Download or read book The Neurobiology of the Gilles De La Tourette Syndrome and Chronic Tics Part B written by and published by Academic Press. This book was released on 2022-09-03 with total page 402 pages. Available in PDF, EPUB and Kindle. Book excerpt: The Neurobiology of the Gilles de la Tourette Syndrome and Chronic Tics, Part B, Volume Four reviews historical background, current nosology and guidelines. In addition, it includes an overview of pathophysiology, ranging from its genetic basis and changes in neurochemistry and electrophysiology to widespread neural circuits. Specific chapters cover The genetic basis of Gilles de la Tourette Syndrome, Genome-wide association study of Tourette Syndrome, De Novo mutations in Tourette Syndrome, Animal models for Tourette Syndrome, The neural-immune crosstalk in Tourette syndrome: from immunobiology to epistemology, Functional connectivity in the Gilles de la Tourette Syndrome, and much more. Includes examines of Gilles de la Tourette Syndrome at behavioral, cognitive, clinical, electrophysiological, molecular and genetic levels Provides a comprehensive overview of the neurobiological aspects of Gilles de la Tourette Syndrome Edited and authored by top researchers and clinicians treating Gilles de la Tourette Syndrome
Download or read book The Neurobiology of the Gilles De La Tourette Syndrome and Chronic Tics Part A written by and published by Academic Press. This book was released on 2022-07-06 with total page 464 pages. Available in PDF, EPUB and Kindle. Book excerpt: The Neurobiology of the Gilles de la Tourette Syndrome and Chronic Tics, Volume Three reviews historical background and current nosology and guidelines. In addition, it includes an overview of pathophysiology, ranging from its genetic basis and changes in neurochemistry and electrophysiology to widespread neural circuits. Specific chapters cover Tourette syndrome from phenomenology and natural history to neurobiology, Update and Recent progress in the Neurobiology of Tourette Syndrome, Current guidelines and nosology of Tourette syndrome, Neuroimaging applications in Tourette's Syndrome, Clinical and neurodevelopmental brain imaging of Tourette syndrome, Altered Structural Connectivity in Gilles de la Tourette Syndrome, and much more. The last 20?years have seen an exponential growing body of research dedicated to Gilles de la Tourette Syndrome in the understanding of the syndrome’s complex genetics and underlying neurobiology. This unprecedented surge in basic and clinical research has resulted in over 3,000 scientific publications. Examines Gilles de la Tourette Syndrome at behavioral, cognitive, clinical, electrophysiological, molecular and genetic levels Provides a comprehensive overview of the neurobiological aspects of Gilles de la Tourette Syndrome Edited and authored by top researchers and clinicians treating the Gilles de la Tourette Syndrome
Download or read book The Neurobiology of the Gilles De La Tourette Syndrome and Chronic Tics Part A written by and published by Academic Press. This book was released on 2022-07-25 with total page 0 pages. Available in PDF, EPUB and Kindle. Book excerpt: The Neurobiology of the Gilles de la Tourette Syndrome and Chronic Tics, Volume Three reviews historical background and current nosology and guidelines. In addition, it includes an overview of pathophysiology, ranging from its genetic basis and changes in neurochemistry and electrophysiology to widespread neural circuits. Specific chapters cover Tourette syndrome from phenomenology and natural history to neurobiology, Update and Recent progress in the Neurobiology of Tourette Syndrome, Current guidelines and nosology of Tourette syndrome, Neuroimaging applications in Tourette's Syndrome, Clinical and neurodevelopmental brain imaging of Tourette syndrome, Altered Structural Connectivity in Gilles de la Tourette Syndrome, and much more. The last 20?years have seen an exponential growing body of research dedicated to Gilles de la Tourette Syndrome in the understanding of the syndrome's complex genetics and underlying neurobiology. This unprecedented surge in basic and clinical research has resulted in over 3,000 scientific publications.
Download or read book The Neurobiology and Genetics of Gilles de la Tourette Syndrome New Avenues Through Large Scale Collaborative Projects written by Peristera Paschou and published by Frontiers Media SA. This book was released on 2018-03-13 with total page 324 pages. Available in PDF, EPUB and Kindle. Book excerpt: Gilles de la Tourette Syndrome (TS) is a common, albeit severely under-diagnosed, neuropsychiatric disorder that is caused by a complex genetic basis, interacting with environmental factors. High comorbidity rates with other neurodevelopmental disorders such as attention deficit/hyperactivity disorder and obsessive compulsive disorder raise the intriguing hypothesis of a shared etiological background. Abnormalities of corticostriatal-thalamic-cortical circuits (CSTC) and dysfunction of both dopamine and serotonin neurotransmitter systems are assumed to be associated with TS. Recently, multiple lines of evidence also point towards an important role of additional neurotransmitters such as histamine and glutamate. For a very long time, efforts to elucidate the etiology and pathophysiology of TS have been fragmented and hampered by low statistical power. Finally, after more than two decades of active research aiming to identify the etiology and pathophysiology of TS, we are on the verge of a new era, promising exciting and rapid discoveries in the field. Investigators from around the world, representing multiple disciplines and scientific approaches, are joining their efforts in large-scale initiatives supported both by European Union and US National funding agencies, such as the European-funded EMTICS, TACTICS, and TSGeneSEE consortia, the Marie Curie Initial Training Network TS-EUROTRAIN and the European Society for the Study of TS joining forces with the NIH-funded TSAICG, GGRI, and Tic Genetics consortia. Importantly, all these initiatives are supported by TS patient support and advocacy groups. Multiple resources are being consolidated and coming together to serve the study of TS, including large well-characterized patient cohorts, and specialized epidemiological databases, such as the unique resource of the Netherlands Twin Register. This research topic showcases current large-scale collaborative efforts aiming to elucidate the genetic and neurobiological background of TS, through diverse approaches; from genomewide association studies aiming to identify common variants associated to the disorder to neuroimaging studies and animal models. Furthermore, current approaches on the clinical assessment and management of the disorder are presented. Propelled by the gradual availability of large scale TS cohorts, novel methodologies, and importantly, sheer enthusiasm by multiple researchers working together across different countries, the new era of the neurobiology of TS holds the promise to identify novel targets for improved therapies.
Download or read book Handbook of Tourette s Syndrome and Related Tic and Behavioral Disorders written by Roger Kurlan and published by CRC Press. This book was released on 2004-10-27 with total page 560 pages. Available in PDF, EPUB and Kindle. Book excerpt: Relating breakthroughs in phenomenology and neurobiology and current strategies for diagnosis, assessment, and clinical care, this long-anticipated Second Edition provides expanded descriptions of clinical features, further evidence linking heritability to etiology, and revised epidemiological estimates as observed in the most recent research on To
Download or read book Tourette Syndrome written by Davide Martino and published by Oxford University Press. This book was released on 2022 with total page 577 pages. Available in PDF, EPUB and Kindle. Book excerpt: Tourette syndrome (TS) has become increasingly recognised within society and has gained scientific interest worldwide. Knowledge of its clinical presentation, mechanisms of disease, and available treatment approaches has increased remarkably over the last two decades. Likewise, the way clinicians, teachers, social care workers, and families face the problems manifested by patients with TS is rapidly evolving. Tourette Syndrome, edited by Davide Martino and James F. Leckman, offers a unique opportunity to capture this knowledge advance through a comprehensive and up-to-date overview. Tourette Syndrome covers all the main aspects related to TS, analyzing its complex clinical presentation, the novel viewpoints of causes and mechanisms, state-of-the-art assessment techniques, and the diversity of treatment options. Multidisciplinarity is the main asset of this volume, which represents a source of consultation for a wide audience of professionals, integrated with video tutorials related to particularly complex areas of patient management. Medical and PhD students, as well as post-doctoral scientists, will be able to use the volume as a valuable learning source.
Download or read book The Neurobiology and Genetics of Gilles de la Tourette Syndrome New Avenues Through Large Scale Collaborative Projects written by and published by . This book was released on 2018 with total page 0 pages. Available in PDF, EPUB and Kindle. Book excerpt: Gilles de la Tourette Syndrome (TS) is a common, albeit severely under-diagnosed, neuropsychiatric disorder that is caused by a complex genetic basis, interacting with environmental factors. High comorbidity rates with other neurodevelopmental disorders such as attention deficit/hyperactivity disorder and obsessive compulsive disorder raise the intriguing hypothesis of a shared etiological background. Abnormalities of corticostriatal-thalamic-cortical circuits (CSTC) and dysfunction of both dopamine and serotonin neurotransmitter systems are assumed to be associated with TS. Recently, multiple lines of evidence also point towards an important role of additional neurotransmitters such as histamine and glutamate. For a very long time, efforts to elucidate the etiology and pathophysiology of TS have been fragmented and hampered by low statistical power. Finally, after more than two decades of active research aiming to identify the etiology and pathophysiology of TS, we are on the verge of a new era, promising exciting and rapid discoveries in the field. Investigators from around the world, representing multiple disciplines and scientific approaches, are joining their efforts in large-scale initiatives supported both by European Union and US National funding agencies, such as the European-funded EMTICS, TACTICS, and TSGeneSEE consortia, the Marie Curie Initial Training Network TS-EUROTRAIN and the European Society for the Study of TS joining forces with the NIH-funded TSAICG, GGRI, and Tic Genetics consortia. Importantly, all these initiatives are supported by TS patient support and advocacy groups. Multiple resources are being consolidated and coming together to serve the study of TS, including large well-characterized patient cohorts, and specialized epidemiological databases, such as the unique resource of the Netherlands Twin Register. This research topic showcases current large-scale collaborative efforts aiming to elucidate the genetic and neurobiological background of TS, through diverse approaches; from genomewide association studies aiming to identify common variants associated to the disorder to neuroimaging studies and animal models. Furthermore, current approaches on the clinical assessment and management of the disorder are presented. Propelled by the gradual availability of large scale TS cohorts, novel methodologies, and importantly, sheer enthusiasm by multiple researchers working together across different countries, the new era of the neurobiology of TS holds the promise to identify novel targets for improved therapies.
Download or read book Advances in the Neurochemistry and Neuropharmacology of Tourette Syndrome written by and published by Academic Press. This book was released on 2013-11-27 with total page 572 pages. Available in PDF, EPUB and Kindle. Book excerpt: This volume of International Review of Neurobiology brings together cutting-edge research on advances in the neurochemistry and neuropharmacology of Tourette syndrome. It reviews current knowledge and understanding, provides a starting point for researchers and practitioners entering the field, and includes important topics regards tics, neurotransmitters, pharmacology and emerging treatments. - This volume of brings together research on tourettes synrdrome. It reviews current knowledge and understanding on the neurochemistry and neuropharmacology of tourettes syndrome
Download or read book Tourette Syndrome written by John T. Walkup and published by Lippincott Williams & Wilkins. This book was released on 2006 with total page 296 pages. Available in PDF, EPUB and Kindle. Book excerpt: This volume provides a summary review of all recently published and ongoing research initiatives related to Tourette Syndrome. The latest research is presented in a clinical context, and controversial issues are fully discussed using an evidence-based approach. These issues include the prevalence of TS, the nature of the TS phenotype, the role of autoimmunity in the development of TS, the role of comorbidity in functional outcomes of TS patients, and approaches to identifying the TS gene/genes. Chapters describe recent advances in neuroimaging, genetics, and treatment. The book includes extensive discussions of co-morbid disorders: obsessive-compulsive disorder, attention deficit hyperactivity disorder, mood disorders, and tics.
Download or read book Tourette Syndrome written by Thomas Newell Chase and published by Lippincott Williams & Wilkins. This book was released on 1992 with total page 410 pages. Available in PDF, EPUB and Kindle. Book excerpt: This volume presents an encyclopedic account of the past decade's achievements in the study and treatment of Tourette Syndrome (TS) and associated behavioral and psychiatric disorders. More than 90 of the foremost authorities from all relevant basic science, clinical, and behavioral science disciplines highlight the major recent developments worldwide - from groundbreaking genetic and neurochemical research and studies using state-of-the-art neuroimaging technologies, to new concepts on the clinical spectrum and natural history of TS, increasing recognition of comorbid conditions, and improved strategies for pharmacotherapy and psychosocial management. The contributors assess the practical utility of current diagnostic criteria for TS and present extensive data on its natural history, its range of clinical manifestations, and its associated disorders. The findings indicate that the severity of TS varies widely among patients, that tics tend to diminish during adolescence and adulthood, and that comorbid conditions - such as obsessive-compulsive disorder and attention deficit hyperactivity disorder - are often the chief source of impairment. Much evidence suggests that these disturbances and the tics are manifestations of the same underlying diathesis. Noted investigators document significant findings on the mode of inheritance for TS, define the key methodological issues in genetic linkage studies, and describe molecular approaches to the search for the genetic locus for the syndrome. The book also includes new data implicating specific monoamine neurotransmitters and endogenous opioid peptides in the pathogenesis of TS. Other contributors present neuroimaging studies using MRI, PET, and SPECT to delineate brain mechanisms involved in TS. The book offers definitive guidelines on pharmacotherapy for tics and, particularly, for associated obsessive-compulsive disorder (OCD) and attention deficit hyperactivity disorder (ADHD). Of special note are the discussions on treatment of OCD with serotonin reuptake inhibitors and on use of clonidine and stimulants for ADHD with comorbid tics. Additional chapters explore the potential of novel drugs and of nutritional interventions such as megavitamin therapy. Full consideration is also given to the role of behavioral and psychosocial therapies and the educational management of children with TS. This volume is an indispensable resource for all clinicians and investigators involved in the treatment or study of neuropsychiatric disorders. It exemplifies the creative application of the full range of current neuroscience and behavioral methodologies to a complex and important syndrome.
Download or read book Tourette s Syndrome Tics Obsessions Compulsions written by James F. Leckman and published by John Wiley & Sons. This book was released on 1998-11-09 with total page 606 pages. Available in PDF, EPUB and Kindle. Book excerpt: Früher wurde das Tourette-Syndrom (TS) als seltene Störung betrachtet; mittlerweile jedoch wurde erkannt, daß TS häufig in der Kindheit beginnt. Man weiß jetzt auch, daß die Anfälligkeit für TS über Generationen hinweg vererbt wird. Diagnose, Genetik, Phänomenologie, Geschichte und Behandlung von TS werden hier dargestellt, ausgehend von einem einmaligen Ansatz, der Beziehungen zwischen der Störung und dem normalen Entwicklungsweg herstellt. (8/98)
Download or read book Georges Gilles de la Tourette written by Olivier Walusinski and published by . This book was released on 2019 with total page 513 pages. Available in PDF, EPUB and Kindle. Book excerpt: This biography is the first comprehensive volume to delve into the life, scholarship, writing, and hobbies of the famed doctor, for whom Tourette's Syndrome is named. In Part One, we learn Georges' family history, follow his schooling and mentorship under Charcot, travel to the World's Fair of 1900, and evade an attempted assassination, all before succumbing to death by syphilis. Part Two provides an in-depth analysis of his neurological and psychiatric works, notably the eponymous neurological disorder that will forever remain "Tourette's Syndrome." Part Three looks at the lighter side of Georges, inspecting his favorite past-times as poet, historian, and art critic. Part Four brings an extensive bibliography of Georges' complete body of work.
Download or read book Pharmacological Treatment of Tics written by Andrea Cavanna and published by Cambridge University Press. This book was released on 2020-07-30 with total page 201 pages. Available in PDF, EPUB and Kindle. Book excerpt: A practical handbook on the pharmacological treatment of tics in patients with Tourette syndrome and other tic disorders.
Download or read book Autonomic Dysfunction in Parkinson s Disease written by Cristian Falup-Pecurariu and published by Academic Press. This book was released on 2021-09-28 with total page 316 pages. Available in PDF, EPUB and Kindle. Book excerpt: Autonomic dysfunction is one of the most prevalent non-motor symptoms that occurs in Parkinson's disease. Autonomic Dysfunction in Parkinson's Disease provides up to date information on this important topic, which affects quality of life of these patients. This include a large number of domains: orthostatic hypotension, excessive sweating, dry eyes, constipation, weight loss, increased sensitivity to heat and cold, sexual dysfunction. - Provides comprehensive reviews on different topics of autonomic dysfunction in Parkinson's disease - Each chapter covers a specific autonomic symptom: classification, assessment, treatment - Presents the newest information on each autonomic symptom in Parkinson's disease
Download or read book Tourette Syndrome written by Mary Robertson and published by OUP Oxford. This book was released on 2008-10-16 with total page 184 pages. Available in PDF, EPUB and Kindle. Book excerpt: Tourette's Syndrome (TS) is an inherited neuropsychiatric disorder affecting up to 1% of the population. It is characterised by motor and vocal tics, and upsetting anti-social behaviour such as involuntary swearing and obscene gestures. This second edition of Tourette Syndrome: The Facts explains the causes of the syndrome, how it is diagnosed, and how to cope if you or a relative has been recently diagnosed. It provides information on the treatment and therapies that are available, and advice and on how individuals can manage their symptoms. It clearly explains the different presentations that can affected individuals, covering a spectrum from very mild to more uncommon severe forms of TS, and also discusses disorders that can be mistaken for TS. This edition contains a new chapters focussing on 'Education, employment and empowerment', and famous and successful people who achieved their goals despite their diagnosis. Essential reading for Tourette's sufferers, their relatives and friends, Tourette's Syndrome: The Facts will also be of use to clinicians, GPs, schoolteachers, and anyone seeking an accessible introduction to the disorder.
Download or read book I Heard There Was A Secret Chord written by Daniel J. Levitin and published by Penguin. This book was released on 2024-08-27 with total page 417 pages. Available in PDF, EPUB and Kindle. Book excerpt: Neuroscientist and New York Times bestselling author of This Is Your Brain on Music Daniel J. Levitin reveals how the deep connections between music and the human brain can be harnessed for healing. Music is perhaps one of humanity’s oldest medicines as well as its most universal: from China to the Ottoman Empire, Europe to Africa and pre-colonial South America, cultures have developed rich traditions for using sound and rhythm to ease suffering, spur healing, and calm the mind. Despite this history, musical therapy has long been considered the remit of ancient practice and alternative medicine, if not outright quackery and pseudoscience. In the last decade, however, an overwhelming body of scientific evidence has emerged that persuasively argues music can offer profoundly effective treatment for a whole host of ailments, from Alzheimer’s to PTSD, depression, pain, and cognitive injury. It is, in short, one of the most potent and remarkably promising new therapies available today. A work of dazzling ideas, cutting-edge research, and joyful celebration of the human mind, I Heard There Was a Secret Chord explores the critical role music has played in human evolution, illuminating how the story of the human brain is inseparable from the creative enterprise of music that has bound cultures together throughout history. Music insinuates itself into our earliest memories; it is intimately connected to our emotional regulation and cognition; its shared rhythms and sounds are essential to our social behaviors. As neuroscientist Daniel J. Levitin demonstrates in this mind-expanding follow-up to This Is Your Brain on Music—which revolutionized our understanding of the neuroscience of song—medical researchers are now finding that these same deep connections can be harnessed to create profound benefits for those both young and old.
Download or read book Handbook of Tourette s Syndrome and Related Tic and Behavioral Disorders Second Edition written by Roger Kurlan and published by CRC Press. This book was released on 2004-10-27 with total page 560 pages. Available in PDF, EPUB and Kindle. Book excerpt: Relating breakthroughs in phenomenology and neurobiology and current strategies for diagnosis, assessment, and clinical care, this long-anticipated Second Edition provides expanded descriptions of clinical features, further evidence linking heritability to etiology, and revised epidemiological estimates as observed in the most recent research on Tourette's syndrome (TS) and associated disorders. The latest information about the controversial poststreptococcal hypothesis is also presented and discussed.
