Download or read book The Gastrointestinal Circulation written by Peter R. Kvietys and published by Morgan & Claypool Publishers. This book was released on 2010 with total page 127 pages. Available in PDF, EPUB and Kindle. Book excerpt: The microcirculation of the gastrointestinal tract is under the control of both myogenic and metabolic regulatory systems. The myogenic mechanism contributes to basal vascular tone and the regulation of transmural pressure, while the metabolic mechanism is responsible for maintaining an appropriate balance between O2 demand and O2 delivery. In the postprandial state, hydrolytic products of food digestion elicit a hyperemia, which serves to meet the increased O2 demand of nutrient assimilation. Metabolically linked factors (e.g., tissue pO2, adenosine) are primarily responsible for this functional hyperemia. The fenestrated capillaries of the gastrointestinal mucosa are relatively permeable to small hydrolytic products of food digestion (e.g., glucose), yet restrict the transcapillary movement of larger molecules (e.g., albumin). This allows for the absorption of hydrolytic products of food digestion without compromising the oncotic pressure gradient governing transcapillary fluid movement and edema formation. The gastrointestinal microcirculation is also an important component of the mucosal defense system whose function is to prevent (and rapidly repair) inadvertent epithelial injury by potentially noxious constituents of chyme. Two pathological conditions in which the gastrointestinal circulation plays an important role are ischemia/reperfusion and chronic portal hypertension. Ischemia/reperfusion results in mucosal edema and disruption of the epithelium due, in part, to an inflammatory response (e.g., increase in capillary permeability to macromolecules and neutrophil infiltration). Chronic portal hypertension results in an increase in gastrointestinal blood flow due to an imbalance in vasodilator and vasoconstrictor influences on the microcirculation. Table of Contents: Introduction / Anatomy / Regulation of Vascular Tone and Oxygenation / Extrinsic Vasoregulation: Neural and Humoral / Postprandial Hyperemia / Transcapillary Solute Exchange / Transcapillary Fluid Exchange / Interaction of Capillary and Interstitial Forces / Gastrointestinal Circulation and Mucosal Defense / Gastrointestinal Circulation and Mucosal Pathology I: Ischemia/Reperfusion / Gastrointestinal Circulation and Mucosal Pathology II: Chronic Portal Hypertension / Summary and Conclusions / References / Author Biography

Download or read book Sherlock s Diseases of the Liver and Biliary System written by James S. Dooley and published by John Wiley & Sons. This book was released on 2018-08-06 with total page 832 pages. Available in PDF, EPUB and Kindle. Book excerpt: A new, fully updated edition of the world’s most famous book on liver diseases—with updating of all areas and inclusion of new specific topics, by internationally renowned specialists This brand new edition of the classic book on hepatology provides a concise, clearly presented and well-structured review across the whole spectrum of hepatobiliary diseases by some of the world’s leading hepatologists and hepatobiliary specialists. Where many other hepatology textbooks provide detailed accounts of basic science and clinical management, Sherlock's Diseases of the Liver and Biliary System, 13th Edition takes a different approach. Concentrating on the clinical decisions to be taken and the relevant supporting data, it is written and edited to maintain Sheila Sherlock's unique approach, in particular the clarity and layout of the text, and the explanatory figures and tables. The book is thus concise, highly accessible, and generously illustrated with over 700 attractive color figures. There is a pithy approach to each disease based both on evidence and on the authors’ experience, the hallmark of this book. Based on these elements, the 12th edition was awarded first prize in the 2012 British Medical Association Book Awards in the Internal Medicine category. Sherlock's Diseases of the Liver and Biliary System begins by introducing the anatomy and function of the liver to readers, continuing then with in-depth coverage of liver biopsy techniques and interpretation, and fibrogenesis and its assessment. There are then chapters on all aspects of liver and biliary disease including acute liver failure, cirrhosis, portal hypertension, hepatic encephalopathy, ascites, hepatitis B and C, alcohol and the liver, non-alcoholic fatty liver disease, drug related liver reactions, cholestatic, autoimmune and genetic liver diseases, benign and malignant tumours and not least liver transplantation. There are also chapters on the liver in pregnancy, in the neonate, infancy and childhood, in systemic diseases and in infections. This new edition also features four new individual chapters focusing on coagulation, non-invasive assessment of fibrosis and cirrhosis; vascular diseases of the liver and portal vein thrombosis, and nutrition in liver disease. Digital downloads of the figures from this edition are offered on a companion website. Internationally recognized and loved, world-renowned hepatology book, first published in 1955 Takes a one-of-a-kind, clinical approach maintaining Sheila Sherlock’s clarity and legacy of presentation Full colour throughout with 700 illustrative figures Wide faculty of international contributors Sherlock's Diseases of the Liver and Biliary System, 13th Edition is an ideal primer in hepatology for students and trainees in hepatology and gastroenterology, and a valuable resource for all specialist gastroenterologists and hepatologists, paediatricians, pathologists, radiologists, general physicians and specialist nurses.

Download or read book CURRENT Diagnosis and Treatment Surgery Thirteenth Edition written by Gerard Doherty and published by McGraw Hill Professional. This book was released on 2009-08-20 with total page 1328 pages. Available in PDF, EPUB and Kindle. Book excerpt: To-the-point information on more than 1000 diseases and disorders surgeons are most likely to encounter The leading single-source surgery book for house-staff, students, practitioners, and surgeons A Doody's Core Title for 2011! "This is an excellent source of updated, authoritative, and concise information on diseases encountered in general surgery and the surgical subspecialties of otolaryngology, urology, gynecology, orthopedics, plastic and reconstructive surgery, and pediatrics....This is a wonderful resource for all levels of surgical practitioners as well as nonsurgical practitioners. In my experience, it has provided me with a framework to prepare for both oral and written boards. 3 Stars."--Doody's Review Service Authoritative, concise, and completely up-to-date, CURRENT Diagnosis & Treatment Surgery features: Wide-ranging coverage that encompasses general surgery and all the important subspecialties including otolaryngology, urology, gynecology, orthopedics, plastic and reconstructive surgery, and pediatrics References linked to recent journal articles Logical quick-find organization made even more accessible by a comprehensive index More than 600 informative photographs and illustrations Detailed treatment algorithms NEW CD-ROM with content from Quick Answers: Surgery to speed diagnosis of symptoms and signs NEW Chapter on Training, Communication, Professionalism, and Systems-Based Practice Completely rewritten chapters on Wound Healing, Anesthesia, Otolaryngology/Head & Neck Surgery, The Heart, Neurosurgery, Gynecology, and Orthopedics

Download or read book Vascular Disorders of the Liver written by Dominique Valla and published by Springer Nature. This book was released on 2021-12-03 with total page 376 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book provides a comprehensive account on individually rare, but collectively frequent diseases of the liver. In the first part, conditions such as hepatic vascular malformations, ischemic cholangiopathy, hepatic artery occlusion, sinusoidal conditions and Budd-Chiari syndrome are discussed among others. The second part examines the causes of vascular liver disease namely, coagulation disorders, neoplasm disorders, non-malignant blood disorders, systemic diseases and toxins, among others. The unique expertise of the authors, who are all members of the Vascular Liver Disease Disorders Group, an independent network of researchers with a common interest in Vascular Liver Diseases, are merged for an optimal pragmatic and individualized approach. This book is of interest to a broad range of experts, such as hepatologists, internists, radiologists and angiologists.

Download or read book Anatomy for the FRCA written by James Bowness and published by Cambridge University Press. This book was released on 2019-07-11 with total page 183 pages. Available in PDF, EPUB and Kindle. Book excerpt: This practical, comprehensive anatomy book arms FRCA candidates with detailed, robust anatomical knowledge via a question-based approach.

Download or read book Hepatic Circulation written by W. Wayne Lautt and published by Morgan & Claypool Publishers. This book was released on 2009-11-17 with total page 174 pages. Available in PDF, EPUB and Kindle. Book excerpt: The Hepatic circulation is unique among vascular beds. The most obvious unique features include the dual vascular supply; the mechanism of intrinsic regulation of the hepatic artery (the hepatic arterial buffer response); the fact that portal blood flow, supplying two thirds of liver blood flow, is not controlled directly by the liver; the fact that 20% of the cardiac output rushes through the most vascularized organ in the body, driven by a pressure gradient of only a few millimeters of mercury; the extremely distensible capacitance and venous resistance sites; the unidirectional acinar blood flow that regulates parenchymal cell metabolic specialization; and the high concentration of macrophagic (Kupffer) cells filtering the blood. The liver is the only organ reported to have regional blood flow monitored by the autonomic nervous system. This mechanism, when dysfunctional, accounts for the hepatorenal syndrome and offers a mechanistic therapeutic target to treat this syndrome. The trigger for liver regeneration is dependent on hepatic hemodynamics so that chronic liver blood flow regulates liver cell mass. In severe liver disease, the whole body circulation is reorganized, by forming portacaval shunts, to accommodate the increased intrahepatic venous resistance. These shunts protect the venous drainage of the splanchnic organs but lead to loss of major regulatory roles of the liver. The development of knowledge of the hepatic vasculature is presented from a historical perspective with modern concepts summarized based on the perspective of the author's four decades of devotion to this most marvelous of organs. Table of Contents: Acknowledgements / Historical Perspectives / Overview / Fluid Exchange / Capacitance / Resistance in the Hepatic Artery / Resistance in the Venous System / Fetal and Neonatal Hepatic Circulation / In Vivo Pharmacodynamic Approaches / Nitric Oxide / Adenosine / Hepatic Nerves / Hepatic Circulation and Toxicology / Hepatorenal Syndrome / Integrative Hepatic Response to Hemorrhage / Blood Flow Regulation of Hepatocyte Proliferation / Multiple Mechanisms Maintaining a Constant Hepatic Blood Flow to Liver Mass Ratio / Pathopharmacology and Repurposing Drugs as a Research Strategy / References

Download or read book Body MDCT in Small Animals written by Giovanna Bertolini and published by Springer. This book was released on 2017-09-05 with total page 443 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book is an up-to-date, technically detailed yet easy-to-read reference book on current clinical applications of MDCT in small animals. It has been designed to serve as the reference book for all MDCT-users, such as veterinary radiologists, imaging technicians, oncologists, surgeons, and non-radiologist clinicians. Individual chapters on novel clinically important topics include applications in endocrinology, oncology, trauma, and cardiovascular CT, as well as sections on organ-specific pathologies and their CT characteristics. The book will also cover main domains of CT, such as thorax and the trauma imaging. Anatomy, clinical aspects, pathology, and CT signs are integrated to provide the reader with the basis for interpretation of MDCT findings. Many excellent 2D multiplanar and 3D figures illustrating typical CT findings of various conditions will serve as a clinical reference for the reader.

Download or read book Spiral and Multislice Computed Tomography of the Body written by Mathias Prokop and published by Thieme. This book was released on 2011-01-01 with total page 1892 pages. Available in PDF, EPUB and Kindle. Book excerpt: Whole body computed tomography has developed at a rapid pace in the past decade, spurred on by the introduction of spiral and multislice scanning. These new technologies have not only improved diagnostic accuracy, but also made new applications possible that were previously accessible only through more complex or invasive techniques.This new book expertly fills a gap in the literature by combining the practically relevant technical background with the clinical information required for correctly performing and interpreting CT examinations. The book presents the state-of-the-art capabilities and requirements of CT as a key diagnostic and interventional tool, with special emphasis on the role of spiral and multi-slice CT. You will find a thorough introduction to CT technology from scanner design to 3D image reconstruction, useful practical hints on how to optimize your examination protocols and how to keep the radiation exposure of your patients to a minimum, as well as an extensive clinical section in which symptoms, pathology and CT morphology are integrated to provide you withthe basis for subtle interpretation of CT findings using the most modern CT techniques.Highlights include:- Full coverage of single-slice, 4-slice and 16-slice scanning techniques- Introduction to extended CT applications including cardiac CT,CT fluoroscopy,and 3D image processing- Organ-specific protocols for scanning and contrast administration- Practical guidelines for maximizing image quality and minimizing radiation exposure- Useful suggestions for image interpretation and for avoiding pitfalls and errors- Convenient format by organ systemand disease entity- Full discussion of organ-specific pathology and CT morphology- CT indications integrated with other imaging modalitiesAt a time when CT examinations are becoming more technically demanding and complex, with an increasing number of scan parameters and advances in 3D reconstructions, this book is an essential professional tool. Experienced practitioners will find their diagnostic and technical skills improved by reading the book, and beginners will enjoy the clear, systematic approach that will help them use the technique with confidence.

Download or read book Handbook of Pediatric Surgery written by Chandrasen K. Sinha and published by Springer Science & Business Media. This book was released on 2010-06-25 with total page 464 pages. Available in PDF, EPUB and Kindle. Book excerpt: Although pediatric surgery is a distinct and evolving specialty, it still remains an integral part of most general surgical and paediatric medical practice. Nevertheless, surgery in children does differ from adult practice in various fundamental ways, and there are key physiological and anatomical differences that constantly need underlining. Progress and improvement in outcome has also been rapid but it is sometimes difficult for practitioners to keep themselves up-to-date with the usual surgical or paediatric text books. This book will give a concise overview of all important topics and is designed to provide information in order to recognise the common surgical conditions; namely typical symptoms and signs, investigation and then treatment management. It will also provide an anatomical and physiological background to aid understanding, in addition to emphasising logical, and where possible, evidence-based practice by the use of flow charts, tables and algorithms. Authored by an international range of leading contributors, this is the first book of its kind to offer comprehensive coverage to this topic in a quick reference, pocket-book format.

Download or read book Emergency Radiology written by Hani H. Abujudeh and published by Oxford University Press. This book was released on 2016 with total page 433 pages. Available in PDF, EPUB and Kindle. Book excerpt: Emergency Radiology presents a comprehensive review of emergency pathologies commonly encountered by practicing radiologists and residents in training. This book offers a guided approach to imaging diagnosis with examples of all imaging modalities complimented by the basics of interpretation and technique and the nuances necessary to arrive at the best diagnosis.

Download or read book Atlas of Critical Care Echocardiography written by Alexis Salerno and published by Springer Nature. This book was released on 2022-01-28 with total page 192 pages. Available in PDF, EPUB and Kindle. Book excerpt: This atlas covers the basics of ultrasound physics, provides the necessary background to successfully perform TEE and TTE procedures, and provides tips and tricks that will prove invaluable in the critical care environment. It also features an abundance of high quality photographs, illustrations and videos as well as numerous case studies to test the reader's ability to apply knowledge to real-life clinical situations. Written by experts in the field, The Atlas of Critical Care Echocardiography is a concise, visual guide designed for use by all physicians who see cardiac patients in the ICU.

Download or read book Biomarkers in Liver Disease written by Victor R. Preedy and published by Springer. This book was released on 2017-07-14 with total page 0 pages. Available in PDF, EPUB and Kindle. Book excerpt: In the past decade there has been a major sea change in the way disease is diagnosed and investigated due to the advent of high throughput technologies, such as microarrays, lab on a chip, proteomics, genomics, lipomics, metabolomics etc. These advances have enabled the discovery of new and novel markers of disease relating to autoimmune disorders, cancers, endocrine diseases, genetic disorders, sensory damage, intestinal diseases etc. In many instances these developments have gone hand in hand with the discovery of biomarkers elucidated via traditional or conventional methods, such as histopathology or clinical biochemistry. Together with microprocessor-based data analysis, advanced statistics and bioinformatics these markers have been used to identify individuals with active disease or pathology as well as those who are refractory or have distinguishing pathologies. New analytical methods that have been used to identify markers of disease and is suggested that there may be as many as 40 different platforms. Unfortunately techniques and methods have not been readily transferable to other disease states and sometimes diagnosis still relies on single analytes rather than a cohort of markers. There is thus a demand for a comprehensive and focused evidenced-based text and scientific literature that addresses these issues. Hence the formulation of Biomarkers in Disease The series covers a wide number of areas including for example, nutrition, cancer, endocrinology, cardiology, addictions, immunology, birth defects, genetics, and so on. The chapters are written by national or international experts and specialists.

Download or read book Hepatobiliary Diseases written by Jesus Prieto and published by Springer Science & Business Media. This book was released on 2012-12-06 with total page 1132 pages. Available in PDF, EPUB and Kindle. Book excerpt: The last few years have witnessed major developments in molecular biology which have had a significant impact on biomedical knowledge. As a result new concepts in cell biology have emerged, new etiologic agents have been discovered, and new drugs have become available. Furthermore, the world of mediators, cytokines, and humoral factors has enlarged considerably in a relatively short period and this has modified our views of diverse physio pathologic processes as well as opened up new therapeutic prospects. In addition, recent technologic advances have revolutionized our diagnostic methodology and have greatly enhanced the power of our therapeutic resources. All these factors have contributed to a substantial remodeling of both liver science and clinical hepatology, and these changes have generated the motivation for the production of the present book, which attempts to give an account of well-known clinical facts in the light of current thinking. It is the fruit of the coordinated work of experts from different countries in three continents. In a sense, it is a manifestation of the fact that inter national cooperation is becoming increasingly important not only in the expansion of science but also in its exposition. We hope that Hepatobiliary Diseases will be useful to both students and clinicians and that internists, gastroenterologists, and general practitioners will find in its contents a satifactory coverage of their field of interest.

Download or read book The Portal Venous System written by Charles Marks and published by Charles C. Thomas Publisher. This book was released on 1973 with total page 162 pages. Available in PDF, EPUB and Kindle. Book excerpt:

Download or read book Cognitive Pearls in General Surgery written by Vijay K. Maker and published by Springer. This book was released on 2014-12-02 with total page 469 pages. Available in PDF, EPUB and Kindle. Book excerpt: This text is organized by organ system and the illustrations highlight surgical pearls borne of experience and polished by the study of pertinent references. Hand-drawn and illustrated figures show exact anatomical relationships as we see them in-vivo. A question/answer format augments the images to allow the reader to actively reflect on the topic and to appraise his/her knowledge in that area. The discussion sections strive to explain not only what the correct answer is, but also why the distractors are wrong, in order to motivate discussion and self-reflection. Cognitive Pearls in General Surgery details the explicit thought processes and associations that underlie the understanding of the topics at hand, with the intent of enhancing the fun and enjoyment that only an informed and well-grounded practice of surgery can provide.

Download or read book Portal Hypertension written by Plinio Rossi and published by Springer Science & Business Media. This book was released on 2012-12-06 with total page 360 pages. Available in PDF, EPUB and Kindle. Book excerpt: Portal hypertension is a relatively common condition, the complications of which are frequently life threatening. Patients with portal hypertension represent an important por tion of the daily clinical work of abdominal radiologists, gastroenterologists and abdominal surgeons. During the past two decades the development of new radiological devices and of new percutaneous image-guided treatment methods has resulted in fundamental changes in the clinical management of patients with portal hypertension. During the same period tremen dous progress was achieved in the visualization of the numerous morphological and func tional changes observed in patients with portal hypertension, due to the clinical introduc tion of the new cross-sectional imaging methods: ultrasonography, computed tomography and magnetic resonance imaging. I am very grateful to Prof. Plinio Rossi, an internationally recognized leader in the field of interventional radiology, for accepting the challenging task of compiling and presenting in a structured way the numerous facts and data that have become available during the past few years in this rapidly developing field. The editor has been inspired and successful in his selection of the impressive group of international experts that has contributed to many chapters of this volume.

Download or read book Variceal Bleeding written by David Westaby and published by . This book was released on 1982 with total page 280 pages. Available in PDF, EPUB and Kindle. Book excerpt: