Download or read book Synthesis and Applications of Isotopically Labelled Compounds written by Ulrich Pleiss and published by . This book was released on 2001-03-28 with total page 736 pages. Available in PDF, EPUB and Kindle. Book excerpt: This outstanding book covers the most recent advances in the production of stable and radioactive isotopes as well as in the synthesis, analysis and applications of isotopically labelled compounds. Written by internationally renowned contributors, it provides authoritative and wide-ranging coverage of significant growth areas including: * new methodologies in the production of isotopes * novel approaches to compounds labelled with isotopes of hydrogen, carbon and other stable, long-lived and short-lived radioactive isotopes * advances in the analysis of istopically labelled compounds * recent and future applications of isotopes in pharmaceutical research and development, in pharmacological and clinical sutdies and nuclear medicine, as well as in agricultural, nutritional and environmental research * recent applications of isotopes in investigating organic and bioorganic mechanisms and pathways * safety and regulations of handling isotopes This will be an invaluable information and reference source to anyone involved in the production of isotopes, the synthesis and analysis of compounds labelled with stable, long-lived or short-lived radioactive isotopes, in drug research and development, in clinical investigations and nuclear medicine, in agricultural research and development and environmental investigations, in the elucidation of biological and chemical pathways, handling radioisotopes, laboratory design and other areas.

Download or read book Synthesis and Applications of Isotopically Labelled Compounds written by Ulrich Pleiss and published by . This book was released on 2001 with total page pages. Available in PDF, EPUB and Kindle. Book excerpt:

Download or read book Synthesis and Applications of Isotopically Labelled Compounds written by Ulrich Pleiss and published by Wiley. This book was released on 2001-03-28 with total page 736 pages. Available in PDF, EPUB and Kindle. Book excerpt: This outstanding book covers the most recent advances in the production of stable and radioactive isotopes as well as in the synthesis, analysis and applications of isotopically labelled compounds. Written by internationally renowned contributors, it provides authoritative and wide-ranging coverage of significant growth areas including: * new methodologies in the production of isotopes * novel approaches to compounds labelled with isotopes of hydrogen, carbon and other stable, long-lived and short-lived radioactive isotopes * advances in the analysis of istopically labelled compounds * recent and future applications of isotopes in pharmaceutical research and development, in pharmacological and clinical sutdies and nuclear medicine, as well as in agricultural, nutritional and environmental research * recent applications of isotopes in investigating organic and bioorganic mechanisms and pathways * safety and regulations of handling isotopes This will be an invaluable information and reference source to anyone involved in the production of isotopes, the synthesis and analysis of compounds labelled with stable, long-lived or short-lived radioactive isotopes, in drug research and development, in clinical investigations and nuclear medicine, in agricultural research and development and environmental investigations, in the elucidation of biological and chemical pathways, handling radioisotopes, laboratory design and other areas.

Download or read book 10th International Symposium on the Synthesis and Applications of Isotopes and Isotopically Labelled Compounds written by International Symposium on the Synthesis and Applications of Isotopes and Isotopically Labelled Compounds 10, 2009, Chicago, Ill and published by . This book was released on 2010 with total page 275 pages. Available in PDF, EPUB and Kindle. Book excerpt:

Download or read book Synthesis and Applications of Isotopically Labelled Compounds 1997 written by J. R. Heys and published by . This book was released on 1998-06-11 with total page 776 pages. Available in PDF, EPUB and Kindle. Book excerpt: Synthesis and Applications of Isotopically Labelled Compounds provides a wide-ranging, authoritative and comprehensive coverage of the most recent advances in the synthesis, production and applications of stable and radioactive isotopes. This volume focuses on significant growth areas including applications of isotopes in clinical research and medicine, advances in the analysis of isotopically labelled compounds, novel approaches to compounds labelled with isotopes of hydrogen, applications of isotopes in organic and bio-organic reaction mechanisms, isotopes in macro-molecules, applications of isotopes in metabolism and toxicology, production of stable isotopes and radioisotopes and applications of isotopes in pharmaceutical and agricultural research. Contributions are drawn from major research groups around the world providing an invaluable information and reference source to anyone involved in the production of isotopes, the synthesis and analysis of stable or radioactive isotopically labelled compounds, the applications of short-lived isotopes, drug metabolism and pharmacokinetics, pharmaceutical research and development, clinical research, biosynthesis, handling radioisotopes, laboratory design and other related areas.

Download or read book Synthesis and Applications of Isotopically Labelled Compounds 1991 written by E. Buncel and published by Elsevier Publishing Company. This book was released on 1992 with total page 820 pages. Available in PDF, EPUB and Kindle. Book excerpt: The Fourth International Symposium on the Synthesis and Applications of Isotopes and Isotopically Labelled Compounds attracted some 400 scientists from over 20 countries. The scientific program consisted of three plenary lectures, 97 invited and contributed talks presented in 15 sessions on diverse topics, and 85 poster presentations. This proceedings volume covers the full texts of all the contributions, providing comprehensive, state-of-the-art information of interest to readers in chemistry, pharmacology, biochemistry and the medical sciences.

Download or read book Synthesis and Applications of Isotopically Labelled Compounds written by David Hesk and published by Elsevier. This book was released on 2024-02-04 with total page 0 pages. Available in PDF, EPUB and Kindle. Book excerpt: Synthesis and Applications of Isotopically-Labelled Compounds: Recent Advances and Emerging Topics reviews recent advances in the field of tritium, carbon-14, and stable isotope compound synthesis along with their analysis.The emerging field of the development of deuterated pharmaceuticals is also discussed, along with the application of isotopically labelled compounds in drug metabolism studies.There currently is no authoritative text for this area that presents a comprehensive guide to the field for the community, as well as newcomers, interested parties or collaborators who need to be able to communicate with the labeling groups. This book will fill this gap and provide a "one-stop shop" by having a comprehensive review of recent developments This book will cover details around the analytical chemistry in depth in Chapter 9 which will tie in the with synthesis reviews in the earlier chapters 1 through 4. Chapter 3 will also include a section on a new method of stable isotope analysis. In addition, Chapters 5, 7 and will cover the analytical chemistry aspects of these specific areas.

Download or read book The Organic Chemistry of Isotopic Labelling written by James R Hanson and published by Royal Society of Chemistry. This book was released on 2019-04-05 with total page 201 pages. Available in PDF, EPUB and Kindle. Book excerpt: The chemical synthesis of isotopically labelled compounds is a pre-requisite for many chemical, biochemical and medicinal investigations. The constraints imposed by the requirements for regiospecific labelling and, in some instances, the time-scale of the synthesis often lead to quite different synthetic strategies to those that are used for the unlabelled material. Whilst there are many specialist papers, reviews and long books devoted to particular isotopes, there is no currently available short introductory book devoted to the organic chemistry of isotopic labelling. The aim of this book is to introduce research workers to a variety of methods that have been used to achieve these synthetic labelling objectives before exploring a particular method in detail. It covers a number of different isotopes and the methods that have been used to introduce them into organic compounds. Labelling methods also provide useful undergraduate teaching examples of modern synthetic reactions and their stereochemical consequences using relatively simple substrates. The book will therefore have a wider appeal than just those involved in using isotopes in research such as environmental and pharmaceutical chemists as well as organic chemists.

Download or read book Synthesis and Applications of Isotopically Labelled Compounds 1988 written by Thomas A. Baillie and published by Elsevier Publishing Company. This book was released on 1989 with total page 874 pages. Available in PDF, EPUB and Kindle. Book excerpt:

Download or read book International Symposium on the Synthesis and Applications of Isotopically Labelled Compounds 2 written by and published by . This book was released on 1985 with total page pages. Available in PDF, EPUB and Kindle. Book excerpt:

Download or read book Proceedings of the Ninth International Symposium on the Synthesis and Applications of Isotopically Labelled Compounds written by International Symposium on the Synthesis and Applications of Isotopes and Isotopically Labelled Compounds (9, 2006, Edinburgh) and published by . This book was released on 2007 with total page 641 pages. Available in PDF, EPUB and Kindle. Book excerpt:

Download or read book Synthesis and Applications of Isotopically Labelled Compounds written by and published by . This book was released on with total page pages. Available in PDF, EPUB and Kindle. Book excerpt:

Download or read book International Symposium on the Synthesis and Applications of Isotopically Labelled Compounds 3 written by and published by . This book was released on 1988 with total page pages. Available in PDF, EPUB and Kindle. Book excerpt:

Download or read book International Symposium on the Synthesis and Applications of Isotopically Labelled Compounds 4 written by and published by . This book was released on 1991 with total page pages. Available in PDF, EPUB and Kindle. Book excerpt:

Download or read book Synthesis and Applications of Isotopically Labelled Compounds Proceedings of the International Symposium Held in Innsbruck Austria on 17 21 July 1988 written by Thomas A. Baillie and published by . This book was released on 1988 with total page 861 pages. Available in PDF, EPUB and Kindle. Book excerpt: Stable isotopes (2H, 13C) are useful for studies on the metabolism of endogenous or exogenous compounds. GC/MS makes it possible to measure partial loss of 2H by exchange from polydeute-rated molecules and to detect compartmentation of precursors. Oxidoreduction can be studied by measurements of the loss of isotope from the carbon carrying the hydroxyl group. Label in the coenzyme can be corrected for by the use of mixtures of differently labelled compounds. Isotope effects can be used to study mechanisms in vitro and pathways in vivo. Labelling in vivo with 2H-substrates makes it possible to distinguish coenzyme pools. Topics discussed in this symposia include: Synthesis and Applications of Organic Compounds Labelled With Isotopic Hydrogen; Applications of Stable Isotopes and NMR Spectroscopy for In Vivo Studies; Radiation-Induced Reactions; Applications of Isotopically-Labelled Compounds in Clinical Research; Isotopes in Organic and Bio-Organic Reaction Mechanisms; New Techniques in Isotopic Analysis; Synthesis and Application of Organic Compounds Labelled With Iodine Isotopes; Synthesis of Isotopically-Labelled Compounds Via Organometallic Chemistry; Synthesis and Applications of Organic Compounds Labelled With Isotopic Carbon, Sulphur and Other Isotopes; The Use of Isotopically Labelled Compounds in Studies of Drug Metabolism, Disposition and Toxicity; Synthesis and Applications of Labelled Compounds in Positron Emission Trans-Axial Tomography; Applications of Radioactively-Labelled Compounds to In Vitro and In Vivo Research.(AW).

Download or read book Synthesis and Applications of Isotopically Labelled Compounds written by William P. Duncan and published by . This book was released on 1983 with total page 508 pages. Available in PDF, EPUB and Kindle. Book excerpt:

Download or read book Preparation of Compounds Labeled with Tritium and Carbon 14 written by Rolf Voges and published by John Wiley & Sons. This book was released on 2009-03-12 with total page 682 pages. Available in PDF, EPUB and Kindle. Book excerpt: Compounds labeled with carbon-14 and tritium are indispensable tools for research in biomedical sciences, discovery and development of pharmaceuticals and agrochemicals. Preparation of Compounds Labeled with Tritium and Carbon-14 is a comprehensive, authoritative and up-to-date discussion of the strategies, synthetic approaches, reactions techniques, and resources for the preparation of compounds labeled with either of these isotopes. A large number of examples are presented for the use of isotopic sources and building blocks in the preparation of labeled target compounds, illustrating the range of possibilities for embedding isotopic labels in selected moieties of complex structures. Topics include: Formulation of synthetic strategies for preparing labeled compounds Isotope exchange methods and synthetic alternatives for preparing tritiated compounds In-depth discussion of carbon-14 building blocks and their utility in synthesis Preparation of enantiomerically pure isotopically labeled compounds Applications of biotransformations Preparation of Compounds Labeled with Tritium and Carbon-14 is an essential guide to the specialist strategies and tactics used by chemists to prepare compounds tagged with theradioactive atoms carbon-14 and tritium.