Download or read book Stimulus Properties of Drugs written by Travis. Thompson and published by Springer Science & Business Media. This book was released on 2012-12-06 with total page 224 pages. Available in PDF, EPUB and Kindle. Book excerpt: Behavioral pharmacology represents a relatively recent scientific enterprise, the development of which can be followed by plotting the publication of major conceptual papers, review articles, and books. Dews (1955), Sidman (1955), and Brady (1956) published some of the first methodologically significant papers, changing the way both psychologists and pharmacologists viewed the analysis of the behavioral actions of drugs. Dews and Morse (1961), Cook and Kelleher (1963), Gollub and Brady (1965), and Weiss and Laties (1969) kept the field abreast of major developments in the study of behavioral mechanisms of drug action. In 1968, the first textbook in the field was published (Thompson and Schuster), followed by a book of readings covering the preceding 15 years of the field (Thompson, Pickens, and Meisch, 1970). The first attempt to outline a set of generalizations concerning behavioral mechanisms of drug actions was puhlished in 1968 by Kelleher and Morse. As behavioral pharmacology developed, it became clear that demonstrations that drugs affect hehavior were relatively uninteresting. It was the mechanisms by which these effects are hrought about that was of concern. While other aspects of pharmacology have been concerned with biochemical, physiological, and in some cases biophysical accounts of drug actions, behavioral pharmacology has dealt with behavioral mechanisms . . . that is, "any verifiable description of a drug's effects which can he shown to uniquely covary with a specific measured 'response'. Generally, this relation can be subsumed under some more general set of relations or principles" (Thompson, Pickens, and Meisch, 1970, p. I).
Download or read book Discriminative Stimulus Properties of Drugs written by Harbans Lal and published by Springer Science & Business Media. This book was released on 2013-03-13 with total page 284 pages. Available in PDF, EPUB and Kindle. Book excerpt: As one who has gone down the wayward path from "pure" organic chemistry to biochemistry to pharmacology, I was not quite prepared to go all the way - into the field of discriminable stimuli. The organizer of the symposium on discriminable stimuli induced by drugs, Dr. Harbans Lal, did seduce me into attending. Having lost my behavioral virginity, I now stare with open eyes at the field. One item in particular at this meeting exemplifies to me the power of such techniques. Dr. Albert Weissman mentioned the problem he tackled with getting rats to discriminate between saline and dilute solutions of aspirin. Under ordinary circumstances, the animals could not perform this task. However, if the animals were sensitized by injection of prostaglan din into their foot pads, then they were capable of discriminating even very dilute solutions of aspirin. In a sense, Al had created a model of the human arthritic who can jolly well tell if you have given him an aspirin or a salt tablet. The reader of this volume will find it a good introduction to the utilization of discriminable stimuli induced by drugs. After a preface by the organizer, two experts discuss basic principles in separate chapters. One of these chapters places emphasis on the drugs; the other places emphasis on the induced cues and states.
Download or read book Stimulus Properties of Drugs written by Francis C. Colpaert and published by North-Holland. This book was released on 1978 with total page 592 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Download or read book Discriminative Stimulus Properties of Drugs written by Harbans Lal and published by . This book was released on 1977-04 with total page 252 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Download or read book Psychopharmacology of Aversively Motivated Behavior written by H. Anisman and published by Springer Science & Business Media. This book was released on 2012-12-06 with total page 717 pages. Available in PDF, EPUB and Kindle. Book excerpt: During the past two decades, remarkable advances have been made in psychopharmacology, resulting in increased demands for journal space (witness the large number of journals that cater primarily or exclusively to this topic). Concomitantly, a need developed for more integration of the currently available data. To this end, numerous edited volumes in psycho pharmacology have appeared which have been primarily concerned with the role of a particular drug or system in modulating a wide variety of behaviors. While such texts have been most useful in elucidating drug mechanisms and the etiology of a number of behaviors, few attempts have been made to evaluate and integrate pharmacological treatments within a single behavioral category. Specifically, the researcher interested in understanding a given behavior from a neurochemical point of view must consult several texts, each dealing with a different chemical or system. When texts are obtained covering a broad spectrum of systems, they also invariably deal with many different behaviors, thus not allowing for complete integration within a behavioral category. The present volume was planned to meet the needs of the scientist interested in understanding neurochemical mechanisms underlying aversively motivated behavior, as well as drug effects thereon. In organizing the contents of this text, it quickly became apparent that any attempt to provide a complete overview of behavioral and pharmacological information pertaining to aversive situations was not practical for at least two reasons.
Download or read book Transduction Mechanisms of Drug Stimuli written by Francis C. Colpaert and published by Springer Science & Business Media. This book was released on 2012-12-06 with total page 255 pages. Available in PDF, EPUB and Kindle. Book excerpt: In this book the latest data available on transduction mechanisms of drug stimuli are presented. A common theme underlying the chapter in this volume is the recognition that drugs can act as stimuli, in much the same manner as external events do. Accordingly, the papers focus on the mechanisms by which these stimuli are transduced at different levels of analysis, such as the behavioral, pharmacological, and molecular levels. Some chapters discuss the mechanisms of transduction of the discriminative effects of several important classes of drugs, while others deal with the methods and research strategies by which these mechanisms can be analyzed. Collectively, the papers in this volume reflect the current status of knowledge in the rapidly expanding field of behavioral pharmacology.
Download or read book Methods of Assessing the Reinforcing Properties of Abused Drugs written by Michael A. Bozarth and published by Springer Science & Business Media. This book was released on 2012-12-06 with total page 658 pages. Available in PDF, EPUB and Kindle. Book excerpt: Methods of Assessing the Reinforcing Properties of Abused Drugs presents a synopsis of the preclinical procedures used to assess drug reinforcement. Researchers using one technique are provided with an overview of the other available methods, and clinicians who wish to evaluate drug abuse research reports can gain the necessary background from this volume. Although emphasis is placed on the methodological aspects of assessing drug reinforcement, some of the scientific conclusions derived from using these techniques are also presented. This edited collection offers a lasting framework for interpreting the results of current experimental findings.
Download or read book The Behavioral Neuroscience of Drug Discrimination written by Joseph H. Porter and published by Springer. This book was released on 2018-08-30 with total page 324 pages. Available in PDF, EPUB and Kindle. Book excerpt: The goal for this volume is to provide an up-to-date review of the discriminative stimulus properties of major psychoactive drug classes with an emphasis on how this paradigm enhances our understanding of these drugs and how these findings translate from animals to humans. The drug discrimination paradigm applies to both drugs of abuse and drugs for treating mental illnesses, and research from these studies has provided immense translational value for learning about the mechanisms responsible for drug effects in humans.
Download or read book Methods of Assessing the Reinforcing Properties of Abused Drugs written by Michael A. Bozarth and published by Springer. This book was released on 1987 with total page 680 pages. Available in PDF, EPUB and Kindle. Book excerpt: Methods of Assessing the Reinforcing Properties of Abused Drugs presents a synopsis of the preclinical procedures used to assess drug reinforcement. Researchers using one technique are provided with an overview of the other available methods, and clinicians who wish to evaluate drug abuse research reports can gain the necessary background from this volume. Although emphasis is placed on the methodological aspects of assessing drug reinforcement, some of the scientific conclusions derived from using these techniques are also presented. This edited collection offers a lasting framework for interpreting the results of current experimental findings.
Download or read book Methods of Behavior Analysis in Neuroscience written by Jerry J. Buccafusco and published by CRC Press. This book was released on 2000-08-29 with total page 341 pages. Available in PDF, EPUB and Kindle. Book excerpt: Using the most well-studied behavioral analyses of animal subjects to promote a better understanding of the effects of disease and the effects of new therapeutic treatments on human cognition, Methods of Behavior Analysis in Neuroscience provides a reference manual for molecular and cellular research scientists in both academia and the pharmaceutic
Download or read book Nonclinical Assessment of Abuse Potential for New Pharmaceuticals written by Carrie Markgraf and published by Academic Press. This book was released on 2015-07-14 with total page 320 pages. Available in PDF, EPUB and Kindle. Book excerpt: Nonclinical Assessment of Abuse Potential for New Pharmaceuticals offers a complete reference on the current international regulatory guidelines and details best practice methodology for the three standard animal models used to evaluate abuse potential: physical dependence, self-administration and drug discrimination. This book also includes chapters on alternative models and examples of when you should use these alternatives. Case histories are provided at the end of the book to show how the data generated from the animal models play a pivitol role in the submission package for a new drug. By incorporating all of this information into one book, Nonclinical Assessment of Abuse Potential for New Pharmaceuticals is your single resource for everything you need to know to understand and implement the assessment of abuse liability. Provides a consolidated overview of the complex regulatory landscape Offers best practice methodology for conducting animal studies, including selection of doses and positive control agents that will help you improve your own abuse potential studies Includes real-life examples to illustrate how nonclinical data fit into the submission strategy
Download or read book Drug Targeting and Stimuli Sensitive Drug Delivery Systems written by Alexandru Mihai Grumezescu and published by William Andrew. This book was released on 2018-05-21 with total page 836 pages. Available in PDF, EPUB and Kindle. Book excerpt: Drug Targeting and Stimuli Sensitive Drug Delivery Systems covers recent advances in the area of stimuli sensitive drug delivery systems, providing an up-to-date overview of the physical, chemical, biological and multistimuli-responsive nanosystems. In addition, the book presents an analysis of clinical status for different types of nanoplatforms. Written by an internationally diverse group of researchers, it is an important reference resource for both biomaterials scientists and those working in the pharmaceutical industry who are looking to help create more effective drug delivery systems. Shows how the use of nanomaterials can help target a drug to specific tissues and cells Explores the development of stimuli-responsive drug delivery systems Includes case studies to showcase how stimuli responsive nanosystems are used in a variety of therapies, including camptothecin delivery, diabetes and cancer therapy
Download or read book Advances in Behavioral Pharmacology written by Travis Thompson and published by Elsevier. This book was released on 2013-10-22 with total page 278 pages. Available in PDF, EPUB and Kindle. Book excerpt: Advances in Behavioral Pharmacology, Volume 1 provides synthetic and analytic reviews of significant areas of behavioral pharmacology, particularly the behavioral mechanisms of drug action. The book presents papers on the behavioral pharmacology of the tetrahydrocannabinols; on infrahuman ethanol self-administration; and on the discriminative stimulus properties of drugs. The text then describes various methods used to study the effects of drugs on discrimination; signal detection (SDT), which attempts to separate effects of variables on discrimination processes or capacity (sensitivity) from effects on the subject's criterion; and some of the uses of this model in behavioral pharmacology. The rate-dependency of the behavioral effects of amphetamine, as well as some of the major events in the history of behavioral pharmacology are also considered. The book concludes by tackling the status of behavioral pharmacology. Behavioral pharmacologists, pharmacologists, physicians, and students taking pharmacology and medicine will find the book useful.
Download or read book Introduction to Behavioral Pharmacology written by Thomas Byrne and published by New Harbinger Publications. This book was released on 2000-05-01 with total page 254 pages. Available in PDF, EPUB and Kindle. Book excerpt: There are hundreds, if not thousands, of substances that are used to modify behavior. While different classes of substances have known effects, one has only to see a group of people drinking to excess to recognize that not everyone responds in the same way to a given substance. Why do substances have the behavioral effects they do, and why do individuals vary in their responses to them? This book provides a conceptual framework for answering such questions. Introduction to Behavioral Pharmacology includes a short overview of behavioral analysis and general pharmacology, followed by detailed discussion of assessment of drug effects, the stimulus properties of drugs, drug abuse, and more.
Download or read book Occasion Setting written by American Psychological Association and published by Amer Psychological Assn. This book was released on 1998-01-01 with total page 440 pages. Available in PDF, EPUB and Kindle. Book excerpt: Content Description #Includes bibliographical references and index.
Download or read book Biomedical Applications of Polymeric Materials and Composites written by Raju Francis and published by John Wiley & Sons. This book was released on 2016-12-19 with total page 414 pages. Available in PDF, EPUB and Kindle. Book excerpt: With its content taken from only the very latest results, this is an extensive summary of the various polymeric materials used for biomedical applications. Following an introduction listing various functional polymers, including conductive, biocompatible and conjugated polymers, the book goes on to discuss different synthetic polymers that can be used, for example, as hydrogels, biochemical sensors, functional surfaces, and natural degradable materials. Throughout, the focus is on applications, with worked examples for training purposes as well as case studies included. The whole is rounded off with a look at future trends.
Download or read book Moderate and Deep Sedation in Clinical Practice written by Richard D. Urman and published by Cambridge University Press. This book was released on 2012-02-09 with total page 343 pages. Available in PDF, EPUB and Kindle. Book excerpt: A concise, practical handbook giving up-to-date, evidence based, 'how to' guidance on safe, effective procedural sedation.
