Download or read book Spotlight on the Relationship between Sepsis and Infection from Mechanisms to Therapy written by Alessandro Russo and published by Frontiers Media SA. This book was released on 2021-09-29 with total page 292 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Download or read book Handbook of Sepsis written by W. Joost Wiersinga and published by Springer. This book was released on 2018-04-13 with total page 267 pages. Available in PDF, EPUB and Kindle. Book excerpt: This practically oriented book provides an up-to-date overview of all significant aspects of the pathogenesis of sepsis and its management, including within the intensive care unit. Readers will find information on the involvement of the coagulation and endocrine systems during sepsis and on the use of biomarkers to diagnose sepsis and allow early intervention. International clinical practice guidelines for the management of sepsis are presented, and individual chapters focus on aspects such as fluid resuscitation, vasopressor therapy, response to multiorgan failure, antimicrobial therapy, and adjunctive immunotherapy. The closing section looks forward to the coming decade, discussing novel trial designs, sepsis in low- and middle-income countries, and emerging management approaches. The book is internatio nal in scope, with contributions from leading experts worldwide. It will be of value to residents and professionals/practitioners in the fields of infectious diseases and internal medicine, as well as to GPs and medical students.
Download or read book Infectious Diseases written by and published by . This book was released on 1977 with total page 332 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Download or read book Bugs as Drugs written by Robert A. Britton and published by John Wiley & Sons. This book was released on 2020-07-02 with total page 514 pages. Available in PDF, EPUB and Kindle. Book excerpt: Examining the enormous potential of microbiome manipulation to improve health Associations between the composition of the intestinal microbiome and many human diseases, including inflammatory bowel disease, cardiovascular disease, metabolic disorders, and cancer, have been elegantly described in the past decade. Now, whole-genome sequencing, bioinformatics, and precision gene-editing techniques are being combined with centuries-old therapies, such as fecal microbiota transplantation, to translate current research into new diagnostics and therapeutics to treat complex diseases. Bugs as Drugs provides a much-needed overview of microbes in therapies and will serve as an excellent resource for scientists and clinicians as they carry out research and clinical studies on investigating the roles the microbiota plays in health and disease. In Bugs as Drugs, editors Robert A. Britton and Patrice D. Cani have assembled a fascinating collection of reviews that chart the history, current efforts, and future prospects of using microorganisms to fight disease and improve health. Sections cover traditional uses of probiotics, next-generation microbial therapeutics, controlling infectious diseases, and indirect strategies for manipulating the host microbiome. Topics presented include: How well-established probiotics support and improve host health by improving the composition of the intestinal microbiota of the host and by modulating the host immune response. The use of gene editing and recombinant DNA techniques to create tailored probiotics and to characterize next-generation beneficial microbes. For example, engineering that improves the anti-inflammatory profile of probiotics can reduce the number of colonic polyps formed, and lactobacilli can be transformed into targeted delivery systems carrying therapeutic proteins or bioengineered bacteriophage. The association of specific microbiota composition with colorectal cancer, liver diseases, osteoporosis, and inflammatory bowel disease. The gut microbiota has been proposed to serve as an organ involved in regulation of inflammation, immune function, and energy homeostasis. Fecal microbiota transplantation as a promising treatment for numerous diseases beyond C. difficile infection. Practical considerations for using fecal microbiota transplantation are provided, while it is acknowledged that more high-quality evidence is needed to ascertain the importance of strain specificity in positive treatment outcomes. Because systems biology approaches and synthetic engineering of microbes are now high-throughput and cost-effective, a much wider range of therapeutic possibilities can be explored and vetted.
Download or read book Endotoxin in Health and Disease written by Helmut Brade and published by CRC Press. This book was released on 2020-10-28 with total page 968 pages. Available in PDF, EPUB and Kindle. Book excerpt: Offering a basis for further research into the interactions of hosts and pathogens, this work gathers up-to-date findings, and details basic structures, functions and immunology. It provides descriptions of a variety of experimental endotoxin neutralizing agents, as well as a guide to clinical research initiatives and the latest treatments.
Download or read book Hemodynamic Monitoring written by Michael R. Pinsky and published by Springer. This book was released on 2019-02-21 with total page 476 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book, part of the European Society of Intensive Care Medicine textbook series, teaches readers how to use hemodynamic monitoring, an essential skill for today’s intensivists. It offers a valuable guide for beginners, as well as for experienced intensivists who want to hone their skills, helping both groups detect an inadequacy of perfusion and make the right choices to achieve the main goal of hemodynamic monitoring in the critically ill, i.e., to correctly assess the cardiovascular system and its response to tissue oxygen demands. The book is divided into distinguished sections: from physiology to pathophysiology; clinical assessment and measurements; and clinical practice achievements including techniques, the basic goals in clinical practice as well as the more appropriate hemodynamic therapy to be applied in different conditions. All chapters use a learning-oriented style, with practical examples, key points and take home messages, helping readers quickly absorb the content and, at the same time, apply what they have learned in the clinical setting. The European Society of Intensive Care Medicine has developed the Lessons from the ICU series with the vision of providing focused and state-of-the-art overviews of central topics in Intensive Care and optimal resources for clinicians working in Intensive Care.
Download or read book Annual Update in Intensive Care and Emergency Medicine 2021 written by Jean-Louis Vincent and published by Springer Nature. This book was released on 2021-09-03 with total page 301 pages. Available in PDF, EPUB and Kindle. Book excerpt: The Annual Update compiles reviews of the most recent developments in experimental and clinical intensive care and emergency medicine research and practice in one comprehensive book. The chapters are written by well recognized experts in these fields. The book is addressed to everyone involved in internal medicine, anesthesia, surgery, pediatrics, intensive care and emergency medicine.
Download or read book Hurdles for Phage Therapy PT to Become a Reality written by Harald Brüssow and published by MDPI. This book was released on 2019-08-20 with total page 484 pages. Available in PDF, EPUB and Kindle. Book excerpt: Alternative treatment modes for antibiotic-resistant bacterial pathogens have become a public health priority. Bacteriophages are bacterial viruses that infect and lyse bacterial cells. Since bacteriophages are frequently bacterial host species-specific and can often also infect antibiotic-resistant bacterial cells, they could represent ideal antimicrobials for fighting the antibiotic resistance crisis. The medical use of bacteriophages has become known as phage therapy. It is widely used in Russia, where phage cocktails are sold in pharmacies as an over-the-counter drug. However, no phage product has been registered for medical purposes outside of the former Soviet Union. The current Special Issue of Viruses contains a collection of papers from opinion leaders in the field who explore hurdles to the introduction of phage therapy in western countries. The articles cover diverse topics ranging from patent to regulatory issues, the targeting of suitable bacterial infections, and the selection and characterization of safe and efficient phage cocktails. Phage resistance is discussed, and gaps in our knowledge of phage–bacterium interactions in the mammalian body are revealed, while other articles explore the use of phages in food production and processing.
Download or read book Index Medicus written by and published by . This book was released on 2004 with total page 1930 pages. Available in PDF, EPUB and Kindle. Book excerpt: Vols. for 1963- include as pt. 2 of the Jan. issue: Medical subject headings.
Download or read book Early onset Neonatal Sepsis written by and published by . This book was released on 2010 with total page 0 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Download or read book Newborn Surgery 3E written by Prem Puri and published by CRC Press. This book was released on 2011-11-25 with total page 1044 pages. Available in PDF, EPUB and Kindle. Book excerpt: Newborn Surgery, Third Edition provides a comprehensive compendium of the pathophysiology, investigation and management of neonatal disorders. Areas covered include in this new edition include: Preoperative assessment Anesthesia Postoperative management Nutrition Ethical considerations in newborn surgery Head, neck, and chest surgery Esophagus and gastrointestinal tract surgery Liver and biliary tract surgery Anterior abdominal wall defects Tumors Spina bifida and hydrocephalus Genitourinary issues Long-term outcomes in newborn surgery With its uniquely comprehensive coverage of neonatal surgical specialties, this book is the first stop for anyone looking to supplement their knowledge in this broad and increasingly disparate field, including pediatric surgeons, general surgeons with pediatric practice, neonatologists, pediatricians, and pediatric radiologists.
Download or read book Rickettsial Diseases written by Didier Raoult and published by CRC Press. This book was released on 2007-04-26 with total page 400 pages. Available in PDF, EPUB and Kindle. Book excerpt: The only available reference to comprehensively discuss the common and unusual types of rickettsiosis in over twenty years, this book will offer the reader a full review on the bacteriology, transmission, and pathophysiology of these conditions. Written from experts in the field from Europe, USA, Africa, and Asia, specialists analyze specific patho
Download or read book Endometriosis written by Juan A Garcia-Velasco and published by Boydell & Brewer Ltd. This book was released on 2010-09-17 with total page 360 pages. Available in PDF, EPUB and Kindle. Book excerpt: Endometriosis is a condition that effects 10% to 15% of women of reproductive age and in its more advanced stages it may be an indicator of infertility. This unique book reviews the whole topic of Endometriosis starting from a review of the epidemiological evidence through the sociology of the disease to diagnosis, medical and surgical treatments, management and a discussion of new medical options and future trends in the disease area. It covers pathogenesis, current and future diagnostic methods, therapeutic alternatives; and discusses fertility preservation, cancer possibilities, and quality of life in patients. The book also examines new medical treatments for the condition including Statins, Aromatase Inhibitors and Antiagiogenic Agents and reviews new delivery technologies for classical drugs and provides a synopsis of the new drug pipeline for the condition.
Download or read book Critical Needs and Gaps in Understanding Prevention Amelioration and Resolution of Lyme and Other Tick Borne Diseases written by Institute of Medicine and published by National Academies Press. This book was released on 2011-07-01 with total page 560 pages. Available in PDF, EPUB and Kindle. Book excerpt: A single tick bite can have debilitating consequences. Lyme disease is the most common disease carried by ticks in the United States, and the number of those afflicted is growing steadily. If left untreated, the diseases carried by ticks-known as tick-borne diseases-can cause severe pain, fatigue, neurological problems, and other serious health problems. The Institute of Medicine held a workshop October 11-12, 2010, to examine the state of the science in Lyme disease and other tick-borne diseases.
Download or read book The Neonatal Immune System A Unique Host Microbial Interface written by Joseph M. Bliss and published by Frontiers Media SA. This book was released on 2018-01-25 with total page 175 pages. Available in PDF, EPUB and Kindle. Book excerpt: Emerging from the protective environment of the uterus, the newborn is exposed to a myriad of microbes, and quickly establishes a complex microbiome that shapes the infant’s biology in ways that are only now beginning to come to light. Among these exposures are a number of potential pathogens. The host responses to these pathogens in the neonatal period are unique, reflecting a developing immune system even with delivery at term. Preterm infants are delivered at a time when host defense mechanisms are even less developed and therefore face additional risk. As such, the organisms that cause disease in this period are different from the pathogens that are common in other age groups, or the disease they cause manifests in more severe fashion. Developmental alterations in both innate and adaptive immune responses in neonates have been documented among many cell types and pathways over the last several decades. Contemporary insights into the human immune system and methodologies that allow an “omics” approach to these questions have continued to provide new information regarding the mechanisms that underlie the human neonate as an “immunocompromised host.” This Research Topic highlights studies related to this unique host-pathogen interface. Contributions include those related to the innate or adaptive immune system of neonates, their response to microbial colonization or infection, and/or the pathogenesis of microbes causing disease in neonates.
Download or read book Toxicity Bibliography written by and published by . This book was released on 1973-10 with total page 850 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Download or read book Cumulated Index Medicus written by and published by . This book was released on 2000 with total page 1836 pages. Available in PDF, EPUB and Kindle. Book excerpt:
