Download or read book An Introduction to Statistical Genetic Data Analysis written by Melinda C. Mills and published by MIT Press. This book was released on 2020-02-18 with total page 433 pages. Available in PDF, EPUB and Kindle. Book excerpt: A comprehensive introduction to modern applied statistical genetic data analysis, accessible to those without a background in molecular biology or genetics. Human genetic research is now relevant beyond biology, epidemiology, and the medical sciences, with applications in such fields as psychology, psychiatry, statistics, demography, sociology, and economics. With advances in computing power, the availability of data, and new techniques, it is now possible to integrate large-scale molecular genetic information into research across a broad range of topics. This book offers the first comprehensive introduction to modern applied statistical genetic data analysis that covers theory, data preparation, and analysis of molecular genetic data, with hands-on computer exercises. It is accessible to students and researchers in any empirically oriented medical, biological, or social science discipline; a background in molecular biology or genetics is not required. The book first provides foundations for statistical genetic data analysis, including a survey of fundamental concepts, primers on statistics and human evolution, and an introduction to polygenic scores. It then covers the practicalities of working with genetic data, discussing such topics as analytical challenges and data management. Finally, the book presents applications and advanced topics, including polygenic score and gene-environment interaction applications, Mendelian Randomization and instrumental variables, and ethical issues. The software and data used in the book are freely available and can be found on the book's website.
Download or read book Quantitative and Statistical Research Methods written by William E. Martin and published by John Wiley & Sons. This book was released on 2012-07-09 with total page 498 pages. Available in PDF, EPUB and Kindle. Book excerpt: Quantitative and Statistical Research Methods This user-friendly textbook teaches students to understand and apply procedural steps in completing quantitative studies. It explains statistics while progressing through the steps of the hypothesis-testing process from hypothesis to results. The research problems used in the book reflect statistical applications related to interesting and important topics. In addition, the book provides a Research Analysis and Interpretation Guide to help students analyze research articles. Designed as a hands-on resource, each chapter covers a single research problem and offers directions for implementing the research method from start to finish. Readers will learn how to: Pinpoint research questions and hypotheses Identify, classify, and operationally define the study variables Choose appropriate research designs Conduct power analysis Select an appropriate statistic for the problem Use a data set Conduct data screening and analyses using SPSS Interpret the statistics Write the results related to the problem Quantitative and Statistical Research Methods allows students to immediately, independently, and successfully apply quantitative methods to their own research projects.
Download or read book Statistical Methods in Water Resources written by D.R. Helsel and published by Elsevier. This book was released on 1993-03-03 with total page 539 pages. Available in PDF, EPUB and Kindle. Book excerpt: Data on water quality and other environmental issues are being collected at an ever-increasing rate. In the past, however, the techniques used by scientists to interpret this data have not progressed as quickly. This is a book of modern statistical methods for analysis of practical problems in water quality and water resources.The last fifteen years have seen major advances in the fields of exploratory data analysis (EDA) and robust statistical methods. The 'real-life' characteristics of environmental data tend to drive analysis towards the use of these methods. These advances are presented in a practical and relevant format. Alternate methods are compared, highlighting the strengths and weaknesses of each as applied to environmental data. Techniques for trend analysis and dealing with water below the detection limit are topics covered, which are of great interest to consultants in water-quality and hydrology, scientists in state, provincial and federal water resources, and geological survey agencies.The practising water resources scientist will find the worked examples using actual field data from case studies of environmental problems, of real value. Exercises at the end of each chapter enable the mechanics of the methodological process to be fully understood, with data sets included on diskette for easy use. The result is a book that is both up-to-date and immediately relevant to ongoing work in the environmental and water sciences.
Download or read book Study Design and Statistical Analysis written by Mitchell Katz and published by Cambridge University Press. This book was released on 2006-06-22 with total page 229 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book takes the reader through the entire research process: choosing a question, designing a study, collecting the data, using univariate, bivariate and multivariable analysis, and publishing the results. It does so by using plain language rather than complex derivations and mathematical formulae. It focuses on the nuts and bolts of performing research by asking and answering the most basic questions about doing research studies. Making good use of numerous tables, graphs and tips, this book helps to demystify the process. A generous number of up-to-date examples from the clinical literature give an illustrated and practical account of how to use multivariable analysis.
Download or read book The Analysis of Case control Studies written by Norman E. Breslow and published by . This book was released on 1980 with total page 352 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Download or read book Statistical Analysis Quick Reference Guidebook written by Alan C. Elliott and published by SAGE. This book was released on 2007 with total page 280 pages. Available in PDF, EPUB and Kindle. Book excerpt: A practical `cut to the chase′ handbook that quickly explains the when, where, and how of statistical data analysis as it is used for real-world decision-making in a wide variety of disciplines. In this one-stop reference, the authors provide succinct guidelines for performing an analysis, avoiding pitfalls, interpreting results and reporting outcomes.
Download or read book Communication Research Statistics written by John C. Reinard and published by SAGE Publications. This book was released on 2006-04-20 with total page 604 pages. Available in PDF, EPUB and Kindle. Book excerpt: "While most books on statistics seem to be written as though targeting other statistics professors, John Reinard′s Communication Research Statistics is especially impressive because it is clearly intended for the student reader, filled with unusually clear explanations and with illustrations on the use of SPSS. I enjoyed reading this lucid, student-friendly book and expect students will benefit enormously from its content and presentation. Well done!" --John C. Pollock, The College of New Jersey Written in an accessible style using straightforward and direct language, Communication Research Statistics guides students through the statistics actually used in most empirical research undertaken in communication studies. This introductory textbook is the only work in communication that includes details on statistical analysis of data with a full set of data analysis instructions based on SPSS 12 and Excel XP. Key Features: Emphasizes basic and introductory statistical thinking: The basic needs of novice researchers and students are addressed, while underscoring the foundational elements of statistical analyses in research. Students learn how statistics are used to provide evidence for research arguments and how to evaluate such evidence for themselves. Prepares students to use statistics: Students are encouraged to use statistics as they encounter and evaluate quantitative research. The book details how statistics can be understood by developing actual skills to carry out rudimentary work. Examples are drawn from mass communication, speech communication, and communication disorders. Incorporates SPSS 12 and Excel: A distinguishing feature is the inclusion of coverage of data analysis by use of SPSS 12 and by Excel. Information on the use of major computer software is designed to let students use such tools immediately. Companion Web Site! A dedicated Web site includes a glossary, data sets, chapter summaries, additional readings, links to other useful sites, selected "calculators" for computation of related statistics, additional macros for selected statistics using Excel and SPSS, and extra chapters on multiple discriminant analysis and loglinear analysis. Intended Audience: Ideal for undergraduate and graduate courses in Communication Research Statistics or Methods; also relevant for many Research Methods courses across the social sciences
Download or read book Small Clinical Trials written by Institute of Medicine and published by National Academies Press. This book was released on 2001-01-01 with total page 221 pages. Available in PDF, EPUB and Kindle. Book excerpt: Clinical trials are used to elucidate the most appropriate preventive, diagnostic, or treatment options for individuals with a given medical condition. Perhaps the most essential feature of a clinical trial is that it aims to use results based on a limited sample of research participants to see if the intervention is safe and effective or if it is comparable to a comparison treatment. Sample size is a crucial component of any clinical trial. A trial with a small number of research participants is more prone to variability and carries a considerable risk of failing to demonstrate the effectiveness of a given intervention when one really is present. This may occur in phase I (safety and pharmacologic profiles), II (pilot efficacy evaluation), and III (extensive assessment of safety and efficacy) trials. Although phase I and II studies may have smaller sample sizes, they usually have adequate statistical power, which is the committee's definition of a "large" trial. Sometimes a trial with eight participants may have adequate statistical power, statistical power being the probability of rejecting the null hypothesis when the hypothesis is false. Small Clinical Trials assesses the current methodologies and the appropriate situations for the conduct of clinical trials with small sample sizes. This report assesses the published literature on various strategies such as (1) meta-analysis to combine disparate information from several studies including Bayesian techniques as in the confidence profile method and (2) other alternatives such as assessing therapeutic results in a single treated population (e.g., astronauts) by sequentially measuring whether the intervention is falling above or below a preestablished probability outcome range and meeting predesigned specifications as opposed to incremental improvement.
Download or read book Statistical Analysis of Climate Extremes written by Manfred Mudelsee and published by Cambridge University Press. This book was released on 2020 with total page 213 pages. Available in PDF, EPUB and Kindle. Book excerpt: The risks posed by climate change and its effect on climate extremes are an increasingly pressing societal problem. This book provides an accessible overview of the statistical analysis methods which can be used to investigate climate extremes and analyse potential risk. The statistical analysis methods are illustrated with case studies on extremes in the three major climate variables: temperature, precipitation, and wind speed. The book also provides datasets and access to appropriate analysis software, allowing the reader to replicate the case study calculations. Providing the necessary tools to analyse climate risk, this book is invaluable for students and researchers working in the climate sciences, as well as risk analysts interested in climate extremes.
Download or read book Statistical Methods for Practice and Research written by Ajai S Gaur and published by SAGE Publications Pvt. Limited. This book was released on 2009-07-09 with total page 0 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book is designed to help the managers and researchers in solving statistical problems using SPSS and to help them understand how they can use various statistical tools for their own research problems. SPSS is a very powerful and user friendly computer package for data analyses. It can take data from most other file-types and generate tables, charts, plots, and descriptive statistics, and conduct complex statistical analyses. This book will help students, business managers, academics as well as practicing researchers to solve statistical problems using the latest version of SPSS (16.0). After providing a brief overview of SPSS and basic statistical concepts, the book covers: Descriptive statistics t-tests, chi-square tests, and ANOVA Correlation analysis Multiple and logistics regression Factor analysis and testing scale reliability Advanced data handling
Download or read book Handbook of Statistical Analysis and Data Mining Applications written by Ken Yale and published by Elsevier. This book was released on 2017-11-09 with total page 824 pages. Available in PDF, EPUB and Kindle. Book excerpt: Handbook of Statistical Analysis and Data Mining Applications, Second Edition, is a comprehensive professional reference book that guides business analysts, scientists, engineers and researchers, both academic and industrial, through all stages of data analysis, model building and implementation. The handbook helps users discern technical and business problems, understand the strengths and weaknesses of modern data mining algorithms and employ the right statistical methods for practical application. This book is an ideal reference for users who want to address massive and complex datasets with novel statistical approaches and be able to objectively evaluate analyses and solutions. It has clear, intuitive explanations of the principles and tools for solving problems using modern analytic techniques and discusses their application to real problems in ways accessible and beneficial to practitioners across several areas—from science and engineering, to medicine, academia and commerce. - Includes input by practitioners for practitioners - Includes tutorials in numerous fields of study that provide step-by-step instruction on how to use supplied tools to build models - Contains practical advice from successful real-world implementations - Brings together, in a single resource, all the information a beginner needs to understand the tools and issues in data mining to build successful data mining solutions - Features clear, intuitive explanations of novel analytical tools and techniques, and their practical applications
Download or read book How Many Subjects written by Helena Chmura Kraemer and published by SAGE. This book was released on 1987-09 with total page 128 pages. Available in PDF, EPUB and Kindle. Book excerpt: How Many Subjects? is a practical guide to sample size calculations and general principles of cost-effective research. It introduces a simple technique of statistical power analysis which allows researchers to compute approximate sample sizes and power for a wide variety of research designs. Because the same technique is used with only slight modifications for different statistical tests, researchers can easily compare the sample sizes required by different designs and tests to make cost-effective decisions in planning a study. These comparisons, emphasized throughout the book, demonstrate important principles of design, measurement and analysis that are rarely discussed in courses or textbooks.
Download or read book Practical Statistics for Data Scientists written by Peter Bruce and published by "O'Reilly Media, Inc.". This book was released on 2017-05-10 with total page 322 pages. Available in PDF, EPUB and Kindle. Book excerpt: Statistical methods are a key part of of data science, yet very few data scientists have any formal statistics training. Courses and books on basic statistics rarely cover the topic from a data science perspective. This practical guide explains how to apply various statistical methods to data science, tells you how to avoid their misuse, and gives you advice on what's important and what's not. Many data science resources incorporate statistical methods but lack a deeper statistical perspective. If you’re familiar with the R programming language, and have some exposure to statistics, this quick reference bridges the gap in an accessible, readable format. With this book, you’ll learn: Why exploratory data analysis is a key preliminary step in data science How random sampling can reduce bias and yield a higher quality dataset, even with big data How the principles of experimental design yield definitive answers to questions How to use regression to estimate outcomes and detect anomalies Key classification techniques for predicting which categories a record belongs to Statistical machine learning methods that “learn” from data Unsupervised learning methods for extracting meaning from unlabeled data
Download or read book Handbook of Statistical Methods for Case Control Studies written by Ørnulf Borgan and published by CRC Press. This book was released on 2018-06-27 with total page 536 pages. Available in PDF, EPUB and Kindle. Book excerpt: Handbook of Statistical Methods for Case-Control Studies is written by leading researchers in the field. It provides an in-depth treatment of up-to-date and currently developing statistical methods for the design and analysis of case-control studies, as well as a review of classical principles and methods. The handbook is designed to serve as a reference text for biostatisticians and quantitatively-oriented epidemiologists who are working on the design and analysis of case-control studies or on related statistical methods research. Though not specifically intended as a textbook, it may also be used as a backup reference text for graduate level courses. Book Sections Classical designs and causal inference, measurement error, power, and small-sample inference Designs that use full-cohort information Time-to-event data Genetic epidemiology About the Editors Ørnulf Borgan is Professor of Statistics, University of Oslo. His book with Andersen, Gill and Keiding on counting processes in survival analysis is a world classic. Norman E. Breslow was, at the time of his death, Professor Emeritus in Biostatistics, University of Washington. For decades, his book with Nick Day has been the authoritative text on case-control methodology. Nilanjan Chatterjee is Bloomberg Distinguished Professor, Johns Hopkins University. He leads a broad research program in statistical methods for modern large scale biomedical studies. Mitchell H. Gail is a Senior Investigator at the National Cancer Institute. His research includes modeling absolute risk of disease, intervention trials, and statistical methods for epidemiology. Alastair Scott was, at the time of his death, Professor Emeritus of Statistics, University of Auckland. He was a major contributor to using survey sampling methods for analyzing case-control data. Chris J. Wild is Professor of Statistics, University of Auckland. His research includes nonlinear regression and methods for fitting models to response-selective data.
Download or read book Introduction to Statistical Investigations written by Nathan Tintle and published by Wiley Global Education. This book was released on 2015-12-17 with total page 699 pages. Available in PDF, EPUB and Kindle. Book excerpt: Introduction to Statistical Investigations leads students to learn about the process of conducting statistical investigations from data collection, to exploring data, to statistical inference, to drawing appropriate conclusions. The text is designed for a one-semester introductory statistics course. It focuses on genuine research studies, active learning, and effective use of technology. Simulations and randomization tests introduce statistical inference, yielding a strong conceptual foundation that bridges students to theory-based inference approaches. Repetition allows students to see the logic and scope of inference. This implementation follows the GAISE recommendations endorsed by the American Statistical Association.
Download or read book Statistical Design for Research written by Leslie Kish and published by John Wiley & Sons. This book was released on 2005-02-25 with total page 267 pages. Available in PDF, EPUB and Kindle. Book excerpt: The Wiley Classics Library consists of selected books that have become recognized classics in their respective fields. With these new unabridged and inexpensive editions, Wiley hopes to extend the life of these important works by making them available to future generations of mathematicians and scientists. This title addresses those basic aspects of research design which are common to many related fields in the social sciences, health sciences, education, and market research. The work presents a unified approach to a common core of problems of statistical design that exists in all these fields, along with basic similarities in practical solutions. Describing many examples and analogies that are 'portable' from application field to application field, Statistical Design for Research deals with designs that are the primary basis of research studies, but are neglected in most statistical textbooks that tend to concentrate on statistical analysis. This text takes a broader, more general and philosophical view of the statistics for the more fundamental aspects of design than do the standard treatments of experimental design. Extensively illustrated and carefully organized into seven chapters and 44 sections, this book can be readily consulted by research workers or graduate students!
Download or read book Practical Statistics written by David Kremelberg and published by SAGE Publications. This book was released on 2010-03-18 with total page 529 pages. Available in PDF, EPUB and Kindle. Book excerpt: Making statistics—and statistical software—accessible and rewarding This book provides readers with step-by-step guidance on running a wide variety of statistical analyses in IBM® SPSS® Statistics, Stata, and other programs. Author David Kremelberg begins his user-friendly text by covering charts and graphs through regression, time-series analysis, and factor analysis. He provides a background of the method, then explains how to run these tests in IBM SPSS and Stata. He then progresses to more advanced kinds of statistics such as HLM and SEM, where he describes the tests and explains how to run these tests in their appropriate software including HLM and AMOS. This is an invaluable guide for upper-level undergraduate and graduate students across the social and behavioral sciences who need assistance in understanding the various statistical packages.
