Download or read book Journal of the National Cancer Institute written by and published by . This book was released on 2000-05 with total page 410 pages. Available in PDF, EPUB and Kindle. Book excerpt:

Download or read book Cells Aging and Human Disease written by Michael B. Fossel M.D. and published by Oxford University Press. This book was released on 2004-06-10 with total page 504 pages. Available in PDF, EPUB and Kindle. Book excerpt: Cells, Aging, and Human Disease is the first book to explore aging all the way from genes to clinical application, analyzing the fundamental cellular changes which underlie human age-related disease. With over 4,000 references, this text explores both the fundamental processes of human aging and the tissue-by-tissue pathology, detailing both breaking research and current state-of-the-art clinical interventions in aging and age-related disease. Far from merely sharing a common onset late in the lifespan, age-related diseases are linked by fundamental common characteristics at the genetic and cellular levels. Emphasizing human cell mechanisms, the first section presents and analyzes our current knowledege of telomere biology and cell senescence. In superb academic detail, the text brings the reader up to date on telomere maintenance, telomerase dynamics, and current research on cell senescence--and the general model--cell senescence as the central component in human senescence and cancer. For each human malignancy, the chapter reviews and analyzes all available data on telomeres and telomerase, as well as summarizing current work on their clinical application in both diagnosis and cancer therapy. The second edition, oriented by organs and tissues, explores the actual physiological impact of cell senescence and aging on clinical disease. After a summary of the literature on early aging syndromes--the progerias--the text reviews aging diseases (Alzheimer's dementia, osteoarthritis, atherosclerosis, immune aging, presbyopia, sarcopenia, etc.) in the context of the tissues in which they occur. Each of the ten clinical chapters--skin, cardiovascular system, bone and joints, hematopoetic and immune systems, endocrine, CNS, renal, muscle, GI, and eyes--examines what we know of their pathology, the role of cell sensescence, and medical interventions, both current and potential.

Download or read book Hormonal Carcinogenesis III written by Jonathan J. Li and published by Springer Science & Business Media. This book was released on 2012-12-06 with total page 610 pages. Available in PDF, EPUB and Kindle. Book excerpt: Since our previous symposium in 1995, the pace of research in hormones and cancer has accelerated. Progress in our understanding of hormonal carcinogenic processes has been a direct result of the advances made in cell biology, endocrinology, and carcinogenesis at the molecular level. The newer fields of molecular genetics and cytogenetics already have and are expected to continue to playa major role in furthering our understanding of the cellular and molecular events in hormonal carcinogenesis. It has become increasingly clear that the risk of naturally occurring sex hormones in carcinogenic processes, both in human and in animal models, requires only minute quantities of hormones, at both the serum and tissue levels. Moreover, hormone target tissues for neoplastic transformation, perhaps with the exception of the liver, generally have relatively modest ability to metabolize sex hormones, such as the breast and prostate. Table 1 summarizes the serum, and in most cases, the tissue levels of sex hormones, both endogenously and exogenously ingested, which are associated with increased risk for endocrine-associated cancers such as breast, endometrium, and prostate, as well as the hormone levels of four experimental models that have been shown to elicit high tumor incidences. In contrast to the human, in which the hormone levels are cyclic, however, the latter require continuous hormone exposure at these relatively low levels.

Download or read book Annual Plan for Fiscal Year written by National Toxicology Program (U.S.) and published by . This book was released on 1995 with total page 622 pages. Available in PDF, EPUB and Kindle. Book excerpt:

Download or read book Metalloproteinases as Targets for Anti Inflammatory Drugs written by Kevin M.K. Bottomley and published by Springer. This book was released on 2012-12-06 with total page 214 pages. Available in PDF, EPUB and Kindle. Book excerpt: This volume describes recent research in the field of metalloproteinases (a family of enzymes that can catalyze tissue degradation), in particular their participation in autoimmune diseases such as rheumatoid arthritis, reviewing the latest developments in metalloproteinase inhibitor design and the current status of clinical candidates. This volume is intended not only for those active in research into metalloproteinases but also for those with an interest in inflammatory diseases. Thus it addresses both academic and industrial researchers.

Download or read book Cancer Research written by and published by . This book was released on 1999 with total page 1040 pages. Available in PDF, EPUB and Kindle. Book excerpt:

Download or read book Environmental Health Perspectives written by and published by . This book was released on 2004 with total page 1252 pages. Available in PDF, EPUB and Kindle. Book excerpt:

Download or read book Meetings on Atomic Energy written by and published by . This book was released on 1998 with total page 904 pages. Available in PDF, EPUB and Kindle. Book excerpt:

Download or read book Breast Health the Natural Way written by Deborah Mitchell and published by Turner Publishing Company. This book was released on 2007-07-20 with total page 155 pages. Available in PDF, EPUB and Kindle. Book excerpt: Discover the road to breast health and overall well-being Only about 10% of breast cancer is linked to heredity and genes; the majority is associated with lifestyle and environmental factors. This means that you can take control of your breast health-and work to prevent cancer and many other common breast problems. Written by two authorities in complementary medicine and women's health issues, Breast Health the Natural Way is a compassionate guide that combines mainstream and alternative medical advice, nutrition, exercise, and mind-body medicine into a simple, five-step program you can follow to ensure the health of your breasts. With reassuring understanding of women's concerns, Dr. Deborah Gordon explains: * Healthy food choices for breast health-including powerful cancer-fighting sources * Hormone therapy and how to decide if it's right for you * Exercise and meditation/visualization techniques to cut your breast cancer risk * How to perform a breast self-examination properly * How to understand and deal with breast changes during pregnancy * Other breast conditions, including cyclic fibrocystic changes, breast pain, nipple discharge, implants, breast reconstruction, mastectomy, and more. Uniquely created from a woman's perspective, Breast Health the Natural Way offers you a wellspring of insight along with the information and tools you need to ensure the health of your breasts-and the rest of your body.

Download or read book Research in Psychiatry written by L.K. George Hsu and published by Springer Science & Business Media. This book was released on 2013-11-11 with total page 486 pages. Available in PDF, EPUB and Kindle. Book excerpt: This multiauthored textbook is directed to the psychiatric resident and other professionals who are interested in the issues, strategies, and methods of psychiatric research. Although the field of psychiatry has not attained the scientific rigor and clinical sophistication of some of its sister disciplines in the medical arena, considerable progress has been made in the last decade or two, and a full understanding of the types of articles that now appear in such publications as the American Journal of Psychiatry, the Archives of General Psychi atry, and the Journal of the American Academy of Child and Adolescent Psychiatry requires a fair amount of knowledge about research design and strategy. Whereas articles in psychiatric journals 20 years ago dealt mainly with psycho dynamic topics and utilized nonexperimental observations, today their counter parts are concerned mostly with psychobiology, clinical features, diagnosis, and treatment, and employ scientific experimental designs. The trend of applying scientific methodology to research in psychiatry is increasing and undoubtedly will continue to do so in the future.

Download or read book Anticancer Research written by and published by . This book was released on 1999 with total page 1188 pages. Available in PDF, EPUB and Kindle. Book excerpt:

Download or read book International Journal of Oncology written by and published by . This book was released on 1999 with total page 630 pages. Available in PDF, EPUB and Kindle. Book excerpt:

Download or read book Education for More Synergistic Practice of Medicine and Public Health written by Mary Hager and published by . This book was released on 1999 with total page 296 pages. Available in PDF, EPUB and Kindle. Book excerpt:

Download or read book Toxicological Profile for Jet Fuels JP 4 and JP 7 written by and published by . This book was released on 1995 with total page 158 pages. Available in PDF, EPUB and Kindle. Book excerpt:

Download or read book Cancer Forum written by and published by . This book was released on 2006 with total page 474 pages. Available in PDF, EPUB and Kindle. Book excerpt:

Download or read book Annual Report written by Basel Institute for Immunology and published by . This book was released on 1998 with total page 298 pages. Available in PDF, EPUB and Kindle. Book excerpt:

Download or read book Commissioned Corps Bulletin written by United States. Public Health Service. Commissioned Corps and published by . This book was released on 1992 with total page 760 pages. Available in PDF, EPUB and Kindle. Book excerpt: