Download or read book SUMO Protocols written by Helle Ulrich and published by Humana Press. This book was released on 2008-10-23 with total page 0 pages. Available in PDF, EPUB and Kindle. Book excerpt: Post-translational protein modifications by members of the ubiquitin family are widely recognized as important regulatory control systems for a variety of biological pathways. Their influence on eukaryotic cellular metabolism is comparable to that of other modifi- tions such as phosphorylation, acetylation and methylation. The small ubiquitin-related modifier SUMO uses a conjugation and de-conjugation system closely related to that of ubiquitin itself; yet, the functions of the SUMO system are highly diverse and largely independent of the ubiquitin system. SUMO modification controls the activity of tr- scription factors and can influence protein stability, but it also contributes to nucleo-cy- plasmic transport, chromosome segregation and DNA damage repair. As a consequence, the SUMO system pervades virtually all areas of basic molecular and cell biology, and scientists from different backgrounds, including medical researchers, are likely to enco- ter SUMO in the course of their studies. This volume, SUMO Protocols, therefore aims at presenting a collection of methods relevant to SUMO research in order to make these tools available to biochemists, molecular and cell biologists as well as research-oriented clinicians not yet familiar with the system. In contrast to the ubiquitin system, which has been the subject of several reviews and methods collections, no practical compendium entirely devoted to SUMO has been p- lished.
Download or read book Ubiquitin Proteasome Protocols written by Cam Patterson and published by Springer Science & Business Media. This book was released on 2008-02-04 with total page 376 pages. Available in PDF, EPUB and Kindle. Book excerpt: A collection of cutting-edge techniques for studying ubiquitin-dependent protein degradation via the proteasome. The topics covered range broadly from basic biochemistry to cellular assays to discovery techniques using mass spectrometric analysis. These biochemical and cellular methods are necessary to explore the ubiquitin-proteasome system and ubiquitin-proteasome-dependent functions. State-of-the-art and user-friendly, Ubiquitin-Proteasome Protocols offers novice and experienced bench scientists alike a thorough compendium of readily reproducible techniques that will accelerate discovery, enhance productivity, and permit manipulation of the system for varied research purposes.
Download or read book Plant Proteostasis written by L. Maria Lois and published by Springer Nature. This book was released on 2022-11-22 with total page 408 pages. Available in PDF, EPUB and Kindle. Book excerpt: This second edition compiles state-of-art protocols to study the molecular mechanisms that determine proteome composition and contribute to maintaining protein homeostasis. Chapters describe methods that range from the in vitro analysis of enzyme cascades to real-time in vivo studies. Written in the successful Methods in Molecular Biology series format, chapters include introductions to their respective topics, lists of the necessary materials and reagents, step-by-step, readily reproducible protocols, and notes on troubleshooting and avoiding known pitfalls. Authoritative and cutting-edge, Plant Proteostasis: Methods and Protocols, Second Edition aims to be a useful practical guide to researches to help further their study in this field.
Download or read book Formal Methods Foundations and Applications written by Sérgio Campos and published by Springer Nature. This book was released on 2021-11-25 with total page 149 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book constitutes the refereed proceedings of the 24rd Brazilian Symposium on Formal Methods, SBMF 2021, which was held in December 2021. Due to COVID 19-pandemic it took place virtually. The 8 regular papers presented in this book were carefully reviewed and selected from 15 submissions. The papers detail the development, dissemination, and use of formal methods for the construction of high-quality computational systems, aiming to promote opportunities for researchers and practitioners with an interest in formal methods to discuss the recent advances in this area
Download or read book Methods in Animal Proteomics written by Philip Whitfield and published by John Wiley & Sons. This book was released on 2011-09-13 with total page 464 pages. Available in PDF, EPUB and Kindle. Book excerpt: The study of proteomics provides researchers with a better understanding of disease and physiological processes in animals. Methods in Animal Proteomics will provide animal scientists and veterinarians currently researching these topics in domestic animals a firm foundation in the basics of proteomics methodology, while also reviewing important advances that will be of interest to established researchers in the field. Chapters will provide practical information on a range of topics including protein identification and separation, bioinformatics, and applications to disease and reproduction research. This text will be written by leading international proteomics experts and essential for researchers in the fields of animal biology and veterinary medicine.
Download or read book Pattern Recognition in Bioinformatics written by Madhu Chetty and published by Springer Science & Business Media. This book was released on 2008-09-29 with total page 488 pages. Available in PDF, EPUB and Kindle. Book excerpt: In the post-genomic era, a holistic understanding of biological systems and p- cesses,inalltheircomplexity,is criticalincomprehendingnature’schoreography of life. As a result, bioinformatics involving its two main disciplines, namely, the life sciences and the computational sciences, is fast becoming a very promising multidisciplinary research ?eld. With the ever-increasing application of lar- scalehigh-throughputtechnologies,suchasgeneorproteinmicroarraysandmass spectrometry methods, the enormous body of information is growing rapidly. Bioinformaticians are posed with a large number of di?cult problems to solve, arising not only due to the complexities in acquiring the molecular infor- tion but also due to the size and nature of the generated data sets and/or the limitations of the algorithms required for analyzing these data. Although the ?eld of bioinformatics is still in its embryonic stage, the recent advancements in computational and information-theoretic techniques are enabling us to c- ductvariousinsilicotestingandscreeningofmanylab-basedexperimentsbefore these are actually performed in vitro or in vivo. These in silico investigations are providing new insights for interpretation and establishing a new direction for a deeper understanding. Among the various advanced computational methods currently being applied to such studies, the pattern recognition techniques are mostly found to be at the core of the whole discovery process for apprehending the underlying biological knowledge. Thus, we can safely surmise that the - going bioinformatics revolution may, in future, inevitably play a major role in many aspects of medical practice and/or the discipline of life sciences.
Download or read book Current Protocols in Nucleic Acid Chemistry written by Serge L. Beaucage and published by Current Protocols. This book was released on 2000 with total page pages. Available in PDF, EPUB and Kindle. Book excerpt: Good methods must be reliable, well-tested, and honed to minimize the time and expense required to achieve the desired results. CPNC provides a continuously growing and evolving set of protocols that allows researchers to benefit from the experience of other researchers around the world. The core manual provides a comprehensive set of protocols that have been compiled, revised, and streamlined over the last 6 years. Quarterly updates provide new protocols in emerging areas of research as well as continued advances and new applications for fundamental methods. The book is designed to grow and change with the field of nucleic acid chemistry. Fundamental nucleoside chemistry methods include sugar-base condensation, phosphorylation, and nucleoside protection. Methods for oligonucleotide synthesis include H-phosphonate and phosphoramidite approaches, solid-phase and solution-phase synthesis, large-scale synthesis, synthesis for modified and unmodified oligonucleotides, conjugation of oligonucleotides, synthesis without base protection, and synthesis on microarrays. More specialized synthetic methods include synthesis of biologically active nucleosides and prodrugs. Purification and characterization methods are detailed. Advanced methods include biophysical analysis, combinatorial methods, and nanotechnology. Each protocol includes rationale for choosing appropriate methods, step-by-step procedures, complete recipes, anticipated results, characterization data, and troubleshooting, as well as background and recommended reading. The level of procedural detail is far beyond that found in the research literature, and tips and comments from authors are geared towards ensuring reliable duplication in the laboratory.
Download or read book Algorithms and Architectures for Parallel Processing written by Anu G. Bourgeois and published by Springer Science & Business Media. This book was released on 2008-05-29 with total page 331 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book constitutes the refereed proceedings of the 8th International Conference on Algorithms and Architectures for Parallel Processing, ICA3PP 2008, held in Agia Napa, Cyprus, in June 2008. The 31 revised full papers presented together with 1 keynote talk and 1 tutorial were carefully reviewed and selected from 88 submissions. The papers are organized in topical sections on scheduling and load balancing, interconnection networks, parallel algorithms, distributed systems, parallelization tools, grid computing, and software systems.
Download or read book Specific Sports Related Injuries written by Sérgio Rocha Piedade and published by Springer Nature. This book was released on 2021-05-12 with total page 544 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book offers a comprehensive and detailed overview of specific sports-related injuries and a valuable guide for decision-making to establish the best strategies to prevent and manage such injuries. As a thorough understanding of each sports modality plays a key role, both in injury prevention and management, a dedicated chapter is devoted to each sports discipline. An international panel of authors examines all most popular individual and team sports – including athletics, swimming, combat sports, cycling, tennis, American football, baseball, basketball, soccer and volleyball, just to mention a few. Three additional chapters present special aspects related to sports injuries: mental health concerns in athletes, radiological assessment and patient reported-outcomes tailored to sports medicine. All chapters share a consistent format, starting with a brief presentation of the sport and its history, and then discussing its dynamics, physical demands on the athlete, common sports-related injuries, biomechanics of injuries, first aid on the field, and injury prevention. This book offers valuable resource to orthopaedists, sports physicians as well as physiotherapists practicing in the field of sports-related injuries.
Download or read book Quality Reliability Security and Robustness in Heterogeneous Systems written by Lei Wang and published by Springer. This book was released on 2018-03-28 with total page 265 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book constitutes the refereed post-conference proceedings of the 13th International Conference on Quality, Reliability, Security and Robustness in Heterogeneous Networks, QShine 2017, held in Dalian, China, in December 2017. The 25 revised full papers were carefully reviewed and selected from 43 submissions. The papers are organized thematically in tracks, starting with mobile and wireless networks, quality and reliability, wireless networking algorithms and protocols, and smart applications.
Download or read book Advances in Intelligent Computing and Communication written by Mihir Narayan Mohanty and published by Springer Nature. This book was released on 2020-01-13 with total page 563 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book features high-quality research papers presented at the 2nd International Conference on Intelligent Computing and Advances in Communication (ICAC 2019), held at Siksha ‘O’ Anusandhan Deemed to be University, Bhubaneswar, Odisha, India, in November 2019. Covering a wide variety of topics, including management of clean and smart energy systems and environmental challenges, it is a valuable resource for researchers and practicing engineers working in various fields of renewable energy generation, and clean and smart energy management.
Download or read book Protein Chromatography written by Sinéad T Loughran and published by Springer Nature. This book was released on 2023-10-01 with total page 495 pages. Available in PDF, EPUB and Kindle. Book excerpt: This third edition expands on the previous editions with updated and new chapters on protein chromatography. Chapters detail protein stability and storage, avoiding proteolysis, protein quantitation methods, generation and purification of recombinant proteins, recombinant antibody production, and the tagging of proteins. Written in the format of the highly successful Methods in Molecular Biology series, each chapter includes an introduction to the topic, lists necessary materials and reagents, includes tips on troubleshooting and known pitfalls, and step-by-step, readily reproducible protocols. Authoritative and cutting-edge, Protein Chromatography: Methods and Protocols, Third Edition aims to provide commonly used methods and new approaches to help both new researchers and experts expand their knowledge.
Download or read book The Complementarity Between the Nagoya Protocol and Human Rights written by Xiaoou Zheng and published by Springer Nature. This book was released on 2023-08-15 with total page 187 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book studies the questions of how and to what extent the Nagoya Protocol on Access and Benefit-Sharing (ABS) can be interpreted and implemented in light of international human rights law, with a sharpened focus on Indigenous Peoples and local communities. The complementarity thesis is built upon the understanding that ABS and human rights should not and cannot be isolated from one another in order to achieve their respective objectives. A mutually supportive approach to these two bodies of international law is articulated throughout the chapters, covering a wide range of international treaties and ‘soft’ instruments, as well as the practices of the United Nations, international treaty bodies, courts, other international organizations and sometimes NGOs. Legal researchers, legislators and policymakers, human rights practitioners and indeed anyone interested in the development of a more coherent and integrated system of international ABS framework will find this book helpful, with its succinct coverage of current ABS and human rights laws and practices, their pragmatic implications and possible ways of integration forward.
Download or read book Design and Evaluation of Ad Hoc Routing Protocol written by Martine Wahl and published by John Wiley & Sons. This book was released on 2024-10-04 with total page 276 pages. Available in PDF, EPUB and Kindle. Book excerpt: Design and Evaluation of Ad Hoc Routing Protocol examines ad hoc communications between vehicles in a road environment. In this context, the book questions the sustainability of communications-dependent driver assistance services in areas where no communications infrastructure is operational. Starting with an ad hoc routing protocol proposed by the authors, this book presents a methodology from its design to its evaluation. It presents the functional requirements-based design approach and offers analyses to help us understand how the protocol functions, its properties and its performance in relation to target applications. This book is primarily aimed at beginners in the fields of protocol engineering, ad hoc networks or intelligent transport systems, but also provides specialists with an original perspective on the scientific literature in these fields. In particular, it offers concrete tools to help them develop their own methods for designing and evaluating communications protocols.
Download or read book Enzymes Advances in Research and Application 2012 Edition written by and published by ScholarlyEditions. This book was released on 2012-12-26 with total page 814 pages. Available in PDF, EPUB and Kindle. Book excerpt: Enzymes—Advances in Research and Application: 2012 Edition is a ScholarlyEditions™ eBook that delivers timely, authoritative, and comprehensive information about Enzymes. The editors have built Enzymes—Advances in Research and Application: 2012 Edition on the vast information databases of ScholarlyNews.™ You can expect the information about Enzymes in this eBook to be deeper than what you can access anywhere else, as well as consistently reliable, authoritative, informed, and relevant. The content of Enzymes—Advances in Research and Application: 2012 Edition has been produced by the world’s leading scientists, engineers, analysts, research institutions, and companies. All of the content is from peer-reviewed sources, and all of it is written, assembled, and edited by the editors at ScholarlyEditions™ and available exclusively from us. You now have a source you can cite with authority, confidence, and credibility. More information is available at http://www.ScholarlyEditions.com/.
Download or read book Smart Systems Innovations in Computing written by Arun K. Somani and published by Springer Nature. This book was released on with total page 808 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Download or read book Advances in Communication Networking written by Thomas Bauschert and published by Springer. This book was released on 2013-08-28 with total page 332 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book constitutes the refereed proceedings of the 19th EUNICE/IFIP WG 6.2, 6.6 workshop on Advances in Communication Networking, EUNICE 2013, held in Chemnitz, Germany, in August 2013. The 23 oral papers demonstrated together with 9 poster presentations were carefully reviewed and selected from 40 submissions. The papers are organized in topical sections on network modeling and design, traffic analysis, network and traffic management, services over mobile networks, monitoring and measurement, security concepts, application of ICT in smart grid and smart home environments, data dissemination in ad-hoc and sensor networks, and services and applications.
