Download or read book CRISPR Cas Enzymes written by and published by Academic Press. This book was released on 2019-01-25 with total page 454 pages. Available in PDF, EPUB and Kindle. Book excerpt: CRISPR-Cas Enzymes, Volume 616, the latest release in the Methods in Enzymology series, continues the legacy of this premier serial with quality chapters authored by leaders in the field. Topics covered in this release include CRISPR bioinformatics, A method for one-step assembly of Class 2 CRISPR arrays, Biochemical reconstitution and structural analysis of ribonucleoprotein complexes in Type I-E CRISPR-Cas systems, Mechanistic dissection of the CRISPR interference pathway in Type I-E CRISPR-Cas system, Site-specific fluorescent labeling of individual proteins within CRISPR complexes, Fluorescence-based methods for measuring target interference by CRISPR-Cas systems, Native State Structural Characterization of CRISRP Associated Complexes using Mass Spectrometry, and more. - Provides the authority and expertise of leading contributors from an international board of authors - Presents the latest release in the Methods in Enzymology series - Updated release includes the latest information on the CRISPR-Cas Enzymes

Download or read book Biochemistry of Copper written by Maria C. Linder and published by Springer Science & Business Media. This book was released on 2013-11-21 with total page 534 pages. Available in PDF, EPUB and Kindle. Book excerpt: Copper has long been known as essential to living systems, in part through its fundamental role in electron transport and respiration. Over the years into the present, its involvement in an ever increasing number of processes in all kinds of organisms has become apparent, and new and exciting vistas of its roles in such areas as the central nervous system, and in humoral functions, are appearing on the horizon. Although the biochemistry of this element has not been studied nearly as much as that of many others, a for midable amount of work has been carried out. It has thus been a challenge to produce a summary of what has been found that provides both breadth and depth. My goal has been to try to be as comprehensive as possible, within some limitations. I have tried to provide basic information and basic data that should continue to be useful for a long time. The goal has also been to interpret where we currently stand in our knowledge of the structure, function, regulation, and metabolism of Cu-dependent processes and sub stances, especially proteins. Thus, I have tried to make this a source book for historic as well as current information on all aspects of copper bio chemistry, and a summary of our current knowledge of copper-dependent proteins and processes. Most of the research on copper has been carried out on vertebrates, especially mammals. This has played a role in the organization of the book.

Download or read book All About Albumin written by Theodore Peters Jr. and published by Academic Press. This book was released on 1995-12-21 with total page 455 pages. Available in PDF, EPUB and Kindle. Book excerpt: The first of its kind, All About Albumin summarizes the chemistry, genetics, metabolism, clinical implications, and commercial aspects of albumin. It provides the most up-to-date sequences, structures, and compositions of many species, and includes more than 2000 references. - Includes up-to-date sequences, structures, and compositions of many species - Reviews the protein chemistry, genetic control, and metabolism of albumin - Covers medical and cell culture applications in vivo and in vitro, with a section on handling albumin in the laboratory - Presents the relationship of albumin to its superfamily with an updated scheme for their evolution - First complete coverage of all aspects of serum albumin in one volume, with more than 2000 references

Download or read book Molecular Biology of the Cell written by and published by . This book was released on 2002 with total page 0 pages. Available in PDF, EPUB and Kindle. Book excerpt:

Download or read book Biochemistry of Nickel written by Robert P. Hausinger and published by Springer Science & Business Media. This book was released on 2013-06-29 with total page 286 pages. Available in PDF, EPUB and Kindle. Book excerpt: In this timely monograph, the author summarizes the rapidly growing body of knowledge regarding nickel by providing a balanced discussion of its harmful and beneficial effects. Coverage includes a history of nickel; the chemistry of nickel, descriptions of the four known enzymes which contain nickel; and nickel metabolism in microbes, plants, and animals. Taken as a whole, Dr. Hausinger's work will highlight key features of this important element and help define future research.

Download or read book The Biochemical Journal written by and published by . This book was released on 1927 with total page 700 pages. Available in PDF, EPUB and Kindle. Book excerpt: Vols. 36- include Proceedings of the Biochemical Society.

Download or read book Exploring the Biological Contributions to Human Health written by Institute of Medicine and published by National Academies Press. This book was released on 2001-07-02 with total page 287 pages. Available in PDF, EPUB and Kindle. Book excerpt: It's obvious why only men develop prostate cancer and why only women get ovarian cancer. But it is not obvious why women are more likely to recover language ability after a stroke than men or why women are more apt to develop autoimmune diseases such as lupus. Sex differences in health throughout the lifespan have been documented. Exploring the Biological Contributions to Human Health begins to snap the pieces of the puzzle into place so that this knowledge can be used to improve health for both sexes. From behavior and cognition to metabolism and response to chemicals and infectious organisms, this book explores the health impact of sex (being male or female, according to reproductive organs and chromosomes) and gender (one's sense of self as male or female in society). Exploring the Biological Contributions to Human Health discusses basic biochemical differences in the cells of males and females and health variability between the sexes from conception throughout life. The book identifies key research needs and opportunities and addresses barriers to research. Exploring the Biological Contributions to Human Health will be important to health policy makers, basic, applied, and clinical researchers, educators, providers, and journalists-while being very accessible to interested lay readers.

Download or read book The Biochemical Journal written by and published by . This book was released on 1961 with total page 816 pages. Available in PDF, EPUB and Kindle. Book excerpt:

Download or read book Biochemistry of Antimicrobial Action written by Trevor John Franklin and published by Springer. This book was released on 2013-11-11 with total page 235 pages. Available in PDF, EPUB and Kindle. Book excerpt: The rapid advances made in the study of the synthesis, structure and function of biological macromolecules in the last fifteen years have enabled scientists concerned with antimicrobial agents to achieve a considerable measure of understanding of how these substances inhibit cell growth and division. The use of antimicrobial agents as highly specific inhibitors has in turn substantially assisted the investigation of complex biochemical processes. The literature in this field is so extensive however, that we considered an attempt should be made to draw together in an introductory book the more significant studies of recent years. This book, which is in fact based on lecture courses given by us to undergraduates at Liverpool and Manchester Universities, is therefore intended as an introduction to the biochemistry of antimicrobial action for advanced students in many disciplines. We hope that it may also be useful to established scientists who are new to this area of research. The book is concerned with a discussion of medically important antimicrobial compounds and also a number of agents that, although having no medical uses, have proved invaluable as research tools in biochemistry. Our aim has been to present the available information in a simple and readable way, emphasizing the established facts rather than more controversial material. Whenever possible, however, we have indicated the gaps in the present knowledge of the subject where further information is required.

Download or read book Collected Papers written by University College, London. Dept. of Physiology and Biochemistry and published by . This book was released on 1915 with total page 372 pages. Available in PDF, EPUB and Kindle. Book excerpt:

Download or read book Laboratory Guide to the Methods in Biochemical Genetics written by Nenad Blau and published by Springer Science & Business Media. This book was released on 2008-05-31 with total page 860 pages. Available in PDF, EPUB and Kindle. Book excerpt: This manual deals specifically with laboratory approaches to diagnosing inborn errors of metabolism. The key feature is that each chapter is sufficiently detailed so that any individual can adopt the described method into their own respective laboratory.

Download or read book Environmental Epigenetics written by L. Joseph Su and published by Springer. This book was released on 2015-05-18 with total page 327 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book examines the toxicological and health implications of environmental epigenetics and provides knowledge through an interdisciplinary approach. Included in this volume are chapters outlining various environmental risk factors such as phthalates and dietary components, life states such as pregnancy and ageing, hormonal and metabolic considerations and specific disease risks such as cancer cardiovascular diseases and other non-communicable diseases. Environmental Epigenetics imparts integrative knowledge of the science of epigenetics and the issues raised in environmental epidemiology. This book is intended to serve both as a reference compendium on environmental epigenetics for scientists in academia, industry and laboratories and as a textbook for graduate level environmental health courses. Environmental Epigenetics imparts integrative knowledge of the science of epigenetics and the issues raised in environmental epidemiology. This book is intended to serve both as a reference compendium on environmental epigenetics for scientists in academia, industry and laboratories and as a textbook for graduate level environmental health courses.

Download or read book Biochemical Imbalances in Disease written by Ann Woodriff Beirne and published by Singing Dragon. This book was released on 2010-10-15 with total page 396 pages. Available in PDF, EPUB and Kindle. Book excerpt: Biochemical imbalances caused by nutritional deficiencies are a contributory factor in chronic illnesses such as cardiovascular disease, diabetes, auto-immune conditions and cancer. This handbook for practitioners explains how to identify and treat such biochemical imbalances in order to better understand and manage a patient's ill-health. The book examines a range of biochemical imbalances, including compromised adrenal or thyroid function, gastro-intestinal imbalances, immune system problems and sex hormone imbalances, and explains how and why such states occur. It pulls together a wide range of evidence to show how such imbalances are involved in the most common chronic diseases. It helps practitioners to understand how to identify the imbalances through appropriate case history taking and laboratory testing, and how to design and implement effective nutritional interventions. Developed by leading academics and practitioners in the fields of nutritional therapy and functional medicine, this evidence-informed approach can be used with all patients who present in clinic, regardless of whether or not they have a 'named medical condition'. In the final chapter, a case example illustrates how to use the theoretical information in the practice of treating patients with chronically compromised health. Biochemical Imbalances in Disease is an essential text for nutritional therapy practitioners, as well as for students, and will be welcomed by complementary and conventional healthcare practitioners alike.

Download or read book Essentials of Glycobiology written by Ajit Varki and published by CSHL Press. This book was released on 1999 with total page 694 pages. Available in PDF, EPUB and Kindle. Book excerpt: Sugar chains (glycans) are often attached to proteins and lipids and have multiple roles in the organization and function of all organisms. "Essentials of Glycobiology" describes their biogenesis and function and offers a useful gateway to the understanding of glycans.

Download or read book Clinical Biochemistry written by William J. Marshall and published by Elsevier Health Sciences. This book was released on 2008-01-01 with total page 997 pages. Available in PDF, EPUB and Kindle. Book excerpt: Now fully revised and updated, Clinical Biochemistry, third edition is essential reading for specialty trainees, particularly those preparing for postgraduate examinations. It is also an invaluable current reference for all established practitioners, including both medical and scientist clinical biochemists. Building on the success of previous editions, this leading textbook primarily focuses on clinical aspects of the subject, giving detailed coverage of all conditions where clinical biochemistry is used in diagnosis and management - including nutritional disorders, diabetes, inherited metabolic disease, metabolic bone disease, renal calculi and dyslipidaemias. The acquisition and interpretation of clinical biochemical data are also discussed in detail. Expanded sections on haematology and immunology for clinical biochemists provide a thorough understanding of both laboratory and clinical aspects New chapters are included on important evolving areas such as the metabolic response to stress, forensic aspects of clinical biochemistry and data quality management An extended editorial team - including three expert new additions - ensures accuracy of information and relevance to current curricula and clinical practice A superb new accompanying electronic version provides an enhanced learning experience and rapid reference anytime, anywhere! Elsevier ExpertConsult.com Enhanced eBooks for medical professionals Compatible with PC, Mac®, most mobile devices and eReaders, browse, search, and interact with this title - online and offline. Redeem your PIN at expertconsult.com today! Straightforward navigation and search across all Elsevier titles Seamless, real-time integration between devices Adjustable text size and brightness Notes and highlights sharing with other users through social media Interactive content

Download or read book Explaining Photosynthesis written by Kärin Nickelsen and published by Springer. This book was released on 2015-06-17 with total page 354 pages. Available in PDF, EPUB and Kindle. Book excerpt: Recounting the compelling story of a scientific discovery that took more than a century to complete, this trail-blazing monograph focuses on methodological issues and is the first to delve into this subject. This book charts how the biochemical and biophysical mechanisms of photosynthesis were teased out by succeeding generations of scientists, and the author highlights the reconstruction of the heuristics of modelling the mechanism—analyzed at both individual and collective levels. Photosynthesis makes for an instructive example. The first tentative ideas were developed by organic chemists around 1840, while by 1960 an elaborate proposal at a molecular level, for both light and dark reactions, was established. The latter is still assumed to be basically correct today. The author makes a persuasive case for a historically informed philosophy of science, especially regarding methodology, and advocates a history of science whose narrative deploys philosophical approaches and categories. She shows how scientists’ attempts to formulate, justify, modify, confirm or criticize their models are best interpreted as series of coordinated research actions, dependent on a network of super- and subordinated epistemic goals, and guided by recurrent heuristic strategies. With dedicated chapters on key figures such as Otto Warburg, who borrowed epistemic fundamentals from other disciplines to facilitate his own work on photosynthesis, and on more general topics relating to the development of the field after Warburg, this new work is both a philosophical reflection on the nature of scientific enquiry and a detailed history of the processes behind one of science’s most important discoveries.

Download or read book An Introduction to Computational Biochemistry written by C. Stan Tsai and published by John Wiley & Sons. This book was released on 2003-03-31 with total page 381 pages. Available in PDF, EPUB and Kindle. Book excerpt: This comprehensive text offers a solid introduction to the biochemical principles and skills required for any researcher applying computational tools to practical problems in biochemistry. Each chapter includes an introduction to the topic, a review of the biological concepts involved, a discussion of the programming and applications used, key references, and problem sets and answers. Providing detailed coverage of biochemical structures, enzyme reactions, metabolic simulation, genomic and proteomic analyses, and molecular modeling, this is the perfect resource for students and researchers in biochemistry, bioinformatics, bioengineering and computational science.