Download or read book The FitzHugh Nagumo Model written by C. Rocsoreanu and published by Springer Science & Business Media. This book was released on 2012-12-06 with total page 245 pages. Available in PDF, EPUB and Kindle. Book excerpt: The present monograph analyses the FitzHugh-Nagumo (F-N) model Le. , the Cauchy problem for some generalized Van der Pol equation depending on three real parameters a, band c. This model, given in (1. 1. 17), governs the initiation of the cardiac impulse. The presence of the three parameters leads to a large variety of dy namics, each of them responsible for a specific functioning of the heart. For physiologists it is highly desirable to have aglobai view of all possible qualitatively distinct responses of the F-N model for all values of the pa rameters. This reduces to the knowledge of the global bifurcation diagram. So far, only a few partial results appeared and they were spread through out the literature. Our work provides a more or less complete theoretical and numerical investigation of the complex phase dynamics and bifurca tions associated with the F-N dynamical system. This study includes the static and dynamic bifurcations generated by the variation of a, band c and the corresponding oscillations, of special interest for applications. It enables one to predict all possible types of initiations of heart beats and the mechanism of transformation of some types of oscillations into others by following the dynamics along transient phase space trajectories. Of course, all these results hold for the F-N model. The global phase space picture enables one to determine the domain of validity of this model.
Download or read book The FitzHugh Nagumo Model written by C. Rocsoreanu and published by Springer. This book was released on 2014-10-09 with total page 238 pages. Available in PDF, EPUB and Kindle. Book excerpt: The present monograph analyses the FitzHugh-Nagumo (F-N) model Le. , the Cauchy problem for some generalized Van der Pol equation depending on three real parameters a, band c. This model, given in (1. 1. 17), governs the initiation of the cardiac impulse. The presence of the three parameters leads to a large variety of dy namics, each of them responsible for a specific functioning of the heart. For physiologists it is highly desirable to have aglobai view of all possible qualitatively distinct responses of the F-N model for all values of the pa rameters. This reduces to the knowledge of the global bifurcation diagram. So far, only a few partial results appeared and they were spread through out the literature. Our work provides a more or less complete theoretical and numerical investigation of the complex phase dynamics and bifurca tions associated with the F-N dynamical system. This study includes the static and dynamic bifurcations generated by the variation of a, band c and the corresponding oscillations, of special interest for applications. It enables one to predict all possible types of initiations of heart beats and the mechanism of transformation of some types of oscillations into others by following the dynamics along transient phase space trajectories. Of course, all these results hold for the F-N model. The global phase space picture enables one to determine the domain of validity of this model.
Download or read book The FitzHugh Nagumo Model written by C. Rocsoreanu and published by Taylor & Francis US. This book was released on 2000-08-31 with total page 258 pages. Available in PDF, EPUB and Kindle. Book excerpt: This application-oriented monograph presents a comprehensive theoretical and numerical investigation of all types of oscillators and bifurcations (such as Hopf, Bogdanov-Takens, Bautin, and homoclinic) generated by the FitzHugh-Nagumo model. The wide diversity of the oscillators as used in electrophysiology, biology, and engineering is emphasised. Various asymptotic behaviours are revealed. The dramatic changes in oscillations connected with the emergence or disappearance of concave limit cycles are investigated. Codimension of bifurcations is minutely analysed. New types of codimension one and two bifurcations of planar systems were found. A detailed global bifurcation diagram concludes the work. Audience: This volume will be of interest to researchers and graduate students whose work involves the mathematics of biology, ordinary differential equations, approximations and expansions, cardiac electrophysiology, biological transport, and cell membranes.
Download or read book Encyclopedia of Computational Neuroscience written by Dieter Jaeger and published by . This book was released on with total page pages. Available in PDF, EPUB and Kindle. Book excerpt:
Download or read book Dynamical Systems in Neuroscience written by Eugene M. Izhikevich and published by MIT Press. This book was released on 2010-01-22 with total page 459 pages. Available in PDF, EPUB and Kindle. Book excerpt: Explains the relationship of electrophysiology, nonlinear dynamics, and the computational properties of neurons, with each concept presented in terms of both neuroscience and mathematics and illustrated using geometrical intuition. In order to model neuronal behavior or to interpret the results of modeling studies, neuroscientists must call upon methods of nonlinear dynamics. This book offers an introduction to nonlinear dynamical systems theory for researchers and graduate students in neuroscience. It also provides an overview of neuroscience for mathematicians who want to learn the basic facts of electrophysiology. Dynamical Systems in Neuroscience presents a systematic study of the relationship of electrophysiology, nonlinear dynamics, and computational properties of neurons. It emphasizes that information processing in the brain depends not only on the electrophysiological properties of neurons but also on their dynamical properties. The book introduces dynamical systems, starting with one- and two-dimensional Hodgkin-Huxley-type models and continuing to a description of bursting systems. Each chapter proceeds from the simple to the complex, and provides sample problems at the end. The book explains all necessary mathematical concepts using geometrical intuition; it includes many figures and few equations, making it especially suitable for non-mathematicians. Each concept is presented in terms of both neuroscience and mathematics, providing a link between the two disciplines. Nonlinear dynamical systems theory is at the core of computational neuroscience research, but it is not a standard part of the graduate neuroscience curriculum—or taught by math or physics department in a way that is suitable for students of biology. This book offers neuroscience students and researchers a comprehensive account of concepts and methods increasingly used in computational neuroscience. An additional chapter on synchronization, with more advanced material, can be found at the author's website, www.izhikevich.com.
Download or read book Nonlinear Dynamics The Richard Rand 50th Anniversary Volume written by Ardeshir Guran and published by World Scientific. This book was released on 1997-12-16 with total page 248 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book is a collection of papers on the subject of nonlinear dynamics and its applications written by experts in this field. It offers the reader a sampling of exciting research areas in this fast-growing field. The topics covered include chaos, tools to analyze motions, fractal boundaries, dynamics of the Fitzhugh-Nagumo equation, structural control, separation of contaminations from signal of interest, parametric excitation, stochastic bifurcation, mode localization in repetitive structures, Toda lattice, transition from soliton to chaotic motion, nonlinear normal modes, noise perturbations of nonlinear dynamical systems, and phase locking of coupled limit cycle oscillators. Mathematical methods include Lie transforms, Monte Carlo simulations, stochastic calculus, perturbation methods and proper orthogonal decomposition. Applications include gyrodynamics, tether connected satellites, shell buckling, nonlinear circuits, volume oscillations of a large lake, systems with stick-slip friction, imperfect or disordered structures, overturning of rigid blocks, central pattern generators, flow induced oscillations, shape control and vibration suppression of elastic structures.All of these diverse contributions have a common thread: the world of nonlinear behavior. Although linear dynamics is an invaluable tool, there are many problems where nonlinear effects are essential. Some examples include bifurcation of solutions, stability of motion, the effects of large displacements, and subharmonic resonance. This book shows how nonlinear dynamics is currently being utilized and investigated. It will be of interest to engineers, applied mathematicians and physicists.
Download or read book Neuronal Dynamics written by Wulfram Gerstner and published by Cambridge University Press. This book was released on 2014-07-24 with total page 591 pages. Available in PDF, EPUB and Kindle. Book excerpt: This solid introduction uses the principles of physics and the tools of mathematics to approach fundamental questions of neuroscience.
Download or read book Pattern Formation and Dynamics in Nonequilibrium Systems written by Michael Cross and published by Cambridge University Press. This book was released on 2009-07-16 with total page 547 pages. Available in PDF, EPUB and Kindle. Book excerpt: An account of how complex patterns form in sustained nonequilibrium systems; for graduate students in biology, chemistry, engineering, mathematics, and physics.
Download or read book MATLAB for Neuroscientists written by Pascal Wallisch and published by Academic Press. This book was released on 2014-01-09 with total page 571 pages. Available in PDF, EPUB and Kindle. Book excerpt: MATLAB for Neuroscientists serves as the only complete study manual and teaching resource for MATLAB, the globally accepted standard for scientific computing, in the neurosciences and psychology. This unique introduction can be used to learn the entire empirical and experimental process (including stimulus generation, experimental control, data collection, data analysis, modeling, and more), and the 2nd Edition continues to ensure that a wide variety of computational problems can be addressed in a single programming environment. This updated edition features additional material on the creation of visual stimuli, advanced psychophysics, analysis of LFP data, choice probabilities, synchrony, and advanced spectral analysis. Users at a variety of levels—advanced undergraduates, beginning graduate students, and researchers looking to modernize their skills—will learn to design and implement their own analytical tools, and gain the fluency required to meet the computational needs of neuroscience practitioners. - The first complete volume on MATLAB focusing on neuroscience and psychology applications - Problem-based approach with many examples from neuroscience and cognitive psychology using real data - Illustrated in full color throughout - Careful tutorial approach, by authors who are award-winning educators with strong teaching experience
Download or read book Introductory Biophysics written by James R. Claycomb and published by Jones & Bartlett Learning. This book was released on 2011 with total page 375 pages. Available in PDF, EPUB and Kindle. Book excerpt: Designed for biology, physics, and medical students, Introductory Biophysics: Perspectives on the Living State, provides a comprehensive overview of the complex subject of biological physics. The companion CD-ROM, with MATLAB examples and the student version of QuickFieldTM, allows the student to perform biophysical simulations and modify the textbook example files. Included in the text are computer simulations of thermodynamics, astrobiology, the response of living cells to external fields, chaos in population dynamics, numerical models of evolution, electrical circuit models of cell suspension, gap junctions, and neuronal action potentials. With this text students will be able to perform biophysical simulations within hours. MATLAB examples include; the Hodgkin Huxley equations; the FitzHugh-Nagumo model of action potentials; fractal structures in biology; chaos in population dynamics; the cellular automaton model (the game of life); pattern formation in reaction-diffusion systems. QuickFieldTM tutorials and examples include; calculation of currents in biological tissue; cells under electrical stimulation; induced membrane potentials; heat transfer and analysis of stress in biomaterials.
Download or read book Hyperbolic Chaos written by Sergey P. Kuznetsov and published by Springer Science & Business Media. This book was released on 2012-03-20 with total page 318 pages. Available in PDF, EPUB and Kindle. Book excerpt: "Hyperbolic Chaos: A Physicist’s View” presents recent progress on uniformly hyperbolic attractors in dynamical systems from a physical rather than mathematical perspective (e.g. the Plykin attractor, the Smale – Williams solenoid). The structurally stable attractors manifest strong stochastic properties, but are insensitive to variation of functions and parameters in the dynamical systems. Based on these characteristics of hyperbolic chaos, this monograph shows how to find hyperbolic chaotic attractors in physical systems and how to design a physical systems that possess hyperbolic chaos. This book is designed as a reference work for university professors and researchers in the fields of physics, mechanics, and engineering. Dr. Sergey P. Kuznetsov is a professor at the Department of Nonlinear Processes, Saratov State University, Russia.
Download or read book Control and Nonlinearity written by Jean-Michel Coron and published by American Mathematical Soc.. This book was released on 2007 with total page 442 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book presents methods to study the controllability and the stabilization of nonlinear control systems in finite and infinite dimensions. The emphasis is put on specific phenomena due to nonlinearities. In particular, many examples are given where nonlinearities turn out to be essential to get controllability or stabilization. Various methods are presented to study the controllability or to construct stabilizing feedback laws. The power of these methods is illustrated by numerous examples coming from such areas as celestial mechanics, fluid mechanics, and quantum mechanics. The book is addressed to graduate students in mathematics or control theory, and to mathematicians or engineers with an interest in nonlinear control systems governed by ordinary or partial differential equations.
Download or read book Lectures on Fractal Geometry and Dynamical Systems written by Ya. B. Pesin and published by American Mathematical Soc.. This book was released on 2009 with total page 334 pages. Available in PDF, EPUB and Kindle. Book excerpt: Both fractal geometry and dynamical systems have a long history of development and have provided fertile ground for many great mathematicians and much deep and important mathematics. These two areas interact with each other and with the theory of chaos in a fundamental way: many dynamical systems (even some very simple ones) produce fractal sets, which are in turn a source of irregular 'chaotic' motions in the system. This book is an introduction to these two fields, with an emphasis on the relationship between them. The first half of the book introduces some of the key ideas in fractal geometry and dimension theory - Cantor sets, Hausdorff dimension, box dimension - using dynamical notions whenever possible, particularly one-dimensional Markov maps and symbolic dynamics. Various techniques for computing Hausdorff dimension are shown, leading to a discussion of Bernoulli and Markov measures and of the relationship between dimension, entropy, and Lyapunov exponents. In the second half of the book some examples of dynamical systems are considered and various phenomena of chaotic behaviour are discussed, including bifurcations, hyperbolicity, attractors, horseshoes, and intermittent and persistent chaos. These phenomena are naturally revealed in the course of our study of two real models from science - the FitzHugh - Nagumo model and the Lorenz system of differential equations. This book is accessible to undergraduate students and requires only standard knowledge in calculus, linear algebra, and differential equations. Elements of point set topology and measure theory are introduced as needed. This book is a result of the MASS course in analysis at Penn State University in the fall semester of 2008.
Download or read book Spiking Neuron Models written by Wulfram Gerstner and published by Cambridge University Press. This book was released on 2002-08-15 with total page 498 pages. Available in PDF, EPUB and Kindle. Book excerpt: Neurons in the brain communicate by short electrical pulses, the so-called action potentials or spikes. How can we understand the process of spike generation? How can we understand information transmission by neurons? What happens if thousands of neurons are coupled together in a seemingly random network? How does the network connectivity determine the activity patterns? And, vice versa, how does the spike activity influence the connectivity pattern? These questions are addressed in this 2002 introduction to spiking neurons aimed at those taking courses in computational neuroscience, theoretical biology, biophysics, or neural networks. The approach will suit students of physics, mathematics, or computer science; it will also be useful for biologists who are interested in mathematical modelling. The text is enhanced by many worked examples and illustrations. There are no mathematical prerequisites beyond what the audience would meet as undergraduates: more advanced techniques are introduced in an elementary, concrete fashion when needed.
Download or read book Modeling Life written by Alan Garfinkel and published by Springer. This book was released on 2017-09-06 with total page 456 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book develops the mathematical tools essential for students in the life sciences to describe interacting systems and predict their behavior. From predator-prey populations in an ecosystem, to hormone regulation within the body, the natural world abounds in dynamical systems that affect us profoundly. Complex feedback relations and counter-intuitive responses are common in nature; this book develops the quantitative skills needed to explore these interactions. Differential equations are the natural mathematical tool for quantifying change, and are the driving force throughout this book. The use of Euler’s method makes nonlinear examples tractable and accessible to a broad spectrum of early-stage undergraduates, thus providing a practical alternative to the procedural approach of a traditional Calculus curriculum. Tools are developed within numerous, relevant examples, with an emphasis on the construction, evaluation, and interpretation of mathematical models throughout. Encountering these concepts in context, students learn not only quantitative techniques, but how to bridge between biological and mathematical ways of thinking. Examples range broadly, exploring the dynamics of neurons and the immune system, through to population dynamics and the Google PageRank algorithm. Each scenario relies only on an interest in the natural world; no biological expertise is assumed of student or instructor. Building on a single prerequisite of Precalculus, the book suits a two-quarter sequence for first or second year undergraduates, and meets the mathematical requirements of medical school entry. The later material provides opportunities for more advanced students in both mathematics and life sciences to revisit theoretical knowledge in a rich, real-world framework. In all cases, the focus is clear: how does the math help us understand the science?
Download or read book Nonlinear Systems written by and published by BoD – Books on Demand. This book was released on 2018-07-18 with total page 264 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book focuses on several key aspects of nonlinear systems including dynamic modeling, state estimation, and stability analysis. It is intended to provide a wide range of readers in applied mathematics and various engineering disciplines an excellent survey of recent studies of nonlinear systems. With its thirteen chapters, the book brings together important contributions from renowned international researchers to provide an excellent survey of recent studies of nonlinear systems. The first section consists of eight chapters that focus on nonlinear dynamic modeling and analysis techniques, while the next section is composed of five chapters that center on state estimation methods and stability analysis for nonlinear systems.
Download or read book Mathematically Modelling The Electrical Activity Of The Heart From Cell To Body Surface And Back Again written by Pullan Andrew and published by World Scientific Publishing Company. This book was released on 2005-09-07 with total page 448 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book on modelling the electrical activity of the heart is an attempt to describe continuum based modelling of cardiac electrical activity from the cell level to the body surface (the forward problem), and back again (the inverse problem). Background anatomy and physiology is covered briefly to provide a suitable context for understanding the detailed modelling that is presented herein. The questions of what is mathematical modelling and why one would want to use mathematical modelling are addressed to give some perspective to the philosophy behind our approach. Our view of mathematical modelling is broad — it is not simply about obtaining a solution to a set of mathematical equations, but includes some material on aspects such as experimental and clinical validation.
