Download or read book The Development of New Preparation Methods for Surface Enhanced Raman Active Substrates written by William Scott Sutherland and published by . This book was released on 1990 with total page 402 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Download or read book Novel Approaches to Prepare and Utilize Surface enhanced Raman Spectroscopy SERS Substrates written by and published by . This book was released on 2008 with total page 185 pages. Available in PDF, EPUB and Kindle. Book excerpt: Over the past few decades, surface enhanced Raman spectroscopy (SERS) has garnered respect as an analytical technique with significant chemical and biological applications. SERS is important for the life sciences because it can provide trace level detection and a high level of molecular structure information. The development of quantitative, highly sensitive substrates requires control over size, shape, and position of metal nanoparticles which function as the SERS active medium. Thus, creating and successfully implementing a sensitive, reproducible, and robust SERS active substrate continues to be a challenging task. Its future development depends critically on techniques for lithography and nanofabrication. Herein, we report a novel method for SERS that is based upon using colloidal silver nanoparticles in a multiplexed microfluidics (MMFs) platform. The MMF is created in polydimethylsiloxane (PDMS) polymer material and used to perform parallel, high throughput, and sensitive detection/identification of single or various analytes under easily manipulated conditions. A facile passive pumping method is used to deliver samples into the channels under flowing conditions that are highly conducive for SERS measurments. Also an unconventional nanofabrication approach is modified to produce efficient SERS substrates. Metallic nanopatterns of silver discs are transferred from a stamp onto PDMS to create nanocomposite substrates with regular periodic morphologies. The stamp with periodic arrays of square, triangular, and elliptical pillars is created via Electron Beam Lithography of ma-N 2403 resist. A modified cyclodextrin is thermally evaporated on the stamp to overcome the adhesive nature of the ebeam resist and to function as a releasing layer. Subsequently, the stamp is over coated with Ag by physical vapor deposition at a controlled rate and thickness and used directly for nanotransfer printing (nTP). Stamps, substrates, and the efficiency of the nTP process were explored by SEM. Ag nano-disc-PDMS substrates are studied by SERS using Rhodamine 6G as the probe analyte. The SERS response of metallic nano-discs of various shapes/sizes on the original stamp is compared to the corresponding nTP substrates. We demonstrate that physical manipulation of the PDMS post nTP can be used to alter morphology. Additionally, stamps are shown to be reusable after the nTP process.
Download or read book Surface Enhanced Raman Scattering New Theoretical Approaches Materials and Strategies written by Ivano Alessandri and published by Frontiers Media SA. This book was released on 2020-03-25 with total page 175 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Download or read book Surface Enhanced Vibrational Spectroscopy written by Ricardo Aroca and published by John Wiley & Sons. This book was released on 2006-05-01 with total page 260 pages. Available in PDF, EPUB and Kindle. Book excerpt: Surface Enhanced Vibrational Spectroscopy (SEVS) has reached maturity as an analytical technique, but until now there has been no single work that describes the theory and experiments of SEVS. This book combines the two important techniques of surface-enhanced Raman scattering (SERS) and surface-enhanced infrared (SEIR) into one text that serves as the definitive resource on SEVS. Discusses both the theory and the applications of SEVS and provides an up-to-date study of the state of the art Offers interpretations of SEVS spectra for practicing analysts Discusses interpretation of SEVS spectra, which can often be very different to the non-enhanced spectrum - aids the practicing analyst
Download or read book Preparation of Surface enhanced Resonance Raman Scattering active Substrates written by Vicki L. Schlegel and published by . This book was released on 1990 with total page 528 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Download or read book Water soluble Vitamin Assays in Human Nutrition written by G.F.M. Ball and published by Springer. This book was released on 2012-11-05 with total page 0 pages. Available in PDF, EPUB and Kindle. Book excerpt: ...this is a valuable addition to the food analyst;s library. It brings together a well balanced account of the methods available an the literature cited will provide the analyst with all the details needed for setting up water-soluble vitamin assays and further reading to understand why these vitamins are important to those concerned with human nutrition. ' - International Journal of Food Science and Technology This book is of practical use as a tool and reference work of laboratory managers, senior analysts and laboratory technicians in food and vitamin manufactrurinf companies, for those in govenment and research institutes and for medical researchers, public analyst and nutritionist, It can also be recommended for a broad audience including lectures, students of natural sciences and food technologist. - lesbensm Wiss und Technol.'I recommend Water-soluble vitamins Assays in Human Nutrition not only to scientist in academia and industry and students in all food related fields as a valuable and easily used reference... it wll most likely be the first book I reach for when the inevitable question arises.April 1994Price: 115.00UK
Download or read book Application of Galvanic Displacement for the Preparation of Substrates for Surface enhanced Raman Spectroscopy written by Przemysław Roman Brejna and published by . This book was released on 2010 with total page 146 pages. Available in PDF, EPUB and Kindle. Book excerpt: Conditions that allow the production of substrates yielding high enhancement factors were optimized. Galvanic displacement was found to be a very convenient method of preparation of SERS-active substrates. The substrates give excellent enhancement and yet are easy to prepare, inexpensive and give very reproducible intensities for SERS spectra of thiol monolayers.
Download or read book Surface Enhanced Raman Scattering written by Zhong-Qun Tian and published by John Wiley & Sons Incorporated. This book was released on 2010-06-14 with total page 400 pages. Available in PDF, EPUB and Kindle. Book excerpt: Surface-Enhanced Raman Spectroscopy: Principles, Experiments, and Applications is a comprehensive, up to date, and balanced treatment of the theoretical and practical aspects of Surface-Enhanced Raman Scattering (SERS), a useful branch of spectroscopy for several areas of science. This book describes the basic principles of SERS, including SERS mechanisms, performing SERS measurements, and interpreting data. Also emphasized are applications in electrochemistry; catalysis; surface processing and corrosion; Self-Assemble-Layer and L-B Films; polymer science; biology; medicine and drug analysis; sensors; fuel cells; forensics; and archaeology. It is an essential guide for student and professional analytical chemists.
Download or read book Surface Enhanced Raman Scattering written by Katrin Kneipp and published by Springer Science & Business Media. This book was released on 2006-06-21 with total page 473 pages. Available in PDF, EPUB and Kindle. Book excerpt: Almost 30 years after the first reports on surface-enhanced Raman signals, the phenomenon of surface-enhanced Raman scattering (SERS) is now well established. SERS gained particular interest after single-molecule Raman spectroscopy had been demonstrated. This book summarizes and discusses present theoretical approaches that explain the phenomenon of SERS and reports on new and exciting experiments and applications of the fascinating spectroscopic effect.
Download or read book Fabrication of Surface Enhanced Raman Scattering Substrates by Controlled Assembly and Morphology Tuning of Gold Nanoparticles written by Agampodi Swarnapali De Silva Indrasekara and published by . This book was released on 2014 with total page 142 pages. Available in PDF, EPUB and Kindle. Book excerpt: The design and fabrication of nanoparticles (NPs) and NP assemblies to sustain intense electromagnetic field enhancement for surface enhanced Raman scattering (SERS)-based imaging and sensing have recently gained significant attention. In SERS, the intrinsic optical properties of plasmonic NPs are used to overcome the relatively low Raman cross-sections and thereby increase sensitivity. Sharp features in anisotropic NPs and interparticle gaps within NP assemblies have been identified as the locations where the highest SERS enhancements can be achieved, also known as "hot spots". Many attempts have been reported that deal with the bottom-up assembly of NPs to achieve highly reproducible, sensitive, and well characterized SERS substrates, but it still remains a challenge to attain monodisperse, highly reproducible "hot spots" and directional assembly. The focus of this dissertation is to develop synthetic protocols for controlled engineering of NPs with SERS "hot spots", and thereby to contribute to the advancement of SERS-based sensing and imaging applications. In this dissertation, the development of SERS substrates has evolved from dimers of spherical gold NPs (SP), to star-shaped gold NPs (ST), and finally to assembled superstructures of ST and SPs. The kinetically controlled assembly of SPs into dimers was achieved by using Raman active dithiolated linker molecules, with the highest yield reported for this method to the best of our knowledge, leading to SERS tags with a reproducible SERS enhancement on the order of 105. NP dimers, surface-functionalized to target U87 glioblastoma cancer cells, demonstrated a fast, reliable, and selective SERS-based detection of the diseased cells that outperforms fluorescence. The morphology of the STs was modified to possess longer and sharper spikes with a narrower tip curvature thereby increasing the electromagnetic field localization at the tips. SERS substrates were designed by periodically and reproducibly immobilizing STs on a planar substrate with high surface coverage and limited to no clustering, thus enabling femtomolar detection of organic analytes with an outstanding 109 SERS enhancement. Finally, the core-satellite assemblies of ST with SPs were achieved through conjugation linker chemistry. These assemblies demonstrated SERS enhancement of two orders of magnitudes greater than isolated STs thereby improving the sensitivity of potential SERS-based imaging and sensing applications.
Download or read book Development and Synthesis of Magneto optical Nanoparticle Substrates for Surface enhanced Raman Scattering SERS Applications written by Daniel Thomas Finley and published by . This book was released on 2008 with total page 144 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Download or read book Recent Developments In Plasmon supported Raman Spectroscopy 45 Years Of Enhanced Raman Signals written by Katrin Kneipp and published by World Scientific. This book was released on 2017-12-12 with total page 513 pages. Available in PDF, EPUB and Kindle. Book excerpt: Surface enhanced Raman scattering (SERS) might be one of the most impressive effects to demonstrate the power of plasmonic approaches in spectroscopy and became one of the 'triggers' for the rapidly emerging field of plasmonics.This book provides a review of some recent developments in SERS, such as tip enhanced Raman scattering (TERS), reports new experimental observations, sophisticated new SERS-active structures and substrates, new theoretical insight to explain the effect as well as exciting applications in various fields such as analytical science, biomedicine and nanotechnology.Written for graduate students and established researchers looking for inspiration for future work, its interdisciplinary nature makes the book suitable for readers in the fields of chemistry, physics, biology, medicine, nanotechnology and materials science.
Download or read book Developing Surface enhanced Raman Spectroscopy Substrates with Cell Membrane Patches for Material Identification written by 林牧謙 and published by . This book was released on 2022 with total page 0 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Download or read book Comprehensive Sampling and Sample Preparation written by Josep M. Bayona and published by Academic Press. This book was released on 2012-12-31 with total page 2998 pages. Available in PDF, EPUB and Kindle. Book excerpt: Comprehensive Sampling and Sample Preparation is a complete treatment of the theory and methodology of sampling in all physical phases and the theory of sample preparation for all major extraction techniques. It is the perfect starting point for researchers and students to design and implement their experiments and support those experiments with quality-reviewed background information. In its four volumes, fundamentals of sampling and sample preparation are reinforced through broad and detailed sections dealing with Biological and Medical, Environmental and Forensic, and Food and Beverage applications. The contributions are organized to reflect the way in which analytical chemists approach a problem. It is intended for a broad audience of analytical chemists, both educators and practitioners of the art and can assist in the preparation of courses as well in the selection of sampling and sample preparation techniques to address the challenges at hand. Above all, it is designed to be helpful in learning more about these topics, as well as to encourage an interest in sampling and sample preparation by outlining the present practice of the technology and by indicating research opportunities. Sampling and Sample preparation is a large and well-defined field in Analytical Chemistry, relevant for many application areas such as medicine, environmental science, biochemistry, pharmacology, geology, and food science. This work covers all these aspects and will be extremely useful to researchers and students, who can use it as a starting point to design and implement their experiments and for quality-reviewed background information There are limited resources that Educators can use to effectively teach the fundamental aspects of modern sample preparation technology. Comprehensive Sampling and Sample Preparation addresses this need, but focuses on the common principles of new developments in extraction technologies rather than the differences between techniques thus facilitating a more thorough understanding Provides a complete overview of the field. Not only will help to save time, it will also help to make correct assessments and avoid costly mistakes in sampling in the process Sample and sample preparation are integral parts of the analytical process but are often less considered and sometimes even completely disregarded in the available literature. To fill this gap, leading scientists have contributed 130 chapters, organized in 4 volumes, covering all modern aspects of sampling and liquid, solid phase and membrane extractions, as well as the challenges associated with different types of matrices in relevant application areas
Download or read book Surface Enhanced Raman Spectroscopy for Biophysical Applications written by Claudia Fasolato and published by Springer. This book was released on 2018-12-05 with total page 167 pages. Available in PDF, EPUB and Kindle. Book excerpt: The book explores the phenomenon of surface-enhanced Raman scattering (SERS), the huge amplification of Raman signal from molecules in the proximity of a metallic nanostructured surface, allowing readers to gain an in-depth understanding of the mechanisms affecting the spectroscopic response of SERS-active systems for effective applications. SERS spectroscopy is an ultrasensitive analytical technique with great potential for applications in the field of biophysics and nanomedicine. As examples, the author presents the design of nanocolloid-based SERS-active substrates for molecular sensing and of a folate-based SERS-active nanosensor capable of selectively interacting with cancer cells, enabling cancer diagnostics and therapy at the single-cell level. The author also suggests novel paths for the systematization of the SERS nanosystem design and experimental protocols to maximize sensitivity and reproducibility, which is essential when real-world biomedical applications are the goal of the study. With a combined approach, both fundamental and applied, and a detailed analysis of the state of the art, this book provides a valuable overview both for students new to SERS spectroscopy and for experts in the field.
Download or read book Surface Enhanced Raman Scattering written by Richard Chang and published by Springer Science & Business Media. This book was released on 2013-11-11 with total page 424 pages. Available in PDF, EPUB and Kindle. Book excerpt: In the course of the development of surface science, advances have been identified with the introduction of new diagnostic probes for analytical characterization of the adsorbates and microscopic structure of surfaces and interfaces. Among the most recently de veloped techniques, and one around which a storm of controversy has developed, is what has now been earmarked as surface enhanced Raman scattering (SERS). Within this phenomenon, molecules adsorbed onto metal surfaces under certain conditions exhibit an anomalously large interaction cross section for the Raman effect. This makes it possible to observe the detailed vibrational signature of the adsorbate in the ambient phase with an energy resolution much higher than that which is presently available in electron energy loss spectroscopy and when the surface is in contact with a much larger amount of material than that which can be tolerated in infrared absorption experiments. The ability to perform vibrational spectroscopy under these conditions would lead to a new understanding about the chemical identity, geome try, and bonding of adsorbed material at a level previously unacces sible. It is for these reasons that the last few years have brought an explosion of activity surrounding the exploitation of SERS. The search for the origines) of the anomalous enhancement has given rise to a research sub-activity of its own. Efforts to explain the en hancement have led to an increased understanding of the whole range of phenomena associated with the interaction of photons with adsor bates and metal surfaces.
Download or read book Principles of Surface Enhanced Raman Spectroscopy written by Eric Le Ru and published by Elsevier. This book was released on 2008-11-17 with total page 688 pages. Available in PDF, EPUB and Kindle. Book excerpt: SERS was discovered in the 1970s and has since grown enormously in breadth, depth, and understanding. One of the major characteristics of SERS is its interdisciplinary nature: it lies at the boundary between physics, chemistry, colloid science, plasmonics, nanotechnology, and biology. By their very nature, it is impossible to find a textbook that will summarize the principles needed for SERS of these rather dissimilar and disconnected topics. Although a basic understanding of these topics is necessary for research projects in SERS with all its many aspects and applications, they are seldom touched upon as a coherent unit during most undergraduate studies in physics or chemistry. This book intends to fill this existing gap in the literature. It provides an overview of the underlying principles of SERS, from the fundamental understanding of the effect to its potential applications. It is aimed primarily at newcomers to the field, graduate students, researchers or scientists, attracted by the many applications of SERS and plasmonics or its basic science. The emphasis is on concepts and background material for SERS, such as Raman spectroscopy, the physics of plasmons, or colloid science, all of them introduced within the context of SERS, and from where the more specialized literature can be followed. Represents one of very few books fully dedicated to the topic of surface-enhanced Raman spectroscopy (SERS) Gives a comprehensive summary of the underlying physical concepts around SERS Provides a detailed analysis of plasmons and plasmonics
