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Book The Pituitary adrenocortical Function

Download or read book The Pituitary adrenocortical Function written by National Library of Medicine (U.S.) and published by . This book was released on 1950 with total page 388 pages. Available in PDF, EPUB and Kindle. Book excerpt:

Book The Pituitary adrenocortical Function

Download or read book The Pituitary adrenocortical Function written by Army Medical Library (U.S.) and published by . This book was released on 1950 with total page 384 pages. Available in PDF, EPUB and Kindle. Book excerpt:

Book The Pituitary adrenocortical function

Download or read book The Pituitary adrenocortical function written by Army Medical Library (U.S.). and published by . This book was released on 1950 with total page 392 pages. Available in PDF, EPUB and Kindle. Book excerpt:

Book Central Regulation of the Pituitary Adrenal Complex

Download or read book Central Regulation of the Pituitary Adrenal Complex written by E. V. Naumenko and published by Springer Science & Business Media. This book was released on 2013-03-09 with total page 200 pages. Available in PDF, EPUB and Kindle. Book excerpt: This monograph gives an up-to-date account of the original results of the author's research in the complex field of the central control over relationships which have become established in the course of evolution between the hypothalamus and the pituitary gland. The author has limited the scope of this research on logical grounds to the study of central chemically reactive structures in the regulation of the adrenal glands through the intermediary of the hypothalamo-hypophyseal system. Through the author's skill and expertise in the analysis of the extensive and sometimes complicated literature he has successfully undertaken a differential approach to the analysis of the concrete role of catecholamines, acetylcholine, and serotonin in relation to the endocrine system. The vast range of experimental investigations and results of clinical observations published in the last few decades have revealed the humoral neurosecretory factors of the hypothalamus as impor tant regulators of the princ ipal functions of the pituitary gland and, through it, of the cyclic activity of the peripheral group of endocrine glands. Until recently the region of the cascade of regulatory in fluences preceding the hypothalamus was terra incognita. It is for this reason that Evgenii Vladimirovich Naumenko's monograph ac quires its special importance for the neurophysiologist, for its author has striven, by the use of experimental methods, to ascertain in detail the nature of influences which for a long time were in terpreted as the general dogmas of an abstract "nervism.

Book The Pituitary adrenocortical Function

Download or read book The Pituitary adrenocortical Function written by National Library of Medicine (U.S.) and published by . This book was released on 1950 with total page 0 pages. Available in PDF, EPUB and Kindle. Book excerpt:

Book The Hypothalamus Pituitary Adrenal Axis

Download or read book The Hypothalamus Pituitary Adrenal Axis written by and published by Elsevier. This book was released on 2008-09-12 with total page 413 pages. Available in PDF, EPUB and Kindle. Book excerpt: The hypothalamic-pituitary-adrenal axis controls reactions to stress and regulates various body processes such as digestion, the immune system, mood and sexuality, and energy usage. This volume focuses on the role it plays in the immune system and provides substantive experimental and clinical data to support current understanding in the field, and potential applications of this knowledge in the treatment of disease. Evidence presented in this book suggests that the nervous, endocrine, and immune systems form the Neuroendoimmune Supersystem, which integrates all the biological functions of higher organisms both in health and disease for their entire life cycle Contributors include both the scientists who initiated the work on the HPA axis and on the autonomic nervous system, and those who joined the field later

Book Effects of Complete Hypothalamic Deafferentation on the Regulation of Pituitary adrenocortical Function in the Rat

Download or read book Effects of Complete Hypothalamic Deafferentation on the Regulation of Pituitary adrenocortical Function in the Rat written by Richard Gregory Free and published by . This book was released on 1977 with total page 228 pages. Available in PDF, EPUB and Kindle. Book excerpt:

Book Adrenal Cortex

    Book Details:
  • Author : David C. Anderson
  • Publisher : Butterworth-Heinemann
  • Release : 1985
  • ISBN :
  • Pages : 316 pages

Download or read book Adrenal Cortex written by David C. Anderson and published by Butterworth-Heinemann. This book was released on 1985 with total page 316 pages. Available in PDF, EPUB and Kindle. Book excerpt: Adrenal Cortex presents a critical review of functional and structural zonation of the cortex. It discusses the regulation of adrenocortical function by control of growth and structure. It also addresses the adrenal cortex in the fetus and neonate. It demonstrates the cellular mechanisms involved in the acute and chronic actions of ACTH. Some of the topics covered in the book are the molecular structures of mineralocorticoid and glucocorticoid receptors; description of adrenarche and adrenal hirsutism; types of congenital enzymatic defects of the adrenal; aetiology and management of Cushing's ...

Book Hypothalamo pituitary adrenocortical Function in the Reserpine treated Rat

Download or read book Hypothalamo pituitary adrenocortical Function in the Reserpine treated Rat written by S. V. Vellucci and published by . This book was released on 1975 with total page pages. Available in PDF, EPUB and Kindle. Book excerpt:

Book Hypothalamic pituitary adrenocortical Regulation

Download or read book Hypothalamic pituitary adrenocortical Regulation written by Rolf Peter Zurbrügg and published by S. Karger AG (Switzerland). This book was released on 1976 with total page 96 pages. Available in PDF, EPUB and Kindle. Book excerpt:

Book ACTH Action in the Adrenal Cortex  From Molecular Biology to Pathophysiology

Download or read book ACTH Action in the Adrenal Cortex From Molecular Biology to Pathophysiology written by Nicole Gallo-Payet and published by Frontiers Media SA. This book was released on 2017-07-27 with total page 421 pages. Available in PDF, EPUB and Kindle. Book excerpt: By stimulating adrenal gland and corticosteroid synthesis, the adrenocorticotropic hormone (ACTH) plays a central role in response to stress. In this Research Topic, a particular attention has been given to the recent developments on adrenocortical zonation; the growth-promoting activities of ACTH; the various steps involved in acute and chronic regulation of steroid secretion by ACTH, including the effect of ACTH on circadian rhythms of glucocorticoid secretion. The Research Topic also reviews progress and challenges surrounding the properties of ACTH binding to the MC2 receptor (MC2R), including the importance of melanocortin-2 receptor accessory protein (MRAP) in MC2R expression and function, the various intracellular signaling cascades, which involve not only protein kinase A, the key mediator of ACTH action, but also phosphatases, phosphodiesterases, ion channels and the cytoskeleton. The importance of the proteins involved in the cell detoxification is also considered, in particular the effect that ACTH has on protection against reactive oxygen species generated during steroidogenesis. The impact of the cellular microenvironment, including local production of ACTH is discussed, both as an important factor in the maintenance of homeostasis, but also in pathological situations, such as severe inflammation. Finally, the Research Topic reviews the role that the pituitary-adrenal axis may have in the development of metabolic disorders. In addition to mutations or alterations of expression of genes encoding components of the steroidogenesis and signaling pathways, chronic stress and sleep disturbance are both associated with hyperactivity of the adrenal gland. A resulting effect is increased glucocorticoid secretion inducing food intake and weight gain, which, in turn, leads to insulin and leptin resistance. These aspects are described in detail in this Research Topic by key investigators in the field. Many of the aspects addressed in this Research Topic still represent a stimulus for future studies, their outcome aimed at providing evidence of the central position occupied by the adrenal cortex in many metabolic functions when its homeostasis is disrupted. An in-depth investigation of the mechanisms underlying these pathways will be invaluable in developing new therapeutic tools and strategies.

Book Genetic Diagnosis of Endocrine Disorders

Download or read book Genetic Diagnosis of Endocrine Disorders written by Roy E. Weiss and published by Academic Press. This book was released on 2015-10-09 with total page 462 pages. Available in PDF, EPUB and Kindle. Book excerpt: Genetic Diagnosis of Endocrine Disorders, Second Edition provides users with a comprehensive reference that is organized by endocrine grouping (i.e., thyroid, pancreas, parathyroid, pituitary, adrenal, and reproductive and bone), discussing the genetic and molecular basis for the diagnosis of various disorders. The book emphasizes the practical nature of diagnosing a disease, including which tests should be done for the diagnosis of diabetes mellitus in adults and children, which genes should be evaluated for subjects with congenital hypothyroidism, which genetic tests should be ordered in obese patients or for those with parathyroid carcinoma, and the rationale behind testing for multiple endocrine neoplasias. Offers a clear presentations of pharmacogenetics and the actual assays used in detecting endocrine diseases Teaches the essentials of the genetic basis of disease in each major endocrine organ system Offers expert advice from genetic counselors on how to use genetic information in counseling patients Includes new chapters on the genetics of lipid disorders and glycogen storage diseases, genetics of hypoglycemia, and whole genome/exome sequencing

Book Glucocorticoid Action

Download or read book Glucocorticoid Action written by Tomoshige Kino and published by . This book was released on 2004 with total page 248 pages. Available in PDF, EPUB and Kindle. Book excerpt: Glucocorticoids regulate multiple metabolic and developmental processes and play a vital role in the maintenance of basal and stress-related homeostasis. For the last 50 years, pharmacologic doses of glucocorticoids have been used in the treatment of inflammatory, autoimmune, and lymphoproliferative diseases and in the prevention of allograft rejection, while substitution doses have been employed in the management of adrenocortical insufficiency. aspects of glucocorticoid action, in particular, (i) the impact of maternal and early life stress on stress-related gene regulation in the offspring; (ii) the importance of glucocorticoids and their receptors; (iii) further understanding of the mechanisms of GR action, including its effect on chromatin modulation, its interaction with coactivators and corepressors, and the genetic dissection of GR function in mice; (iv) The interaction of hGR with other transcription factors, such as NF-kappa-B, p53, transforming growth factor beta (TGF-beta) and the chicken ovalbumin upstream promoter transcription factor II (COUP-TFII); recycling, ubiquitination and degradation of the receptor, actions of the GR-beta isoform, a novel synthetic nonsteroidal target gene-specific agonist, the importance of target tissue activity of 11-beta-hydroxysteroid dehydrogenase type 1 in glucocorticoid action in health and disease, the interaction of the receptor with the nutrient carnitine, the anthrax products protective antigen (PA) and lethal factor (LF), and the human immunodeficiency virus type-1 (HIV-1)-encoded molecules Vpr and Tat; (vi) an update on the effects of glucocorticoids on the immune system; and (vii) the clinical implications of glucocorticoid action, including glucocorticoid resistance/hypersensitivity, familial and sporadic glucocorticoid resistance, and the effects of stress and depression.