Download or read book Exercise Autophagy and Chronic Diseases written by Ning Chen and published by Springer Nature. This book was released on 2021-09-30 with total page 267 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book establishes a bridge between exercise-mediated functional status of autophagy and non-communicable chronic diseases for elucidating and clarifying the corresponding signal pathways and underlying mechanisms. The book consists of 13 chapters focusing on the in-depth discussion on signal pathways for regulating the functional status of autophagy for the prevention, treatment and rehabilitation of chronic diseases, the optimization of exercise intervention strategies for common and frequently-occurring chronic diseases, and the development of exercise mimetic pills for the persons with disability for exercise performance, or the persons without willing to exercise. This book is interesting and will be useful to a wide readership in the various fields of exercise science, exercise fitness, sports medicine, preventive medicine, and functional foods.

Download or read book Astrocytes in Patho Physiology of the Nervous System written by Vladimir Parpura and published by Springer Science & Business Media. This book was released on 2008-12-11 with total page 701 pages. Available in PDF, EPUB and Kindle. Book excerpt: Astrocytes were the original neuroglia that Ramón y Cajal visualized in 1913 using a gold sublimate stain. This stain targeted intermediate filaments that we now know consist mainly of glial fibrillary acidic protein, a protein used today as an astrocytic marker. Cajal described the morphological diversity of these cells with some ast- cytes surrounding neurons, while the others are intimately associated with vasculature. We start the book by discussing the heterogeneity of astrocytes using contemporary tools and by calling into question the assumption by classical neuroscience that neurons and glia are derived from distinct pools of progenitor cells. Astrocytes have long been neglected as active participants in intercellular communication and information processing in the central nervous system, in part due to their lack of electrical excitability. The follow up chapters review the “nuts and bolts” of ast- cytic physiology; astrocytes possess a diverse assortment of ion channels, neu- transmitter receptors, and transport mechanisms that enable the astrocytes to respond to many of the same signals that act on neurons. Since astrocytes can detect chemical transmitters that are released from neurons and can release their own extracellular signals there is an increasing awareness that they play physiological roles in regulating neuronal activity and synaptic transmission. In addition to these physiological roles, it is becoming increasingly recognized that astrocytes play critical roles during pathophysiological states of the nervous system; these states include gliomas, Alexander disease, and epilepsy to mention a few.

Download or read book Dorland s Dictionary of Medical Acronyms and Abbreviations written by Dorland and published by Elsevier Health Sciences. This book was released on 2015-07-24 with total page 481 pages. Available in PDF, EPUB and Kindle. Book excerpt: Medical acronyms and abbreviations offer convenience, but those countless shortcuts can often be confusing. Now a part of the popular Dorland's suite of products, this reference features thousands of terms from across various medical specialties. Its alphabetical arrangement makes for quick reference, and expanded coverage of symbols ensures they are easier to find. Effective communication plays an important role in all medical settings, so turn to this trusted volume for nearly any medical abbreviation you might encounter. - Symbols section makes it easier to locate unusual or seldom-used symbols. - Convenient alphabetical format allows you to find the entry you need more intuitively. - More than 90,000 entries and definitions. - Many new and updated entries including terminology in expanding specialties, such as Nursing; Physical, Occupational, and Speech Therapies; Transcription and Coding; Computer and Technical Fields. - New section on abbreviations to avoid, including Joint Commission abbreviations that are not to be used. - Incorporates updates suggested by the Institute for Safe Medication Practices (ISMP).

Download or read book Dictionary of Medical Acronyms and Abbreviations written by Stanley Jablonski and published by Hanley & Belfus. This book was released on 2004-09 with total page pages. Available in PDF, EPUB and Kindle. Book excerpt: This dictionary lists acronyms and abbreviations occurring with a reasonable frequency in the literature of medicine and the health care professions. Abbreviations and acronyms are given in capital letters, with no punctuation, and with concise definitions. The beginning sections also include symbols, genetic symbols, and the Greek alphabet and symbols.

Download or read book Principles of Immunopharmacology written by Frans P. Nijkamp and published by Springer Science & Business Media. This book was released on 2011-09-01 with total page 743 pages. Available in PDF, EPUB and Kindle. Book excerpt: This textbook provides a unique support in gaining essential knowledge on the immune response, its diagnosis and its modification by drugs and chemicals. The first section of the book, covering a basic introduction to immunology and its relevance for human disease, has been updated to accommodate new immunological concepts. The second section on immunodiagnostics has been further expanded to describe widely used molecular techniques and is followed by a systematic coverage of drugs affecting the immune system, revised to cover recent developments. The book concludes with a chapter on immunotoxicology. This third edition continues the unique format dealing with four related topics in a single volume, obviating the need to refer to several different textbooks. New aids to the reader include a two-column format, glossaries of technical terms and appendix reference tables. The emphasis on illustrations is maintained from the first edition.

Download or read book Transport ATPases written by Ernesto Carafoli and published by . This book was released on 1982 with total page 626 pages. Available in PDF, EPUB and Kindle. Book excerpt:

Download or read book Glucocorticoid Signaling written by Jen-Chywan Wang and published by Springer. This book was released on 2015-07-27 with total page 387 pages. Available in PDF, EPUB and Kindle. Book excerpt: This timely volume provides a comprehensive overview of glucocorticoids and their role in regulating many aspects of physiology and their use in the treatment of disease. The book is broken into four sections that begin by giving a general introduction to glucocorticoids and a brief history of the field. The second section will discuss the effects of glucocorticoids on metabolism, while the third section will cover the effects of glucocorticoids on key tissues. The final section will discuss general topics, such as animal models in glucocorticoid research and clinical implications of glucocorticoid research. Featuring chapters from leaders in the field, this volume will be of interest to both researchers and clinicians.

Download or read book Advances in Enzymology and Related Areas of Molecular Biology Volume 71 written by Alton Meister and published by Wiley-Interscience. This book was released on 1995-12-15 with total page 0 pages. Available in PDF, EPUB and Kindle. Book excerpt: Enzymes a revised frequently in modifying proteins for specialized uses. These books cover the latest advances in this field and its applications in the field of molecular biology.

Download or read book Pancreatitis written by John A. Williams and published by American Pancreatic Association. This book was released on 2016 with total page 0 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book provides comprehensive and definitive coverage of current understanding of the causes, diagnosis and treatment of the inflammatory disease pancreatitis. Pancreatitis occurs in both acute and chronic forms along with the more recently identified autoimmune pancreatitis. Mechanisms of the disease are studied in animal models with the goal of developing rational therapy. The book has been overseen and published by the American Pancreatic Association with John A. Williams as Editor-in-Chief. It includes 65 chapters written and edited by a worldwide group of authorities; completed chapters are also presented in open access on the Pancreapedia (www.pancreapedia.org). Individual chapters are relatively brief, dividing coverage into smaller units while maintaining depth. The book contains full-color and summary diagrams for enhanced readability, and a subject index enhances findability of information on specific topics. Pancreatitis is divided into four sections: - Experimental Pancreatitis - Section Editors: Stephen J. Pandol and Ashok K. Saluja - Acute Pancreatitis - Section Editors: Markus M. Lerch and Marc G. Besselink - Chronic Pancreatitis - Section Editors: Pramod K. Garg and Julia Mayerle - Autoimmune Pancreatitis - Section Editors: Suresh T. Chari and Phil A. Hart The book is aimed at pancreas researchers and clinical practitioners, but the clear and readable text will also appeal to students and individuals interested in the exocrine pancreas and its diseases.

Download or read book Liver Regeneration written by Dieter Häussinger and published by Walter de Gruyter. This book was released on 2011 with total page 233 pages. Available in PDF, EPUB and Kindle. Book excerpt: understanding the mechanisms involved in liver regeneration is of crucial importance for clinical medicine, not only regarding carcinogenesis and diabetes treatment, but also for the use of stem cells for cell therapy and liver surgery. This graduate-level text provides an overview of the current state of knowledge of the molecular mechanisms of liver regeneration. Hepatic stem cells are introduced and the important players involved in regeneration such as oval cells, bone marrow and stellate cells are reviewed. The cell signaling pathways that initiate liver regeneration and regulate the switch between proliferation and apoptosis are presented and the role of liver stem cells in tumorigenesis is discussed. The book also treats the epigenetic regulation of liver stem cells and the roles of inflammation and angiogenesis in liver regeneration. This compact overview of the fascinating regenerative capacity of the liver will be of interest to graduate students and post-docs in molecular biology, biochemistry and medicine.

Download or read book Advances in Mitochondrial Medicine written by Roberto Scatena and published by Springer Science & Business Media. This book was released on 2012-03-08 with total page 459 pages. Available in PDF, EPUB and Kindle. Book excerpt: Mitochondria are far more than the “powerhouse” of the cell as they have classically been described. In fact, mitochondria biological activities have progressively expanded to include not only various bioenergetic processes but also important biosynthetic pathways, calcium homeostasis and thermogenesis, cell death by apoptosis, several different signal transduction pathways mainly related to redox control of gene expression and so on. This functional and structural complexity may undergo important derangements so to justify the definition of ‘mitochondrial medicine’, which should include all the clinical consequences of congenital or acquired mitochondrial dysfunctions. There are actually a growing number of studies which assign a significant pathogenic role to damaged mitochondria in different diseases: ischemia/reperfusion injury, neurodegenerative diseases, cancer with its dramatic sequelae (i.e, metastasis), metabolic syndrome, hyperlipidemias, just to mention a few of the most important pathologies. In this context, a further aspect that should not be disregarded is the interaction of pharmacological agents with mitochondria, not only in regard of the toxicological aspects but, above all, of the potential therapeutic applications. In fact, it is interesting to note that, while the properties of different so-called “mitoxicants” are well-known, the subtle linkages between drugs and mitochondria is still in need of a real pharmacological and therapeutic control at the clinical level. This lack of consideration can often lead to an underestimation of unwanted toxic effects but also of desirable therapeutic activities. A reevaluation of the potential clinical role of mitochondria could give a new light on some yet obscure aspects of human pathophysiology.

Download or read book Role in Cell Physiology written by I.F. Pryme and published by Elsevier. This book was released on 1996-05-31 with total page 305 pages. Available in PDF, EPUB and Kindle. Book excerpt: This volume deals with functions of the cytoskeleton in different cellular processes such as cell compartmentation and organelle transport, secretion and cell attachment.

Download or read book Networking for Nerds written by Alaina G. Levine and published by John Wiley & Sons. This book was released on 2015-05-13 with total page 256 pages. Available in PDF, EPUB and Kindle. Book excerpt: Networking for Nerds provides a step-by-step guide to understanding how to access hidden professional opportunities through networking. With an emphasis on practical advice on how and why to network, you will learn how to formulate and execute a strategic networking plan that is dynamic, multidimensional, and leverages social media platforms and other networking channels. An invaluable resource for both established and early-career scientists and engineers (as well as networking neophytes!), Networking for Nerds offers concrete insight on crafting professional networks that are mutually beneficial and support the advancement of both your career goals and your scholarly ambitions. “Networking” does not mean going to one reception or speaking with a few people at one conference, and never contacting them again. Rather, “networking” involves a spectrum of activities that engages both parties, ensures everyone’s value is appropriately communicated, and allows for the exploration of a win-win collaboration of some kind. Written by award-winning entrepreneur and strategic career planning expert Alaina G. Levine, Networking for Nerds is an essential resource for anyone working in scientific and engineering fields looking to enhance their professional planning for a truly fulfilling, exciting, and stimulating career. professional planning for a truly fulfilling, exciting, and stimulating career.Networking for Nerds provides a step-by-step guide to understanding how to access hidden professionalopportunities through networking. With an emphasis on practical advice on how and why to network, youwill learn how to formulate and execute a strategic networking plan that is dynamic, multidimensional, andleverages social media platforms and other networking channels.An invaluable resource for both established and early-career scientists and engineers (as well as networkingneophytes!), Networking for Nerds offers concrete insight on crafting professional networks that aremutually beneficial and support the advancement of both your career goals and your scholarly ambitions.“Networking” does not mean going to one reception or speaking with a few people at one conference, andnever contacting them again. Rather, “networking” involves a spectrum of activities that engages bothparties, ensures everyone’s value is appropriately communicated, and allows for the exploration of a win-wincollaboration of some kind.Written by award-winning entrepreneur and strategic career planning expert Alaina G. Levine, Networking forNerds is an essential resource for anyone working in scientific and engineering fields looking to enhance theirprofessional planning for a truly fulfilling, exciting, and stimulating career.

Download or read book Goodman and Gilman s The Pharmacological Basis of Therapeutics written by Louis Sanford Goodman and published by MacMillan Publishing Company. This book was released on 1980 with total page 1916 pages. Available in PDF, EPUB and Kindle. Book excerpt: **** A classic text, now in its 50th year, recommended as a first purchase by Brandon-Hill. The new edition reflects the impact of modern biology since the previous edition in 1985: novel drugs produced by recombinant DNA technology, detailed knowledge of the structure and function of dozens of receptors, major progress in rational drug design, and improved treatment from appreciation of the importance of interplay between pharmacodynamics and pharmacokinetics. Annotation copyrighted by Book News, Inc., Portland, OR

Download or read book Lipid Mediated Signaling written by Eric J. Murphy and published by CRC Press. This book was released on 2010-03-05 with total page 454 pages. Available in PDF, EPUB and Kindle. Book excerpt: As the highly anticipated update to Lipid Second Messengers (CRC Press, 1999), Lipid-Mediating Signaling is a current and comprehensive overview of research methods used in lipid-mediated signal transduction. Pioneering experts provide a much-needed distillation of a decade's worth of advances in research techniques that are pertinent in understand

Download or read book New Prognostic and Predictive Markers in Cancer Progression written by Susan Costantini Alfredo Budillon and published by MDPI. This book was released on 2021-02-12 with total page 294 pages. Available in PDF, EPUB and Kindle. Book excerpt: Biomarkers are of critical medical importance for oncologists, allowing them to predict and detect disease and to determine the best course of action for cancer patient care. Prognostic markers are used to evaluate a patient’s outcome and cancer recurrence probability after initial interventions such as surgery or drug treatments and, hence, to select follow-up and further treatment strategies. On the other hand, predictive markers are increasingly being used to evaluate the probability of benefit from clinical intervention(s), driving personalized medicine. Evolving technologies and the increasing availability of “multiomics” data are leading to the selection of numerous potential biomarkers, based on DNA, RNA, miRNA, protein, and metabolic alterations within cancer cells or tumor microenvironment, that may be combined with clinical and pathological data to greatly improve the prediction of both cancer progression and therapeutic treatment responses. However, in recent years, few biomarkers have progressed from discovery to become validated tools to be used in clinical practice. This Special Issue comprises eight review articles and five original studies on novel potential prognostic and predictive markers for different cancer types.

Download or read book Protein Homeostasis written by Richard I. Morimoto and published by . This book was released on 2012 with total page 0 pages. Available in PDF, EPUB and Kindle. Book excerpt: Proper folding of proteins is crucial for cell function. Chaperones and enzymes that post-translationally modify newly synthesized proteins help ensure that proteins fold correctly, and the unfolded protein response functions as a homeostatic mechanism that removes misfolded proteins when cells are stressed. This book covers the entire spectrum of proteostasis in healthy cells and the diseases that result when control of protein production, protein folding, and protein degradation goes awry.