Download or read book The Neuroscience of Traumatic Brain Injury written by Rajkumar Rajendram and published by Academic Press. This book was released on 2022-05-27 with total page 1206 pages. Available in PDF, EPUB and Kindle. Book excerpt: Diagnosis and Treatment of Traumatic Brain Injury will improve readers' understanding of the complexities of diagnosis and management of traumatic brain injuries. Featuring chapters on drug delivery, different treatments, and rehabilitation, this volume discusses in detail the impact early diagnosis and effective management has on the long-term prognosis of these injuries and the lives of those affected. This book will be relevant for neuroscientists, neurologists, clinicians, and anyone working to better understand these injuries. Traumatic brain injury has complex etiology and may arise as a consequence of physical abuse, violence, war, vehicle collisions, working in the construction industry, and sports. Cellular, Molecular, Physiological, and Behavioral Aspects of Traumatic Brain Injury will improve readers' understanding of the detailed processes arising from traumatic brain injury. Featuring chapters on neuroinflammation, metabolism, and psychology, this volume discusses the impact of these injuries on neurological and body systems to better understand underlying pathways. This book will be relevant for neuroscientists, neurologists, clinicians, and anyone working to better understand traumatic brain injury. Diagnosis and Treatment of Traumatic Brain Injury: - Covers both the diagnosis and treatment of traumatic brain cord injury - Contains chapter abstracts, key facts, dictionary, and summary points to aid in understanding - Features chapters on epidemiology and pain - Includes MRI usage, biomarkers, and stem cell and gene therapy for management of spinal cord injury - Discusses pain reduction, drug delivery, and rehabilitation Cellular, Molecular, Physiological, and Behavioral Aspects of Traumatic Brain Injury: - Summarizes the neuroscience of traumatic brain injury, including cellular and molecular biology - Contains chapter abstracts, key facts, dictionary, and summary points to aid in understanding - Features chapters on signaling and hormonal events - Includes plasticity and gene expression - Examines health and stress behaviors after traumatic brain injury

Download or read book Translational Research in Traumatic Brain Injury written by Daniel Laskowitz and published by CRC Press. This book was released on 2016-04-21 with total page 388 pages. Available in PDF, EPUB and Kindle. Book excerpt: Traumatic brain injury (TBI) remains a significant source of death and permanent disability, contributing to nearly one-third of all injury related deaths in the United States and exacting a profound personal and economic toll. Despite the increased resources that have recently been brought to bear to improve our understanding of TBI, the developme

Download or read book Diagnosis and Treatment of Traumatic Brain Injury written by Rajkumar Rajendram and published by Academic Press. This book was released on 2022-05-10 with total page 592 pages. Available in PDF, EPUB and Kindle. Book excerpt: Diagnosis and Treatment of Traumatic Brain Injury will improve readers' understanding of the complexities of diagnosis and management of traumatic brain injuries. Featuring chapters on drug delivery, different treatments, and rehabilitation, this volume discusses in detail the impact early diagnosis and effective management has on the long-term prognosis of these injuries and the lives of those affected. This book will be relevant for neuroscientists, neurologists, clinicians, and anyone working to better understand these injuries. - Covers both the diagnosis and treatment of traumatic brain cord injury - Contains chapter abstracts, key facts, dictionary, and summary points to aid in understanding - Features chapters on epidemiology and pain - Includes MRI usage, biomarkers, and stem cell and gene therapy for management of spinal cord injury - Discusses pain reduction, drug delivery, and rehabilitation

Download or read book Evaluation of the Disability Determination Process for Traumatic Brain Injury in Veterans written by National Academies of Sciences, Engineering, and Medicine and published by National Academies Press. This book was released on 2019-05-20 with total page 211 pages. Available in PDF, EPUB and Kindle. Book excerpt: The Veterans Benefits Administration (VBA) provides disability compensation to veterans with a service-connected injury, and to receive disability compensation from the Department of Veterans Affairs (VA), a veteran must submit a claim or have a claim submitted on his or her behalf. Evaluation of the Disability Determination Process for Traumatic Brain Injury in Veterans reviews the process by which the VA assesses impairments resulting from traumatic brain injury for purposes of awarding disability compensation. This report also provides recommendations for legislative or administrative action for improving the adjudication of veterans' claims seeking entitlement to compensation for all impairments arising from a traumatic brain injury.

Download or read book Brain Neurotrauma written by Firas H. Kobeissy and published by CRC Press. This book was released on 2015-02-25 with total page 718 pages. Available in PDF, EPUB and Kindle. Book excerpt: With the contribution from more than one hundred CNS neurotrauma experts, this book provides a comprehensive and up-to-date account on the latest developments in the area of neurotrauma including biomarker studies, experimental models, diagnostic methods, and neurotherapeutic intervention strategies in brain injury research. It discusses neurotrauma mechanisms, biomarker discovery, and neurocognitive and neurobehavioral deficits. Also included are medical interventions and recent neurotherapeutics used in the area of brain injury that have been translated to the area of rehabilitation research. In addition, a section is devoted to models of milder CNS injury, including sports injuries.

Download or read book Sports Related Concussions in Youth written by National Research Council and published by National Academies Press. This book was released on 2014-02-04 with total page 215 pages. Available in PDF, EPUB and Kindle. Book excerpt: In the past decade, few subjects at the intersection of medicine and sports have generated as much public interest as sports-related concussions - especially among youth. Despite growing awareness of sports-related concussions and campaigns to educate athletes, coaches, physicians, and parents of young athletes about concussion recognition and management, confusion and controversy persist in many areas. Currently, diagnosis is based primarily on the symptoms reported by the individual rather than on objective diagnostic markers, and there is little empirical evidence for the optimal degree and duration of physical rest needed to promote recovery or the best timing and approach for returning to full physical activity. Sports-Related Concussions in Youth: Improving the Science, Changing the Culture reviews the science of sports-related concussions in youth from elementary school through young adulthood, as well as in military personnel and their dependents. This report recommends actions that can be taken by a range of audiences - including research funding agencies, legislatures, state and school superintendents and athletic directors, military organizations, and equipment manufacturers, as well as youth who participate in sports and their parents - to improve what is known about concussions and to reduce their occurrence. Sports-Related Concussions in Youth finds that while some studies provide useful information, much remains unknown about the extent of concussions in youth; how to diagnose, manage, and prevent concussions; and the short- and long-term consequences of concussions as well as repetitive head impacts that do not result in concussion symptoms. The culture of sports negatively influences athletes' self-reporting of concussion symptoms and their adherence to return-to-play guidance. Athletes, their teammates, and, in some cases, coaches and parents may not fully appreciate the health threats posed by concussions. Similarly, military recruits are immersed in a culture that includes devotion to duty and service before self, and the critical nature of concussions may often go unheeded. According to Sports-Related Concussions in Youth, if the youth sports community can adopt the belief that concussions are serious injuries and emphasize care for players with concussions until they are fully recovered, then the culture in which these athletes perform and compete will become much safer. Improving understanding of the extent, causes, effects, and prevention of sports-related concussions is vitally important for the health and well-being of youth athletes. The findings and recommendations in this report set a direction for research to reach this goal.

Download or read book Neurosensory Disorders in Mild Traumatic Brain Injury written by Michael E. Hoffer and published by Academic Press. This book was released on 2018-11-24 with total page 453 pages. Available in PDF, EPUB and Kindle. Book excerpt: Mild traumatic Brain Injury (mTBI or Concussion) is an increasingly common public health issue in sports, military environments, and life in today's active world. Despite a great deal of study and public attention to this disorder, knowledge about optimal diagnostic, prognostic, and treatment information remains lacking. Neurosensory symptoms have been shown to be the most frequent complications of mTBI in both the acute and chronic setting. Neurosensory Disorders in Mild Traumatic Brain Injury brings together both the basic science work as well as the clinical work in mTBI into one volume to provide a comprehensive examination of the neurosensory issues associated with this disorder. Coverage includes chapters on defining mild Traumatic Brain Injury, neurosensory consequences, neurosensory disorders in clinical practice, and diagnosis and treatment for neurosensory disorders in mTBI. This book is written for clinicians, researchers, residents and students in neurology and neuroscience. - Provides a comprehensive examination of the neurosensory issues associated with mild Traumatic Brain Injury and concussion - Brings together both the basic science work and the clinical work in mTBI into a single volume - Helps clinicians understand the best diagnosis and treatment paths and puts current research into perspective for researchers

Download or read book Textbook of Traumatic Brain Injury Third Edition written by Jonathan M. Silver, M.D. and published by American Psychiatric Pub. This book was released on 2018-12-05 with total page 996 pages. Available in PDF, EPUB and Kindle. Book excerpt: Despite the increased public awareness of traumatic brain injury (TBI), the complexities of the neuropsychiatric, neuropsychological, neurological, and other physical consequences of TBI of all severities across the lifespan remain incompletely understood by patients, their families, healthcare providers, and the media. Keeping pace with advances in the diagnosis, treatment, and science of TBI, the Textbook of Traumatic Brain Injury, Third Edition, comprehensively fills this gap in knowledge. Nearly all 50 chapters feature new authors, all of them experts in their field. Chapters new to this edition include biomechanical forces, biomarkers, neurodegenerative dementias, suicide, endocrine disorders, chronic disease management, and social cognition. An entirely new section is devoted to the evaluation and treatment of mild TBI, including injuries in athletes, military service members and veterans, and children and adolescents. These chapters join newly updated sections on the assessment and treatment of the cognitive, emotional, behavioral, and other physical sequelae of TBI. The Textbook of Traumatic Brain Injury is a must-read for all of those working in any of the multitude of disciplines that contribute to the care and rehabilitation of persons with brain injury. This new volume is also a potentially useful reference for policymakers in both the public and private sectors.

Download or read book Handbook on the Neuropsychology of Traumatic Brain Injury written by Mark Sherer and published by Springer. This book was released on 2014-05-17 with total page 419 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book collects and synthesizes the latest thinking on the condition in its variety of cognitive and behavioral presentations, matched by a variety of clinical responses. Acknowledging the continuum of injury and the multi-stage nature of recovery, expert contributors review salient research data and offer clinical guidelines for the neuropsychologist working with TBI patients, detailing key areas of impairment, brief and comprehensive assessment methods and proven rehabilitation strategies. Taken together, these chapters provide a framework for best serving a wide range of TBI patients (including children, elders, and patients in multidisciplinary settings) and model treatment that is evidence-based and relevant. A sample of the topics featured in the Handbook: Bedside evaluations in TBI. Outcome assessment in TBI. Collaborating with family caregivers in the rehabilitation of persons with TBI. Behavioral assessment of acute neurobehavioral syndromes to inform treatment. Pediatric TBI: assessment, outcomes, intervention. Special issues with mild TBI in veterans and active duty service members. Expanding professional knowledge on a topic that continues to grow in importance, the Handbook on the Neuropsychology of Traumatic Brain Injury is a premier resource, not only for neuropsychologists but also for other professionals in cognitive care, and trainees entering the field.

Download or read book Working with Traumatic Brain Injury in Schools written by Paul B. Jantz and published by Routledge. This book was released on 2014-01-10 with total page 250 pages. Available in PDF, EPUB and Kindle. Book excerpt: Every day, children and adolescents worldwide return to the educational setting having sustained a traumatic brain injury (TBI). The possible negative consequences of TBI range from mild to severe and include neurological, cognitive, emotional, social, and behavioral difficulties. Within the school setting, the negative effects of TBI tend to persist or worsen over time, often resulting in academic and social difficulties that require formal and informal educational assistance and support. School psychologists and other educational professionals are well-positioned to help ensure students with TBI receive this assistance and support. Working with Traumatic Brain Injury in Schools is a comprehensive practitioner-oriented guide to effective school-based services for students who have experienced a TBI. It is primarily written for school-based professionals who have limited or no neurological or neuropsychological training; however, it contains educational information that is useful to professionals with extensive knowledge in neurology and/or neuropsychology. This book is also written for parents and guardians of students with TBI because of their integral role in the transition, school-based assessment, and school-based intervention processes. Chapter topics include: basic brain anatomy and physiology; head injury and severity level classifications; biomechanics of injury; injury recovery and rehabilitation; neurological, cognitive, emotional, behavioral, social, and academic consequences; understanding community-based assessment findings; a framework for school-based assessment (TBI-SNNAP); school-based psychoeducational report writing, and school-based interventions; monitoring pharmacological interventions; and prevention. An accompanying website includes handouts, sample reports, and training templates to assist professionals in recognizing and responding to students with TBI.

Download or read book Tau oligomers written by Jesus Avila and published by Frontiers E-books. This book was released on 2014-08-18 with total page 114 pages. Available in PDF, EPUB and Kindle. Book excerpt: Neurofibrillary tangles (NFTs) composed of intracellular aggregates of tau protein are a key neuropathological feature of Alzheimer’s Disease (AD) and other neurodegenerative diseases, collectively termed tauopathies. The abundance of NFTs has been reported to correlate positively with the severity of cognitive impairment in AD. However, accumulating evidences derived from studies of experimental models have identified that NFTs themselves may not be neurotoxic. Now, many of tau researchers are seeking a “toxic” form of tau protein. Moreover, it was suggested that a “toxic” tau was capable to seed aggregation of native tau protein and to propagate in a prion-like manner. However, the exact neurotoxic tau species remain unclear. Because mature tangles seem to be non-toxic component, “tau oligomers” as the candidate of “toxic” tau have been investigated for more than one decade. In this topic, we will discuss our consensus of “tau oligomers” because the term of “tau oligomers” [e.g. dimer (disulfide bond-dependent or independent), multimer (more than dimer), granular (definition by EM or AFM) and maybe small filamentous aggregates] has been used by each researchers definition. From a biochemical point of view, tau protein has several unique characteristics such as natively unfolded conformation, thermo-stability, acid-stability, and capability of post-translational modifications. Although tau protein research has been continued for a long time, we are still missing the mechanisms of NFT formation. It is unclear how the conversion is occurred from natively unfolded protein to abnormally mis-folded protein. It remains unknown how tau protein can be formed filaments [e.g. paired helical filament (PHF), straight filament and twisted filament] in cells albeit in vitro studies confirmed tau self-assembly by several inducing factors. Researchers are still debating whether tau oligomerization is primary event rather than tau phosphorylation in the tau pathogenesis. Inhibition of either tau phosphorylation or aggregation has been investigated for the prevention of tauopathies, however, it will make an irrelevant result if we don’t know an exact target of neurotoxicity. It is a time to have a consensus of definition, terminology and methodology for the identification of “tau oligomers”.

Download or read book Handbook of Traumatic Brain Injury and Neurodegeneration written by R.J. Castellani and published by IOS Press. This book was released on 2020-04-24 with total page 506 pages. Available in PDF, EPUB and Kindle. Book excerpt: Holbourne’s theory that rotational head movement and shear strains were limiting factors in producing acute parenchymal brain damage was a watershed moment in understanding traumatic brain injury (TBI). Long term effects, and in particular neurodegenerative proteinopathy subsequent to TBI, remain theoretical, notwithstanding the poorly understood ‘punch drunk’ syndrome of the early and mid-20th century, and the 21st century concept of chronic traumatic encephalopathy. This book, the Handbook of Traumatic Brain Injury and Neurodegeneration, has as its theme the marriage between neurodegenerative disease and neurotrauma through TBI surrogates such as sport, military service, and experimental models, and the legitimacy of that marriage. In the 32 contributions included here, this handbook not only explores the deleterious effects of genuine TBI, but also, and more importantly, the relationship between TBI and neurodegeneration. Controversy notwithstanding, there is much to be learned about the biological effects of TBI, substrates for long-term sequelae, the relationship between TBI and diverse neuropsychiatric disorders, and targets for therapy. The overall message to the neuroscience community from these papers may be a cautionary tale. The null hypothesis, that there is no causal relationship between TBI and progressive neurodegenerative disease, appears to be very much in play, and the book will be of interest to all those working in the field.

Download or read book Traumatic Brain and Spinal Cord Injury written by Cristina Morganti-Kossmann and published by Cambridge University Press. This book was released on 2012-07-19 with total page 361 pages. Available in PDF, EPUB and Kindle. Book excerpt: Presents the most up-to-date clinical and experimental research in neurotrauma in an illustrated, accessible, comprehensive volume.

Download or read book Management of Adults with Traumatic Brain Injury written by David Brian Arciniegas and published by American Psychiatric Pub. This book was released on 2013 with total page 598 pages. Available in PDF, EPUB and Kindle. Book excerpt: Management of Adults with Traumatic Brain Injury is an up-to-the-minute, comprehensive, and useful text designed to support busy physicians, nurses, and mental health professionals working with persons with traumatic brain injury (TBI) and their families. Understanding and improving outcomes after TBI requires consideration of the effects of biomechanical forces on the brain and the interactions between the injury, the person experiencing it, and the psychosocial context in which TBI and its consequences occur. A multidisciplinary approach to the management of persons with TBI therefore is essential. Accordingly, this book presents and synthesizes the work of internationally recognized brain injury clinicians, scientists, and educators who were selected by a team of editors with backgrounds in psychiatry, neurology, psychology, and physiatry. This broad range of perspectives enhances understanding and provides nuanced yet practical information on the neuropsychiatric management of persons with TBI. Evidence-informed, concise, and clinically rich, Management of Adults with Traumatic Brain Injury will be of enormous value to health care providers grappling with the neurological and mental health consequences of this widespread public health problem.

Download or read book PTSD and Mild Traumatic Brain Injury written by Jennifer J. Vasterling and published by Guilford Press. This book was released on 2012-02-01 with total page 324 pages. Available in PDF, EPUB and Kindle. Book excerpt: Posttraumatic stress disorder (PTSD) and mild traumatic brain injury (mTBI) can each cause significant functional impairment--and these "invisible injuries" frequently co-occur. Events that lead to traumatic brain injury are often also psychologically traumatic. This authoritative volume brings together leading experts in PTSD and mTBI to explore the nature, consequences, and management of these interacting conditions. Presenting cutting-edge research and clinical practices, the book meets a growing need among mental health practitioners in both civilian and military contexts. The volume focuses on the complexities of caring for patients with comorbid PTSD and mTBI, whether caused by war-zone experiences, motor vehicle accidents, domestic violence or other interpersonal assaults, or sports concussions. Contributors examine the biological and psychosocial mechanisms underlying both disorders as well as potential ways they may affect each other. Commonly associated problems that may further complicate recovery--chronic pain and substance abuse--are also discussed in detail. Reviewing empirically based best practices in assessment and treatment, chapters offer recommendations for tailoring interventions to different patients' needs. Important topics include how to deal with dilemmas in evaluation and what treatment strategies work best for addressing overlapping symptoms. The book also considers ways to improve the structure and cost-effectiveness of providing care in this challenging area. Throughout, scientific controversies and unanswered questions are highlighted and promising directions for future research identified. Synthesizing knowledge from multiple disciplines, this is an essential reference for mental health practitioners and trauma specialists--including neuropsychologists, clinical psychologists, psychiatrists, and social workers--as well as graduate students and trainees.

Download or read book The Traumatized Brain written by Vani Rao and published by JHU Press. This book was released on 2015-11-15 with total page 219 pages. Available in PDF, EPUB and Kindle. Book excerpt: Useful information and real hope for patients and families whose lives have been altered by traumatic brain injury. A traumatic brain injury is a life-changing event, affecting an individual’s lifestyle, ability to work, relationships—even personality. Whatever caused it—car crash, work accident, sports injury, domestic violence, combat—a severe blow to the head results in acute and, often, lasting symptoms. People with brain injury benefit from understanding, patience, and assistance in recovering their bearings and functioning to their full abilities. In The Traumatized Brain, neuropsychiatrists Drs. Vani Rao and Sandeep Vaishnavi—experts in helping people heal after head trauma—explain how traumatic brain injury, whether mild, moderate, or severe, affects the brain. They advise readers on how emotional symptoms such as depression, anxiety, mania, and apathy can be treated; how behavioral symptoms such as psychosis, aggression, impulsivity, and sleep disturbances can be addressed; and how cognitive functions like attention, memory, executive functioning, and language can be improved. They also discuss headaches, seizures, vision problems, and other neurological symptoms of traumatic brain injury. By stressing that symptoms are real and are directly related to the trauma, Rao and Vaishnavi hope to restore dignity to people with traumatic brain injury and encourage them to ask for help. Each chapter incorporates case studies and suggestions for appropriate medications, counseling, and other treatments and ends with targeted tips for coping. The book also includes a useful glossary, a list of resources, and suggestions for further reading.

Download or read book Head Injury written by Peter C. Whitfield and published by Cambridge University Press. This book was released on 2009-04-09 with total page 327 pages. Available in PDF, EPUB and Kindle. Book excerpt: A pragmatic, and multi-professional approach to the management of head injured patients. Covers epidemiology, experimental models, pathology, clinical examination, neuroimaging, trauma scoring, patient management including emergency department care, transfer of the patient, intensive care and surgical aspects, rehabilitation, paediatric head injury and finally, medico-legal issues.