Download or read book The Development of a New Triphasic Oral Contraceptive written by R.B. Greenblatt and published by Springer Science & Business Media. This book was released on 2012-12-06 with total page 125 pages. Available in PDF, EPUB and Kindle. Book excerpt: R.B. GREENBLATT The original oral contraceptives contained more oestrogen in the form of ethinyloestradiol or mestranol and progestagen in the form of norethynodrel or norethisterone than was necessary f(x conception control. There has been a trend over the years to reduce dosages of both components in order to minimize side eHects while ensuring eflcctiveness. However, as dosages were lowered, there has been an increase in spotting and break through bleeding during the first few months of their adminis tration. The sequential pill appeared more physiological in that it followed more closely physiological principles, but the need to employ large doses ofEE or EE3ME to inhibit O\'ulation and the higher pregnancy rate made the sequential regimen less attrac ti\'e or useful. A triphasic formulation has become available that takes advantage of the synergism between ethinyloestradiol and the potent levonorgestrel so that low doses of the oestrogen and very low doses of the progestagen could be employed with great effectiveness. Such a preparation is relatively free from side effects, partly because the basic pharmacological tenet of the minimal dose for the desired result and the division of'the cycle into three parts using 30,lIg ofEE for the first 6 days, then:) days of 40,lIg, followed by 30,fIg for 10 da ys, for a total of21 days, thus more or less mimicking the physiological rise and fall of 125 THE DEVELOP:'IE:-;T OF, \ :-;E\\' TRIPH. \SIC OR.
Download or read book Hormonal Contraception and Post menopausal Hormonal Therapy written by IARC Working Group on the Evaluation of Carcinogenic Risks to Humans and published by World Health Organization. This book was released on 1999 with total page 692 pages. Available in PDF, EPUB and Kindle. Book excerpt: Evaluates evidence for an increased risk of cancer in women using combined oral contraceptives, progestogen-only hormonal contraceptives, post-menopausal estrogen therapy, and post-menopausal estrogen-progestogen therapy. Although the carcinogenicity of these preparations has been extensively investigated, the book stresses the many complex methodological issues that must be considered when interpreting findings and weighing results. Evidence of an association between use of these preparations and positive effects on health, including a reduced risk of some cancers, is also critically assessed. The first and most extensive monograph evaluates evidence of an association between the use of combined oral contraceptives and cancer at nine sites. Concerning breast cancer, the evaluation concludes that, even if the association is causal, the excess risk for breast cancer associated with patterns of use that are typical today is very small. Studies of predominantly high-dose preparations found an increased risk of hepatocellular carcinoma in the absence of hepatitis viruses. Citing these findings, the evaluation concludes that there is sufficient evidence in humans for the carcinogenicity of combined oral contraceptives. The evaluation also found sufficient evidence for the carcinogenicity of some, but not all, combined preparations in animals. Combined oral contraceptives were classified as carcinogenic to humans. The evaluation also cites conclusive evidence that these agents have a protective effect against cancers of the ovary and endometrium. Progestogen-only contraceptives are evaluated in the second monograph, which considers the association with cancer at six sites. The evaluation found no evidence of an increased risk for breast cancer. Although the evaluation found sufficient evidence in animals for the carcinogenicity of medroxyprogesterone acetate, evidence for the carcinogenicity of progestogen-only contraceptives in humans was judged inadequate. Progestogen-only contraceptives were classified as possibly carcinogenic to humans. The third monograph, on post-menopausal estrogen therapy, considers evidence of an association with cancer at eight sites. Findings from a large number of epidemiological studies indicate a small increase in the risk of breast cancer in women who have used these preparations for five years or more. Studies consistently show an association between use of post-menopausal estrogen therapy and an increased risk for endometrial cancer. Data on the association with other cancers were either inconclusive or suggested no effect on risk. The evaluation concludes that post-menopausal estrogen therapy is carcinogenic to humans. The final monograph evaluates the association between the use of post-menopausal estrogen-progestogen therapy and cancer at four sites. The evaluation of limited data on breast cancer found an increased relative risk observed with long-term use. Data were judged insufficient to assess the effects of past use and of different progestogen compounds, doses, and treatment schedules. For endometrial cancer, the evaluation found an increase in risk relative to non-users when the progestogen was added to the cycle for 10 days or fewer. Post-menopausal estrogen-progestogen therapy was classified as possibly carcinogenic to humans. Concerning post-menopausal therapy in general, the book notes that evidence of carcinogenic risks must be placed in perspective of potential benefits. The prevention of osteoporotic fractures is cited as the best-established benefit. Evidence also suggests that estrogen prevents heart disease and may prevent memory loss and dementia.
Download or read book Modern Oral Contraception written by Melinda Wallach and published by . This book was released on 2000 with total page 308 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Download or read book A New Triphasic Oral Contraceptive written by Ronald T. Burkman and published by . This book was released on 1992 with total page 52 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Download or read book Clinical Gynecology written by Eric J. Bieber and published by Cambridge University Press. This book was released on 2015-04-23 with total page 1127 pages. Available in PDF, EPUB and Kindle. Book excerpt: Written with the busy practice in mind, this book delivers clinically focused, evidence-based gynecology guidance in a quick-reference format. It explores etiology, screening, tests, diagnosis, and treatment for a full range of gynecologic health issues. The coverage includes the full range of gynecologic malignancies, reproductive endocrinology and infertility, infectious diseases, urogynecologic problems, gynecologic concerns in children and adolescents, and surgical interventions including minimally invasive surgical procedures. Information is easy to find and absorb owing to the extensive use of full-color diagrams, algorithms, and illustrations. The new edition has been expanded to include aspects of gynecology important in international and resource-poor settings.
Download or read book Sex Hormones Exercise and Women written by Anthony C. Hackney and published by Springer. This book was released on 2016-11-09 with total page 320 pages. Available in PDF, EPUB and Kindle. Book excerpt: It is well-established, through extensive peer-reviewed published research, that physical activity and exercise training can impact the reproductive endocrine system of women. This ground-breaking, comprehensive title presents a range of unique insights into the opposite question: how the reproductive endocrine system of women affects their exercise ability. More precisely, the thematic question explored in this work is: if exercise affects reproductive hormones, conversely then could the reproductive hormones have physiological effects unrelated to reproduction that influence the capacity of women to exercise? In exploring this question, the goal is to better understand the unique physiology of women and whether female sex hormones might account for some of the variance in physiological performance between amenorrheic and eumenorrheic women, and within women across the age span as they experience menarche to menopause. Sex Hormones, Exercise and Women: Scientific and Clinical Aspects synthesizes the research by exploring the physiology and psychology behind these occurrences. This novel title will not only be of interest to researchers, exercise scientists, graduate students, and clinicians; it will also serve as a source of valuable information for female athletes and their trainers in the context of preparing for competitions.
Download or read book Chalk Talks in Internal Medicine written by Somnath Mookherjee and published by Springer Nature. This book was released on 2020-09-30 with total page 347 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book provides teaching scripts for medical educators in internal medicine and coaches them in creating their own teaching scripts. Every year, thousands of attending internists are asked to train the next generation of physicians to master a growing body of knowledge. Formal teaching time has become increasingly limited due to rising clinical workload, medical documentation requirements, duty hour restrictions, and other time pressures. In addition, today’s physicians-in-training expect teaching sessions that deliver focused, evidence-based content that is integrated into clinical workflow. In keeping with both time pressures and trainee expectations, academic internists must be prepared to effectively and efficiently teach important diagnostic and management concepts. A teaching script is a methodical and structured plan that aids in effective teaching. The teaching scripts in this book anticipate learners’ misconceptions, highlight a limited number of teaching points, provide evidence to support the teaching points, use strategies to engage the learners, and provide a cognitive scaffold for teaching the topic that the teacher can refine over time. All divisions of internal medicine (e.g. cardiology, rheumatology, and gastroenterology) are covered and a section on undifferentiated symptom-based presentations (e.g. fatigue, fever, and unintentional weight loss) is included. This book provides well-constructed teaching scripts for commonly encountered clinical scenarios, is authored by experienced academic internists and allows the reader to either implement them directly or modify them for their own use. Each teaching script is designed to be taught in 10-15 minutes, but can be easily adjusted by the reader for longer or shorter talks. Teaching Scripts in Internal Medicine is an ideal tool for internal medicine attending physicians and trainees, as well as physician’s assistants, nurse practitioners, and all others who teach and learn internal medicine.
Download or read book The Handbook of Contraception written by Donna Shoupe and published by Springer Science & Business Media. This book was released on 2007-11-07 with total page 299 pages. Available in PDF, EPUB and Kindle. Book excerpt: I opened my series editor manuscript of The Handbook of Contraception: A Guide for Practical Management, edited by Drs. Donna Shoupe and Siri Kjos, on a tiny plane on the way to giving a lecture in Albany, NY. I expected to peruse the ma- script, and found that I could not put it down. The Handbook of Contraception: A Guide for Practical Management is an incredibly informative and enjoyable read. In keeping with the objective of this series for primary care clinicians, there is a quality in this title that is uncommon among medical textbooks. The chapters of this book are written with extraordinary intelligence and und- standing, and with attention to practical considerations in the selection and mana- ment of contraceptive options. The authors have reviewed the science behind contraception, including the chemical structure and effects of hormonal contraception, physiology of contraception, efficacy rates, and side effects, as well as the practical considerations that are relevant in helping patients choose between different cont- ceptive options. They do this with a clarity of language and intent that lets the book cover with sufficient detail the full range of questions that any primary care clinician will have regarding any of the traditional or new contraceptive options. Also included in each chapter is a section on “counseling tips,” which explicitly answers many of the questions that clinicians and their patients often have when discussing contraceptive options. For a book so useful and well done, the editors and authors deserve our thanks.
Download or read book Family Planning written by and published by JOHNS HOPKINS CCP - INFO. This book was released on 2007 with total page 388 pages. Available in PDF, EPUB and Kindle. Book excerpt: "United States Agency for International Development, Bureau for Global Health, Office of Population and Reproductive Health."
Download or read book The Handbook of Contraception written by Donna Shoupe and published by Springer Nature. This book was released on 2020-09-22 with total page 427 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book presents an up-to-date and comprehensive review of female contraception, offering an extensive overview of contraception types, including oral, injectable, emergency, and various cervical barrier contraceptives. It also discusses behavioral and sterilization methods of contraception as well as the clinical effectiveness, advantages, disadvantages, side effects, and mechanisms of action of each method. Now in its fully revised and expanded third edition, this text includes seven new chapters that address specific clinical issues that healthcare providers face daily. These issues include patients with medical problems, perimenopausal women, the adolescent population, post-pregnancy patients, patients with bleeding problems, fibroids or hyperplasia, obese patients and patients with acne or hirutism. There is also a new chapter dedicated to contraceptive methods that are currently in development. Each chapter reviews the correct use of the individual method, the most appropriate candidates, timing of initiation, red flag contraindications, risks and benefits, method of action, handling side effects, non-contraceptive benefits, switching methods and the CDC Medical Eligibility for the method. Importantly however, there is a new emphasis placed on standardized evidence-based practice recommendations incorporating the most recent US Selected Practice Recommendations and rationale as published by the US CDC. Written by experts in the field, The Handbook of Contraception, Third Edition, is a valuable resource for obstetricians, gynecologists, reproductive medicine specialists and primary care physicians.
Download or read book Medical Eligibility Criteria for Contraceptive Use written by and published by World Health Organization. This book was released on 2010 with total page 130 pages. Available in PDF, EPUB and Kindle. Book excerpt: Medical Eligibility Criteria for Contraceptive Use reviews the medical eligibility criteria for use of contraception, offering guidance on the safety and use of different methods for women and men with specific characteristics or known medical conditions. The recommendations are based on systematic reviews of available clinical and epidemiological research. It is a companion guideline to Selected Practice Recommendations for Contraceptive Use. Together, these documents are intended to be used by policy-makers, program managers, and the scientific community to support national programs in the preparation of service delivery guidelines. The fourth edition of this useful resource supersedes previous editions, and has been fully updated and expanded. It includes over 86 new recommendations and 165 updates to recommendations in the previous edition. Guidance for populations with special needs is now provided, and a new annex details evidence on drug interactions from concomitant use of antiretroviral therapies and hormonal contraceptives. To assist users familiar with the third edition, new and updated recommendations are highlighted. Everyone involved in providing family planning services and contraception should have the fourth edition of Medical Eligibility Criteria for Contraceptive Use at hand.
Download or read book Botanical Medicine for Women s Health E Book written by Aviva Romm and published by Elsevier Health Sciences. This book was released on 2017-01-25 with total page 671 pages. Available in PDF, EPUB and Kindle. Book excerpt: Use herbal medicines to treat women at any stage of life! Botanical Medicine for Women's Health, 2nd Edition provides an evidence-based, patient-centered approach to botanical interventions for many different medical conditions. More than 150 natural products are covered, showing their benefits in gynecologic health, fertility and childbearing, and menopausal health. This edition includes new full-color photos of herbal plants along with a discussion of the role of botanicals in healthy aging. Written by Aviva Romm, an experienced herbalist, midwife, and physician, this unique guide is an essential resource for everyday practice of herbal medicine. Winner of the 2010 American Botanical Council's James A. Duke Excellence in Botanical Literature Award! - Current, evidence-based information covers more than 150 botanicals for over 35 different conditions. - Case studies provide realistic scenarios and help you apply the content to the real world. - Treatment and formula boxes summarize the most important information. - Color illustrations and photographs of plants enable you to identify herbs visually as well as by substance make-up. - Logical chapter organization begins with the principles of herbal medicine and then covers women's health conditions organized chronologically by lifecycle, from teen and reproductive years to midlife and mature years. - Appendices include practical, at-a-glance information on common botanical names, chemical constituents of medicinal plants, and a summary table of herbs for women's health. - NEW! Updates reflect the latest research and the most current information. - NEW Full-color design and detailed, professional color photos of plants make this a unique, essential resource. - NEW! Coverage of the role of botanicals in healthy aging for women features phytoestrogens, Ayurvedic/Chinese herbs, and discussions of health promotion.
Download or read book A Clinical Guide for Contraception written by Leon Speroff and published by Lippincott Williams & Wilkins. This book was released on 2011 with total page 464 pages. Available in PDF, EPUB and Kindle. Book excerpt: The thoroughly updated Fifth Edition of this practical handbook provides the essential information that clinicians and patients need to choose the best contraceptive method for the patient's age and medical, social, and personal characteristics.
Download or read book Hepatotoxicity written by Hyman J. Zimmerman and published by Lippincott Williams & Wilkins. This book was released on 1999 with total page 850 pages. Available in PDF, EPUB and Kindle. Book excerpt: Written by the foremost authority in the field, this volume is a comprehensive review of the multifaceted phenomenon of hepatotoxicity. Dr. Zimmerman examines the interface between chemicals and the liver; the latest research in experimental hepatotoxicology; the hepatotoxic risks of household, industrial, and environmental chemicals; and the adverse effects of drugs on the liver. This thoroughly revised, updated Second Edition features a greatly expanded section on the wide variety of drugs that can cause liver injury. For quick reference, an appendix lists these medications and their associated hepatic injuries. Also included are in-depth discussions of drug metabolism and factors affecting susceptibility to liver injury.
Download or read book Sex Differences in Sports Medicine written by Ellen Casey, MD and published by Springer Publishing Company. This book was released on 2016-05-28 with total page 318 pages. Available in PDF, EPUB and Kindle. Book excerpt: This is the first book dedicated to the musculoskeletal, physiological, hormonal, and other differences between the sexes as they manifest in sports medicine. Organized anatomically from head to toe, this unique reference focuses on the sex-specific differences of men and women to inform clinical care and the management of common sports injuries. Other chapters cover nutrition, hormones, concussion, pain, sports cardiology and pulmonology, and the particular care of adolescent and geriatric patients. The editors have assembled a world-class team of specialists to collaborate on each chapter, and specially commissioned illustrations and tables help visualize the data and findings. While some books focus on “the female athlete” as a discrete category, this book discusses how the many physical stresses of athletics affect both sexes based on the inherent biological differences. The goal is to foster a more comprehensive understanding of the latest research and practice in sports medicine as it applies to all patients. As the field of sports medicine has grown exponentially over the last few decades, this book will serve as an essential resource for physicians, trainers, coaches, and anyone involved in athletics and medicine. Key Features: Provides an evidence-based review of how sex differences affect the risk of injury, presentation, and clinical course of sports-related injuries Anatomically based chapters highlight differences in static structures, dynamic movement, and pathology between the sexes Authors summarize key differences at the end of each chapter Includes special chapters on running and throwing, sports cardiology, sports pulmonology, nutrition, and unique athlete populations
Download or read book The Exercising Female written by Jacky Forsyth and published by Routledge. This book was released on 2018-09-28 with total page 288 pages. Available in PDF, EPUB and Kindle. Book excerpt: The Exercising Female: Science and Its Application is the first book to provide students, researchers, and professionals with an evidence-based reference on the exceptional scientific issues associated with female participation in sport and exercise. Based on the latest research, and treating women as a unique population, the book seeks to critically evaluate current debates, present the science underpinning female sport and exercise performance, and inform applied practice for the exercising female. Featuring contributions from leading scientists from around the world, and adopting a multidisciplinary approach—from exercise physiology, endocrinology, and biochemistry to psychology, biomechanics, and sociology—the book includes chapters on topics such as: Exercise and the menstrual cycle, contraception, pregnancy, motherhood, and menopause. Body image, exercise dependency, the psychology of sports performance, and homophobia in female sport. The Female Athlete Triad, bone health, musculoskeletal injury, and breast biomechanics. Nutritional requirements for the exercising female, immune function and exercise, and cardiovascular health. Filling a considerable gap in book literature around the science of female sport and exercise, this is crucial reading for any student studying female sport and exercise science, researchers of female sport, and any coach, sport scientist, strength and conditioning coach, sport psychologist, physician, or physiotherapist working with female athletes.
Download or read book Encyclopedic Reference of Molecular Pharmacology written by Stefan Offermanns and published by . This book was released on 2004 with total page 1152 pages. Available in PDF, EPUB and Kindle. Book excerpt: Presents current information on the molecular mechanisms of drug action. Provides 159 essays describing groups of drugs and drug targets. Several essays deal with general principles of pharmacology, such as drug tolerance, drug addiction, or drug metabolism.
