Download or read book The Biochemistry of Folic Acid and Related Pteridines written by Raymond L. Blakley and published by . This book was released on 1969 with total page 600 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Download or read book Chemistry and Biology of Pteridines and Folates written by June E. Ayling and published by Springer Science & Business Media. This book was released on 2012-12-06 with total page 806 pages. Available in PDF, EPUB and Kindle. Book excerpt: The pteridines in their multitude of forms fulfill many roles in nature ranging from pigments to cofactors for numerous redox and one-carbon transfer reactions. This extraordinary diversity of function is unified by the unique chemistry of the pteridine heterocycle. The International Symposium on the Chemistry and Biology of Pteridines and Folates is a forum for presenting recent and exciting advances in this expanding field. In of ideas results that has often stimulated bringing together various disciplines, a synergy fresh approaches to major problems. The Tenth International Symposium held at Orange Beach, Alabama, March 21-23, 1993, proved no exception by providing new insights into folate enzymology, tetrahydrobiopterin and molybdopterin biosynthesis and function, enzyme synthesis and regulation, along with novel synthetic strategies for producing compounds that will expedite further study. The many outstanding scientific contributions found in the following chapters, which represent the work presented at the Symposium, are a reflection of the significant advances made since the Ninth International Symposium held in Zurich in 1989. Since the 7th International Symposium in St. Andrews, Scotland, a tradition has evolved of honoring scientists who have made outstanding contributions to pteridine research with a Gowland Hopkins medal and lectureship. Sir Frederick Gowland Hopkins initiated the first investigation of what later proved to be pteridines in his studies of the yellow and white colors of butterflies.
Download or read book Chemistry and Biology of Pteridines 1989 written by Hans-Christoph Curtius and published by de Gruyter. This book was released on 1990 with total page 1390 pages. Available in PDF, EPUB and Kindle. Book excerpt: No detailed description available for "Zurich, Switzerland, September 3-8, 1989".
Download or read book Advances in Pharmacology and Chemotherapy written by and published by Academic Press. This book was released on 1981-01-12 with total page 338 pages. Available in PDF, EPUB and Kindle. Book excerpt: Advances in Pharmacology and Chemotherapy
Download or read book Folic Acid written by and published by National Academies. This book was released on 1977-01-01 with total page 312 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Download or read book Handbook of Experimental Pharmacology written by George H. Hitchings and published by . This book was released on 1983 with total page 457 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Download or read book Obesity and Lipotoxicity written by Ayse Basak Engin and published by Springer. This book was released on 2017-06-05 with total page 618 pages. Available in PDF, EPUB and Kindle. Book excerpt: Due to the resultant health consequences and considerable increase in prevalence, obesity has become a major worldwide health problem. “Obesity and Lipotoxicity” is a comprehensive review of the recent researches to provide a better understanding of the lipotoxicity-related mechanisms of obesity and the potential for the development of new treatment strategies. This book overviews the biochemical pathways leading to obesity-related metabolic disorders that occur subsequent to lipotoxicity. Chapters examine the deleterious effects of nutrient excess at molecular level including the cellular and molecular aspects of breast cancer, resistance to leptin, insulin, adiponectin, and interconnection between the circadian clock and metabolic pathways during high-fat feeding. “Lipotoxicity and Obesity” will be a useful resource for clinicians and basic science researchers, such as biochemists, toxicologists, immunologists, nutritionists, adult and pediatric endocrinologists, cardiologists, as well as students who are thought in this field.
Download or read book Development of Folates and Folic Acid Antagonists in Cancer Chemotherapy written by and published by . This book was released on 1987 with total page 258 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Download or read book Biochemistry of Brain written by Sudhir Kumar and published by Elsevier. This book was released on 2013-10-22 with total page 634 pages. Available in PDF, EPUB and Kindle. Book excerpt: Biochemistry of Brain is a collection of articles dealing with the developments in the biochemistry of the brain. This book gives a comprehensive and critical discussion of important developments in studies concerning the above subject. This text discusses the structure, function, and metabolism of glycosphingolipids, which are related to the study of sphingolipid storage diseases. Inborn defects of metabolism are found in Gaucher's and Fabry's disease, which are characterized by lipid accumulation in the brain. Another paper reviews the chemical and genetics of critically lysosomal hydrolase deficiencies that can cause the storage of sphingolipids. This book then explains the role of myelin basic protein in lipids in vivo that the weak bonding of the protein is not a major component of myelin stability. Another paper discusses the procedures for isolating subfractions of myelin and myelin-related membranes, with some attention given on the alterations in the subfractionation of myelin in pathological hypomyelinating and demyelinating conditions. Another article discusses the biochemical and enzymatic composition of lysosomes and the biosynthesis, intracellular transport, storage, and the degradation of lysosomal constituents. This collection of papers will benefit scientists doing research in microbiology, microchemistry, molecular genetics, and neurochemistry.
Download or read book Successful Drug Discovery Volume 1 written by János Fischer and published by John Wiley & Sons. This book was released on 2015-05-04 with total page 258 pages. Available in PDF, EPUB and Kindle. Book excerpt: The first volume of the book series "Successful Drug Discovery" is focusing on new drug discoveries during the last decade, from established drugs to recently introduced drugs of all kinds: small-molecule-, peptide-, and protein-based drugs. The role of serendipity is analyzed in some very successful drugs where the research targets of the lead molecule and the drug are different. Phenotypic and target-based drug discovery approaches are discussed from the viewpoint of pioneer drugs and analogues. This volume gives an excellent overview of insulin analogues including a discussion of the properties of rapid-acting and long-acting formulations of this important hormone. The major part of the book is devoted to case histories of new drug discoveries described by their key inventors. Eight case histories range across many therapeutic fields. The goal of this book series is to help the participants of the drug research community with a reference book series and to support teaching in medicinal chemistry with case histories and review articles of new drugs.
Download or read book Biochemical and Pharmacological Roles of Adenosylmethionine and the Central Nervous System written by Vincenzo Zappia and published by Elsevier. This book was released on 2013-10-22 with total page 185 pages. Available in PDF, EPUB and Kindle. Book excerpt: Biochemical and Pharmacological Roles of Adenosylmethionine and the Central Nervous System contains the proceedings of an International Round Table on Adenosylmethionine and the Central Nervous System held in Naples, Italy, on May 2, 1978. The papers explore the biochemical and pharmacological roles of S-adenosylmethionine (SAM), with particular emphasis on its functions in the central nervous system (CNS). This book consists of 13 chapters and opens with an introduction to some novel biochemical aspects of SAM and related sulfur compounds, paying particular attention to transmethylation reactions; polyamine biosynthesis and unusual biological roles of adenosylmethionine; metabolic pathways related to adenosine-sulfur compounds; and transport of adenosylmethionine. The following chapters discuss a number of chemical and biochemical properties of SAM as well as its pharmacological aspects within the CNS. The relation between folate and adenosylmethionine metabolism in the brain is examined, along with the effect of SAM administration on noradrenaline and serotonin metabolism in rat brain; cerebral utilization of adenosylmethionine and adenosylhomocysteine; and antidepressant effects of adenosylmethionine. Methylation in schizophrenia is also considered. This monograph will be a valuable source of information for biochemists and pharmacologists.
Download or read book Folate in Health and Disease written by Lynn B. Bailey and published by CRC Press. This book was released on 2009-11-24 with total page 602 pages. Available in PDF, EPUB and Kindle. Book excerpt: During the fifteen years since the bestselling first edition of Folate in Health and Disease was published, there have been thousands of new research studies related to folate and its role in health and disease. The second edition of the book uniquely bridges the gap between basic science and public health/clinical medicine.Presents Groundbreaking
Download or read book Pharmacology written by Miles Hacker and published by Academic Press. This book was released on 2009-06-19 with total page 607 pages. Available in PDF, EPUB and Kindle. Book excerpt: Pharmacology meets the rapidly emerging needs of programs training pharmacologic scientists seeking careers in basic research and drug discovery rather than such applied fields as pharmacy and medicine. While the market is crowded with many clinical and therapeutic pharmacology textbooks, the field of pharmacology is booming with the prospects of discovering new drugs, and virtually no extant textbook meets this need at the student level. The market is so bereft of such approaches that many pharmaceutical companies will adopt Hacker et al. to help train new drug researchers. The boom in pharmacology is driven by the recent decryption of the human genome and enormous progress in controlling genes and synthesizing proteins, making new and even custom drug design possible. This book makes use of these discoveries in presenting its topics, moving logically from drug receptors to the target molecules drug researchers seek, covering such modern topics along the way as side effects, drug resistance, pharmacogenomics, and even nutriceuticals, one in a string of culminating chapters on the drug discovery process. The book is aimed at advanced undergraduates and beginning graduate students in medical, pharmacy, and graduate schools looking for a solid introduction to the basic science of pharmacology and envisioning careers in drug research. - Uses individual drugs to explain molecular actions - Full color art program explains molecular and chemical concepts graphically - Logical structure reflecting the current state of pharmacology and translational research - Covers such intricacies as drug resistance and cell death - Consistent format across chapters and pedagogical strategies make this textbook a superior learning tool
Download or read book Recent Advances In Molecular And Biochemical Research On Proteins Proceedings Of The Iubmb Symposium On Protein Structure And Function written by Y H Wei and published by World Scientific. This book was released on 1994-01-14 with total page 297 pages. Available in PDF, EPUB and Kindle. Book excerpt: This monograph is edited on the basis of the lecture contents of invited speakers and some oral presentations at the IUBMB Symposium on Protein Structure and Function. The main theme was the molecular and biochemical studies on the structure and function of proteins. It covers the most recent advances in research on animal and bacterial toxins, plant enzymes and proteins, structural motifs and functional aspects of enzymes, biophysical and chemical characterizations of snake toxins by NMR spectroscopy, and molecular approaches for studying the structure-function relationship of proteins and enzymes. Most of the papers are based on data obtained in the authors' laboratory over the past few years and were written in a concise manner as review articles. They will be valuable reference for researchers and graduate students in this field of study.
Download or read book Nutritional Biochemistry written by Tom Brody and published by Academic Press. This book was released on 1999 with total page 1044 pages. Available in PDF, EPUB and Kindle. Book excerpt: This "real-world" approach allows students to come away with a realistically informed view of the basis for much of our understanding of nutritional biochemistry.
Download or read book NCI Monographs written by and published by . This book was released on 1986 with total page 268 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Download or read book Fortschritte der Chemie Organischer Naturstoffe Progress in the Chemistry of Organic Natural Products written by N. H. Andersen and published by Springer Science & Business Media. This book was released on 2012-12-06 with total page 702 pages. Available in PDF, EPUB and Kindle. Book excerpt: Mit Beiträgen zahlreicher Fachwissenschaftler
