Download or read book Spin Labeling written by Lawrence J. Berliner and published by Springer Science & Business Media. This book was released on 2006-01-14 with total page 435 pages. Available in PDF, EPUB and Kindle. Book excerpt: We present here the second issue devoted entirely to the spin-labeling technique as part of Biological Magnetic Resonance. Volume 14 commemorates a modifi- tion in our editorial policy with the retirement of my esteemed coeditor, Jacques Reuben. From thisjuncture into the future, each issue will focus on some special topic in magnetic resonance. Each volume will be organized in most cases by guest editors, for example forthcoming issues will address the following topics: in vivo magnetic resonance (P. Robitaille and L. J. Berliner, eds. ) Modern techniques in proton NMR ofproteins (R. Krishna and L. J. Berliner, eds. ) Instrumental techniques of EPR (C. Bender and L. J. Berliner, eds. ) Thecurrent volume, Spin Labeling: The NextMillennium, presents an excellent collection of techniques and applications that evolved during the past decade since the last volume, volume 8 (1989). Someobvious omissions, such as multiquantum EPR and very high-frequency FT-ESR were unfortunately not possible for this volume. Perhaps they will appear in Spin Labeling: 2001. Lastly it is a pleasure to honor two scientists whose contributions were both pioneering and pivotal to the spin label technique: Professor Eduard G. Rozantsev (Moscow), whose synthetic feats in nitroxyl chemistry set the broad stage for a versatile catalog of labels; and Professor Harden M. McConnell, last year's Int- national ESR (EPR) Society Gold Medalist, who conceived and developed the spin label technique to address many biological problems (proteins, enzymes, m- branes, cells, immune response, etc. ). Lawrence J.

Download or read book Distance Measurements in Biological Systems by EPR written by Lawrence J. Berliner and published by Springer Science & Business Media. This book was released on 2006-02-20 with total page 622 pages. Available in PDF, EPUB and Kindle. Book excerpt: Distance measurements in biological systems by EPR The foundation for understanding function and dynamics of biological systems is knowledge of their structure. Many experimental methodologies are used for determination of structure, each with special utility. Volumes in this series on Biological Magnetic Resonance emphasize the methods that involve magnetic resonance. This volume seeks to provide a critical evaluation of EPR methods for determining the distances between two unpaired electrons. The editors invited the authors to make this a very practical book, with specific numerical examples of how experimental data is worked up to produce a distance estimate, and realistic assessments of uncertainties and of the range of applicability, along with examples of the power of the technique to answer biological problems. The first chapter is an overview, by two of the editors, of EPR methods to determine distances, with a focus on the range of applicability. The next chapter, also by the Batons, reviews what is known about electron spin relaxation times that are needed in estimating distances between spins or in selecting appropriate temperatures for particular experiments. Albert Beth and Eric Hustedt describe the information about spin-spin interaction that one can obtain by simulating CW EPR line shapes of nitroxyl radicals. The information in fluid solution CW EPR spectra of dual-spin labeled proteins is illustrated by Hassane Mchaourab and Eduardo Perozo.

Download or read book Current Catalog written by National Library of Medicine (U.S.) and published by . This book was released on 1979 with total page pages. Available in PDF, EPUB and Kindle. Book excerpt: First multi-year cumulation covers six years: 1965-70.

Download or read book Biological Magnetic Resonance written by Lawrence J. Berliner and published by Springer Science & Business Media. This book was released on 2013-11-11 with total page 356 pages. Available in PDF, EPUB and Kindle. Book excerpt: We take great pleasure in presenting Vol. IV of Biological Magnetic Resonance, a series that continues to give us pride. In this volume, we are pleased to have our first chapter on the applications of ESR to problems in medicine, written by Butterfield. Armitage and Otvos describe their extensive Cd-l13 NMR study in a chapter that should delight the spectroscopists as well as the biochemists, since the systems investigated have not yet been modeled. Kaptein presents an eloquent exposition of the principles and applications to biological systems of the photo-CIDNP technique, to which he has made pioneering contributions. Perkins tells everything one always wanted to know about the applications of ring current calculations in structural studies of biological macromolecules. Our philosophy has been, and continues to be, to present topics of current interest by authors who are active in their field, while maintaining the inter national flavor of the series. Ideally, the coverage of each topic should approach that found both in a textbook and in a reference book, rather than being a mere literature review. We are grateful to the authors for their cooperation in this respect. We continue to solicit the comments and suggestions of our readers and our colleagues, and thank those who have already responded, including the reviewers in the periodicals. Lawrence J. Berliner Jacques Reuben ix Contents Chapter 1 Spin Labeling in Disease D. Allan Butterfield 1. Introduction ...................................... . 2. Membrane Structure . . . . . . . . . . . . . . . . . . . . . . . . . . 2 . . . . . . . 2.1. General Principles. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 2 2.2. The Erythrocyte Membrane. . . . . . . . . . . . . . . . . . . 4 . . . . .

Download or read book Biomedical EPR Part B Methodology Instrumentation and Dynamics written by Sandra S. Eaton and published by Springer Science & Business Media. This book was released on 2004 with total page 504 pages. Available in PDF, EPUB and Kindle. Book excerpt: Biomedical EPR – Part A focuses on applications of EPR spectroscopy in the areas of free radicals, metals, medicine, and physiology. The book celebrates the 70th birthday of Prof. James S. Hyde, Medical College of Wisconsin, and his contributions to this field. Chapters are written to provide introductory material for new-comers to the field which lead into up-to-date reviews that provide perspective on the wide range of questions that can be addressed by EPR. Key Features:Free Radicals in Medicine Radicals in vivo and in Model Systems, and their Study by Spin Trapping In vivo EPR, including Oximetry and Imaging Time Domain EPR at Radio Frequencies EPR of Copper Complexes: Motion and Frequency Dependence Time Domain EPR and Electron Spin Echo Envelope Modulation About the Editors: Prof. Sandra S. Eaton is John Evans Professor in the Department of Chemistry and Biochemistry at the University of Denver. Her research interests include distance measurements in proteins, EPR of metal ions in biological systems, electron spin relaxation times, and EPR instrumentation. The Eatons co-organize an annual EPR Symposium in Denver. Prof. Gareth R. Eaton is John Evans Professor in the Department of Chemistry and Biochemistry at the University of Denver. His research interests include EPR instrumentation, distance measurements in proteins, EPR of metal ions in biological systems, and electron spin relaxation times. Dr. Lawrence J. Berliner is currently Professor and Chair of the Department of Chemistry and Biochemistry at the University of Denver after retiring from Ohio State University, where he spent a 32-year career in the area of biological magnetic resonance (EPR and NMR). He is the Series Editor for Biological Magnetic Resonance, which he launched in 1979.

Download or read book Biomedical EPR Part A Free Radicals Metals Medicine and Physiology written by Sandra S. Eaton and published by Springer Science & Business Media. This book was released on 2006-01-20 with total page 536 pages. Available in PDF, EPUB and Kindle. Book excerpt: Biomedical EPR – Part A focuses on applications of EPR spectroscopy in the areas of free radicals, metals, medicine, and physiology. The book celebrates the 70th birthday of Prof. James S. Hyde, Medical College of Wisconsin, and his contributions to this field. Chapters are written to provide introductory material for new-comers to the field which lead into up-to-date reviews that provide perspective on the wide range of questions that can be addressed by EPR. Key Features: Free Radicals in Medicine Radicals in vivo and in Model Systems, and their Study by Spin Trapping In vivo EPR, including Oximetry and Imaging Time Domain EPR at Radio Frequencies EPR of Copper Complexes: Motion and Frequency Dependence Time Domain EPR and Electron Spin Echo Envelope Modulation

Download or read book EPR Instrumental Methods written by Christopher J. Bender and published by Springer Science & Business Media. This book was released on 2012-12-06 with total page 444 pages. Available in PDF, EPUB and Kindle. Book excerpt: Electron magnetic resonance spectroscopy is undergoing something akin to a renaissance that is attributable to advances in microwave circuitry and signal processing software. EPR: Instrumental Methods is a textbook that brings the reader up to date on these advances and their role in providing better experimental techniques for biological magnetic resonance. Chapters in this book guide the reader from basic principles of spectrometer design through the advanced methods that are providing new vistas in disciplines such as oximetry, imaging, and structural biology. Key Features: Spectrometer design, particularly at low frequencies (below X-band), Design of spectrometer components unique to ENDOR and ESEEM, Optimization of EMR spectrometer sensitivity spanning many octaves, Algorithmic approach to spectral parameterization, Application of Fourier Methods to polymer conformation, oximetry, and imaging.

Download or read book Very High Frequency VHF ESR EPR written by Oleg Grinberg and published by Springer Science & Business Media. This book was released on 2013-11-09 with total page 583 pages. Available in PDF, EPUB and Kindle. Book excerpt: The field of Very High Frequency EPR (VHF EPR) or sometimes called Very High Field EPR (conveniently, also abbreviated as VHF EPR) has blossomed during the past decade, especially after the original pioneering work of Ya. S. Lebedev and his group at the Institute of Chemical Physics, Russian Academy of Sciences in Moscow. Although Lebedev suffered heavily under the economic constraints of the communist Soviet Union and then succumbed to cancer at the peak of his scientific career, his groundbreaking work from the 1970's is still considered today to be the 'gold standard' by researchers practicing EPR at high magnetic fields. A stimulus for the production of this book is the legacy of Yakov Levedev in his students now residing in academic positions in the US and elsewhere. The aim of this book is to highlight the state of this growing field. This is an attempt to cover the full scope of VHF EPR in a single volume. The idea for this volume came to the editors at the 2001 Rocky Mountain Analytical Conference during the 24th International EPR Symposium chaired by Sandra and Gareth Eaton. VHF EPR was presented as an independent research field at a workshop organized by LC BruneI and supported by the National High Magnetic Field Laboratory, a National Science Foundation funded facility at Florida State University.

Download or read book Biological Magnetic Resonance Volume 3 written by Lawrence J. Berliner and published by Springer Science & Business Media. This book was released on 2012-12-06 with total page 281 pages. Available in PDF, EPUB and Kindle. Book excerpt:

Download or read book Fluorescence Assay in Biology and Medicine written by Sidney Udenfriend and published by Academic Press. This book was released on 2014-05-27 with total page 673 pages. Available in PDF, EPUB and Kindle. Book excerpt: Molecular Biology: An International Series of Monographs and Textbooks: Fluorescence Assay in Biology and Medicine, Volume II covers the many applications of fluorescence and phosphorescence. This book discusses the principles of fluorescence polarization, comparison of luminescence methods of analysis, and direct measurement of fluorescence decay times. The photodecomposition, sulfhydryl compounds, determination of primary structure, and fluorescent staining are also deliberated. This text likewise covers the assay of purines in nucleic acid hydrolyzates, formyltetrahydrofolate synthetase, and ovarian hormones. This volume is valuable to chemists, physicists, and biophysicists intending to use fluorescence in studying reaction mechanisms and elucidate the structure of complex biopolymers.

Download or read book The Molecular Biology of the Bacilli written by David Dubnau and published by Elsevier. This book was released on 2012-12-02 with total page 276 pages. Available in PDF, EPUB and Kindle. Book excerpt: The Molecular Biology of the Bacilli: Volume II is a collection of material relevant to the basic knowledge of the bacillus system and to the development of the bacillus system for industrial applications. This volume presents bacillus research studies on the unique characteristics of bacilli and its interesting comparisons with other bacteria, specifically Escherichia coli. The first four chapters focus on the Bacillus subtilis, specifically the translational specificity, DNA repair, chemotaxis, and sporulation. Chapter 5 discusses the protoplast fusion in bacillus while Chapter 6 delves on the secretion of proteins by bacilli. Chapter 7 explores the function of bacilli as insecticide. Bacillus thuringiensis is also mentioned in this chapter. This topic is further discussed in Chapter 8 where the genetics and molecular biology of B. thuringiensis are discussed. This volume aims to be of help to students and researchers in various fields of biochemistry, genetics, biological sciences, and microbiology.

Download or read book Subject Catalog written by Library of Congress and published by . This book was released on with total page 1044 pages. Available in PDF, EPUB and Kindle. Book excerpt:

Download or read book Enzyme Catalysis and Regulation written by Gorden Hammes and published by Elsevier. This book was released on 2012-12-02 with total page 276 pages. Available in PDF, EPUB and Kindle. Book excerpt: Enzyme Catalysis and Regulation is an introduction to enzyme catalysis and regulation and covers topics ranging from protein structure and dynamics to steady-state enzyme kinetics, multienzyme complexes, and membrane-bound enzymes. Case studies of selected enzyme mechanisms are also presented. This book consists of 11 chapters and begins with a brief overview of enzyme structure, followed by a discussion on methods of probing enzyme structure such as X-ray crystallography and optical spectroscopy. Kinetic methods are then described, with emphasis on the general principles of steady-state and transient kinetics. The chemical principles involved in enzyme catalysis are also discussed, and case studies of a few well-documented enzymes are presented. The regulation of enzyme activity is analyzed from a nongenetic viewpoint, with particular reference to binding isotherms and models for allosterism. Two particular enzymes, aspartate transcarbamoylase and phosphofructokinase, are used as examples of well-studied regulatory enzymes. The last two chapters focus on multienzyme complexes and membrane-bound enzymes. This monograph is intended for graduate students, advanced undergraduates, and research workers in molecular biology and biochemistry.

Download or read book The Polysaccharides written by Gerald O. Aspinall and published by Academic Press. This book was released on 2014-07-01 with total page 524 pages. Available in PDF, EPUB and Kindle. Book excerpt: The Polysaccharides, Volume 2 is a seven-chapter text that presents the status of polysaccharide chemistry and related aspects of biochemistry. The opening chapter is concerned with the major classifications of polysaccharides, such as homoglycans and diheteroglycans. The succeeding five chapters discuss the occurrence, usage, structural studies, conformation, and derivatives of specific carbohydrate group, including cellulose, plant, algal, bacterial, and fungal polysaccharides. The last chapter deals with the industrial application and economic aspects of polysaccharides. This book will prove useful to chemists and biochemists working on polysaccharides and other complex carbohydrates.

Download or read book Calcium and Cell Function written by Wai Yiu Cheung and published by Academic Press. This book was released on 2013-09-03 with total page 450 pages. Available in PDF, EPUB and Kindle. Book excerpt: Calcium And Cell Function, Volume II covers the status of the multifunctional role of calcium in cell function. The book discusses the chemistry and metabolism of calcium, the various calcium-binding proteins in addition to calmodulin; and the functions of calcium, some mediated by calmodulin and some by other proteins. Physiologists, oncologists, and biochemists will find the book invaluable.

Download or read book Molecular Biology of Plant Tumors written by Günter Kahl and published by Academic Press. This book was released on 2014-06-28 with total page 644 pages. Available in PDF, EPUB and Kindle. Book excerpt: Molecular Biology of Plant Tumors provides an opportunity to learn in detail about the latest insights into the mechanism of transformation of plant cells by Agrobacterium tumefaciens. The study of the molecular mechanism responsible for the crown gall phenomenon (induced by Agrobacterium tumefaciens) illustrates the point that the fundamental study of the cause(s) and mechanism(s) of abnormal growth might be one of the most efficient ways to understand cellular differentiation and the molecular basis of gene expression. The book is organized into three parts that contain research on abnormal plant growth, crown gall tumors, and potential vectors for genetic engineering in agriculture. The genetic structure responsible for the neoplasmic transformation of plant cells in crown galls is a bacterial plasmid (called Ti for tumor-inducing). Research described in this volume demonstrates that these Ti plasmids were designed by evolution as natural gene vectors with which some bacteria can introduce active genes into plants. These transferred genes are maintained by integration in the plant genome and their expression is directly or indirectly responsible for the tumorous growth pattern.

Download or read book Protein Folding written by Charis Ghelis and published by Academic Press. This book was released on 2012-12-02 with total page 580 pages. Available in PDF, EPUB and Kindle. Book excerpt: Protein Folding aims to collect the most important information in the field of protein folding and probes the main principles that govern formation of the three-dimensional structure of a protein from a nascent polypeptide chain, as well as how the functional properties appear. This text is organized into three sections and consists of 15 chapters. After an introductory chapter where the main problems of protein folding are considered at the cellular level in the context of protein biosynthesis, the discussion turns to the conformation of native globular proteins. Definitions and rules of nomenclature are given, including the structural organization of globular proteins deduced from X-ray crystallographic data. Folding mechanisms are tentatively deduced from the observation of invariants in the architecture of folded proteins. The next chapters focus on the energetics of protein conformation and structure, indicating the principles of thermodynamic stability of the native structure, along with theoretical computation studies of protein folding, structure prediction, and folding simulation. The reader is also introduced to various experimental approaches; the reversibility of the unfolding-folding process; equilibrium and kinetic studies; and detection and characterization of intermediates in protein folding. This text concludes with a chapter dealing with problems specific to oligomeric proteins. This book is intended for research scientists, specialists, biochemists, and students of biochemistry and biology.