Download or read book Testing Drugs for Physical Dependence Potential and Abuse Liability written by Committee on Problems of Drug Dependence (U.S.) and published by . This book was released on 1984 with total page 172 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Download or read book Testing for Abuse Liability of Drugs in Humans written by Marian W. Fischman and published by . This book was released on 1989 with total page 420 pages. Available in PDF, EPUB and Kindle. Book excerpt: Representatives from industry, academia and government discuss issues related to testing for drug abuse liability and dependence potential. Contributors critically assess current methods for evaluating drugs in human subjects and describe both the advantages and limitations of each approach. This information permits identification of areas in which further research and development are needed.
Download or read book Testing Drugs for Physical Dependence Potential and Abuse Liability written by and published by . This book was released on 1984 with total page 153 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Download or read book Testing Drugs for Physical Dependence Potential and Abuse Liability written by Joseph V. Brady and published by . This book was released on 1984 with total page 154 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Download or read book Nonclinical Assessment of Abuse Potential for New Pharmaceuticals written by Carrie Markgraf and published by Academic Press. This book was released on 2015-07-14 with total page 321 pages. Available in PDF, EPUB and Kindle. Book excerpt: Nonclinical Assessment of Abuse Potential for New Pharmaceuticals offers a complete reference on the current international regulatory guidelines and details best practice methodology for the three standard animal models used to evaluate abuse potential: physical dependence, self-administration and drug discrimination. This book also includes chapters on alternative models and examples of when you should use these alternatives. Case histories are provided at the end of the book to show how the data generated from the animal models play a pivitol role in the submission package for a new drug. By incorporating all of this information into one book, Nonclinical Assessment of Abuse Potential for New Pharmaceuticals is your single resource for everything you need to know to understand and implement the assessment of abuse liability. Provides a consolidated overview of the complex regulatory landscape Offers best practice methodology for conducting animal studies, including selection of doses and positive control agents that will help you improve your own abuse potential studies Includes real-life examples to illustrate how nonclinical data fit into the submission strategy
Download or read book NIDA Research Monograph written by and published by . This book was released on 1976 with total page 432 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Download or read book Methods of Assessing the Reinforcing Properties of Abused Drugs written by Michael A. Bozarth and published by Springer Science & Business Media. This book was released on 2012-12-06 with total page 658 pages. Available in PDF, EPUB and Kindle. Book excerpt: Methods of Assessing the Reinforcing Properties of Abused Drugs presents a synopsis of the preclinical procedures used to assess drug reinforcement. Researchers using one technique are provided with an overview of the other available methods, and clinicians who wish to evaluate drug abuse research reports can gain the necessary background from this volume. Although emphasis is placed on the methodological aspects of assessing drug reinforcement, some of the scientific conclusions derived from using these techniques are also presented. This edited collection offers a lasting framework for interpreting the results of current experimental findings.
Download or read book Pathways of Addiction written by Institute of Medicine and published by National Academies Press. This book was released on 1996-11-01 with total page 330 pages. Available in PDF, EPUB and Kindle. Book excerpt: Drug abuse persists as one of the most costly and contentious problems on the nation's agenda. Pathways of Addiction meets the need for a clear and thoughtful national research agenda that will yield the greatest benefit from today's limited resources. The committee makes its recommendations within the public health framework and incorporates diverse fields of inquiry and a range of policy positions. It examines both the demand and supply aspects of drug abuse. Pathways of Addiction offers a fact-filled, highly readable examination of drug abuse issues in the United States, describing findings and outlining research needs in the areas of behavioral and neurobiological foundations of drug abuse. The book covers the epidemiology and etiology of drug abuse and discusses several of its most troubling health and social consequences, including HIV, violence, and harm to children. Pathways of Addiction looks at the efficacy of different prevention interventions and the many advances that have been made in treatment research in the past 20 years. The book also examines drug treatment in the criminal justice setting and the effectiveness of drug treatment under managed care. The committee advocates systematic study of the laws by which the nation attempts to control drug use and identifies the research questions most germane to public policy. Pathways of Addiction provides a strategic outline for wise investment of the nation's research resources in drug abuse. This comprehensive and accessible volume will have widespread relevanceâ€"to policymakers, researchers, research administrators, foundation decisionmakers, healthcare professionals, faculty and students, and concerned individuals.
Download or read book Urine Testing for Drugs of Abuse written by and published by . This book was released on 1986 with total page 132 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Download or read book Federal Regulation of Methadone Treatment written by Committee on Federal Regulation of Methadone Treatment and published by National Academies Press. This book was released on 1995-02-01 with total page 251 pages. Available in PDF, EPUB and Kindle. Book excerpt: For nearly three decades, methadone hydrochloride has been the primary means of treating opiate addiction. Today, about 115,000 people receive such treatment, and thousands more have benefited from it in the past. Even though methadone's effectiveness has been well established, its use remains controversial, a fact reflected by the extensive regulation of its manufacturing, labeling, distribution, and use. The Food and Drug Administration regulates the safety and effectiveness of methadone, as it does for all drugs, and the Drug Enforcement Administration regulates it as a controlled substance. However, methadone is also subjected to a unique additional tier of regulation that prescribes how and under what circumstances it may be used to treat opiate addiction. Federal Regulation of Methadone Treatment examines current Department of Health and Human Services standards for narcotic addiction treatment and the regulation of methadone treatment programs pursuant to those standards. The book includes an evaluation of the effect of federal regulations on the provision of methadone treatment services and an exploration of options for modifying the regulations to allow optimal clinical practice. The volume also includes an assessment of alternatives to the existing regulations.
Download or read book Predicting Dependence Liability of Stimulant and Depressant Drugs written by Travis Thompson and published by . This book was released on 1977 with total page 360 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Download or read book Testing for Abuse Liability of Drugs in Humans written by and published by . This book was released on 1989 with total page 0 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Download or read book Clinical Testing on Drug Abuse Liability written by Jordi Camí and published by . This book was released on 1991 with total page 143 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Download or read book Pain Management and the Opioid Epidemic written by National Academies of Sciences, Engineering, and Medicine and published by National Academies Press. This book was released on 2017-09-28 with total page 483 pages. Available in PDF, EPUB and Kindle. Book excerpt: Drug overdose, driven largely by overdose related to the use of opioids, is now the leading cause of unintentional injury death in the United States. The ongoing opioid crisis lies at the intersection of two public health challenges: reducing the burden of suffering from pain and containing the rising toll of the harms that can arise from the use of opioid medications. Chronic pain and opioid use disorder both represent complex human conditions affecting millions of Americans and causing untold disability and loss of function. In the context of the growing opioid problem, the U.S. Food and Drug Administration (FDA) launched an Opioids Action Plan in early 2016. As part of this plan, the FDA asked the National Academies of Sciences, Engineering, and Medicine to convene a committee to update the state of the science on pain research, care, and education and to identify actions the FDA and others can take to respond to the opioid epidemic, with a particular focus on informing FDA's development of a formal method for incorporating individual and societal considerations into its risk-benefit framework for opioid approval and monitoring.
Download or read book Theories on Drug Abuse written by National Institute on Drug Abuse. Division of Research and published by . This book was released on 1980 with total page 534 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Download or read book Special Issue Clinical Testing of Drug Abuse Liability written by Jordi Camí and published by . This book was released on 1991 with total page 143 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Download or read book Problems of Drug Dependence 1996 written by Louie S. Harrie and published by DIANE Publishing. This book was released on 1999-08 with total page 473 pages. Available in PDF, EPUB and Kindle. Book excerpt: Symposium presentations address: molecular biological tools in exploring behavior; drugs of abuse and the immune system; marijuana use; motivational aspects of drug abuse; excitatory amino acids in stimulant abuse and AIDS dementia; agonist efficacy, drug dependence, and medications development; drugs of abuse and gender differences; presynaptic and postsynaptic neurochemical alterations in human psychostimulant abusers; antibody and protein based therapies for drug abuse; behavioral and pharmacological interventions for pregnant substance abusers; and mechanisms of abused drugs: concordance between lab. animal and human studies.
