Download or read book Standards for Ocular Toxicology and Inflammation written by Brian C. Gilger and published by Springer. This book was released on 2018-08-31 with total page 212 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book is an international effort to standardize the language, terms, and methods used in ocular toxicology.With over 300 color illustrations this consensus volume provides standards and harmonization for procedures, terminology, and scoring schemes for ocular toxicology. it is essential for industry, pharmaceutical companies, and governmental agencies to help improve the drug development process and to reduce and refine the use of animals in research. Standards for Ocular Toxicology and Inflammation is endorsed by the American College of Veterinary Ophthalmologists.
Download or read book Advances in Ocular Toxicology written by Keith Green and published by Springer Science & Business Media. This book was released on 2012-12-06 with total page 282 pages. Available in PDF, EPUB and Kindle. Book excerpt: This volume represents the proceedings of the Fifth Congress of the International Society of Ocular Toxicology (ISOT), which was held at the Grove Park Inn and Resort in Asheville, North Carolina, October 13-17, 1996. We are delighted to present this volume to the ophthalmic community, especially those with a significant interest in ocular toxicol ogy. The Fifth Congress was developed around themes relating to ocular drug metabolism, the ocular pathophysiological effects of nitric oxide, government issues relating to the use of alternative methods for toxicity testing, and a workshop that encompassed comparisons of both in vitro versus in vivo models as well as different animal models. The outcome of this congress, embodied in this volume, is a contribution to the methodologies currently employed or under development and to various drug or physical effects on different ocular tissues. While the focus of this proceedings is on ocular effects of drugs or other materials, many of the contributions deal with topics that have a much broader interest. The workshop concerning the use of different model systems and the choice of the best animal model for drug testing covers a wide range of interests that ex tends far beyond specific ocular effects. This is especially true in the area of alternative methods and in the choice of the best animal model for examination of different disease entities.
Download or read book Ocular Toxicology written by Ingo Weisse and published by Springer Science & Business Media. This book was released on 1995 with total page 398 pages. Available in PDF, EPUB and Kindle. Book excerpt: Proceedings of the Fourth Congress of the International Society of Ocular Toxicology (ISOT), held October, 1994 in Annecy, France. This congress was designed primarily to facilitate and update the knowledge in ocular electrophysiology and ocular pharmacokinetics, in both the clinical and preclinical
Download or read book Assessing Ocular Toxicology in Laboratory Animals written by Springer and published by . This book was released on 2012-12-01 with total page 336 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Download or read book Immune Modulation and Anti Inflammatory Therapy in Ocular Disorders written by Uwe Pleyer and published by . This book was released on 2014-06-30 with total page 260 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Download or read book Immune Modulation and Anti Inflammatory Therapy in Ocular Disorders written by Uwe Pleyer and published by Springer. This book was released on 2016-08-23 with total page 0 pages. Available in PDF, EPUB and Kindle. Book excerpt: These guidelines, compiled by a panel of clinicians and scientists with a high level of expertise, aim to provide readers with the most up-to-date and comprehensive instructions on the treatment and prevention of ocular inflammation. All of the recommendations are explicitly linked to supporting evidence and graded according to the strength of that evidence and the editors have made every effort to ensure that chapters are of a consistently high methodological quality. The guidelines for each treatment include dose and the frequency and mode of delivery. Significant side-effects of treatment are identified and distinguished from those of the disease in question. Suggestions are presented for the prevention both of the disease itself and of the treatment-related complications. In addition, likely future directions in treatment and prevention are identified. These guidelines will be of great practical value for all clinicians and clinical scientists with an interest in the subject.
Download or read book Haschek and Rousseaux s Handbook of Toxicologic Pathology Volume 4 Toxicologic Pathology of Organ Systems written by Wanda M. Haschek and published by Elsevier. This book was released on 2024-05-02 with total page 910 pages. Available in PDF, EPUB and Kindle. Book excerpt: Haschek and Rousseaux's Handbook of Toxicologic Pathology, Volume Four: Toxicologic Pathology of Organ Systems is a key reference on the integration of structure and functional changes in tissues associated with the response to pharmaceuticals, chemicals and biologics. Organ systems covered include cardiac, vascular and skeletal muscle systems and the endocrine, respiratory, reproductive, digestive and nervous systems. Completely revised with a new olfactory chapter, this new release is an essential part of the most authoritative reference on toxicologic pathology for pathologists, toxicologists, research scientists and regulators studying and making decisions on drugs, biologics, medical devices, and other chemicals, including agrochemicals and environmental contaminants. Presents updated chapters on systems toxicologic pathology, including new chapter on olfactory Offers high-quality and trusted content in a multi-contributed work written by leading international authorities in all areas of toxicologic pathology Features hundreds of full-color images in both the print and electronic versions to highlight difficult concepts with clear illustrations
Download or read book Proceedings of the Congress of the International Society of Ocular Toxicology written by International Society of Ocular Toxicology and published by . This book was released on 1990 with total page 588 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Download or read book A Comprehensive Guide to Toxicology in Nonclinical Drug Development written by Ali S. Faqi and published by Elsevier. This book was released on 2024-02-11 with total page 1074 pages. Available in PDF, EPUB and Kindle. Book excerpt: A Comprehensive Guide to Toxicology in Nonclinical Drug Development, Third Edition is a valuable reference providing a complete understanding of all aspects of nonclinical toxicology in pharmaceutical research. This updated edition has been expanded and re-developed covering a wide-range of toxicological issues in small molecules and biologics. Topics include ADME in drug discovery, pharmacokinetics, toxicokinetics, formulations, and genetic toxicology testing. The book has been thoroughly updated throughout to reflect the latest scientific advances and includes new information on antiviral drugs, anti-diabetic drugs, immunotherapy, and a discussion on post-pandemic drug development challenges and opportunities. This is an essential and practical resource for all toxicologists involved in nonclinical testing in industry, academic, and regulatory settings. Provides updated, unique content not covered in one comprehensive resource, including chapters on stem cells, antiviral drugs, anti-diabetic drugs, and immunotherapy Includes the latest international guidelines for nonclinical toxicology in both small and large molecules Incorporates practical examples in order to illustrate day-to-day activities and expectations associated with working in nonclinical toxicology
Download or read book Dermal and Ocular Toxicology written by David W. Hobson and published by CRC Press. This book was released on 2020-11-25 with total page 664 pages. Available in PDF, EPUB and Kindle. Book excerpt: Dermal and Ocular Toxicology: Fundamentals and Methods is a procedurally-oriented volume of detailed methods and practical examples discussing the dermal and ocular aspects of toxicology. The book is divided into a dermal section and an ocular section. Each section begins with a chapter on the anatomy and physiology of each organ system and then progresses to more specialized chapters discussing such topics as the toxicological pathology of each system, state-of-the-art in vitro and in vivo evaluatory procedures, statistical considerations for test design and data interpretation, and the utilization of test findings. Test methods are provided for acute dermal exposure effects, dermal hypersensitivity and photoallergy assessment, dermal and ocular 0.pharmacokinetics, skin flap and skin grafting techniques, and in vitro alternative methods. This book can be used as an instructional text or as a sourcebook for practicing toxicologists, pharmacologists, industrial hygienists, occupational health professionals, and graduate students.
Download or read book Drug Induced Ocular Side Effects Clinical Ocular Toxicology E Book written by Frederick T. Fraunfelder and published by Elsevier Health Sciences. This book was released on 2014-09-19 with total page 425 pages. Available in PDF, EPUB and Kindle. Book excerpt: Ideal for ophthalmologists, optometrists and busy clinicians, Drug-Induced Ocular Side Effects provides the clinically relevant information you need to diagnose and manage chemical and drug-related ocular problems. An easily accessible format, meticulous revisions and comprehensive coverage of all drugs’ generic and trade names, primary uses, ocular and systemic side effects, and clinical significance make this best-selling resource the ideal reference for quick, on-the-spot consultation. Consult this title on your favorite e-reader, conduct rapid searches, and adjust font sizes for optimal readability. Manage any challenge in ocular toxicology with extensive coverage of principles of therapy; ocular drug delivery; methods to evaluate drug-induced visual side effects; and the role of electrophysiology and psychophysics. Benefit from the masterful guidance and global perspective of world authorities in the field who provide need-to-know information on all aspects of ocular toxicology—all in one concise reference. Confer with the WHO classification system to determine whether a particular side effect is certain, probable, or likely to occur. Zero in on the key information you need to know with highly templated, concise chapters. Apply the latest knowledge and treatments for newly recognized Adverse Drug Reactions (ADR). Identify which ADR’s are clinically relevant and what to do about them. Experience clinical scenarios with vivid clarity through a wealth of new and updated clinical photographs that provide unmatched, visual diagnostic guidance. Recognize and avoid drug-induced ocular side effects with data from the National Registry of Drug Induced Ocular Side-Effects (Casey Eye Institute, Portland, OR) and the World Health Organization (Uppsala, Sweden). Stay up to date and provide state-of-the-art care with the latest information on approved medications. Access the complete contents online at Expert Consult.
Download or read book Crises in Oil Gas and Petrochemical Industries written by Mohammad Reza Rahimpour and published by Elsevier. This book was released on 2023-07-13 with total page 494 pages. Available in PDF, EPUB and Kindle. Book excerpt: Crises in Oil, Gas and Petrochemical Industries: Disasters and Environmental Challenges provides an overview of both natural and manmade disasters occurring in oil, gas and petrochemical industries while also covering special solutions based on their types. This volume includes the effects of natural disasters such as earthquakes, floods and hurricanes as well as manmade incidents including fire events, explosions and the release of dust and toxic substances on various related units and plants. In addition, the long-term side effects on both humans and the environment resulted from these industries are presented. Problems such as releasing wastes and venting gases into the environment and challenges from overusing the natural resources and producing noise pollutants are also discussed in detail. Introduces the effects of natural disasters on the oil, gas and petrochemical industries Describes the effect of manmade disasters on oil, gas and petrochemical industries Discusses the long-term side effects of oil, gas and petrochemical units on humans and the environments
Download or read book Toxicology Research Projects Directory written by and published by . This book was released on 1980-04 with total page 624 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Download or read book Ocular Pharmacology and Toxicology written by Brian C. Gilger and published by . This book was released on 2014 with total page 0 pages. Available in PDF, EPUB and Kindle. Book excerpt: "Covering ocular pharmacokinetics, pharmacodynamics, and toxicology, Ocular Pharmacology and Toxicology provides ophthalmologists, toxicologists, and pharmacologists with both an introduction to the proper methods for ocular pharmacology and toxicology as well as providing practical methodologies for conducting ocular studies. Expert authors have contributed detailed chapters on study design, analysis, and routes to regulatory approval for various types and routes of ophthalmic drugs. As a volume in the Methods in Pharmacology and Toxicology series, chapters feature the kind of in-depth specifics and implementation advice to ensure successful results. Practical and authoritative, Ocular Pharmacology and Toxicology serves as an ideal basis of training in the proper design and conduct of essential studies to accurately determine pharmacokinetics and ocular toxicity from the systemic, topical, periocular, or intraocular administration of drugs or compounds, from the use of ocular medical devices and from ocular surgical procedures."--Publisher's description.
Download or read book The impact of clinical and environmental toxicological exposures and eye health written by Anat Galor and published by Frontiers Media SA. This book was released on 2024-06-26 with total page 127 pages. Available in PDF, EPUB and Kindle. Book excerpt: The eye is often times referred to as the ”window to the soul”. This is relevant to the practice of medicine as many systemic disorders can present with eye manifestations that can be detected by routine ophthalmic examination and the findings used to help physicians in the diagnosis and management of an individual patient. Conditions with potential eye manifestations include infections, metabolic disorders, auto-immune diseases, and exposure, to name a few. With respect to the latter, various toxicological exposures, whether environmental or clinical, can manifest with eye findings. Some associations are well characterized, such as crystalline retinal deposits that can occur with prolonged tamoxifen use, while others are less well described or understood.
Download or read book Primary Care E Book written by Terry Mahan Buttaro and published by Elsevier Health Sciences. This book was released on 2024-03-02 with total page 1618 pages. Available in PDF, EPUB and Kindle. Book excerpt: There’s no better preparation for Nurse Practitioners and other adult primary care practitioners! Buttaro’s Primary Care: Interprofessional Collaborative Practice, 7th Edition provides the concise yet thorough information that you need in today's fast-paced, interprofessional, collaborative environment. With authorship reflecting both academic and clinical expertise, this comprehensive, evidence-based primary care text/reference shows you how to deliver effective, truly interdisciplinary health care. It covers every major adult disorder seen in the outpatient office setting and features a unique interprofessional collaborative approach with referral and “Red Flag” highlights and more. New to this edition are chapters on health equity, public health preparedness, endocannabinoids, and self-care. Comprehensive, evidence-based, accurate, and current content provides a complete foundation in the primary care of adults for NP students, including students in Doctor of Nursing Practice (DNP) programs, and reflects the latest research and national and international guidelines. UNIQUE! Interprofessional collaborative approach equips you for interprofessional collaborative practice in the contemporary healthcare environment. Consistent chapter format and features reflect the systematic approach used in adult primary care practice to promote improved clinical judgment skills, facilitate learning, and foster quick clinical reference. UNIQUE! Referral/Consultation highlights indicate when the NP should collaborate with, or refer to, other providers. UNIQUE! Emergency Referral highlights indicate when the NP should refer the patient for urgent/emergent care. UNIQUE! Red Flag highlights indicate issues not to be missed. UNIQUE! Initial Diagnostics boxes provide quick reference to key decision-making content.
Download or read book WHO Guidelines for Indoor Air Quality written by and published by World Health Organization. This book was released on 2010 with total page 488 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book presents WHO guidelines for the protection of public health from risks due to a number of chemicals commonly present in indoor air. The substances considered in this review, i.e. benzene, carbon monoxide, formaldehyde, naphthalene, nitrogen dioxide, polycyclic aromatic hydrocarbons (especially benzo[a]pyrene), radon, trichloroethylene and tetrachloroethylene, have indoor sources, are known in respect of their hazardousness to health and are often found indoors in concentrations of health concern. The guidelines are targeted at public health professionals involved in preventing health risks of environmental exposures, as well as specialists and authorities involved in the design and use of buildings, indoor materials and products. They provide a scientific basis for legally enforceable standards.
