Download or read book The Effects of Cellular Transformation on Infection by Polyoma Virus written by Lynn Carol Klosowski and published by . This book was released on 1981 with total page 174 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Download or read book Polyomaviruses and Human Diseases written by Nasimul Ahsan and published by Springer Science & Business Media. This book was released on 2007-06-25 with total page 383 pages. Available in PDF, EPUB and Kindle. Book excerpt: Science never solves apr oblem without creating ten more Geor ge Bernard Shaw How prophetic the above words prove to be when applied to the advances of 20th century medicine. Prior to Banting and Best, chnicians were unaware of the ravages of diabetes, patients simply wasted away and died. Following the purifica tion of insulin, clinicians now had to deal with diabetic retinopathy, diabetic neph ropathy and all the other complications of long-term diabetes. A little over 50 years ago, the first successful human kidney transplant was performed in Boston. The first 30 years of the experience had successes when compared to the alternative but were a constant struggle to get even 50% of the grafts from deceased donors to survive more than a year. However, the science continued to advance knowledge of the immune response. With this came more and increasingly powerful tools for the clinician. Suddenly, success rates of 80-90% at one year were attainable. With this success came new problems, new complications and clinicians now had to worry about the long-term consequences of their therapy as patients were surviving with functional grafts for extended periods. A particular infectious complication evolved with the application of ever more powerful immunosuppressant drugs. Astute clinicians noted that occasionally cellular rejections seemed to get worse with steroids. Despite their best efforts and the use of powerful drugs, patients lost their grafts to overwhelming interstitial infiltrates not seen before.
Download or read book Transformation by Polyomavirus written by Hong-Hwa Chen and published by . This book was released on 1991 with total page 370 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Download or read book Molecular Virology of Human Pathogenic Viruses written by Wang-Shick Ryu and published by Academic Press. This book was released on 2016-03-30 with total page 441 pages. Available in PDF, EPUB and Kindle. Book excerpt: Molecular Virology of Human Pathogenic Viruses presents robust coverage of the key principles of molecular virology while emphasizing virus family structure and providing key context points for topical advances in the field. The book is organized in a logical manner to aid in student discoverability and comprehension and is based on the author's more than 20 years of teaching experience. Each chapter will describe the viral life cycle covering the order of classification, virion and genome structure, viral proteins, life cycle, and the effect on host and an emphasis on virus-host interaction is conveyed throughout the text. Molecular Virology of Human Pathogenic Viruses provides essential information for students and professionals in virology, molecular biology, microbiology, infectious disease, and immunology and contains outstanding features such as study questions and recommended journal articles with perspectives at the end of each chapter to assist students with scientific inquiries and in reading primary literature. - Presents viruses within their family structure - Contains recommended journal articles with perspectives to put primary literature in context - Includes integrated recommended reading references within each chapter - Provides access to online ancillary package inclusive of annotated PowerPoint images, instructor's manual, study guide, and test bank
Download or read book RNA Tumor Viruses Supplements and appendixes written by and published by . This book was released on 1984 with total page 1254 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Download or read book DNA Tumor Viruses written by Blossom Damania and published by Springer Science & Business Media. This book was released on 2008-12-19 with total page 805 pages. Available in PDF, EPUB and Kindle. Book excerpt: This unique book focuses on the DNA viruses in the human population that are associated with cancers. It covers most of the viruses that are thought to contribute to human malignancy. This book represents a comprehensive review of the field of DNA tumor virology. Right now, while there are books out there that cover individual viruses that are also covered in this book, there is no single book that covers this topic comprehensively. This book is the first current, comprehensive review of its kind in the market.
Download or read book Cellular Transforming Genes written by and published by . This book was released on 1986 with total page 4 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Download or read book Cell Transformation by Polyoma Virus in Vitro written by and published by . This book was released on 1970 with total page 506 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Download or read book Human Polyomaviruses written by Kamel Khalili and published by Wiley-Liss. This book was released on 2001-10-11 with total page 720 pages. Available in PDF, EPUB and Kindle. Book excerpt: Our understanding of human polyomaviruses has evolved profoundly in the last fifteen years, creating an urgent need for an updated resource. Drs. Khalili and Stoner have collected the contributions of renowned researchers and clinicians in this cutting-edge volume.
Download or read book Construction and Analysis of Mutations of the Polyoma Virus Medium T Antigen written by Dennis Templeton and published by . This book was released on 1983 with total page 338 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Download or read book Human Polyomaviruses written by Ugo Moens and published by Nova Science Pub Incorporated. This book was released on 2009 with total page 95 pages. Available in PDF, EPUB and Kindle. Book excerpt: Human polyomaviruses are non-enveloped viruses with a circular double-stranded DNA genome of approximately 5,000 base pairs. The members BK virus and JC virus were first isolated in 1971 and are very common in the human population. Simian virus 40 (SV40), although originally isolated from rhesus macaques and accidentally introduced in the human population during massive poliovirus vaccination, may represent a third member of the polyomaviruses that can have man as a natural host. Primary infection with BK or/and JC virus occurs during early childhood. Subsequently, these viruses establish a seemingly life-long harmless latent infection. However, virus reactivation can occur especially in immunocompromised individuals and JC virus has been recognised as the cause of progressive multifocal leukoencephalopathy, while BK virus-associated interstitial nephritis has become an emerging complication in renal transplant patients. The genomes of human polyomaviruses encode two functional classes of proteins: the regulatory proteins large T-antigen, small t-antigen, and agnoprotein, and the structural proteins VP1, VP2 and VP3 that form the capsid. The regulatory proteins can modulate the expression and/or activity of cellular proteins involved in signal transduction, cell cycle regulation, and chromosomal functions. Therefore, they all possess oncogenic potential. Consistent with this, human polyomaviruses are capable of transforming human cells and inducing tumours in rodents, and are implicated in human malignancies. This book focuses on the etiological role of human polyomaviruses in cancer and highlights the mechanisms by which the viral regulatory proteins may contribute to neoplastic transformation of the infected host cells. Possible therapeutic strategies against these viruses will also be discussed.
Download or read book Fenner and White s Medical Virology written by Christopher J. Burrell and published by Academic Press. This book was released on 2016-11-09 with total page 604 pages. Available in PDF, EPUB and Kindle. Book excerpt: Fenner and White's Medical Virology, Fifth Edition provides an integrated view of related sciences, from cell biology, to medical epidemiology and human social behavior. The perspective represented by this book, that of medical virology as an infectious disease science, is meant to provide a starting point, an anchor, for those who must relate the subject to clinical practice, public health practice, scholarly research, and other endeavors. The book presents detailed exposition on the properties of viruses, how viruses replicate, and how viruses cause disease. These chapters are then followed by an overview of the principles of diagnosis, epidemiology, and how virus infections can be controlled. The first section concludes with a discussion on emergence and attempts to predict the next major public health challenges. These form a guide for delving into the specific diseases of interest to the reader as described in Part II. This lucid and concise, yet comprehensive, text is admirably suited to the needs of not only advanced students of science and medicine, but also postgraduate students, teachers, and research workers in all areas of virology. Features updated and expanded coverage of pathogenesis and immunity Contains the latest laboratory diagnostic methods Provides insights into clinical features of human viral disease, vaccines, chemotherapy, epidemiology, and control
Download or read book Immunization Safety Review written by Institute of Medicine and published by National Academies Press. This book was released on 2003-12-26 with total page 118 pages. Available in PDF, EPUB and Kindle. Book excerpt: The Immunization Safety Review Committee was established by the Institute of Medicine (IOM) to evaluate the evidence on possible causal associations between immunizations and certain adverse outcomes, and to then present conclusions and recommendations. The committee's mandate also includes assessing the broader societal significance of these immunization safety issues. While all the committee members share the view that immunization is generally beneficial, none of them has a vested interest in the specific immunization safety issues that come before the group. The committee reviews three immunization safety review topics each year, addressing each one at a time. In this fifth report in a series, the committee examines the hypothesis that exposure to polio vaccine contaminated with simian virus 40 (SV40), a virus that causes inapparent infection in some monkeys, can cause certain types of cancer.
Download or read book Concepts in Viral Pathogenesis written by A. L. Notkins and published by Springer Science & Business Media. This book was released on 2012-12-06 with total page 418 pages. Available in PDF, EPUB and Kindle. Book excerpt: The current proliferation of scientific information makes it difficult for even the most diligent reader to keep up with the latest developments in his/her own field, let alone other areas of interest. Review articles are one solution, but they too have become so voluminous and detailed that they often defeat the purpose for which they were intended. We have attempted to ease this problem by using a different format. In this volume on Concepts in Viral Pathogenesis, we have assembled a series of mini-reviews/editorials, 1,000 to 2,000 words in length. Each is a pithy distil lation of the state-of-the-art with emphasis on current thinking and unifying concepts rather than a compendium of the literature. The 53 articles, all written by active workers in their respective fields, are organized systemati cally so that the book will provide busy investigators, teachers and students of up-to-date information in a very brief and easily read a conceptual core able form. In addition, the authors have attempted to identify unresolved problems and point to future directions.
Download or read book The Role of Polyoma Virus Small T antigen in Cell Transformation and Virus Replication written by David Isaac Dorsky and published by . This book was released on 1982 with total page 520 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Download or read book The Effect of Infection with Polyoma Virus on the Protein RNA and DNA of Mouse Embryo Cell Cultures written by Lawrence E. McConnehey and published by . This book was released on 1962 with total page 124 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Download or read book Host virus Interactions Critical for Cellular Transformation by Polyoma Virus and written by and published by . This book was released on 1980 with total page 10 pages. Available in PDF, EPUB and Kindle. Book excerpt:
