series, namely to highlight the important interfaces between basic medical science and clinical practice. Our congratulations to the Editors and contributors. London, December 1987 lack Tinker Preface In the Western world, atherosclerosis causes more illness and death than any other disease. Despite its devastating effects, the pathogenesis of the disease remains a matter for hypothesis and con jecture. This monograph owes its conception to a programme of work directed towards understanding the basic pathophysiology of atherosclerosis. The circulatory system is lined by vascular endothelium which has a central role in maintaining the integrity of the vessel wall and prevent ing thrombosis. The natural equilibrium existing between normal en dothelium which supports blood flow, and platelets which serve to re pair damaged endothelium, is explored in the first two chapters. Atherosclerosis developing as a response to endothelial injury is one hypothesis which has stimulated widespread interest, and re search has largely been directed towards finding the injurious agent.
Download or read book Platelet Vessel Wall Interactions written by R. Michael Pittilo and published by Springer. This book was released on 1988-02-26 with total page 198 pages. Available in PDF, EPUB and Kindle. Book excerpt: The publication of Platelet-Vessel Wall Interactions, the second monograph in the Bloomsbury Series in Clinical Science, is particu larly welcome as its appearance signifies the further development of the Series and its potential for the future. The theme of this monograph is the pathophysiology of atherosclerosis, a topic that symbolises the aim of the Series, namely to highlight the important interfaces between basic medical science and clinical practice. Our congratulations to the Editors and contributors. London, December 1987 lack Tinker Preface In the Western world, atherosclerosis causes more illness and death than any other disease. Despite its devastating effects, the pathogenesis of the disease remains a matter for hypothesis and con jecture. This monograph owes its conception to a programme of work directed towards understanding the basic pathophysiology of atherosclerosis. The circulatory system is lined by vascular endothelium which has a central role in maintaining the integrity of the vessel wall and prevent ing thrombosis. The natural equilibrium existing between normal en dothelium which supports blood flow, and platelets which serve to re pair damaged endothelium, is explored in the first two chapters. Atherosclerosis developing as a response to endothelial injury is one hypothesis which has stimulated widespread interest, and re search has largely been directed towards finding the injurious agent.
Download or read book Platelet Vessel Wall Interactions in Hemostasis and Thrombosis written by Rolando E. Rumbaut and published by Biota Publishing. This book was released on 2010-02-01 with total page 77 pages. Available in PDF, EPUB and Kindle. Book excerpt: Platelets are essential mediators of the physiologic process of hemostasis and pathologic thrombosis. While platelets do not interact with vascular walls under normal conditions, vascular injury or inflammation result in a coordinated series of events including platelet adhesion, aggregation, and promotion of coagulation. In this review, we describe the primary mechanisms involved in these responses in various vascular beds of both macro- and microvessels, and outline key unresolved aspects of these important interactions.
Download or read book Biology and Pathology of Platelet vessel Wall Interactions written by Georges Jolles and published by . This book was released on 1986 with total page 452 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Download or read book Platelets Thrombosis and the Vessel Wall written by Michael C Berndt and published by CRC Press. This book was released on 2003-09-02 with total page 471 pages. Available in PDF, EPUB and Kindle. Book excerpt: Platelets, Thrombosis and the Vessel Wall aims to highlight the key areas of platelet function in the regulation of haemostasis and thrombosis and covers areas such as platelet production, interaction of platelets with leucocytes, mechanisms of cross-talk between platelets, leukocytes, and endothelium. The two major clinical causes of thrombosis, anti-phospholipid antibodies and genetic predisposition, are also addressed.
Download or read book Platelet Vessel Wall Interactions in Hemostasis and Thrombosis written by and published by . This book was released on 2010 with total page pages. Available in PDF, EPUB and Kindle. Book excerpt: Platelets are essential mediators of the physiologic process of hemostasis and pathologic thrombosis. While platelets do not interact with vascular walls under normal conditions, vascular injury or inflammation result in a coordinated series of events including platelet adhesion, aggregation, and promotion of coagulation. In this review, we describe the primary mechanisms involved in these responses in various vascular beds of both macro- and microvessels, and outline key unresolved aspects of these important interactions. Table of Contents: Introduction / General Characteristics of Platelets
Download or read book Mechanisms of Vascular Disease written by Robert Fitridge and published by University of Adelaide Press. This book was released on 2011 with total page 589 pages. Available in PDF, EPUB and Kindle. Book excerpt: New updated edition first published with Cambridge University Press. This new edition includes 29 chapters on topics as diverse as pathophysiology of atherosclerosis, vascular haemodynamics, haemostasis, thrombophilia and post-amputation pain syndromes.
Download or read book Manual of Blood Platelets Morphology Physiology and Pharmacology written by Gundu HR Rao and published by Jaypee Brothers Medical Publishers. This book was released on 2018-11-30 with total page 283 pages. Available in PDF, EPUB and Kindle. Book excerpt: Platelets are tiny blood cells that help the body form clots to stop bleeding. Antiplatelet medications, such as aspirin and clopidogrel, are commonly used to thin the blood which limits clotting and reduces the risk of heart attack. This book is a comprehensive guide to blood platelets for haematologists. Beginning with discussion on platelet structure, morphology, function and physiology, the next chapters cover the role of calcium in platelet activation and calcium modulation by cyclic nucleotides. The following sections explain the pharmacology of antiplatelet drugs, antiplatelet therapies, aspirin resistance, and the association of diabetes mellitus with major platelet dysfunction. The book concludes with chapters on acute coronary problems, interaction between endothelial cells and platelets, and blood biocompatibility studies. Authored by a Minneapolis-based expert in the field, the text is further enhanced by clinical photographs, diagrams and tables. Key points Comprehensive guide to blood platelets for haematologists Extensive coverage of antiplatelet drugs and resistance Recognised author from University of Minnesota Highly illustrated with clinical photographs, diagrams and tables
Download or read book The Thrombotic Process in Atherogenesis written by A. B. Chandler and published by Springer Science & Business Media. This book was released on 2013-03-09 with total page 531 pages. Available in PDF, EPUB and Kindle. Book excerpt: Two infonnal meetings of consultants expert in hemostatic phenomena and in atherogenesis were held in Bethesda, Maryland, in December 1975 and February 1976 by the National Heart, Lung, and Blood Institute. Their purpose was to discuss the current status of knowledge concerning the thrombotic process in the pathogenesis of atherosclerosis. It was readily agreed that thrombosis often played a major role in plaque building and in plaque complication. It was also commented, however, that the data were qualitative in nature and that quantitative infonnation was remarkably sparse. The term thromboatherogenesis was thought to be appropriate for those phenomena in which the full expression of the thrombotic process is manifest. At the same time, recent research was noted in which what appears to be an important pathway for the initiation of atherogenesis arises from the reaction of platelets with injured arterial endothelium and'Subendothelium without necessarily involving the complete classical thrombotic process. A name was not coined for this circumstance, but it was held that thromboatherogenesis was not a fully appropriate one.
Download or read book The Platelet vessel Wall Interaction in Experimental Atherosclerosis and Ischaemic Heart Disease written by Steen Dalby Kristensen and published by . This book was released on 1992 with total page 23 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Download or read book Advances in Hemostasis and Thrombosis written by A. Cajozzo and published by Springer Science & Business Media. This book was released on 2013-11-27 with total page 330 pages. Available in PDF, EPUB and Kindle. Book excerpt: A greater knowledge of the basic molecular mechanisms which regulate platelet function, coagulation, the fibrinolytic system and their interaction with the vessel wall has allowed a better understanding of the numerous aspects involved in the pathogenesis of thrombosis and the regulation of hemostasis. Thrombosis represents today one of the causes of death in the Western hemisphere. Arterial thrombosis may lead to myocardial infarction, cerebral and peripheral vascular diseases. Venous thrombosis, on the other hand, is a complication of heart disease, surgery, extensive trauma, several obstetric pathologies, and may, at times, develop in apparently healthy subjects. These complex problems are dealt with within the content of "Advances in Hemostasis and Thrombosis." The present papers contain up-to-date information on hemostasis, the role of prostaglandins, fibrinolytic coagulation, rheology, and modern therapeutic approaches along with their clinical application. This book, therefore, offers the reader the opportunity to profit from a rare encounter, an interdisciplinary cooperation, with scientific contributions from numerous countries.
Download or read book Interaction of Platelets with the Vessel Wall written by John A. Oates and published by . This book was released on 1985 with total page 190 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Download or read book Antithrombotics written by A. G. Herman and published by Springer Science & Business Media. This book was released on 1991 with total page 280 pages. Available in PDF, EPUB and Kindle. Book excerpt: 1. Platelet activation and aggregation: rationale for combining antithrombotic drugs.- 2. Role of nitric oxide in endothelial cell - platelet interactions.- 3. Platelets and megakaryocytes in vascular disease.- 4. Thrombosis in relation to atherosclerosis.- 5. Pharmacological inhibition of the ADP-GP IIb/IIIa-fibrinogen pathway of platelet aggregation.- 6. Calcium fluxes in platelets and endothelial cells, mechanisms and functional significance.- 7. Inhibition of platelet function by cyclic nucleotides and cyclic nucleotide-dependent protein kinases.- 8. Pharmacological modification of platelet-derived cyclooxygenase product formation and its consequences for platelet-vessel wall interactions.- 9. Antithrombotics and the lipoxygenase pathway.- 10. Pathological expressions of platelet-vessel wall interactions: implications of serotonin.- 11. The involvement of PAF in thrombotic events.- 12. Prostaglandins and -analogs in the treatment of platelet-vessel wall interaction.- 13. Adjuvant agents to enhance and sustain reperfusion with t-PA: studies in experimental dog models.- 14. Effect of dietary marine lipids on (anti-)thrombotic mechanisms.
Download or read book The Endothelium written by Michel Félétou and published by Morgan & Claypool Publishers. This book was released on 2011 with total page 309 pages. Available in PDF, EPUB and Kindle. Book excerpt: The endothelium, a monolayer of endothelial cells, constitutes the inner cellular lining of the blood vessels (arteries, veins and capillaries) and the lymphatic system, and therefore is in direct contact with the blood/lymph and the circulating cells. The endothelium is a major player in the control of blood fluidity, platelet aggregation and vascular tone, a major actor in the regulation of immunology, inflammation and angiogenesis, and an important metabolizing and an endocrine organ. Endothelial cells controls vascular tone, and thereby blood flow, by synthesizing and releasing relaxing and contracting factors such as nitric oxide, metabolites of arachidonic acid via the cyclooxygenases, lipoxygenases and cytochrome P450 pathways, various peptides (endothelin, urotensin, CNP, adrenomedullin, etc.), adenosine, purines, reactive oxygen species and so on. Additionally, endothelial ectoenzymes are required steps in the generation of vasoactive hormones such as angiotensin II. An endothelial dysfunction linked to an imbalance in the synthesis and/or the release of these various endothelial factors may explain the initiation of cardiovascular pathologies (from hypertension to atherosclerosis) or their development and perpetuation. Table of Contents: Introduction / Multiple Functions of the Endothelial Cells / Calcium Signaling in Vascular Cells and Cell-to-Cell Communications / Endothelium-Dependent Regulation of Vascular Tone / Conclusion / References
Download or read book Platelets and Atherosclerosis written by Christoff Kessler and published by Springer. This book was released on 1991 with total page 132 pages. Available in PDF, EPUB and Kindle. Book excerpt: Most patients with cerebrovascular diseases are treated with antiplatelet drugs. Basic thromosis research showed that platelets are an important factor in the pathogenesis of ar- therosclerosis and its complications, but other compounds as macrophages and vessel wall factors are also involved in this process. The aim of this volume is to connect labora- tory findings with clinical applications.
Download or read book Blood Vessels written by S. Effert and published by Springer Science & Business Media. This book was released on 2012-12-06 with total page 176 pages. Available in PDF, EPUB and Kindle. Book excerpt:
