Download or read book STAT2 written by Ann Cannon and published by Macmillan Higher Education. This book was released on 2018-11-05 with total page 0 pages. Available in PDF, EPUB and Kindle. Book excerpt: STAT2 introduces students to statistical modeling beyond what they have learned in a Stat 101 college course or an AP Statistics course. Building on basic concepts and methods learned in that course, STAT2 empowers students to analyze richer datasets that include more variables and address a broader range of research questions. Other than a working understanding of exponential and logarithmic functions, there are no prerequisites beyond successful completion of their first statistics course. To help all students make a smooth transition to this course, Chapter 0 reminds students of basic statistical terminology and also uses the familiar two-sample t-test as a way to illustrate the approach of specifying, estimating, and testing a statistical model. Using STAT2, students will: Go beyond their Stat 101 experience by learning to develop and apply models with both quantitative and categorical response variables, and with multiple explanatory variables. STAT2 Chapters are grouped into units that consider models based on the type of response and type of predictors. Discover that the practice of statistical modeling involves applying an interactive process. STAT2 employs a four-step process in all statistical modeling: Choose a form for the model, fit the model to the data, assess how well the model describes the data, and use the model to address the question of interest. Learn how to apply their developing judgment about statistical modeling. STAT2 introduces the idea of constructing statistical models at the very beginning, in a setting that students encountered in their Stat 101 course. This modeling focus continues throughout the course as students encounter new and increasingly more complicated scenarios. Analyze and draw conclusions from real data, which is crucial for preparing students to use statistical modeling in their professional lives. STAT2 incorporates real and rich data throughout the text. Using real data to address genuine research questions helps motivate students to study statistics. The richness stems not only from interesting contexts in a variety of disciplines, but also from the multivariable nature of most datasets.

Download or read book STAT 2 written by Ann R. Cannon and published by Macmillan Higher Education. This book was released on 2012-12-14 with total page 639 pages. Available in PDF, EPUB and Kindle. Book excerpt: STAT2 offers students who have taken AP Statistics or a typical introductory statistics college level course to learn more sophisticated concepts and the tools with which to apply them.

Download or read book Nuclear Trafficking written by Carl Feldherr and published by Academic Press. This book was released on 2012-12-02 with total page 385 pages. Available in PDF, EPUB and Kindle. Book excerpt: Nuclear Trafficking is a summary of the state of knowledge in nuclear trafficking, and is organized into five parts. The book begins by discussing the diffusion and signal-mediated transport through the pores. It then looks into the detailed accounts of pore structure and composition, nuclear localization signals, signal binding proteins, RNA efflux, and biochemical factors influencing nucleocytoplasmic exchange. This book will be very useful to those people new to this field of interest.

Download or read book Secondary Respiratory Infections in the Context of Acute and Chronic Pulmonary Diseases written by François Trottein and published by Frontiers Media SA. This book was released on 2020-01-23 with total page 161 pages. Available in PDF, EPUB and Kindle. Book excerpt:

Download or read book Cell Biology of Viral Infections written by Pierre-Yves Lozach and published by MDPI. This book was released on 2021-01-25 with total page 418 pages. Available in PDF, EPUB and Kindle. Book excerpt: Viruses exhibit an elegant simplicity as they are so basic, but so frightening. Although only a few are life threatening, they have substantial implications for human health and the economy, as exemplified by the ongoing coronavirus pandemic. Viruses are rather small infectious agents found in all types of life forms, from animals and plants to prokaryotes and archaebacteria. They are obligate intracellular parasites, and as such, subvert many molecular and cellular processes of the host cell to ensure their own replication, amplification, and subsequent spread. This Special Issue addresses the cell biology of viral infections based on a collection of original research articles, communications, opinions, and reviews on various aspects of virus–host cell interactions. Together, these articles not only provide a glance into the latest research on the cell biology of viral infections but also include novel technological developments.

Download or read book Stat2 written by Ann R. Cannon and published by . This book was released on 2012 with total page 519 pages. Available in PDF, EPUB and Kindle. Book excerpt:

Download or read book The Viral Evasion of Antiviral Innate Immunity written by Chunfu Zheng and published by Frontiers Media SA. This book was released on 2022-11-01 with total page 820 pages. Available in PDF, EPUB and Kindle. Book excerpt:

Download or read book Beyond Multiple Linear Regression written by Paul Roback and published by CRC Press. This book was released on 2021-01-14 with total page 436 pages. Available in PDF, EPUB and Kindle. Book excerpt: Beyond Multiple Linear Regression: Applied Generalized Linear Models and Multilevel Models in R is designed for undergraduate students who have successfully completed a multiple linear regression course, helping them develop an expanded modeling toolkit that includes non-normal responses and correlated structure. Even though there is no mathematical prerequisite, the authors still introduce fairly sophisticated topics such as likelihood theory, zero-inflated Poisson, and parametric bootstrapping in an intuitive and applied manner. The case studies and exercises feature real data and real research questions; thus, most of the data in the textbook comes from collaborative research conducted by the authors and their students, or from student projects. Every chapter features a variety of conceptual exercises, guided exercises, and open-ended exercises using real data. After working through this material, students will develop an expanded toolkit and a greater appreciation for the wider world of data and statistical modeling. A solutions manual for all exercises is available to qualified instructors at the book’s website at www.routledge.com, and data sets and Rmd files for all case studies and exercises are available at the authors’ GitHub repo (https://github.com/proback/BeyondMLR)

Download or read book The Cytokine Handbook Two Volume Set written by Angus W. Thomson and published by Elsevier. This book was released on 2003-04-22 with total page 1510 pages. Available in PDF, EPUB and Kindle. Book excerpt: The fourth edition of The Cytokine Handbook provides an encyclopedic coverage of the molecules that induce and regulate immune responses. Now expanded to two volumes, co-edited by Michael T Lotze, and written by over 120 international experts, the scope of the book has been broadened to include a major emphasis on the clinical applications of cytokines. The early chapters discuss individual cytokines, chemokines and receptors. Additional chapters discuss the clinical implications and applications of cytokines, including cytokine gene transfer, antisense therapy and assay systems. This book is essential for researchers and clinicians interested in cytokines, including anyone working in cancer biology, transplantation, infectious diseases, autoimmunity or bioinformatics. Key Features* Covers all main cytokines and chemokines * Written by experts* Up-to-date- includes detailed referencing accessing current, modern literature and reflects the newest findings from the human genome * The new edition has been thoroughly revised and extended (now 2 volumes) as compared to the last edition, including new co-editor (MTL), new authors, new hot topics and new chapters* Includes major emphasis on clinical applications* Extensively illustrated with tables and figures

Download or read book Cytokine Yearbook Volume 1 written by Sidney Pestka and published by Springer Science & Business Media. This book was released on 2012-12-06 with total page 100 pages. Available in PDF, EPUB and Kindle. Book excerpt: The justification for yearbooks is greater than ever as we approach the third millennium, overwhelmed with information. This first edition of the Cytokine Yearbook summarizes the latest advances in the revolutionary field of cytokine research. The work is not a comprehensive reference work, but covers a selection of current themes. The intention is to keep paying attention to current topics in the Yearbooks to come. The editors invited a number of distinguished colleagues, who are international experts in their specific fields, resulting in a high scientific level of the contributions. This Yearbook is required reading for every scientist and physician working in the field of cytokines.

Download or read book STATs and IRFs in Innate Immunity From Transcriptional Regulators to Therapeutic Targets written by Chien-Kuo Lee and published by Frontiers Media SA. This book was released on 2019-10-21 with total page 221 pages. Available in PDF, EPUB and Kindle. Book excerpt:

Download or read book Fundamental Immunology written by William E. Paul and published by Lippincott Williams & Wilkins. This book was released on 2008 with total page 1658 pages. Available in PDF, EPUB and Kindle. Book excerpt: Now thoroughly revised and updated, this comprehensive, up-to-date text is ideal for graduate students, post-doctoral fellows, microbiologists, infectious disease physicians, and any physician who treats diseases in which immunologic mechanisms play a role.

Download or read book Neutral Amino Acids Advances in Research and Application 2013 Edition written by and published by ScholarlyEditions. This book was released on 2013-06-21 with total page 384 pages. Available in PDF, EPUB and Kindle. Book excerpt: Neutral Amino Acids—Advances in Research and Application: 2013 Edition is a ScholarlyEditions™ book that delivers timely, authoritative, and comprehensive information about Threonine. The editors have built Neutral Amino Acids—Advances in Research and Application: 2013 Edition on the vast information databases of ScholarlyNews.™ You can expect the information about Threonine in this book to be deeper than what you can access anywhere else, as well as consistently reliable, authoritative, informed, and relevant. The content of Neutral Amino Acids—Advances in Research and Application: 2013 Edition has been produced by the world’s leading scientists, engineers, analysts, research institutions, and companies. All of the content is from peer-reviewed sources, and all of it is written, assembled, and edited by the editors at ScholarlyEditions™ and available exclusively from us. You now have a source you can cite with authority, confidence, and credibility. More information is available at http://www.ScholarlyEditions.com/.

Download or read book Cullin RING Ligases and Protein Neddylation written by Yi Sun and published by Springer Nature. This book was released on 2020-01-02 with total page 372 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book summarizes all the important aspects of CRLs (Cullin-RING E3 Ubiquitin Ligases), while providing details of mechanistic specifics that go beyond protein ubiquitination and neddylation. Ubiquitin ligases, including the CRLs, which are activated by neddylation, play an important role in diverse biological processes and are involved in various human diseases, particularly cancer. The book covers various topics, such as CRL structure, biology, genetics, its regulation by neddylation, its pivotal role in human disease, and its potential in drug discovery and targeted therapies. The book appeals to biochemists and biologists working in other fields, and, given the importance of CRLs in all aspects of cell biology and the great promise of targeting these complexes for therapy, is a valuable resource anyone interested in modern biology or medicine.

Download or read book Bioinformatics and Biomedical Engineering written by Ignacio Rojas and published by Springer. This book was released on 2019-04-30 with total page 605 pages. Available in PDF, EPUB and Kindle. Book excerpt: The two-volume set LNBI 11465 and LNBI 11466 constitutes the proceedings of the 7th International Work-Conference on Bioinformatics and Biomedical Engineering, IWBBIO 2019, held in Granada, Spain, in May 2019. The total of 97 papers presented in the proceedings, was carefully reviewed and selected from 301 submissions. The papers are organized in topical sections as follows: Part I: High-throughput genomics: bioinformatics tools and medical applications; omics data acquisition, processing, and analysis; bioinformatics approaches for analyzing cancer sequencing data; next generation sequencing and sequence analysis; structural bioinformatics and function; telemedicine for smart homes and remote monitoring; clustering and analysis of biological sequences with optimization algorithms; and computational approaches for drug repurposing and personalized medicine. Part II: Bioinformatics for healthcare and diseases; computational genomics/proteomics; computational systems for modelling biological processes; biomedical engineering; biomedical image analysis; and biomedicine and e-health.

Download or read book Real Time Programming written by Rudrapatna Shyamasundar and published by World Scientific. This book was released on 2010 with total page 262 pages. Available in PDF, EPUB and Kindle. Book excerpt: Pt. I. Real time systems - background. 1. Real time system characteristics. 1.1. Real-time and reactive programs. 2. Formal program development methodologies. 2.1. Requirement specification. 2.2. System specifications. 3. Characteristics of real-time languages. 3.1. Modelling features of real-time languages. 3.2. A look at classes of real-time languages. 4. Programming characteristics of reactive systems. 4.1. Execution of reactive programs. 4.2. Perfect synchrony hypothesis. 4.3. Multiform notion of time. 4.4. Logical concurrency and broadcast communication. 4.5. Determinism and causality -- pt. II. Synchronous languages. 5. ESTEREL language : structure. 5.1. Top level structure. 5.2. ESTEREL statements. 5.3. Illustrations of ESTEREL program behaviour. 5.4. Causality problems. 5.5. A historical perspective. 6. Program development in ESTEREL. 6.1. A simulation environment. 6.2. Verification environment. 7. Programming controllers in ESTEREL. 7.1. Auto controllers. 8. Asynchronous interaction in ESTEREL -- 9. Futurebus arbitration protocol : a case study. 9.1. Arbitration process. 9.2. Abstraction of the protocol. 9.3. Solution in ESTEREL -- 10. Semantics of ESTEREL. 10.1. Semantic structure. 10.2. Transition rules. 10.3. Illustrative examples. 10.4. Discussions. 10.5. Semantics of Esterel with exec -- pt. III. Other synchronous languages. 11. Synchronous language LUSTRE. 11.1. An overview of LUSTRE. 11.2. Flows and streams. 11.3. Equations, variables and expressions. 11.4. Program structure. 11.5. Arrays in LUSTRE. 11.6. Further examples. 12. Modelling Time-Triggered Protocol (TTP) in LUSTRE. 12.1. Time-triggered protocol. 12.2. Modelling TTP in LUSTRE. 13. Synchronous language ARGOS. 13.1. ARGOS constructs. 13.2. Illustrative example. 13.3. Discussions -- pt. IV. Verification of synchronous programs. 14. Verification of ESTEREL programs. 14.1. Transition system based verificationy of ESTEREL Programs. 14.2. ESTEREL transition system. 14.3. Temporal logic based verification. 14.4. Observer-based verification. 14.5. First order logic based verification. 15. Observer based verification of simple LUSTRE programs. 15.1. A simple auto controller. 15.2. A complex controller. 15.3. A cruise controller. 15.4. A train controller. 15.5. A mine pump controller -- pt. V. Integration of synchrony and asynchrony. 16. Communicating reactive processes. 16.1. An overview of CRP. 16.2. Communicating reactive processes : structure. 16.3. Behavioural semantics of CRP. 16.4. An illustrative example : banker teller machine. 16.5. Implementation of CRP. 17. Semantics of communicating reactive processes. 17.1. A brief overview of CSP. 17.2. Translation of CSP to CRP. 17.3. Cooperation of CRP nodes. 17.4. Ready-trace semantics of CRP. 17.5. Ready-trace semantics of CSP. 17.6. Extracting CSP ready-trace semantics from CRP semantics. 17.7. Correctness of the translation. 17.8. Translation into MEIJE process calculus. 18. Communicating reactive state machines. 18.1. CRSM constructs. 18.2. Semantics of CRSM. 19. Multiclock ESTEREL. 19.1. Need for a multiclock synchronous paradigm. 19.2. Informal introduction. 19.3. Formal semantics. 19.4. Embedding CRP. 19.5. Modelling a VHDL subset. 19.6. Discussion. 20. Modelling real-time systems in ESTEREL. 20.1. Interpretation of a global clock in terms of exec. 20.2. Modelling real-time requirements. 21. Putting it together

Download or read book Build an Orchestrator in Go From Scratch written by Tim Boring and published by Simon and Schuster. This book was released on 2024-04-23 with total page 286 pages. Available in PDF, EPUB and Kindle. Book excerpt: Understand Kubernetes and other orchestration systems deeply by building your own using Go and the Docker API. In Build an Orchestrator in Go (From Scratch) you will learn how to: Identify the components that make up any orchestration system Schedule containers on to worker nodes Start and stop containers using the Docker API Manage a cluster of worker nodes using a simple API Work with algorithms taken from cutting-edge Google Borg research papers Demystify orchestration systems like Kubernetes and Nomad Orchestration systems like Kubernetes coordinate other software subsystems and services to create a complete organized system. Although orchestration tools have a reputation for complexity, they’re designed around few important patterns that apply across many aspects of software development. Build an Orchestrator in Go (From Scratch) reveals the inner workings of orchestration frameworks by guiding you as you design and implement your own using the Go SDK. As you create your own orchestration framework, you’ll improve your understanding of Kubernetes and its role in distributed system design. You’ll also build the skills required to design custom orchestration solutions for those times when an out-of-the-box solution isn’t a good fit. Purchase of the print book includes a free eBook in PDF, Kindle, and ePub formats from Manning Publications. About the technology Orchestration systems provide the management framework for software and infrastructure that’s distributed across multiple machines and services. By managing the many individual components and containers in a large application, they ensure web apps are resilient and reliable, automatically switching between resources in response to crashes and outages. A properly designed orchestration system can seamlessly scale to handle traffic loads, and reduce time-consuming manual work for sysadmin and site reliability engineers. About the book Build an Orchestrator in Go (From Scratch) teaches you to implement an orchestrator from scratch. You’ll discover the components that make up all orchestration systems, and use the Docker API and Go SDK to build layers of functionality from tasks, to workers, to the manager. Learn how to save on costs by maximising the usage of a cluster, or spread tasks among workers to avoid overload and downtime. Once you’ve built your working system, you’ll even implement a command line user interface to easily manage your orchestrator. About the reader For software engineers, operations professionals, and SREs who are familiar with Docker and the basics of Go. About the author Tim Boring is a staff engineer at Golioth. He has twenty years of experience in technology organizations ranging from small business to global enterprises. His career spans roles in technical support to site reliability and software engineering. Tim is most interested in the design of software systems and distributed systems in particular.