Download or read book Leading Pharmaceutical Operational Excellence written by Thomas Friedli and published by Springer Science & Business Media. This book was released on 2013-11-26 with total page 536 pages. Available in PDF, EPUB and Kindle. Book excerpt: Achieving operational excellence is a challenge for the pharmaceutical industry, with many companies setting successful examples time and again. This book presents such leading practices for managing operational excellence throughout the pharmaceutical industry. Based on the St.Gallen OPEX Model the authors describe the current status of OPEX and the future challenges that have to be dealt with. The ample theoretical background is complemented hand-in-hand by case studies contributed by authors from leading pharmaceutical companies.
Download or read book The Pathway to Operational Excellence in the Pharmaceutical Industry written by Thomas Friedli and published by . This book was released on 2010 with total page 365 pages. Available in PDF, EPUB and Kindle. Book excerpt: Neue Technologien, sich wandelnde Geschäftsstrategien, Kostendruck auf Hersteller und Zulieferer, migrierende globale Wertschöpfungsketten sowie neue regulatorische Anforderungen sind die Herausforderungen der Pharmaindustrie. Um in allen Bereichen Exzellenz zu erreichen gilt es, den Fokus auf die Menschen zu richten. Sie planen, bewirken, verbessern und erfinden neue Strategien, erfahren, Systeme und Strukturen. Die Fähigkeit zur Überwindung der inneren Trägheit eines Unternehmens macht den Unterschied. Die höchsten FundE-Ausgaben verzeichneten die Unternehmen, die sich nicht weiter mit einem eingeführten und evaluierten Verfahren beschäftigten. Das beeinträchtigte Innovationen im Produkt- und Substanzbereich. Veränderungen werden an Geschwindigkeit und Umfang zunehmen. Hier setzt die Operational Excellence ein. Dies impliziert, das Herstellungspotenzial zu entwickeln, als Grundlage einzigartiger Geschäftsstrategien. Dazu erforderlich sind Exzellenz in Führung und Management, Methoden und Tools sowie Technologie und Innovation. Zielgruppen:- Pharmazeutische Industrie- Zulieferindustrie- Fachhochschulen / Universitäten- Beratungsunternehmen- Behörden.
Download or read book Achieving Business and Operational Excellence in the Pharmaceutical Industry written by Shonna Marie Coffey and published by . This book was released on 2008 with total page 114 pages. Available in PDF, EPUB and Kindle. Book excerpt: (Cont.) First, substantial improvement opportunities exist within current pharmaceutical manufacturing. Second, pharmaceutical companies must build operational efficiencies into manufacturing process design. Lastly, operational excellence cannot simply be attained through the implementation of an improvement toolkit.
Download or read book Operational Excellence in the Pharmaceutical Industry written by Thomas Friedli and published by . This book was released on 2006 with total page 190 pages. Available in PDF, EPUB and Kindle. Book excerpt: In dem Buch werden die Ergebnisse einer Benchmark-Studie zum Thema "Operational Excellence in der Pharmaindustrie", die von der Universität St. Gallen und der Arbeitsgemeinschaft für Pharmazeutische Verfahrenstechnik e. V. (APV) durchgeführt wurde, zusammengefaßt und ausgewertet. Über 100 Pharma-Produktionsstätten in mehr als 20 europäischen Ländern wurden im Rahmen der Studie hinsichtlich des Ist-Zustandes ihrer Produktionsperformance unter besonderer Berücksichtigung der Anforderungen des "Lean Managements" untersucht. Die Autoren geben eine detaillierte Übersicht über die Studienergebnisse und präsentieren einen umfangreichen Maßnahmenkatalog, mit dessen Hilfe eine Steigerung der Operational Excellence von Pharma-Produktionsanlagen erreicht werden kann. Die Ergebnisse von sieben beispielhaften Fallstudien, die besonders umfangreich analysiert wurden, sowie ein Ausblick auf die wesentlichen sich bereits abzeichnenden technologischen Weiterentwicklungen im Bereich Pharma-Produktion vermitteln dem Leser praxisnahes und hilfreiches Wissen, um Verbesserungspotentiale im eigenen betrieblichem Umfeld analysieren und umsetzen zu können. Führende Pharma-Experten aus den Bereichen Management sowie Forschung & Entwicklung haben dazu beigetragen, das Thema Operational Excellence erstmals aus Sicht der Pharmaindustrie umfassend zu behandeln. Zielgruppen:- Pharmazeutische Industrie- Auftragshersteller- Zulieferindustrie- Anlagenbau- Planungsunternehmen- Consulting-Unternehmen- Universitäten und Fachhochschulen- Behörden (Überwachungsämter).
Download or read book Operational Excellence in the Pharmaceutical Industry written by Daniel Bellm and published by . This book was released on 2015 with total page pages. Available in PDF, EPUB and Kindle. Book excerpt:
Download or read book Sustainable Implementation of Operational Excellence Initiatives written by Alexandra Ettlin and published by . This book was released on 2013 with total page pages. Available in PDF, EPUB and Kindle. Book excerpt: In order to fulfill the growing need for agility and flexibility and to handle increasing production complexity, pharmaceutical manufacturing's strategic importance has risen. However, many companies are just starting to discover the potential and benefits of Operational Excellence initiatives. This thesis has two main parts: a theoretical base, which analyzes the development of integrated production systems and explores their origins in post-war Japan, as well as discussion of OPEX initiative elements across the whole industry scale. The second section is comprised of an exhaustive operational excellence questionnaire focusing on OPEX initiatives within six globally active pharmaceutical companies. Every company surveyed was different; research and literature has not yet been able to provide an answer about the correct structure and the number of people within a company needed to sustainably implement an OPEX initiative. Making a fundamental effort to change company philosophy and empowering employees to realize their own and the company's full potential should be the long-term goal of a meaningful OPEX effort. This vision must then be translated into reality through structures within the organization: through middle managers, who serve as a crucial link between corporate and site level, project teams who are evaluated according to project targets and employees at all levels who are granted sufficient time and resources to fully support and sponsor the initiative in all of its stages. Finally, promising organizational success factors are visualized in an "OPEX implementation house" model.
Download or read book Quality as the Foundation for Excellence written by Christian Mänder and published by . This book was released on 2016 with total page 0 pages. Available in PDF, EPUB and Kindle. Book excerpt: The changes in production environment in today's pharmaceutical industry are a challenge for almost every pharmaceutical company. With the increase in the global demand of drugs through demographic change and the medicine demand of emerging countries, the required quantity of pharmaceuticals will increase significantly in upcoming years. The industry struggles with the dual problem of drug shortages - which have quadrupled in recent years - and an increasing number of drug recalls. In general, regulatory pressure and current regulatory changes are forcing the pharmaceutical industry to develop a stable quality oriented production system. Thus, in the increasingly complex environment of the pharmaceutical industry, companies need to take a closer look at their quality organisation in order to stabilise their internal production system and increase their flexibility and overall performance. Due to this need, the research focuses on the investigation of the interdependencies of quality and excellence to leverage the advantages of both. Operational Excellence (OPEX), as an initiative and lived as a philosophy, leads to a better performance, more efficient use of resources and continuous improvement. Quality management approaches have a positive impact on quality, innovation and the overall performance. Even though well-known excellence models include quality as basic element, the examples from practice show that the pharmaceutical industry discusses these aspects self-sufficiently. The divide of quality and excellence is not a conceptual problem but an industry-made challenge. Based on an extensive literature review, a statistical evaluation, a benchmarking and a qualitative case study analysis, the thesis designs a descriptive model that builds the basis to structure an internal quality management system for pharmaceutical companies, using a systemic approach combining quality and excellence. In addition, the thesis introduce.
Download or read book Pharmaceutical Operations Management written by Pankaj Mohan and published by McGraw-Hill Professional. This book was released on 2006-03-16 with total page 264 pages. Available in PDF, EPUB and Kindle. Book excerpt: Publisher's Note: Products purchased from Third Party sellers are not guaranteed by the publisher for quality, authenticity, or access to any online entitlements included with the product. This book brings together a winning team of international operations experts to set the framework for building a world-class manufacturing organization. Pharmaceutical Operations Management focuses on key concepts such as: Policy Execution, Risk Management, Supply chain modeling, Advance process control and Six Sigma for the pharmaceutical industry: critical techniques which will offset cost, increase efficiency and turn any manufacture into financial winner.
Download or read book Measuring Operational Excellence Performance written by Stephan Alexander Köhler and published by . This book was released on 2019 with total page pages. Available in PDF, EPUB and Kindle. Book excerpt: Operational Excellence (OPEX) has been recognized as a major driver for business performance. Despite the importance of an integrated approach to drive business performance, scholars and practitioners have primarily focused on OPEX in manufacturing to create sustainable success. However, in the pharmaceutical industry the quality control (QC) lab constitutes a major bottleneck in the value creation. In recent time OPEX in QC labs has gained increased interest as a driver of the performance of the organization that has been overlooked to date. Literature contributes with generic excellence models. However, scholars have neglected to show their application in the specific context of QC labs of this research. The diverse performance measurement literature emphasizes that the approach to operational performance depends on the unit of analysis and cannot be transferred one-to-one from other areas. Today, the empirical work from academia and practice that discusses OPEX performance in pharmaceutical QC labs from an integrated perspective is scarce. Accordingly, this thesis addresses the outlined gap of knowledge with a scientifically conceptualized, practically operationalized, unified, and integrated approach to measure OPEX performance in pharmaceutical QC labs. The research employs a mixed-methods approach combining quantitative and qualitative research. The resource-based view (RBV) constitutes the scientific basis framing the research at hand. The thesis comprises three research stages. First, OPEX performance in pharmaceutical QC labs is conceptualized and operationalized. This stage concludes in an operationalized performance measurement model (PMM). Additionally, this stage yields in research propositions and hypotheses for the subsequent research stage. Second, a quantitative analysis provides new insight into the relation between the model dimensions and OPEX performance in QC labs. In particular, it focuses on the relation.
Download or read book Global Manufacturing Management written by Thomas Friedli and published by Springer Nature. This book was released on 2021-09-28 with total page 363 pages. Available in PDF, EPUB and Kindle. Book excerpt: Using site-specific optimization approaches in international manufacturing networks is increasingly proving insufficient. To solve this problem, several holistic and integrated alternatives have been developed to reflect a global perspective. This book presents advances in the St. Gallen Global Manufacturing Network Model and its application in numerous industry-, benchmarking- and research projects. The contents combine data-driven solutions with qualitative management frameworks for the strategic optimization of international manufacturing networks. In the first part, the book addresses the foundation of manufacturing network management and further describes the St. Gallen Operational Excellence approaches to manage plant performance. On this basis, the authors show how plant- and network-level performance can be enhanced via key improvement domains (e.g., strategy, configuration, coordination, performance management, digitalization). In turn, the second part demonstrates the application of the constructs in manufacturing companies from various industries. By combining research and practice, the book offers unique perspectives on the management of global production striving toward higher performance on manufacturing site and network level.
Download or read book PHARMA FACTORY in search of excellence written by P K Gondi and published by Clever Fox Publishing. This book was released on 2023-04-10 with total page 114 pages. Available in PDF, EPUB and Kindle. Book excerpt: A fictional story of introspection on raising standards of a pharmaceutical plant. A story of a pharma plant shifting from compliance to excellence. A compilation of instigative thoughts on operational excellence in pharma manufacturing
Download or read book Impacting Shop Floor Behavior in the Context of Pharmaceutical Operational Excellence Programs written by Lars-Julian Macuvele and published by . This book was released on 2022 with total page 0 pages. Available in PDF, EPUB and Kindle. Book excerpt: The management of shop floor behavior plays a critical role for the success of operational improvement programs, which rely on the workers that perform the direct value creation tasks. But what precisely should managers do to influence that behavior constructively? In the corresponding stream of Operational Excellence (OPEX) literature, this question has recently experienced an increase in research interest. For pharmaceutical manufacturers, addressing this question can be considered mission critical for two main reasons. First, OPEX programs are viewed as an antidote for low quality levels in pharmaceutical manufacturing, which are significantly lower compared to other industries. Second, procedural regulation can affect what behaviors are deemed acceptable. This should be accounted for, as OPEX and regulatory compliance can have differing behavioral priorities. The purpose of this dissertation is to provide theoretical and practical guidance for impacting shop floor behavior with pharmaceutical OPEX programs to facilitate balanced and high levels of operational performance. For this purpose, this research draws on literature on OPEX, Management Control (MC) and structuration theory to develop a research model in a first step. A mixed-method approach combining qualitative analysis and quantitative hierarchical linear regression analysis is then applied to empirically study the determinants of shop floor behavior in the context of pharmaceutical OPEX programs. The research findings suggest that the interplay between structural and behavioral determinants of shop floor behavior can lead to unintended consequences that are context dependent. They further suggest that this interplay is not comprehensively accounted for as part of pharmaceutical OPEX programs, since the underlying determinants are typically managed in isolation. Finally, the regression results underline the importance of taking unintended consequences that result from said interplay seriously, suggesting that MC has significant positive and negative moderation effects, which can increase respectively decrease the performance returns from OPEX programs.
Download or read book Knowledge Management in the Pharmaceutical Industry written by Elisabeth Goodman and published by Routledge. This book was released on 2016-04-22 with total page 204 pages. Available in PDF, EPUB and Kindle. Book excerpt: The Pharmaceutical Industry has been undergoing a major transformation since the heady days of 'big pharma' in the 1970s and 80s. Patent expiry, the rise of generics, and the decline of the blockbuster drug have all changed the landscape over the last 10-15 years. It's an environment where products can take 10 years or more to come to market, billions are spent on research and development, jobs are being shed in the western pharma homelands and regulators and the public are more demanding than ever. So what part is Knowledge Management playing and going to play in this vital international industry? Knowledge Management (KM) has many facets from providing comprehensive knowledge bases for workers, through the sharing of advice and problem solving, to providing an environment for innovation and change. This book, focusing on research and development, and manufacturing-based companies, explores how a range of techniques and approaches have been applied in the unique environment of the Pharmaceutical Industry, and examine how it can help the industry in the 21st century. Whilst the book is centered on the Pharmaceutical Industry, its objective will be to discuss and demonstrate how Knowledge Management can be applied in a variety of environments, and with a range of cultural issues. KM practitioners, and potential practitioners, both within and outside the Pharmaceutical Industry, will be able to gain valuable guidance and advice from both the examples of good practice and the lessons learned by the authors and contributors.
Download or read book Operational Excellence Across Manufacturing and Quality Control written by Marten Ritz and published by . This book was released on 2022 with total page 0 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Download or read book Value Creation in the Pharmaceutical Industry written by Alexander Schuhmacher and published by John Wiley & Sons. This book was released on 2016-04-11 with total page 511 pages. Available in PDF, EPUB and Kindle. Book excerpt: This practical guide for advanced students and decision-makers in the pharma and biotech industry presents key success factors in R&D along with value creators in pharmaceutical innovation. A team of editors and authors with extensive experience in academia and industry and at some of the most prestigious business schools in Europe discusses in detail the innovation process in pharma as well as common and new research and innovation strategies. In doing so, they cover collaboration and partnerships, open innovation, biopharmaceuticals, translational medicine, good manufacturing practice, regulatory affairs, and portfolio management. Each chapter covers controversial aspects of recent developments in the pharmaceutical industry, with the aim of stimulating productive debates on the most effective and efficient innovation processes. A must-have for young professionals and MBA students preparing to enter R&D in pharma or biotech as well as for students on a combined BA/biomedical and natural sciences program.
Download or read book Strategic Management of Global Manufacturing Networks written by Thomas Friedli and published by Springer. This book was released on 2014-07-08 with total page 278 pages. Available in PDF, EPUB and Kindle. Book excerpt: The preceding process of globalization and the continuously rising competitive pressure on manufacturing companies in more developed economies unveiled the limits of classical site-focused optimization approaches. The focus of network optimization shifts ever more towards an integrative view of manufacturing networks, striving for a harmonization of the strategy-, configuration- and coordination levels. This book presents such an integrative approach to the strategic management of manufacturing networks. Besides strategic network requirements, this book discusses the derivation of an optimal global footprint and the optimization of network coordination activities. Special attention is paid to the site roles concept, especially to the concept of 'lead factory'. A large number of up-to-date cases from the producing industry enrich the book and provide the reader with vivid examples for the application of the presented concepts. Hence, this book is a must-read for both practitioners and academic researchers.
Download or read book A Lifecycle Approach to Knowledge Excellence in the Biopharmaceutical Industry written by Nuala Calnan and published by CRC Press. This book was released on 2017-06-26 with total page 547 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book addresses the rapidly emerging field of Knowledge Management in the pharmaceutical, medical devices and medical diagnostics industries. In particular, it explores the role that Knowledge Management can play in ensuring the delivery of safe and effective products to patients. The book also provides good practice examples of how the effective use of an organisation’s knowledge assets can provide a path towards business excellence.
