Download or read book Studies in quinone methide chemistry written by Ashot Merijan and published by . This book was released on 1962 with total page 170 pages. Available in PDF, EPUB and Kindle. Book excerpt:

Download or read book Quinone Methides written by S. E. Rokita and published by John Wiley & Sons. This book was released on 2009-02-17 with total page 456 pages. Available in PDF, EPUB and Kindle. Book excerpt: Multidisciplinary perspectives and approaches to quinone methides research The Wiley Series on Reactive Intermediates in Chemistry and Biology investigates reactive intermediates from the broadest possible range of disciplines. The contributions in each volume offer readers fresh insights into the latest findings, emerging applications, and ongoing research in the field from a diverse perspective. This inaugural volume in the series, Quinone Methides, represents the first book devoted to this fascinating and useful intermediate. The authors of this work reflect the many disciplines and approaches to quinone methides research. The volume therefore covers a broad range of topics, including theoretical treatments, generation and detection of intermediates, characterization and applications in chemistry and biochemistry, and biological reactivity. Among the chapters are: Photochemical generation and characterization of quinone methides Quinone methide stabilization by metal complexation Self-immolative dendrimers based on quinone methides Characterization of quinone methides by spectral global fitting and 13C labeling Formation and reactions of xenobiotic quinone methides in biology Quinone methides in lignification With this collection of topics, readers already familiar with quinone methides have the opportunity to advance their own research by discovering new inspiration and opportunities in allied areas. Moreover, the range of topics and perspectives covered make this volume accessible to readers with a broad range of interests, including organic and physical chemistry, biochemistry, biotechnology, and pharmaceutics.

Download or read book Studies on the Novel Condensation Reactions of Photochemically Generated O quinone Methide written by Tom Livinghouse and published by . This book was released on 1977 with total page 168 pages. Available in PDF, EPUB and Kindle. Book excerpt:

Download or read book Quinone Methides written by Mariia Vladimirovna Sutton and published by . This book was released on 2019 with total page 54 pages. Available in PDF, EPUB and Kindle. Book excerpt: Efficient generation of quinone methides (QMs) from quinone methide precursors (QMPs) under mild conditions, such as reagent free UV-light irradiation, and exceptional reactivity of QMs towards nucleophiles and, in case of o-QMs, towards dienophiles have attracted a lot of attention to these compounds in computation, chemical, biological and engineering spheres. Our research group has demonstrated successful application of o-napthoquinone methide precursors (o-NQMPs) as photolabile protecting groups (PPGs) and linkers, that can be employed in the design of multifunctional surfaces, used as PPGs for biological molecules that carry different functional groups and as a linker for peptide and protein reversible modification. o-QMs and p-QMs demonstrate different chemical properties and different reactivity. However, to the best of our knowledge, the molecules containing competing o-NQM and p-QM moieties, have not been studied. Thus, the major goal of the first project was to develop and synthesize novel QMPs with ability to generate o-NQM and p-QM under light irradiation. Physical properties, chemical properties, such as ability to react with nucleophiles and undergo inter- and intra-molecular Diels-Alder reaction, as well as kinetic behavior of new QM-system have been studied. We were also interested in investigating the ability of o-NQMPs decorated with thiol moieties to form "smart" polymers, that could be generated upon UV-light irradiation. The photo-induced degradation of the polymers could be achieved on demand upon light irradiation in the presence of vinyl ethers. Unfortunately, light-induced polymerization of the synthesized monomers resulted in exclusive formation of oligomers. Another project has been focused on the development of a novel photocleavable analog of calcium-selective chelating ligand, which was based on the combination of properties of photolabile 3-(hydroxymethyl)-2-naphthol core and high calcium affinity of 1,2-bis(o-aminophenoxy)ethane-N, N, N', N'-tetraacetic acid (BAPTA). Finally, we have worked towards the design of a new fluorogenic PPG that could also serve as an intracellular pH indicator. 9H-xanthene-1,8,9-triol derivatives can be considered as photoactivatable fluorophores and fluorogenic PPGs, as 9H-xanthen-1,8,9-triols are expected to generate relatively stable quinone methide upon UV-light irradiation. Due to its structural similarity with fluorescein derivatives, we expected 8-hydroxy-1H-xanthen-1-one to be highly fluorescent. However, attempted synthesis resulted in the formation of a different unexpected product.

Download or read book Synthesis and Studies of a Quinone Methide Model for the Anthracycline Antitumor Antibiotics written by Catherine Woytowicz and published by . This book was released on 1997 with total page 368 pages. Available in PDF, EPUB and Kindle. Book excerpt:

Download or read book Studies on the Pro oxidant Chemistry of Flavonoids written by Hanem Mohamed Awad and published by . This book was released on 2002* with total page 133 pages. Available in PDF, EPUB and Kindle. Book excerpt:

Download or read book The Chemistry of the Quinonoid Compounds written by Saul Patai and published by . This book was released on 1988 with total page 904 pages. Available in PDF, EPUB and Kindle. Book excerpt:

Download or read book Part I Studies Directed Towards Oxidative Phenolic Coupling Via Photochemically Induced Electron Transfer Reactions Part II The Intramolecular Trapping of Thermally Generated O quinone Methides written by Gail Carolyn Shelly and published by . This book was released on 1979 with total page 444 pages. Available in PDF, EPUB and Kindle. Book excerpt:

Download or read book Studies in Natural Products Chemistry written by Atta-ur Rahman and published by Elsevier. This book was released on 1998-12-03 with total page 1365 pages. Available in PDF, EPUB and Kindle. Book excerpt: Natural Products Chemistry continues to grow at an increasing pace and this growth is reflected in the present volume of Studies in Natural Products Chemistry, which is the 20th of this series. The first 20 volumes were largely devoted to structure and synthesis of various classes of natural products, irrespective of their bioactivity. Subsequent volumes of this series will however be devoted to the chemistry of bioactive natural products and will therefore a departure from the earlier volumes.The present volume contains contributions from a number of eminent scientists and covers interesting reviews on terpenes, alkaloids and other types of natural products reported from terrestrial and marine sources. Comprehensive indexes covering all the 20 volumes have been prepared which include a Cumulative General Subject Index along with more focused Cumulative Indices on Organic Synthesis, Pharmacological Activity and Biological Source. This comprehensive indexing of the volumes should make the entire series much more valuable and user-friendly.

Download or read book Studies on Cyclization Reactions Initiated by Benzylic Cations Derived from Benzylic Alcohols and Quinone Methides written by Rogelio Perez Frutos and published by . This book was released on 1993 with total page 466 pages. Available in PDF, EPUB and Kindle. Book excerpt:

Download or read book Highlights in Bioorganic Chemistry written by Carsten Schmuck and published by John Wiley & Sons. This book was released on 2006-01-24 with total page 600 pages. Available in PDF, EPUB and Kindle. Book excerpt: This is a fascinating introduction to the topic. Spanning the spectrum of nucleic acid chemistry, carbohydrates, peptides, molecular recognition, biosynthesis and natural biosynthesis, right up to medical and biophysical chemistry, the book provides advanced students and those already working in the field with a balanced overview. In more than 30 contributions, a new generation of recognized scientists gives an account of the latest research in such areas as * Artificial receptors for the stabilization of ß-sheet structures * Carbohydrate recognition by artificial receptors * Combinatorial chemistry as a tool for the discovery of catalysts * The interaction of NO and peroxynitrite with hemoglobin and myoglobin * Inhibitors against human mast-cell-tryptase as a potential approach to conquering asthma * The selectivity of DNA replication. A readily accessible survey for everyone wishing to stay abreast of developments. With a Foreword by Ronald Breslow.

Download or read book Quinone Methides as Electrophilic Sinks written by Jon Douglas Rainier and published by . This book was released on 1993 with total page 940 pages. Available in PDF, EPUB and Kindle. Book excerpt:

Download or read book Natural Product Biosynthesis written by Christopher T. Walsh and published by Royal Society of Chemistry. This book was released on 2017-04-28 with total page 787 pages. Available in PDF, EPUB and Kindle. Book excerpt: This textbook describes the types of natural products, the biosynthetic pathways that enable the production of these molecules, and an update on the discovery of novel products in the post-genomic era.

Download or read book Photogeneration and Chemistry of Quinone Methides from Hydroxybenzyl Alcohols written by and published by . This book was released on 1999 with total page pages. Available in PDF, EPUB and Kindle. Book excerpt:

Download or read book Advances in Physical Organic Chemistry written by John P. Richard and published by Academic Press. This book was released on 2011-11-29 with total page 273 pages. Available in PDF, EPUB and Kindle. Book excerpt: Advances in Physical Organic Chemistry provides the chemical community with authoritative and critical assessments of the many aspects of physical organic chemistry. The field is a rapidly developing one, with results and methodologies finding application from biology to solid state physics. Reviews the application of quantitative and mathematical methods towards understanding chemical problems Covers organic, organometallic, bioorganic, enzymes and materials topics

Download or read book Studies in Natural Products Chemistry written by and published by Elsevier. This book was released on 2014-03-05 with total page 491 pages. Available in PDF, EPUB and Kindle. Book excerpt: Natural products in the plant and animal kingdom offer a huge diversity of chemical structures that are the result of biosynthetic processes that have been modulated over the millennia through genetic effects. With the rapid developments in spectroscopic techniques and accompanying advances in high-throughput screening techniques, it has become possible to isolate and then determine the structures and biological activity of natural products rapidly, thus opening up exciting new opportunities in the field of new drug development to the pharmaceutical industry.The series also covers the synthesis or testing and recording of the medicinal properties of natural products, providing cutting edge accounts of the fascinating developments in the isolation, structure elucidation, synthesis, biosynthesis and pharmacology of a diverse array of natural products. - Describes the chemistry of bioactive natural products - Contains contributions by leading authorities in the field - Presents exciting sources of new pharmacophores

Download or read book Studies in Natural Product Chemistry written by Atta-ur Rahman and published by Elsevier. This book was released on 2023-05-08 with total page 512 pages. Available in PDF, EPUB and Kindle. Book excerpt: Natural products in the plant and animal kingdom offer a huge diversity of chemical structures that are the result of biosynthetic processes that have been modulated over the millennia through genetic effects. With the rapid developments in spectroscopic techniques and accompanying advances in high-throughput screening techniques, it has become possible to isolate and then determine the structures and biological activity of natural products rapidly, thus opening up exciting opportunities in the field of new drug development to the pharmaceutical industry. Studies in Natural Products Chemistry covers the synthesis or testing and recording of the medicinal properties of natural products, providing cutting edge accounts of the fascinating developments in the isolation, structure elucidation, synthesis, biosynthesis and pharmacology of a diverse array of bioactive natural products. - Focuses on the chemistry of bioactive natural products - Contains contributions by leading authorities in the field - Presents sources of new pharmacophores