Download or read book Surgical Adhesives Sealants written by David H. Sierra and published by CRC Press. This book was released on 2020-03-06 with total page 268 pages. Available in PDF, EPUB and Kindle. Book excerpt: Surgical tissue adhesives are an ancient idea, going back to the beginnings of recorded history. The concept of adhering, rather than suturing, packing, or stapling planes of tissue is attractive, in that it is fast-acting and assures complete closure. Numerous technologies have been tried; some with limited success, others outright failures. In short, the perfect adhesive does not exist. Limitations occur in a number of areas: strength, toxicity, degradation, and safety. It is also important to keep in mind that "one size fits all" does not apply to adhesives in surgical applications any more than it does in day-to-day application. As one would not use paper glue to seal a bathtub, one would presumably not apply an adhesive onto tendons, which is suitable for sealing corneas. The properties required of an adhesive for each indication are quite different. Over the last twenty-five years, advances have been made in a wide range of technologies targeting some embodiment of a practical and safe adhesive. Foremost and successful among these are cyanoacrylates, marine adhesive proteins, and fibrin-based sealants. Another promising adhesive technology is laser solders, a mixture of polypeptides and proteoglycans, which integrates with the repair site when laser energy is applied. In light of these advances in the field, the Symposium for Surgical Tissue Adhesives was organized and held at the Atlanta Hyatt from October 8-10, 1993. The goal was to bring together these far-flung technologies in a comprehensive and cohesive manner. Presentations by investigators from around the world described the history of adhesives in medicine, current technologies, laboratory characterizations, and application developments, as well as regulatory aspects and clinical applications. We felt that as many viewpoints as possible, however conflicting, were important to present in order to give the most complete picture of the state of the art of surgical adhesives.
Download or read book Tissue Adhesives in Clinical Medicine written by James V. Quinn and published by PMPH-USA. This book was released on 2005 with total page 196 pages. Available in PDF, EPUB and Kindle. Book excerpt: This second edition has expanded the scope and depth of the original text and includes all types of tissue adhesives, their proper indications and their uses. It also adds a final chapter on regulatory issues that contains FDA scientist George Mattamal's perspectives on all adhesives now used clinically or being evaluated by the FDA. The contributors address topics such as the history and background of tissue adhesives, clinical approaches to the use of cyanoacrylate tissue adhesives, protein polymers, and bone cements. The CD-ROM accompanying the book features video demonstrations of techniques. Annotation : 2005 Book News, Inc., Portland, OR (booknews.com).
Download or read book SURGICAL ADHESIVES and SEALANTS written by Taylor & Francis Group and published by . This book was released on 2020-12-18 with total page pages. Available in PDF, EPUB and Kindle. Book excerpt:
Download or read book Joining and Assembly of Medical Materials and Devices written by Y N Zhou and published by Elsevier. This book was released on 2013-05-31 with total page 583 pages. Available in PDF, EPUB and Kindle. Book excerpt: As medical devices become more intricate, with an increasing number of components made from a wide range of materials, it is important that they meet stringent requirements to ensure that they are safe to be implanted and will not be rejected by the human body. Joining and assembly of medical materials and devices provides a comprehensive overview of joining techniques for a range of medical materials and applications.Part one provides an introduction to medical devices and joining methods with further specific chapters on microwelding methods in medical components and the effects of sterilization on medical materials and welded devices. Part two focuses on medical metals and includes chapters on the joining of shape memory alloys, platinum (Pt) alloys and stainless steel wires for implantable medical devices and evaluating the corrosion performance of metal medical device welds. Part three moves on to highlight the joining and assembly of medical plastics and discusses techniques including ultrasonic welding, transmission laser welding and radio frequency (RF)/dielectric welding. Finally, part four discusses the joining and assembly of biomaterial and tissue implants including metal-ceramic joining techniques for orthopaedic applications and tissue adhesives and sealants for surgical applications.Joining and assembly of medical materials and devices is a technical guide for engineers and researchers within the medical industry, professionals requiring an understanding of joining and assembly techniques in a medical setting, and academics interested in this field. Introduces joining methods in medical applications including microwelding and considers the effects of sterilization on the resulting joints and devices Considers the joining, assembly and corrosion performance of medical metals including shape memory alloys, platinum alloys and stainless steel wires Considers the joining and assembly of medical plastics including multiple welding methods, bonding strategies and adhesives
Download or read book Surgical Adhesives Sealants written by David H. Sierra and published by CRC Press. This book was released on 2020-03-06 with total page 276 pages. Available in PDF, EPUB and Kindle. Book excerpt: Surgical tissue adhesives are an ancient idea, going back to the beginnings of recorded history. The concept of adhering, rather than suturing, packing, or stapling planes of tissue is attractive, in that it is fast-acting and assures complete closure. Numerous technologies have been tried; some with limited success, others outright failures. In short, the perfect adhesive does not exist. Limitations occur in a number of areas: strength, toxicity, degradation, and safety. It is also important to keep in mind that "one size fits all" does not apply to adhesives in surgical applications any more than it does in day-to-day application. As one would not use paper glue to seal a bathtub, one would presumably not apply an adhesive onto tendons, which is suitable for sealing corneas. The properties required of an adhesive for each indication are quite different. Over the last twenty-five years, advances have been made in a wide range of technologies targeting some embodiment of a practical and safe adhesive. Foremost and successful among these are cyanoacrylates, marine adhesive proteins, and fibrin-based sealants. Another promising adhesive technology is laser solders, a mixture of polypeptides and proteoglycans, which integrates with the repair site when laser energy is applied. In light of these advances in the field, the Symposium for Surgical Tissue Adhesives was organized and held at the Atlanta Hyatt from October 8-10, 1993. The goal was to bring together these far-flung technologies in a comprehensive and cohesive manner. Presentations by investigators from around the world described the history of adhesives in medicine, current technologies, laboratory characterizations, and application developments, as well as regulatory aspects and clinical applications. We felt that as many viewpoints as possible, however conflicting, were important to present in order to give the most complete picture of the state of the art of surgical adhesives.
Download or read book Green Adhesives written by Inamuddin and published by John Wiley & Sons. This book was released on 2020-06-03 with total page 304 pages. Available in PDF, EPUB and Kindle. Book excerpt: Green Adhesives: Preparation, Properties and Applications deals with the fabrication methods, characterization, and applications of green adhesives. It also includes the collective properties of waterborne, bio, and wound-healing green adhesives. Exclusive attention is devoted to discussing the applications of green adhesives in biomedical coatings, food, and industrial applications.
Download or read book Biomaterials for Surgical Operation written by Shuko Suzuki and published by Springer Science & Business Media. This book was released on 2011-12-21 with total page 218 pages. Available in PDF, EPUB and Kindle. Book excerpt: Biomaterials for Surgical Operation offers a review of the latest advances made in developing bioabsorbable devices for surgical operations which include surgical adhesives (sealants), barriers for the prevention of tissue adhesion, polymers for fractured bone fixation, growth factors for the promotion of wound healing, and sutures. Over the years, many descriptions of biomaterials have appeared in academic journals and books, but most of them have been devoted to limited clinical areas. This is in marked contrast with this volume which covers a wide range of bioabsorbable devices used in surgery from a practical point of view. The currently applied polymeric devices are critical in surgery, but all involve serious problems due to their poor performance. For instance, fibrin glue, the most widely used surgical sealant, can produce only a weak gel with low adhesive strength to tissues, accentuating the limited effectiveness of current treatment options. Likewise, the currently available barrier membranes cannot fully prevent tissue adhesion at the acceptable level and are, moreover, not easy to handle with endoscopes due to their poor mechanical properties. Biomaterials for Surgical Operation is aimed at those who are interested in expanding their knowledge of how the problems associated with the currently used devices for surgical operation can be solved. It primarily focuses on the absorbable biomaterials which are the main components of these medical devices.
Download or read book Tissue Adhesives in Surgery written by Teruo Matsumoto and published by . This book was released on 1972 with total page 536 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Download or read book Cardiac Surgery written by Shahzad G. Raja and published by Springer Nature. This book was released on 2020-02-11 with total page 1089 pages. Available in PDF, EPUB and Kindle. Book excerpt: This textbook provides a succinct overview of cardiac surgery, with key concepts being emphasized throughout. An abundance of illustrations, intra-operative photographs, tables as well as information boxes, aids the reader to visualise, grasp and retain difficult concepts. The inclusion of evidence-based approaches to the management of a range of cardiac surgical conditions equips the reader with an understanding of how to overcome a variety of potentially tough clinical challenges. Concise Cardiac Surgery: A Complete Guide comprehensively covers a range of techniques used in cardiac surgery. It is therefore, an ideal resource for the trainee and practising cardiac surgeon seeking a practically focused text detailing how to apply the latest techniques and evidence-based approaches in their day-to-day practice.
Download or read book Tissue Adhesives in Wound Care written by James V. Quinn and published by B.C. Decker. This book was released on 1998 with total page 0 pages. Available in PDF, EPUB and Kindle. Book excerpt: Next to the common cold, traumatic wounds are the commonest reason people seek medical care. There are approximately 12 million traumatic wounds and 90 million surgical procedures each year in the United States. While tissue adhesives will not and should not replace all sutures, their availablilty will change the practice of physicans and surgeons.
Download or read book Advanced Wound Repair Therapies written by David Farrar and published by Elsevier. This book was released on 2011-06-21 with total page 672 pages. Available in PDF, EPUB and Kindle. Book excerpt: Wound repair is an important and growing sector of the medical industry with increasingly sophisticated biomaterials and strategies being developed to treat wounds. Advanced wound repair therapies provides readers with up-to-date information on current and emerging biomaterials and advanced therapies concerned with healing surgical and chronic wounds.Part one provides an introduction to chronic wounds, with chapters covering dysfunctional wound healing, scarring and scarless wound healing and monitoring of wounds. Part two covers biomaterial therapies for chronic wounds, including chapters on functional requirements of wound repair biomaterials, polymeric materials for wound dressings and interfacial phenomena in wound healing. In part three, molecular therapies for chronic wounds are discussed, with chapters on topics such as drug delivery, molecular and gene therapies and antimicrobial dressings. Part four focuses on biologically-derived and cell-based therapies for chronic wounds, including engineered tissues, biologically-derived scaffolds and stem cell therapies for wound repair. Finally, part five covers physical stimulation therapies for chronic wounds, including electrical stimulation, negative pressure therapy and mechanical debriding devices.With its distinguished editor and international team of contributors, Advanced wound repair therapies is an essential reference for researchers and materials scientists in the wound repair industry, as well as clinicians and those with an academic research interest in the subject. Provides readers with up-to-date information on current and emerging biomaterials and advanced therapies concerned with healing surgical and chronic wounds Chapters include the role of micro-organisms and biofilms in dysfunctional wound healing, tissue-biomaterial interaction and electrical stimulation for wound healing Covers biologically-derived and cell-based therapies for chronic wounds, including engineered tissues, biologically-derived scaffolds and stem cell therapies for wound repair
Download or read book Bioadhesion and Biomimetics written by Havazelet Bianco-Peled and published by CRC Press. This book was released on 2015-03-02 with total page 310 pages. Available in PDF, EPUB and Kindle. Book excerpt: Bioadhesion is often defined as the state in which two materials, at least one of which is biological in nature, are held together for extended periods of time by interfacial forces. It is an area of active multidisciplinary research, where engineers, scientists-including chemists, physicists, biologists, and medical experts-materials' producers, a
Download or read book Wound Closure Biomaterials and Devices written by Chih-Chang Chu and published by CRC Press. This book was released on 2018-05-04 with total page 416 pages. Available in PDF, EPUB and Kindle. Book excerpt: "Virtually every wound, whether surgical or traumatic, needs to be closed to promote wound healing and prevent infection. Increasingly sophisticated and effective materials for the crucial surgical treatment of wound closure are being developed continuously. Keep up with the most recent research progress and future trends in this complex and rapidly changing field with Wound Closure Biomaterial and Devices. This state-of-the-art book provides detailed information and critical discussions on: ï
Download or read book Engineering a Highly Adhesive and Hemostatic Sealant for Soft Tissues written by Sevana Baghdasarian and published by . This book was released on 2020 with total page 75 pages. Available in PDF, EPUB and Kindle. Book excerpt: The existing surgical adhesives and sealants lack strong adherence to the biological tissues in the wet environment. In addition, demonstrating both inherently high adhesion and hemostatic functionalities in one product, is a scarce characteristic of the developed biomaterials. Moreover, to eliminate the physical and mechanical mismatches with native tissues, high tuning ability is desirable but limited in the current products. As a result, the current solutions fail to either close the wound, or maintain a sufficient sealing ability during wound healing. In this work, a novel and efficient synthetic technique was successfully developed to chemically conjugate catechol motifs to the gelatin backbone. The resulting gelatin-catechol compound was then chemically functionalized with methacryloyl groups to form a highly adhesive and photocrosslinkable sealant, named gelatin methacryloyl-catechol (GelMAC). A two-step crosslinking approach was employed to form the double-networked, and highly tunable GelMAC hydrogel system. First, different concentrations of Fe3+ ions (0, 1, 2.5, 5 and 10 M) were introduced to the 20 %(w/v) GelMAC prepolymer solution. This step was followed by a second crosslinking mechanism utilizing visible light photopolymerization. GelMAC hydrogel with 2.5 M Fe3+ ion concentration (GelMAC-Fe) was found to have lower elastic and compressive moduli but demonstrated comparable extensibility to Gelatin-methacryloyl (GelMA) hydrogel incorporating the same Fe3+ ion concentration (GelMA-Fe). Moreover, the wound closure test with porcine skin showed a 1.5-fold higher adhesive strength for GelMAC-Fe compared to GelMA-Fe hydrogels. To study the hemostatic efficacy of GelMAC-Fe hydrogel, the time lapse of blood coagulation across experimental groups was studied in vitro. While the negative control group (untreated blood) formed a blood clot after 16 min, GelMAC hydrogels decreased the clotting time significantly to 9 min. These results were also in close agreement with those obtained for the commercially available hemostatic material, SURGICEL . Finally, the results of the in vivo liver bleeding model showed that GelMAC-Fe hydrogel was able to rapidly crosslink the incision site and stop the bleeding faster compared to other hydrogels. GelMAC-Fe hydrogel exhibited superior adhesion strength while offering significant hemostatic ability owing to the presence of ferric ions (Fe3+) and the dopamine molecule. This novel, highly biocompatible, tunable, adhesive, and hemostatic sealant can therefore be utilized as an effective solution for controlling bleeding and sealing of soft internal organs such as the lung, heart and blood vessels.
Download or read book Tissue Glues in Cosmetic Surgery written by Renato Saltz and published by . This book was released on 2004 with total page 232 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Download or read book Handbook of Adhesion Technology written by Lucas F. M. da Silva and published by Springer. This book was released on 2011-08-10 with total page 1554 pages. Available in PDF, EPUB and Kindle. Book excerpt: Adhesives have been used for thousands of years, but until 100 years ago, the vast majority was from natural products such as bones, skins, fish, milk, and plants. Since about 1900, adhesives based on synthetic polymers have been introduced, and today, there are many industrial uses of adhesives and sealants. It is difficult to imagine a product—in the home, in industry, in transportation, or anywhere else for that matter—that does not use adhesives or sealants in some manner. The Handbook of Adhesion Technology is intended to be the definitive reference in the field of adhesion. Essential information is provided for all those concerned with the adhesion phenomenon. Adhesion is a phenomenon of interest in diverse scientific disciplines and of importance in a wide range of technologies. Therefore, this handbook includes the background science (physics, chemistry and materials science), engineering aspects of adhesion and industry specific applications. It is arranged in a user-friendly format with ten main sections: theory of adhesion, surface treatments, adhesive and sealant materials, testing of adhesive properties, joint design, durability, manufacture, quality control, applications and emerging areas. Each section contains about five chapters written by internationally renowned authors who are authorities in their fields. This book is intended to be a reference for people needing a quick, but authoritative, description of topics in the field of adhesion and the practical use of adhesives and sealants. Scientists and engineers of many different backgrounds who need to have an understanding of various aspects of adhesion technology will find it highly valuable. These will include those working in research or design, as well as others involved with marketing services. Graduate students in materials, processes and manufacturing will also want to consult it.
Download or read book Stem Cell and Tissue Engineering written by Song Li and published by World Scientific. This book was released on 2011 with total page 473 pages. Available in PDF, EPUB and Kindle. Book excerpt: Tissue engineering integrates knowledge and tools from biological sciences and engineering for tissue regeneration. A challenge for tissue engineering is to identify appropriate cell sources. The recent advancement of stem cell biology provides enormous opportunities to engineer stem cells for tissue engineering. The impact of stem cell technology on tissue engineering will be revolutionary. This book covers state-of-the-art knowledge on the potential of stem cells for the regeneration of a wide range of tissues and organs and the technologies for studying and engineering stem cells. It serves as a valuable reference book for researchers and students.