Download or read book The Experimental Determination of Solubilities written by G. T. Hefter and published by John Wiley & Sons. This book was released on 2003-08-01 with total page 657 pages. Available in PDF, EPUB and Kindle. Book excerpt: * Guidelines are provided on the reliability of various methods, as well as information for selecting the appropriate technique. * Unique coverage of the whole range of solubility measurements. * Very useful for investigators interested in embarking upon solubility measurements.

Download or read book The Experimental Determination of Solubilities written by G. T. Hefter and published by John Wiley & Sons. This book was released on 2003-11-14 with total page 658 pages. Available in PDF, EPUB and Kindle. Book excerpt: * Guidelines are provided on the reliability of various methods, as well as information for selecting the appropriate technique. * Unique coverage of the whole range of solubility measurements. * Very useful for investigators interested in embarking upon solubility measurements.

Download or read book Experimental Determination and Predictions of Gas Solubilities Using a Corresponding Structures Approach to the Radial Distribution Function written by Tsair-Wang Chung and published by . This book was released on 1993 with total page 378 pages. Available in PDF, EPUB and Kindle. Book excerpt:

Download or read book Experimental Determination of the Solubilities of Dissolver Off gas Constituents in a Kr 85 Recovery Solvent CCl sub 2 F sub 2 Final Report written by and published by . This book was released on 1983 with total page pages. Available in PDF, EPUB and Kindle. Book excerpt: The experimental determination of the solubility of the major off-gas constituent-Nitrogen was performed with a new solubility measurement apparatus. The new apparatus was designed, built and tested; an algorithm for thermodynamic consistency testing of P-T-x-y data for solubility systems was developed, and thermodynamically consistent Nitrogen-R-12 solubility data were taken. The Henry's Law constant for the Nitrogen-R-12 system can be represented by the equation ln H/sub N/sub 2/-R-12/ (atm) = 0.44 + 1.0708 lnT (/sup 0/K). The solubility data extend the range of known equilibrium data into a region where process equipment operate and are consistent with both other data at lower temperatures by other researchers and with regular solution theory.

Download or read book Experimental Determination of the Solubility of Small Organic Molecules in H2O and D2O and the Application of the Scaled Particle Theory to Aqueous and Nonaqueous Solutions written by Albert Armand Liabastre and published by . This book was released on 1974 with total page 454 pages. Available in PDF, EPUB and Kindle. Book excerpt:

Download or read book Experimental Determination of the Solubilities of Ethane in Selected N paraffin Solvents written by Michael Aaron Raff and published by . This book was released on 1989 with total page 272 pages. Available in PDF, EPUB and Kindle. Book excerpt:

Download or read book Carbon in Earth s Interior written by Craig E. Manning and published by John Wiley & Sons. This book was released on 2020-04-03 with total page 373 pages. Available in PDF, EPUB and Kindle. Book excerpt: Carbon in Earth's fluid envelopes - the atmosphere, biosphere, and hydrosphere, plays a fundamental role in our planet's climate system and a central role in biology, the environment, and the economy of earth system. The source and original quantity of carbon in our planet is uncertain, as are the identities and relative importance of early chemical processes associated with planetary differentiation. Numerous lines of evidence point to the early and continuing exchange of substantial carbon between Earth's surface and its interior, including diamonds, carbon-rich mantle-derived magmas, carbonate rocks in subduction zones and springs carrying deeply sourced carbon-bearing gases. Thus, there is little doubt that a substantial amount of carbon resides in our planet's interior. Yet, while we know it must be present, carbon's forms, transformations and movements at conditions relevant to the interiors of Earth and other planets remain uncertain and untapped. Volume highlights include: - Reviews key, general topics, such as carbonate minerals, the deep carbon cycle, and carbon in magmas or fluids - Describes new results at the frontiers of the field with presenting results on carbon in minerals, melts, and fluids at extreme conditions of planetary interiors - Brings together emerging insights into carbon's forms, transformations and movements through study of the dynamics, structure, stability and reactivity of carbon-based natural materials - Reviews emerging new insights into the properties of allied substances that carry carbon, into the rates of chemical and physical transformations, and into the complex interactions between moving fluids, magmas, and rocks to the interiors of Earth and other planets - Spans the various chemical redox states of carbon, from reduced hydrocarbons to zero-valent diamond and graphite to oxidized CO2 and carbonates - Captures and synthesizes the exciting results of recent, focused efforts in an emerging scientific discipline - Reports advances over the last decade that have led to a major leap forward in our understanding of carbon science - Compiles the range of methods that can be tapped tap from the deep carbon community, which includes experimentalists, first principles theorists, thermodynamic modelers and geodynamicists - Represents a reference point for future deep carbon science research Carbon in Planetary Interiors will be a valuable resource for researchers and students who study the Earth's interior. The topics of this volume are interdisciplinary, and therefore will be useful to professionals from a wide variety of fields in the Earth Sciences, such as mineral physics, petrology, geochemistry, experimentalists, first principles theorists, thermodynamics, material science, chemistry, geophysics and geodynamics.

Download or read book Experimental Determination of Solubilities of Sodium Tetraborate Borax in NaCl Solutions to High Ionic Strengths and Thermodynamics of NaB OH 4 aq written by and published by . This book was released on 2011 with total page 1 pages. Available in PDF, EPUB and Kindle. Book excerpt:

Download or read book Solubility in Supercritical Carbon Dioxide written by Ram B. Gupta and published by CRC Press. This book was released on 2006-12-06 with total page 960 pages. Available in PDF, EPUB and Kindle. Book excerpt: Supercritical fluid extraction is an environmentally safe and cost-effective alternative to traditional organic solvents. Carbon dioxide is widely used as the solvent of choice for applications such as caffeine and nicotine extraction due to its mild critical temperature, nontoxicity, nonflammability, and low cost. Introducing the most complete col

Download or read book Theoretical and Experimental Determination of the Hansen Solubility Parameters as Miscibility Predictors for the Formulation of Solid Dispersions written by Adriana De Simone and published by . This book was released on 2011 with total page 0 pages. Available in PDF, EPUB and Kindle. Book excerpt: During recent years the number of poorly soluble drug candidate has risen sharply and the formulation of poorly soluble compounds for oral delivery now presents one of the most frequent and greatest challenges to formulation scientist in pharmaceutical industry. One of the most attractive options for increasing the release rate is improvement of the solubility and dissolution rate utilizing amorphous forms of the drug and solid dispersion system. In this project GSK-X (BSC II) was employed as a drug model for the formulation of solid dispersion. The aim of this study was to determine the miscibility of drug model GSK-X (BSCII) and excipients to predict if glass solutions are likely to form when drug and polymer are formulated in a solid dispersion system. -- Estimation of drug/excipient miscibility was performed using Hansen solubility parameters (HSPs) which were determined experimentally by IGC and computationally using the HSPiP software. Due to poor agreement between the two sets of data, the solid dispersion-forming excipients were chosen on matching the HSPs determined experimentally by IGC. -- Solid state and physical chemical characterization of formulations prepared with 'good' polymers identified as poly(ethylene oxide) and poly(vinyl acetate) and 'bad' polymers such as poly(vinyl pyrrolidone) and Eudragit E 100 obtained by XRPD, MDSC and dissolution showed that experimental results were not in agreement with solubility parameter predictions. It was observed that the manufacturing process and the drug and polymer properties may limit the development of a successful formulation.

Download or read book Experimental Determination of Solubilities of Di calcium Ethylenediaminetetraacetic Acid Ca2C10H12N2O8 s in NaCl and MgCl2 Solutions to High Ionic Strengths and Its Pitzer Model written by and published by . This book was released on 2015 with total page 21 pages. Available in PDF, EPUB and Kindle. Book excerpt:

Download or read book Experimental Determination of Solubilities of Di calcium Ethylenediaminetetraacetic Acid Ca2C10H12N2O8 s in NaCl and MgCl2 Solutions to High Ionic Strengths and Its Pitzer Model written by and published by . This book was released on 2015 with total page 16 pages. Available in PDF, EPUB and Kindle. Book excerpt:

Download or read book Formulating Poorly Water Soluble Drugs written by Robert O. Williams III and published by Springer Nature. This book was released on 2022-05-19 with total page 701 pages. Available in PDF, EPUB and Kindle. Book excerpt: The objective of this third edition is to consolidate within a single text the most current knowledge, practical methods, and regulatory considerations pertaining to formulations development with poorly water-soluble molecules. A pharmaceutical scientist’s approach toward solubility enhancement of a poorly water-soluble molecule typically includes detailed characterization of the compound’s physiochemical properties, solid-state modifications, advanced formulation design, non-conventional process technologies, advanced analytical characterization, and specialized product performance analysis techniques. The scientist must also be aware of the unique regulatory considerations pertaining to the non-conventional approaches often utilized for poorly water-soluble drugs. One faced with the challenge of developing a drug product from a poorly soluble compound must possess at a minimum a working knowledge of each of the above mentioned facets and detailed knowledge of most. In light of the magnitude of the growing solubility problem to drug development, this is a significant burden especially when considering that knowledge in most of these areas is relatively new and continues to develop.

Download or read book Hansen Solubility Parameters written by Charles M. Hansen and published by CRC Press. This book was released on 2007-06-15 with total page 546 pages. Available in PDF, EPUB and Kindle. Book excerpt: Hansen solubility parameters (HSPs) are used to predict molecular affinities, solubility, and solubility-related phenomena. Revised and updated throughout, Hansen Solubility Parameters: A User's Handbook, Second Edition features the three Hansen solubility parameters for over 1200 chemicals and correlations for over 400 materials including p

Download or read book Water and CO2 Solubilities in Rhyolitic to Basaltic Melts written by Susanne Ohlhorst and published by . This book was released on 2002 with total page 109 pages. Available in PDF, EPUB and Kindle. Book excerpt:

Download or read book Developments and Applications in Solubility written by Trevor M Letcher and published by Royal Society of Chemistry. This book was released on 2007-10-31 with total page 433 pages. Available in PDF, EPUB and Kindle. Book excerpt: Solubility is fundamental to most areas of chemistry and is one of the most basic of thermodynamic properties. It underlies most industrial processes. Bringing together the latest developments and ideas, Developments and Applications in Solubility covers many varied and disparate topics. The book is a collection of work from leading experts in their fields and covers the theory of solubility, modelling and simulation, industrial applications and new data and recent developments relating to solubility. Of particular interest are sections on: experimental, calculated and predicted solubilities; solubility phenomena in 'green' quaternary mixtures involving ionic liquids; molecular simulation approaches to solubility; solubility impurities in cryogenic liquids and carbon dioxide in chemical processes. The book is a definitive and comprehensive reference to what is new in solubility and is ideal for researcher scientists, industrialists and academics

Download or read book Handbook of Solubility Data for Pharmaceuticals written by Abolghasem Jouyban and published by CRC Press. This book was released on 2009-08-26 with total page 554 pages. Available in PDF, EPUB and Kindle. Book excerpt: Aqueous solubility is one of the major challenges in the early stages of drug discovery. One of the most common and effective methods for enhancing solubility is the addition of an organic solvent to the aqueous solution. Along with an introduction to cosolvency models, the Handbook of Solubility Data for Pharmaceuticals provides an extensive datab