Download or read book The Pipeline and the Paradigm written by Samuel Avery and published by . This book was released on 2013 with total page 225 pages. Available in PDF, EPUB and Kindle. Book excerpt: Explores the political, social, economic, and ecological issues that underlie the Keystone XL pipeline project, an endeavor that would release enough carbon into the atmosphere to drastically hasten climate change.
Download or read book Attitude Change and the Bogus Pipeline Paradigm written by Steven P. Gunn and published by . This book was released on 1973 with total page 138 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Download or read book Clinical Trials written by Steven Piantadosi and published by John Wiley & Sons. This book was released on 2017-10-09 with total page 918 pages. Available in PDF, EPUB and Kindle. Book excerpt: Presents elements of clinical trial methods that are essential in planning, designing, conducting, analyzing, and interpreting clinical trials with the goal of improving the evidence derived from these important studies This Third Edition builds on the text’s reputation as a straightforward, detailed, and authoritative presentation of quantitative methods for clinical trials. Readers will encounter the principles of design for various types of clinical trials, and are then skillfully guided through the complete process of planning the experiment, assembling a study cohort, assessing data, and reporting results. Throughout the process, the author alerts readers to problems that may arise during the course of the trial and provides common sense solutions. All stages of therapeutic development are discussed in detail, and the methods are not restricted to a single clinical application area. The authors bases current revisions and updates on his own experience, classroom instruction, and feedback from teachers and medical and statistical professionals involved in clinical trials. The Third Edition greatly expands its coverage, ranging from statistical principles to new and provocative topics, including alternative medicine and ethics, middle development, comparative studies, and adaptive designs. At the same time, it offers more pragmatic advice for issues such as selecting outcomes, sample size, analysis, reporting, and handling allegations of misconduct. Readers familiar with the First and Second Editions will discover revamped exercise sets; an updated and extensive reference section; new material on endpoints and the developmental pipeline, among others; and revisions of numerous sections. In addition, this book: • Features accessible and broad coverage of statistical design methods—the crucial building blocks of clinical trials and medical research -- now complete with new chapters on overall development, middle development, comparative studies, and adaptive designs • Teaches readers to design clinical trials that produce valid qualitative results backed by rigorous statistical methods • Contains an introduction and summary in each chapter to reinforce key points • Includes discussion questions to stimulate critical thinking and help readers understand how they can apply their newfound knowledge • Provides extensive references to direct readers to the most recent literature, and there are numerous new or revised exercises throughout the book Clinical Trials: A Methodologic Perspective, Third Edition is a textbook accessible to advanced undergraduate students in the quantitative sciences, graduate students in public health and the life sciences, physicians training in clinical research methods, and biostatisticians and epidemiologists. This book is accompanied by downloadable files available below under the DOWNLOADS tab. These files include: MATHEMATICA program – A set of downloadable files that tracks the chapters, containing code pertaining to each. SAS PROGRAMS and DATA FILES used in the book. The following software programs, included in the downloadables, were developed by the author, Steven Piantadosi, M.D., Ph.D: RANDOMIZATION – This program generates treatment assignments for a clinical trial using blocked stratified randomization. CRM – Implements the continual reassessment methods for dose finding clinical trials. OPTIMAL – Calculates two-stage optimal phase II designs using the Simon method. POWER – This is a power and sample size program for clinical trials. Executables for installing these programs can also be found at https://risccweb.csmc.edu/biostats/. Steven Piantadosi, MD, PhD, is the Phase One Foundation Distinguished Chair and Director of the Samuel Oschin Cancer Institute, and Professor of Medicine at Cedars-Sinai Medical Center in Los Angeles, California. Dr. Piantadosi is one of the world’s leading experts in the design and analysis of clinical trials for cancer research. He has taught clinical trials methods extensively in formal courses and short venues. He has advised numerous academic programs and collaborations nationally regarding clinical trial design and conduct, and has served on external advisory boards for the National Institutes of Health and other prominent cancer programs and centers. The author of more than 260 peer-reviewed scientific articles, Dr. Piantadosi has published extensively on research results, clinical applications, and trial methodology. While his papers have contributed to many areas of oncology, he has also collaborated on diverse studies outside oncology including lung disease and degenerative neurological disease.
Download or read book The Innovation Game written by Armelle Corre and published by Springer Science & Business Media. This book was released on 2006-06-15 with total page 219 pages. Available in PDF, EPUB and Kindle. Book excerpt: Provides first time integrated approach to R and D-project, -pipeline and -department management from a micro-, meso- and macroscopic view. Derives 21 easy and ready to apply rules for a better design and a superior control of R and D without losinf sight of high scientific standards.
Download or read book Drug and Biological Development written by Ronald Evens and published by Springer Science & Business Media. This book was released on 2007-08-18 with total page 394 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book offers a complete discussion of product development in the pharmaceutical and biotechnology industries from discovery, to product launch, through life cycle management. The book is organized for optimal usefulness in the education and training of health care professionals (MD, PharmD, PhD), at universities. The format is a set of figures, tables and lists, along with detailed narrative descriptions, including real-life examples, illustrations, controversies in industry, and references. The editors and authors of the book are industry and research experts in a variety of disciplines.
Download or read book Sinatra and Me written by Tony Oppedisano and published by Simon and Schuster. This book was released on 2022-06-28 with total page 320 pages. Available in PDF, EPUB and Kindle. Book excerpt: "An intimate, revealing portrait of Frank Sinatra-from the man closest to the famous singer during the last decade of his life. More than a hundred books have been written about legendary crooner and actor Frank Sinatra. Every detail of his life seems to captivate: his career, his romantic relationships, his personality, his businesses, his style. But a hard-to-pin-down quality has always clung to him-a certain elusiveness that emerges again and again in retrospective depictions. Until now. From Sinatra's closest confidant and an eventual member of his management team, Tony Oppedisano, comes an extraordinarily intimate look at the singing idol. Deep into the night, for more than two thousand nights, Frank and Tony would converse-about music, family, friends, great loves, achievements and successes, failures and disappointments, the lives they'd led, the lives they wished they'd led. In these full-disclosure conversations, Sinatra spoke of his close yet complex relationship with his father, his conflicts with record companies, his carousing in Vegas, his love affairs with some of the most beautiful women of his era, his triumphs on some of the world's biggest stages, his complicated relationships with his talented children, and, most important, his dedication to his craft. Toward the end, no one was closer to the singer than Oppedisano, who kept his own rooms at the Sinatra residences for many years, often brokered difficult conversations between family members, and held the superstar entertainer's hand when he drew his last breath. Featuring never-before-seen photos and offering startlingly fresh anecdotes and new revelations that center on some of the most famous people of the past fifty years-including Jackie Kennedy, Marilyn Monroe, Sam Giancana, Madonna, and Bono-Sinatra and Me pulls back the curtain to reveal a man whom history has, in many ways, gotten wrong"--
Download or read book Activism and the Fossil Fuel Industry written by Andrew Cheon and published by Routledge. This book was released on 2018-02-06 with total page 254 pages. Available in PDF, EPUB and Kindle. Book excerpt: In less than a decade, activism against the fossil fuel industry has exploded across the globe. While environmentalists used to focus on legislative goals, such as carbon emissions trading or renewable energy policies, today the most prominent activists directly attack the fossil fuel industry. This timely book offers a comprehensive evaluation of different types of activism, the success and impact of campaigns and activities, and suggestions as to ways forward. This book is the first systematic treatment of the anti-fossil fuel movement in the United States. An accessible and readable text, it is an essential reference for scholars, policymakers, activists, and citizens interested in climate change, fossil fuels, and environmental sustainability. The entire book or chapters from it can be used as required or supplementary material in various courses at the undergraduate and graduate level. As the book is not technically challenging but contains a comprehensive review of climate change, fossil fuels, and the literature on environmental activism, it can be used as an accessible introduction to the anti-fossil fuel campaign across disciplines.
Download or read book Mathematics Of Harmony As A New Interdisciplinary Direction And Golden Paradigm Of Modern Science Volume 2 Algorithmic Measurement Theory Fibonacci And Golden Arithmetic s And Ternary Mirror symmetrical Arithmetic written by Alexey Stakhov and published by World Scientific. This book was released on 2020-09-03 with total page 331 pages. Available in PDF, EPUB and Kindle. Book excerpt: Volume II is the second part of the 3-volume book Mathematics of Harmony as a New Interdisciplinary Direction and 'Golden' Paradigm of Modern Science. 'Mathematics of Harmony' rises in its origin to the 'harmonic ideas' of Pythagoras, Plato and Euclid, this 3-volume book aims to promote more deep understanding of ancient conception of the 'Universe Harmony,' the main conception of ancient Greek science, and implementation of this conception to modern science and education.This 3-volume book is a result of the authors' research in the field of Fibonacci numbers and the Golden Section and their applications. It provides a broad introduction to the fascinating and beautiful subject of the 'Mathematics of Harmony,' a new interdisciplinary direction of modern science. This direction has many unexpected applications in contemporary mathematics (a new approach to a history of mathematics, the generalized Fibonacci numbers and the generalized golden proportions, the generalized Binet's formulas), theoretical physics (new hyperbolic models of Nature) and computer science (algorithmic measurement theory, number systems with irrational bases, Fibonacci computers, ternary mirror-symmetrical arithmetic).The books are intended for a wide audience including mathematics teachers of high schools, students of colleges and universities and scientists in the field of mathematics, theoretical physics and computer science. The book may be used as an advanced textbook by graduate students and even ambitious undergraduates in mathematics and computer science.
Download or read book The IT4ITTM Standard Version 3 0 written by The Open Group and published by Van Haren. This book was released on 2022-12-14 with total page 297 pages. Available in PDF, EPUB and Kindle. Book excerpt: This publication is the specification of The Open Group IT4IT Standard, Version 3.0, a standard of The Open Group. It describes a reference architecture that can be used to manage the business of Information Technology (IT) and the associated end-to-end lifecycle management of Digital Products. It is intended to provide a prescriptive Target Architecture and clear guidance for the transformation of existing technology management practices for a faster, scalable, automated, and practical approach to deploying product-based investment models and providing an unprecedented level of operational control and measurable value. This foundational IT4IT Reference Architecture is independent of specific technologies, vendors, organization structures, process models, and methodologies. It can be mapped to any existing technology landscape. It is flexible enough to accommodate the continuing evolution of operational and management paradigms for technology. It addresses every Digital Product lifecycle phase from investment decision-making to end-of-life. The IT4IT Standard addresses a critical gap in the Digital Transformation toolkit: the need for a unifying architectural model that describes and connects the capabilities, value streams, functions, and operational data needed to manage a Digital Product Portfolio at scale. The IT4IT Standard provides an approach to making digital investment decisions and managing digital outcomes that is particularly useful for: • C-level executives responsible for Digital Transformation, as a top-down view of digital value creation • Product Managers and Product Marketing Managers whose portfolios include significant digital content, as a way to integrate marketing priorities with product delivery practices • Governance, risk, and compliance practitioners, as a guide to controlling a modern digital landscape • Enterprise and IT Architects, as a template for IT tool rationalization and for governing end-to-end technology management architectures • Technology buyers, as the basis for Requests for Information (RFIs) and Requests for Proposals (RFPs) and as a template for evaluating product completeness • Consultants and assessors, as a guide for evaluating current practice against a well-defined standard • Technology vendors, as a guide for product design and customer integrations • Technical support staff, as a guide for automating and scaling up support services to deal with modern technology deployment velocity
Download or read book A Radical Dissonance Theory written by Jean-Léon Beauvois and published by Taylor & Francis US. This book was released on 1996 with total page 196 pages. Available in PDF, EPUB and Kindle. Book excerpt: This analysis of dissonance theory and reduction studies the evolution of cognitive dissonance theory. It provides a review and a new interpretation of Festinger's original theory, adding to the theory by emphasizing the importance of the status of behaviour.
Download or read book Beyond Bias and Barriers written by Institute of Medicine and published by National Academies Press. This book was released on 2007-05-04 with total page 347 pages. Available in PDF, EPUB and Kindle. Book excerpt: The United States economy relies on the productivity, entrepreneurship, and creativity of its people. To maintain its scientific and engineering leadership amid increasing economic and educational globalization, the United States must aggressively pursue the innovative capacity of all its people—women and men. However, women face barriers to success in every field of science and engineering; obstacles that deprive the country of an important source of talent. Without a transformation of academic institutions to tackle such barriers, the future vitality of the U.S. research base and economy are in jeopardy. Beyond Bias and Barriers explains that eliminating gender bias in academia requires immediate overarching reform, including decisive action by university administrators, professional societies, federal funding agencies and foundations, government agencies, and Congress. If implemented and coordinated across public, private, and government sectors, the recommended actions will help to improve workplace environments for all employees while strengthening the foundations of America's competitiveness.
Download or read book Genetic Programming Theory and Practice XVI written by Wolfgang Banzhaf and published by Springer. This book was released on 2019-01-23 with total page 234 pages. Available in PDF, EPUB and Kindle. Book excerpt: These contributions, written by the foremost international researchers and practitioners of Genetic Programming (GP), explore the synergy between theoretical and empirical results on real-world problems, producing a comprehensive view of the state of the art in GP. Topics in this volume include: evolving developmental programs for neural networks solving multiple problems, tangled program, transfer learning and outlier detection using GP, program search for machine learning pipelines in reinforcement learning, automatic programming with GP, new variants of GP, like SignalGP, variants of lexicase selection, and symbolic regression and classification techniques. The volume includes several chapters on best practices and lessons learned from hands-on experience. Readers will discover large-scale, real-world applications of GP to a variety of problem domains via in-depth presentations of the latest and most significant results.
Download or read book Challenging the Innovation Paradigm written by Karl Erik Sveiby and published by Routledge. This book was released on 2012 with total page 288 pages. Available in PDF, EPUB and Kindle. Book excerpt: The book goes behind the innovation frenzy characterizing society today. It brings attention to the commercial waste, policy ineffectiveness and human suffering caused by the way corporations have executed and policy makers have regulated innovation. It emphasizes the unexploited opportunities of approaches that consider also long term and undesirable consequences of innovation.
Download or read book Data Mesh written by Zhamak Dehghani and published by "O'Reilly Media, Inc.". This book was released on 2022-03-08 with total page 387 pages. Available in PDF, EPUB and Kindle. Book excerpt: Many enterprises are investing in a next-generation data lake, hoping to democratize data at scale to provide business insights and ultimately make automated intelligent decisions. In this practical book, author Zhamak Dehghani reveals that, despite the time, money, and effort poured into them, data warehouses and data lakes fail when applied at the scale and speed of today's organizations. A distributed data mesh is a better choice. Dehghani guides architects, technical leaders, and decision makers on their journey from monolithic big data architecture to a sociotechnical paradigm that draws from modern distributed architecture. A data mesh considers domains as a first-class concern, applies platform thinking to create self-serve data infrastructure, treats data as a product, and introduces a federated and computational model of data governance. This book shows you why and how. Examine the current data landscape from the perspective of business and organizational needs, environmental challenges, and existing architectures Analyze the landscape's underlying characteristics and failure modes Get a complete introduction to data mesh principles and its constituents Learn how to design a data mesh architecture Move beyond a monolithic data lake to a distributed data mesh.
Download or read book Augmented Reality written by Andrew Yeh Ching Nee and published by BoD – Books on Demand. This book was released on 2011-12-09 with total page 284 pages. Available in PDF, EPUB and Kindle. Book excerpt: Augmented Reality (AR) is a natural development from virtual reality (VR), which was developed several decades earlier. AR complements VR in many ways. Due to the advantages of the user being able to see both the real and virtual objects simultaneously, AR is far more intuitive, but it's not completely detached from human factors and other restrictions. AR doesn't consume as much time and effort in the applications because it's not required to construct the entire virtual scene and the environment. In this book, several new and emerging application areas of AR are presented and divided into three sections. The first section contains applications in outdoor and mobile AR, such as construction, restoration, security and surveillance. The second section deals with AR in medical, biological, and human bodies. The third and final section contains a number of new and useful applications in daily living and learning.
Download or read book Restorative Justice in Urban Schools written by Anita Wadhwa and published by Routledge. This book was released on 2015-11-19 with total page 187 pages. Available in PDF, EPUB and Kindle. Book excerpt: The school-to-prison pipeline is often the path for marginalized students, particularly black males, who are three times as likely to be suspended as White students. This volume provides an ethnographic portrait of how educators can implement restorative justice to build positive school cultures and address disciplinary problems in a more corrective and less punitive manner. Looking at the school-to-prison pipeline in a historical context, it analyzes current issues facing schools and communities and ways that restorative justice can improve behavior and academic achievement. By practicing a critical restorative justice, educators can reduce the domino effect between suspension and incarceration and foster a more inclusive school climate.
Download or read book Natural Language Processing and Chinese Computing written by Fei Liu and published by Springer Nature. This book was released on 2023-11-08 with total page 885 pages. Available in PDF, EPUB and Kindle. Book excerpt: This three-volume set constitutes the refereed proceedings of the 12th National CCF Conference on Natural Language Processing and Chinese Computing, NLPCC 2023, held in Foshan, China, during October 12–15, 2023. The ____ regular papers included in these proceedings were carefully reviewed and selected from 478 submissions. They were organized in topical sections as follows: dialogue systems; fundamentals of NLP; information extraction and knowledge graph; machine learning for NLP; machine translation and multilinguality; multimodality and explainability; NLP applications and text mining; question answering; large language models; summarization and generation; student workshop; and evaluation workshop.
