Download or read book Structural Characterisation of Amorphous Materials by Solid State NMR written by Neil Bruce Mollison and published by . This book was released on 2002 with total page 0 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Download or read book Amorphous Solid Dispersions written by Navnit Shah and published by Springer. This book was released on 2014-11-21 with total page 702 pages. Available in PDF, EPUB and Kindle. Book excerpt: This volume offers a comprehensive guide on the theory and practice of amorphous solid dispersions (ASD) for handling challenges associated with poorly soluble drugs. In twenty-three inclusive chapters, the book examines thermodynamics and kinetics of the amorphous state and amorphous solid dispersions, ASD technologies, excipients for stabilizing amorphous solid dispersions such as polymers, and ASD manufacturing technologies, including spray drying, hot melt extrusion, fluid bed layering and solvent-controlled micro-precipitation technology (MBP). Each technology is illustrated by specific case studies. In addition, dedicated sections cover analytical tools and technologies for characterization of amorphous solid dispersions, the prediction of long-term stability, and the development of suitable dissolution methods and regulatory aspects. The book also highlights future technologies on the horizon, such as supercritical fluid processing, mesoporous silica, KinetiSol®, and the use of non-salt-forming organic acids and amino acids for the stabilization of amorphous systems. Amorphous Solid Dispersions: Theory and Practice is a valuable reference to pharmaceutical scientists interested in developing bioavailable and therapeutically effective formulations of poorly soluble molecules in order to advance these technologies and develop better medicines for the future.
Download or read book Structure and Relaxation in Amorphous Materials Studied by Solid State NMR and Computer Simulations written by Magesh Nandagopal and published by . This book was released on 2006 with total page 242 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Download or read book Solid State NMR in Materials Science written by Vladimir I. Bakhmutov and published by CRC Press. This book was released on 2011-12-19 with total page 283 pages. Available in PDF, EPUB and Kindle. Book excerpt: Solid-state NMR is a powerful physical method widely applied in modern fundamental and applied science, medicine, and industry. Its role is particularly valuable in materials chemistry due to the capability of solid-state NMR to rapidly solve tasks connected with structural descriptions of complex systems on macro and/or molecular levels, and the identification of the dynamics often responsible for complex systems mechanical properties. Written for non-specialists, Solid-State NMR in Materials Science: Principles and Applications introduces the general physical principles of pulsed NMR, by including elements of the theory and practice in the registration of NMR signals, and by explaining different NMR equipment. After the preliminaries, the book covers: The theory and features of solid-state NMR and nuclear relaxation in solids, including dynamics of materials Different materials, diamagnetic and paramagnetic, from metals and metal clusters to amorphous composites The methodology of collection and interpretations of solid-state NMR data, including strategies and criteria for structural characterizations of different materials Practical examples of multinuclear NMR and relaxation experiments as well as interpretations of data obtained Numerous solid-state NMR experiments performed for various materials to evaluate their structure and dynamics Written in clear and simple language, this book includes clear illustrations, numerous examples, and detailed bibliographies. It an excellent reference not only for young and experienced researchers, but also for students interested in a future in materials science.
Download or read book Solid State NMR written by Klaus Müller and published by John Wiley & Sons. This book was released on 2021-06-23 with total page 560 pages. Available in PDF, EPUB and Kindle. Book excerpt: Solid State NMR A thorough and comprehensive textbook covering the theoretical background, experimental approaches, and major applications of solid-state NMR spectroscopy Nuclear Magnetic Resonance (NMR) spectroscopy is a powerful non-destructive technique capable of providing information about the molecular structure and dynamics of molecules. Alongside solution-state NMR, a well-established technique to study chemical structures and investigate physico-chemical properties of molecules in solutions, solid-state NMR (SSNMR) offers many exciting possibilities for the analysis of solid and soft materials across scientific fields. SSNMR shows unique capabilities for a detailed investigation of structural and dynamic properties of materials over wide space and time ranges. For this reason, and thanks to significant advances in the past several years, the application of SSNMR to materials is rapidly increasing in disciplines such as chemistry, physics, and materials and life sciences. Solid State NMR: Principles, Methods, and Applications offers a systematic introduction to the theory, methodological concepts, and major experimental methods of SSMR spectroscopy. Exploring the unique potential of SSNMR for the structural and dynamic characterization of soft and either amorphous or crystalline solid materials, this comprehensive textbook provides foundational knowledge and recent developments of SSNMR, covering physical and theoretical background, experimental methods, and applications to pharmaceuticals, polymers, inorganic and hybrid materials, liquid crystals, and model membranes. Written by two expert authors to ensure a clear and consistent presentation of the subject, this textbook: Includes a brief introduction to the historical aspects and broad theoretical background of solid-state NMR spectroscopy Provides helpful illustrations to explain the various SSNMR concepts and methods Features accessible descriptive text with self-consistent use of quantum mechanics Covers the experimental aspects of SSNMR spectroscopy and in particular a description of many useful pulse sequences Contains references to relevant literature Solid State NMR: Principles, Methods, and Applications is the ideal textbook for university courses on SSNMR, advanced spectroscopies, and a valuable single-volume reference for spectroscopists, chemists, and researchers in the field of materials.
Download or read book Solid State Characterization of Pharmaceuticals written by Richard A. Storey and published by John Wiley & Sons. This book was released on 2011-03-31 with total page 557 pages. Available in PDF, EPUB and Kindle. Book excerpt: The field of solid state characterization is central to the pharmaceutical industry, as drug products are, in an overwhelming number of cases, produced as solid materials. Selection of the optimum solid form is a critical aspect of the development of pharmaceutical compounds, due to their ability to exist in more than one form or crystal structure (polymorphism). These polymorphs exhibit different physical properties which can affect their biopharmaceutical properties. This book provides an up-to-date review of the current techniques used to characterize pharmaceutical solids. Ensuring balanced, practical coverage with industrial relevance, it covers a range of key applications in the field. The following topics are included: Physical properties and processes Thermodynamics Intellectual guidance X-ray diffraction Spectroscopy Microscopy Particle sizing Mechanical properties Vapour sorption Thermal analysis & Calorimetry Polymorph prediction Form selection
Download or read book Structural Characterization of Noncrystalline Solids and Glasses Using Solid State NMR written by Hellmut Eckert and published by . This book was released on 1992 with total page 135 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Download or read book Structural Characterization of Noncrystalline Solids and Glasses Using Solid State NMR written by Hellmut Eckert and published by . This book was released on 1992 with total page 135 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Download or read book Local Structural Characterisation written by Duncan W. Bruce and published by John Wiley & Sons. This book was released on 2013-07-31 with total page 298 pages. Available in PDF, EPUB and Kindle. Book excerpt: Inorganic materials are at the heart of many contemporary real-world applications, in electronic devices, drug delivery, bio-inspired materials and energy storage and transport. In order to underpin novel synthesis strategies both to facilitate these applications and to encourage new ones, a thorough review of current and emerging techniques for materials characterisation is needed. Examining important techniques that allow investigation of the structures of inorganic materials on the local atomic scale, Local Structural Characterisation discusses: Solid-State NMR Spectroscopy X-Ray Absorption and Emission Spectroscopy Neutrons and Neutron Spectroscopy EPR Spectroscopy of Inorganic Materials Analysis of Functional Materials by X-Ray Photoelectron Spectroscopy This addition to the Inorganic Materials Series provides a detailed and thorough review of these spectroscopic techniques and emphasises the interplay between chemical synthesis and physical characterisation.
Download or read book Defects and Disorder in Crystalline and Amorphous Solids written by Richard Catlow and published by Springer Science & Business Media. This book was released on 2012-12-06 with total page 511 pages. Available in PDF, EPUB and Kindle. Book excerpt: The study of defects and disorder in solids remains a central topic in solid state science. Developments in the field continue to be promoted by new experimental and theoretical techniques, while further impetus for the study of disorder in solids is provided by the growing range of applications of solid state materials in which disorder at the atomic level plays a crucial rOle. In this book we attempt to present a survey of fundamental and applied aspects of the field. We consider the basic aspects of defective crystalline and amorphous solids. We discuss recent studies of structural, electronic, transport, thermodynamic and spectroscopic properties of such materials. Experimental and theoretical methodologies are reviewed, and detailed consideration is given to materials such as fast ion conductors and amorphous semiconductors that are of importance in an applied context. Any survey of this large field is necessarily selective. We have chosen to emphasise insulating (especially oxidic) and semi-conducting materials. But many of the approaches and techniques we describe apply generally across the entire field of solid state science. This volume is based on a NATO ASI held at the Residencia Santa Teresa de Jesus, Madrid in September 1991. The Editor is grateful to the NATO Scientific Affairs Division for their sponsorship of this School. Thanks are also due to all who participated in and lectured at the school, but especially to the organising committee of A. V. Chadwick, G. N. Greaves, M. Grigorkiewicz, J. H. Harding and S. Kalbitzer. C. R. A.
Download or read book World Scientific Reference Of Amorphous Materials The Structure Properties Modeling And Main Applications In 3 Volumes written by and published by World Scientific. This book was released on 2020-12-28 with total page 1548 pages. Available in PDF, EPUB and Kindle. Book excerpt: Amorphous solids (including glassy and non-crystalline solids) are ubiquitous since the vast majority of solids naturally occurring in our world are amorphous. Although the field is diverse and complex, this three-volume set covers the vast majority of the important concepts needed to understand these materials and their principal practical applications. One volume discusses the most important subset of amorphous insulators, namely oxide glasses; the other two volumes discuss the most important subsets of amorphous semiconductors, namely tetrahedrally coordinated amorphous semiconductors and amorphous and glassy chalcogenides. Together these three volumes provide a comprehensive set of theoretical concepts and practical information needed to become conversant in the field of amorphous materials. They are suitable for advanced graduate students, postdoctoral research associates, and researchers wishing to change fields or sub-fields.The topics covered in these three volumes include (1) concepts for understanding the structures of amorphous materials, (2) techniques to characterize the structural, electronic, and optical properties of amorphous materials, (3) the roles of defects in affecting the electronic and optical properties of amorphous materials, and (4) the concepts for understanding practical devices and other applications of amorphous materials. Applications discussed in these volumes include transistors, solar cells, displays, bolometers, fibers, non-volatile memories, vidicons, photoresists, and optical disks.
Download or read book Solid State Properties of Pharmaceutical Materials written by Stephen R. Byrn and published by John Wiley & Sons. This book was released on 2017-08-28 with total page 420 pages. Available in PDF, EPUB and Kindle. Book excerpt: Presents a detailed discussion of important solid-state properties, methods, and applications of solid-state analysis Illustrates the various phases or forms that solids can assume and discussesvarious issues related to the relative stability of solid forms and tendencies to undergo transformation Covers key methods of solid state analysis including X-ray powder diffraction, thermal analysis, microscopy, spectroscopy, and solid state NMR Reviews critical physical attributes of pharmaceutical materials, mainly related to drug substances, including particle size/surface area, hygroscopicity, mechanical properties, solubility, and physical and chemical stability Showcases the application of solid state material science in rational selection of drug solid forms, analysis of various solid forms within drug substance and the drug product, and pharmaceutical product development Introduces appropriate manufacturing and control procedures using Quality by Design, and other strategies that lead to safe and effective products with a minimum of resources and time
Download or read book Multidimensional Solid State NMR and Polymers written by Klaus Schmidt-Rohr and published by Elsevier. This book was released on 2012-12-02 with total page 501 pages. Available in PDF, EPUB and Kindle. Book excerpt: NMR spectroscopy is the most valuable and versatile analytical tool in chemistry. While excellent monographs exist on high-resolution NMR in liquids and solids, this is the first book to address multidimensional solid-state NMR. Multidimensional techniques enable researchers to obtain detailed information about the structure, dynamics, orientation, and phase separation of solids, which provides the basis of a better understanding of materials properties on the molecular level.Dramatic progress-much of it pioneered by the authors-has been achieved in this area, especially in synthetic polymers. Solid-state NMR now favorably competes with well-established techniques, such as light, x-ray, or neutron scattering, electron microscopy, and dielectric and mechanical relaxation.The application of multidimensional solid-state NMR inevitably involves use of concepts from different fields of science. This book also provides the first comprehensive treatment of both the new experimental techniques and the theoretical concepts needed in more complex data analysis. The text addresses spectroscopists and polymer scientists by treating the subject on different levels; descriptive, technical, and mathematical approaches are used when appropriate. It presents an overview of new developments with numerous experimental examples and illustrations, which will appeal to readers interested in both the information content as well as the potential of solid-state NMR. The book also contains many previously unpublished details that will be appreciated by those who want to perform the experiments. The techniques described are applicable not only to the study of synthetic polymers but to numerous problems in solid-state physics, chemistry, materials science, and biophysics. - Presents original theories and new perspectives on scattering techniques - Provides a systematic treatment of the whole subject - Gives readers access to previously unpublished material - Includes extensive illustrations
Download or read book Fundamentals of Amorphous Solids written by Zbigniew H. Stachurski and published by John Wiley & Sons. This book was released on 2015-03-09 with total page 274 pages. Available in PDF, EPUB and Kindle. Book excerpt: Long awaited, this textbook fills the gap for convincing concepts to describe amorphous solids. Adopting a unique approach, the author develops a framework that lays the foundations for a theory of amorphousness. He unravels the scientific mysteries surrounding the topic, replacing rather vague notions of amorphous materials as disordered crystalline solids with the well-founded concept of ideal amorphous solids. A classification of amorphous materials into inorganic glasses, organic glasses, glassy metallic alloys, and thin films sets the scene for the development of the model of ideal amorphous solids, based on topology- and statistics-governed rules of three-dimensional sphere packing, which leads to structures with no short, mid or long-range order. This general model is then concretized to the description of specific compounds in the four fundamental classes of amorphous solids, as well as amorphous polyethylene and poly(methyl)methacrylate, emphasizing its versatility and descriptive power. Finally, he includes example applications to indicate the abundance of amorphous materials in modern-day technology, thus illustrating the importance of a better understanding of their structure and properties. Equally ideal as supplementary reading in courses on crystallography, mineralogy, solid state physics, and materials science where amorphous materials have played only a minor role until now.
Download or read book Structural Characterization of Aluminum Oxide Thin Films Using Solid state NMR written by Yvonne Afriyie and published by . This book was released on 2018 with total page 66 pages. Available in PDF, EPUB and Kindle. Book excerpt: Aluminum is an ideal metal for solution-processed oxide dielectrics because it can form polymerized hydroxo networks in aqueous solution and dense amorphous oxide dielectrics by vacuum methods. Atomic layer deposition (ALD) is one of the traditional vacuum methods for thin film deposition, however, ALD is not the most economically feasible method for thin film fabrication due to high operational cost and limitations in large surface-area applications. Solution deposition is a more economical deposition method which is more cost-saving and ideal for large surface area thin film fabrication. The behavior of the solution-solid structural conversion remains an enigma; thus, this research seeks to understand the structural transformation of thin films from solution to solid in order to fabricate films with optimal properties.Aluminum oxide (AlxOy) thin films prepared from aqueous solution-deposited cluster precursors have been proposed for use in devices such as high-k dielectrics in solar cell materials. The films are fabricated with different aluminum-derived precursors, spin-coated on a substrate and annealed at a range of temperatures. The low temperature range of these films are amorphous, therefore lack long range order. Solid-state nuclear magnetic resonance (ssNMR) can be used to determine the amorphous structure of these materials. Herein, a combination of X-ray diffraction (XRD), and NMR techniques are used to elucidate the transformation of these thin films as they are annealed to high temperatures.
Download or read book Properties and Applications of Amorphous Materials written by M.F. Thorpe and published by Springer Science & Business Media. This book was released on 2012-12-06 with total page 451 pages. Available in PDF, EPUB and Kindle. Book excerpt: The aim of this NATO ASI has been to present an up-to-date overview of current areas of interest in amorphous materials, with particular emphasis on electronic properties and device applications. In order to limit the material to a manageable amount, the meeting was concerned almost exclusively with semiconducting materials. This volume should be regarded as a follow-on to the NATO ASI held in Sozopol, Bulgaria in 1996 and published as "Amorphous Insulators and Semiconductors" edited by M.F. Thorpe and M.1. Mitkova (Kluwer Academic Publishers, NATO ASI series, 3 High Technology - Vol. 23). The lectures and seminars fill the gap between graduate courses and research seminars. The lecturers and seminar speakers were chosen as experts in their respective areas, and the lectures and seminars that were given are presented in this volume. During the first week of the meeting, an emphasis was placed on introductory lectures while the second week focused more on research seminars. There were two very good poster sessions that generated a lot of discussion, but these are not reproduced in this volume as the editors wanted to have only larger contributions to make the proceedings more coherent.
Download or read book Structural Characterization of Complex Inorganic Materials Using Solid state NMR Spectroscopy written by Hua Guo and published by . This book was released on 2021 with total page pages. Available in PDF, EPUB and Kindle. Book excerpt:
